Drosophila melanogaster

34 known processes

path (Dmel_CG3424)

pathetic

(Aliases: anon-WO0118547.271,anon-WO0118547.370,Dmel\CG3424,CG3424)

path biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
tor signalingGO:0031929320.425
positive regulation of macromolecule metabolic processGO:00106044050.393
regulation of mitotic cell cycleGO:00073461900.354
growthGO:00400073590.354
cellular response to chemical stimulusGO:00708871990.352
regulation of growthGO:00400082330.332
negative regulation of cellular metabolic processGO:00313243820.332
cellular response to peptideGO:1901653280.288
insulin receptor signaling pathwayGO:0008286250.280
homeostatic processGO:00425921990.246
response to radiationGO:00093141550.235
regulation of mitotic cell cycle phase transitionGO:19019901300.233
er nucleus signaling pathwayGO:000698490.230
negative regulation of cell cycle phase transitionGO:19019881030.225
small molecule metabolic processGO:00442813050.203
regulation of insulin receptor signaling pathwayGO:0046626170.197
negative regulation of signalingGO:00230572190.195
negative regulation of macromolecule biosynthetic processGO:00105582700.187
regulation of intracellular signal transductionGO:19025312360.176
spermatogenesisGO:00072832000.174
lipid metabolic processGO:00066291210.173
transcription from rna polymerase ii promoterGO:00063663680.172
response to abiotic stimulusGO:00096283410.170
cell cycle phase transitionGO:00447701400.160
cellular response to starvationGO:0009267610.159
negative regulation of cell cycle processGO:00109481090.150
regulation of epithelial cell proliferationGO:005067840.150
regulation of tor signalingGO:0032006210.148
positive regulation of tor signalingGO:0032008130.141
single organism catabolic processGO:00447122280.137
cellular response to organic substanceGO:00713101320.136
cellular response to dna damage stimulusGO:00069742230.134
cellular response to nutrient levelsGO:0031669620.130
response to organic substanceGO:00100332840.129
cellular response to nitrogen compoundGO:1901699510.129
organelle fissionGO:00482853400.126
regulation of hippo signalingGO:0035330140.124
positive regulation of rna metabolic processGO:00512542710.121
positive regulation of gene expressionGO:00106282900.121
nuclear divisionGO:00002803320.121
positive regulation of nitrogen compound metabolic processGO:00511733540.119
agingGO:00075681430.117
Worm
positive regulation of nucleic acid templated transcriptionGO:19035082660.115
response to peptideGO:1901652290.114
negative regulation of mitotic cell cycle phase transitionGO:19019911030.113
hippo signalingGO:0035329200.113
negative regulation of developmental growthGO:0048640640.113
negative regulation of cell communicationGO:00106482230.109
positive regulation of rna biosynthetic processGO:19026802660.109
negative regulation of mitotic cell cycleGO:00459301090.106
negative regulation of growthGO:0045926840.106
circadian rhythmGO:00076231050.103
regulation of cell cycle phase transitionGO:19019871300.102
rhythmic processGO:00485111060.099
mitotic cell cycle phase transitionGO:00447721380.097
dna integrity checkpointGO:0031570810.096
cellular response to peptide hormone stimulusGO:0071375280.095
phosphorylationGO:00163102940.095
cellular response to oxygen containing compoundGO:1901701790.094
regulation of response to stressGO:00801342000.092
gene silencingGO:00164581380.092
positive regulation of cellular biosynthetic processGO:00313283160.091
oxoacid metabolic processGO:00434361030.091
regulation of cell cycle processGO:00105641810.090
organic acid transportGO:0015849180.089
posttranscriptional regulation of gene expressionGO:00106081450.088
regulation of cellular response to insulin stimulusGO:1900076170.087
regulation of cell growthGO:0001558430.084
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.083
positive regulation of nucleobase containing compound metabolic processGO:00459353320.082
regulation of transcription from rna polymerase ii promoterGO:00063573780.081
negative regulation of gene expressionGO:00106293870.080
protein phosphorylationGO:00064681690.079
enzyme linked receptor protein signaling pathwayGO:00071671790.077
positive regulation of phosphate metabolic processGO:00459371390.076
developmental growthGO:00485892800.073
regulation of cellular ketone metabolic processGO:001056530.073
positive regulation of growthGO:0045927750.071
cell proliferationGO:00082832990.070
positive regulation of signal transductionGO:00099672230.070
endocytosisGO:00068973100.067
regulation of macroautophagyGO:0016241150.067
organic substance catabolic processGO:19015753080.065
circadian behaviorGO:0048512760.065
regulation of gene expression epigeneticGO:00400291280.064
response to peptide hormoneGO:0043434290.064
response to light stimulusGO:00094161240.064
positive regulation of biosynthetic processGO:00098913160.063
deathGO:00162652840.063
response to nitrogen compoundGO:1901698900.063
negative regulation of nucleobase containing compound metabolic processGO:00459342610.063
regulation of cellular protein metabolic processGO:00322682430.063
mitotic nuclear divisionGO:00070672130.062
regulation of localizationGO:00328792750.062
regulation of cell cycleGO:00517262910.062
regulation of lipid metabolic processGO:0019216150.061
translational initiationGO:0006413110.061
cellular response to insulin stimulusGO:0032869280.060
positive regulation of cell growthGO:0030307190.059
cellular amino acid metabolic processGO:0006520610.059
locomotory behaviorGO:00076261760.058
positive regulation of signalingGO:00230562430.057
response to starvationGO:0042594970.057
protein complex assemblyGO:00064612000.055
purine nucleotide catabolic processGO:00061951090.053
single organism behaviorGO:00447083910.053
regulation of protein metabolic processGO:00512462560.053
regulation of synaptic growth at neuromuscular junctionGO:0008582890.052
chromosome organizationGO:00512763600.051
positive regulation of macromolecule biosynthetic processGO:00105572830.051
regulation of cellular catabolic processGO:00313291570.051
catabolic processGO:00090564090.051
triglyceride homeostasisGO:0070328180.050
regulation of steroid metabolic processGO:001921820.050
regulation of phosphorylationGO:00423251470.049
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.049
acylglycerol homeostasisGO:0055090190.048
negative regulation of erbb signaling pathwayGO:1901185290.047
regulation of phosphorus metabolic processGO:00511742100.047
regulation of imaginal disc growthGO:0045570260.046
positive regulation of transcription dna templatedGO:00458932660.045
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.045
organic acid metabolic processGO:00060821030.044
positive regulation of response to stimulusGO:00485843230.044
dna endoreduplicationGO:0042023220.044
lipid storageGO:0019915380.044
negative regulation of synapse assemblyGO:0051964390.044
negative regulation of signal transductionGO:00099682060.042
programmed cell deathGO:00125012570.042
posttranscriptional gene silencingGO:0016441460.042
organonitrogen compound metabolic processGO:19015643180.041
regulation of gene silencingGO:0060968630.041
carboxylic acid metabolic processGO:0019752920.040
nitrogen compound transportGO:0071705850.040
regulation of nervous system developmentGO:00519602480.040
response to extracellular stimulusGO:00099911160.040
response to oxygen containing compoundGO:19017002000.040
positive regulation of lipid biosynthetic processGO:004688930.039
negative regulation of response to stimulusGO:00485852580.039
regulation of developmental growthGO:00486381740.039
negative regulation of cell proliferationGO:0008285690.038
lipid localizationGO:0010876540.038
negative regulation of biosynthetic processGO:00098902770.037
ribonucleoside triphosphate catabolic processGO:00092031080.036
regulation of translationGO:0006417560.036
actin cytoskeleton organizationGO:00300362060.035
cholesterol homeostasisGO:004263230.035
l amino acid importGO:004309220.035
regulation of cell deathGO:00109411730.035
protein catabolic processGO:00301631010.035
positive regulation of cellular response to insulin stimulusGO:190007840.034
response to insulinGO:0032868290.034
gene silencing by rnaGO:0031047570.033
lipid homeostasisGO:0055088330.033
regulation of cell sizeGO:0008361630.033
regulation of cellular response to stressGO:0080135890.033
synapse assemblyGO:00074161430.033
negative regulation of cell differentiationGO:00455961430.033
positive regulation of phosphorus metabolic processGO:00105621390.033
extrinsic apoptotic signaling pathwayGO:009719110.032
ribonucleoside catabolic processGO:00424541120.032
positive regulation of developmental growthGO:0048639620.032
translationGO:0006412690.032
posttranscriptional gene silencing by rnaGO:0035194450.032
regulation of synapse structure and activityGO:00508031280.032
body morphogenesisGO:001017120.031
associative learningGO:0008306650.030
carbohydrate derivative catabolic processGO:19011361180.030
positive regulation of protein metabolic processGO:00512471280.030
regulation of cellular component biogenesisGO:00440872010.030
positive regulation of lipid metabolic processGO:004583440.029
cellular response to abiotic stimulusGO:0071214580.029
regulation of catalytic activityGO:00507901850.029
regulation of synapse assemblyGO:0051963940.029
cellular response to endogenous stimulusGO:0071495800.028
mitotic cell cycle checkpointGO:0007093880.028
apoptotic processGO:00069151590.028
response to endogenous stimulusGO:00097191190.028
positive regulation of lipid catabolic processGO:005099610.028
cellular protein modification processGO:00064644380.027
negative regulation of epithelial cell proliferationGO:005068040.027
positive regulation of cell communicationGO:00106472500.027
cellular response to radiationGO:0071478520.027
appendage morphogenesisGO:00351073970.027
olfactory behaviorGO:0042048970.027
proteasomal protein catabolic processGO:0010498590.027
regulation of molecular functionGO:00650092170.026
gastrulation with mouth forming firstGO:0001703360.026
response to organonitrogen compoundGO:0010243750.026
cell cycle dna replicationGO:0044786230.026
regulation of carbohydrate metabolic processGO:0006109100.025
single organism carbohydrate metabolic processGO:0044723720.025
regulation of chromosome organizationGO:0033044640.025
macromolecular complex assemblyGO:00650032560.025
drug transportGO:001589320.025
imaginal disc derived wing morphogenesisGO:00074763370.025
cellular ketone metabolic processGO:0042180240.025
dna damage checkpointGO:0000077780.025
ribonucleoside triphosphate metabolic processGO:00091991190.025
positive regulation of proteolysisGO:0045862520.025
autophagic vacuole assemblyGO:000004520.025
post embryonic appendage morphogenesisGO:00351203850.024
spindle organizationGO:00070512530.024
response to alcoholGO:0097305950.024
appendage developmentGO:00487364010.024
negative regulation of multicellular organismal processGO:00512411420.024
phagocytosisGO:00069092150.024
forebrain developmentGO:003090020.024
intracellular signal transductionGO:00355563000.024
synaptic growth at neuromuscular junctionGO:00511241190.024
nucleoside phosphate metabolic processGO:00067531620.024
regulation of mitosisGO:0007088560.023
wing disc morphogenesisGO:00074723440.023
chromatin organizationGO:00063252070.023
gene silencing by mirnaGO:0035195220.023
negative regulation of cellular biosynthetic processGO:00313272770.023
negative regulation of nitrogen compound metabolic processGO:00511722650.022
purine ribonucleotide metabolic processGO:00091501450.022
positive regulation of programmed cell deathGO:0043068620.022
mitotic dna damage checkpointGO:0044773740.022
cell cycle checkpointGO:0000075950.022
proteolysis involved in cellular protein catabolic processGO:0051603830.022
negative regulation of rna metabolic processGO:00512532510.022
single organism intracellular transportGO:19025822070.022
response to other organismGO:00517072930.022
cellular carbohydrate metabolic processGO:0044262220.022
cellular response to external stimulusGO:0071496660.022
neuropeptide signaling pathwayGO:0007218450.022
positive regulation of catabolic processGO:00098961050.022
regulation of response to nutrient levelsGO:0032107180.022
cellular lipid metabolic processGO:0044255830.022
ribonucleoprotein complex subunit organizationGO:0071826280.021
positive regulation of apoptotic processGO:0043065470.021
regulation of catabolic processGO:00098941700.021
regulation of apoptotic processGO:00429811300.021
cellular response to sterol depletionGO:007150130.021
organic substance transportGO:00717022570.021
regulation of cell divisionGO:0051302720.021
response to external biotic stimulusGO:00432072930.021
neutral lipid biosynthetic processGO:004646020.021
imaginal disc derived appendage morphogenesisGO:00351143950.021
nucleotide catabolic processGO:00091661090.020
regulation of programmed cell deathGO:00430671520.020
cellular catabolic processGO:00442483720.020
mitotic spindle organizationGO:00070522200.020
single organism biosynthetic processGO:00447112060.020
negative regulation of translationGO:0017148280.020
positive regulation of molecular functionGO:00440931360.020
regulation of phosphate metabolic processGO:00192202100.020
negative regulation of cell deathGO:0060548810.020
positive regulation of cellular protein metabolic processGO:00322701180.020
imaginal disc derived appendage developmentGO:00487373990.020
purine containing compound metabolic processGO:00725211550.020
nucleobase containing small molecule metabolic processGO:00550861740.020
generation of precursor metabolites and energyGO:0006091420.020
regulation of anatomical structure sizeGO:00900661630.020
chemical homeostasisGO:0048878920.020
negative regulation of insulin receptor signaling pathwayGO:0046627110.019
organic cyclic compound catabolic processGO:19013611680.019
regulation of g1 s transition of mitotic cell cycleGO:2000045230.019
response to nutrient levelsGO:00316671140.019
sister chromatid segregationGO:0000819920.019
rna processingGO:00063961470.019
negative regulation of rna biosynthetic processGO:19026792400.018
amino acid importGO:004309050.018
male gamete generationGO:00482322010.018
behavioral response to ethanolGO:0048149490.018
cell divisionGO:00513012480.018
negative regulation of protein metabolic processGO:0051248850.018
adult behaviorGO:00305341370.018
actin filament organizationGO:00070151260.018
positive regulation of cell sizeGO:0045793210.018
neuromuscular junction developmentGO:00075281490.017
g2 m transition of mitotic cell cycleGO:0000086190.017
regulation of synapse organizationGO:00508071100.017
purine nucleoside metabolic processGO:00422781270.017
sex determinationGO:0007530180.017
rhythmic behaviorGO:0007622760.017
cell deathGO:00082192790.017
long chain fatty acid metabolic processGO:000167630.017
positive regulation of catalytic activityGO:00430851180.017
cellular response to topologically incorrect proteinGO:0035967100.017
cell cycle g1 s phase transitionGO:0044843310.017
negative regulation of catalytic activityGO:0043086420.017
protein localization to organelleGO:0033365820.017
positive regulation of developmental processGO:00510941430.017
nucleoside metabolic processGO:00091161270.017
positive regulation of cell cycle g2 m phase transitionGO:190275120.017
purine ribonucleoside metabolic processGO:00461281270.017
protein heterooligomerizationGO:005129140.017
regulation of organ growthGO:0046620420.017
protein complex biogenesisGO:00702712010.016
gtp catabolic processGO:0006184720.016
regulation of phosphatidylinositol 3 kinase signalingGO:001406640.016
protein localizationGO:00081042840.016
negative regulation of intracellular signal transductionGO:1902532570.016
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.016
chromatin assemblyGO:0031497480.016
anion transmembrane transportGO:0098656260.016
autophagyGO:00069141080.016
purine nucleoside catabolic processGO:00061521120.016
monocarboxylic acid metabolic processGO:0032787290.016
cellular response to organonitrogen compoundGO:0071417360.016
chromosome segregationGO:00070591570.016
monocarboxylic acid catabolic processGO:0072329100.016
ion transportGO:00068111450.015
positive regulation of cell deathGO:0010942690.015
modification dependent protein catabolic processGO:0019941780.015
developmental programmed cell deathGO:00106231380.015
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.015
tube morphogenesisGO:00352391910.015
positive regulation of cellular amine metabolic processGO:003324000.015
skeletal muscle adaptationGO:004350110.015
regulation of chromosome segregationGO:0051983320.015
innate immune responseGO:00450871440.015
g1 s transition of mitotic cell cycleGO:0000082310.015
negative regulation of nervous system developmentGO:0051961920.015
nuclear transportGO:0051169720.015
lipid biosynthetic processGO:0008610460.015
negative regulation of phosphatidylinositol 3 kinase signalingGO:001406740.015
response to topologically incorrect proteinGO:0035966100.015
positive regulation of intracellular signal transductionGO:19025331160.015
nucleotide metabolic processGO:00091171610.015
positive regulation of cellular catabolic processGO:0031331950.015
regulation of cellular amine metabolic processGO:003323830.015
cellular carbohydrate catabolic processGO:004427520.015
regulation of stress activated mapk cascadeGO:0032872410.015
organic anion transportGO:0015711280.014
xenobiotic transportGO:004290810.014
negative regulation of molecular functionGO:0044092510.014
small gtpase mediated signal transductionGO:0007264880.014
intrinsic apoptotic signaling pathway by p53 class mediatorGO:007233250.014
maintenance of locationGO:0051235730.014
response to bacteriumGO:00096171980.014
response to glucoseGO:000974920.014
photoreceptor cell fate specificationGO:004370490.014
carboxylic acid transportGO:0046942180.014
lateral inhibitionGO:00463312060.014
response to hexoseGO:000974630.014
energy derivation by oxidation of organic compoundsGO:0015980320.014
cellular response to hormone stimulusGO:0032870440.014
cell motilityGO:00488702510.014
cellular response to decreased oxygen levelsGO:0036294300.014
proteolysisGO:00065081920.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
ubiquitin homeostasisGO:001099210.014
neurological system processGO:00508773580.014
negative regulation of cell developmentGO:0010721620.014
nucleoside phosphate catabolic processGO:19012921100.014
glycosyl compound catabolic processGO:19016581120.014
response to hormoneGO:0009725450.014
signal transduction by phosphorylationGO:00230141070.014
glycosyl compound metabolic processGO:19016571270.013
negative regulation of cell cycleGO:00457861160.013
nucleoside triphosphate catabolic processGO:00091431080.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
stress activated protein kinase signaling cascadeGO:0031098550.013
regulation of cell proliferationGO:00421271630.013
negative regulation of organ growthGO:0046621150.013
cellular nitrogen compound catabolic processGO:00442701650.013
peptidyl proline hydroxylationGO:001951110.013
negative regulation of transcription dna templatedGO:00458922370.013
regulation of nuclear divisionGO:0051783580.013
carbohydrate metabolic processGO:0005975820.013
negative regulation of developmental processGO:00510932010.013
cellular amine metabolic processGO:0044106120.013
purine containing compound catabolic processGO:00725231120.013
regulation of polysaccharide biosynthetic processGO:003288510.013
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.013
negative regulation of phosphorus metabolic processGO:0010563450.013
cell cell signaling involved in cell fate commitmentGO:00451682100.013
eye morphogenesisGO:00485922600.013
mitotic dna integrity checkpointGO:0044774750.013
regulation of nucleoside metabolic processGO:0009118500.013
ribonucleotide metabolic processGO:00092591450.013
disaccharide metabolic processGO:000598440.013
single organism nuclear importGO:1902593510.013
cell cycle g2 m phase transitionGO:0044839220.013
organophosphate catabolic processGO:00464341120.013
chromatin modificationGO:00165681470.012
regulation of multicellular organismal developmentGO:20000264140.012
response to uvGO:0009411240.012
entry into diapauseGO:005511510.012
hormone catabolic processGO:004244730.012
rna interferenceGO:0016246270.012
regulation of lipid transportGO:003236830.012
negative regulation of neuroblast proliferationGO:0007406270.012
epithelial cell developmentGO:00020642740.012
regulation of cellular component sizeGO:0032535980.012
regulation of meiosisGO:004002030.012
inositol lipid mediated signalingGO:004801740.012
positive regulation of glycogen biosynthetic processGO:004572510.012
protein importGO:0017038550.012
rna transportGO:0050658460.012
regulation of organelle organizationGO:00330431960.012
salivary gland histolysisGO:0035070880.012
purine ribonucleotide catabolic processGO:00091541090.012
compound eye developmentGO:00487493070.012
glandular epithelial cell differentiationGO:000206710.012
positive regulation of cell divisionGO:0051781160.012
dendrite developmentGO:00163582040.012
protein import into nucleusGO:0006606510.012
positive regulation of insulin receptor signaling pathwayGO:004662830.011
endoplasmic reticulum unfolded protein responseGO:003096860.011
regulation of nucleocytoplasmic transportGO:0046822350.011
mitotic g2 m transition checkpointGO:0044818700.011
germline stem cell asymmetric divisionGO:0098728150.011
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.011
positive regulation of mapk cascadeGO:0043410630.011
establishment of localization in cellGO:00516494020.011
cytoplasmic transport nurse cell to oocyteGO:0007303120.011
regulation of response to extracellular stimulusGO:0032104180.011
regulation of cellular localizationGO:00603411360.011
multicellular organismal agingGO:00102591400.011
Worm
nucleoside monophosphate catabolic processGO:0009125390.011
mitotic sister chromatid segregationGO:0000070870.011
spindle assemblyGO:0051225800.011
sterol homeostasisGO:005509240.011
protein modification processGO:00362114380.011
regulation of apoptotic signaling pathwayGO:2001233100.011
organ growthGO:0035265560.011
response to decreased oxygen levelsGO:0036293580.011
regulation of hydrolase activityGO:0051336970.011
positive regulation of phosphorylationGO:0042327870.011
pole cell developmentGO:0007277260.011
phosphatidylinositol 3 kinase signalingGO:001406540.011
actin filament based processGO:00300292200.011
regulation of rna splicingGO:0043484690.011
fatty acid beta oxidationGO:000663560.011
nucleoside catabolic processGO:00091641120.011
establishment of rna localizationGO:0051236470.011
regulation of cellular response to hypoxiaGO:190003730.011
response to sterolGO:0036314340.011
negative regulation of hippo signalingGO:003533150.010
regulation of cell differentiationGO:00455953020.010
response to biotic stimulusGO:00096072940.010
gtp metabolic processGO:0046039720.010
eggshell chorion assemblyGO:0007306660.010
tissue morphogenesisGO:00487292970.010
telencephalon developmentGO:002153720.010
regulation of response to dna damage stimulusGO:2001020230.010
macromolecule catabolic processGO:00090571610.010
immune system processGO:00023763470.010
dendrite morphogenesisGO:00488131990.010
amino acid transportGO:0006865120.010
positive regulation of jun kinase activityGO:004350740.010
regulation of multicellular organism growthGO:0040014400.010
purine ribonucleoside monophosphate catabolic processGO:0009169380.010
positive regulation of cellular protein catabolic processGO:1903364240.010

path disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.038
hair diseaseDOID:42100.016
integumentary system diseaseDOID:1600.016
cancerDOID:16200.012
disease of cellular proliferationDOID:1456600.012
nervous system diseaseDOID:86300.011
organ system cancerDOID:005068600.011
disease of metabolismDOID:001466700.011
carbohydrate metabolism diseaseDOID:005001300.011
diabetes mellitusDOID:935100.011
glucose metabolism diseaseDOID:419400.011
acquired metabolic diseaseDOID:006015800.011
large intestine cancerDOID:567200.010
colon cancerDOID:21900.010
colorectal cancerDOID:925600.010
intestinal cancerDOID:1015500.010
gastrointestinal system cancerDOID:311900.010