Drosophila melanogaster

37 known processes

scw (Dmel_CG31695)

screw

(Aliases: l(2)IG76,CG31695,Dmel\CG31695,l(2)37Ff,BcDNA:LD30945,SCW,Scw)

scw biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
torso signaling pathwayGO:0008293210.848
anterior posterior pattern specificationGO:00099521360.762
regionalizationGO:00030024160.744
positive regulation of nitrogen compound metabolic processGO:00511733540.739
Human Mouse
terminal region determinationGO:0007362250.531
appendage morphogenesisGO:00351073970.498
Mouse Fly
stem cell differentiationGO:00488631170.453
Human Mouse
embryonic development via the syncytial blastodermGO:00017001480.438
segmentationGO:00352822070.420
digestive tract morphogenesisGO:00485461270.398
Zebrafish Mouse
positive regulation of gene expressionGO:00106282900.357
Human Mouse
tissue morphogenesisGO:00487292970.354
Zebrafish Mouse
renal tubule developmentGO:0061326640.351
malpighian tubule morphogenesisGO:0007443440.346
heart developmentGO:0007507820.345
Zebrafish
zygotic determination of anterior posterior axis embryoGO:0007354270.340
anterior posterior axis specification embryoGO:00085951030.319
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.310
Human
tube developmentGO:00352952440.310
Zebrafish Mouse
positive regulation of rna biosynthetic processGO:19026802660.302
Human Mouse
regulation of muscle organ developmentGO:0048634130.300
Fly
embryonic morphogenesisGO:00485982060.298
Zebrafish Mouse
positive regulation of macromolecule metabolic processGO:00106044050.296
Human Mouse
tube morphogenesisGO:00352391910.291
Zebrafish Mouse
positive regulation of nucleobase containing compound metabolic processGO:00459353320.290
Human Mouse
embryonic pattern specificationGO:00098801740.288
Mouse
morphogenesis of an epitheliumGO:00020092760.280
Zebrafish Mouse
midgut developmentGO:0007494230.246
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.246
Human
ameboidal type cell migrationGO:00016671510.233
localization of cellGO:00516742570.221
cardioblast differentiationGO:0010002200.210
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.198
Human Mouse
renal system developmentGO:0072001720.197
Human Mouse
enzyme linked receptor protein signaling pathwayGO:00071671790.196
Human Zebrafish Mouse
negative regulation of biosynthetic processGO:00098902770.196
Human
nephron developmentGO:007200630.193
Human Mouse
negative regulation of cellular biosynthetic processGO:00313272770.191
Human
columnar cuboidal epithelial cell differentiationGO:00020652560.189
Human Fly
embryonic hindgut morphogenesisGO:0048619480.187
transcription from rna polymerase ii promoterGO:00063663680.184
Human Zebrafish Mouse
embryonic axis specificationGO:00005781070.184
wing disc morphogenesisGO:00074723440.183
Fly
positive regulation of rna metabolic processGO:00512542710.183
Human Mouse
blastoderm segmentationGO:00073501590.182
positive regulation of transcription dna templatedGO:00458932660.180
Human Mouse
positive regulation of macromolecule biosynthetic processGO:00105572830.179
Human Mouse
tripartite regional subdivisionGO:00073511030.177
nephron epithelium developmentGO:007200930.177
positive regulation of cellular biosynthetic processGO:00313283160.167
Human Mouse
anterior posterior axis specificationGO:00099481090.163
kidney developmentGO:000182230.151
Human Mouse
imaginal disc derived appendage morphogenesisGO:00351143950.145
Fly
imaginal disc derived wing morphogenesisGO:00074763370.139
Fly
dorsal closureGO:0007391790.138
negative regulation of nucleic acid templated transcriptionGO:19035072400.137
Human
regulation of embryonic developmentGO:0045995680.137
Zebrafish Mouse
cell motilityGO:00488702510.135
mitotic nuclear divisionGO:00070672130.130
Human
nephron tubule developmentGO:007208030.130
muscle structure developmentGO:00610612240.129
Fly
catabolic processGO:00090564090.128
heart morphogenesisGO:0003007320.122
Zebrafish
organelle fissionGO:00482853400.121
Human
digestive tract mesoderm developmentGO:000750250.116
cellular response to chemical stimulusGO:00708871990.114
Human
epithelial cell differentiationGO:00308553220.114
Human Mouse Fly
head involutionGO:0008258350.110
cell migrationGO:00164772380.109
epithelial cell developmentGO:00020642740.107
Human Fly
chemotaxisGO:00069352490.106
Mouse
morphogenesis of embryonic epitheliumGO:0016331940.105
Mouse
negative regulation of transcription dna templatedGO:00458922370.104
Human
cell cycle dna replicationGO:0044786230.104
compound eye morphogenesisGO:00017452490.103
establishment of organelle localizationGO:00516561220.103
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.103
Human Zebrafish Mouse
appendage developmentGO:00487364010.103
Mouse Fly
nephron morphogenesisGO:007202830.102
Mouse
axis specificationGO:00097981670.101
chorion containing eggshell formationGO:00073041050.098
negative regulation of rna metabolic processGO:00512532510.098
Human
kidney morphogenesisGO:006099330.097
Mouse
compound eye developmentGO:00487493070.094
neuron projection guidanceGO:00974852410.094
Mouse
growthGO:00400073590.094
Fly
organic substance catabolic processGO:19015753080.093
regulation of molecular functionGO:00650092170.093
Human
regulation of transcription from rna polymerase ii promoterGO:00063573780.091
Human Zebrafish Mouse
negative regulation of gene expressionGO:00106293870.090
regulation of cytoskeleton organizationGO:0051493890.090
bmp signaling pathwayGO:0030509270.090
Human Zebrafish Mouse
circulatory system developmentGO:0072359820.089
Human Zebrafish
negative regulation of cellular metabolic processGO:00313243820.084
Human
positive regulation of nucleic acid templated transcriptionGO:19035082660.082
Human Mouse
hindgut morphogenesisGO:0007442580.080
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.079
cellular ketone metabolic processGO:0042180240.079
Human
regulation of organelle organizationGO:00330431960.078
Human
response to external biotic stimulusGO:00432072930.076
ovarian follicle cell developmentGO:00307072480.076
Fly
eye morphogenesisGO:00485922600.075
Mouse
embryonic organ developmentGO:0048568500.075
Zebrafish Mouse
digestive system developmentGO:00551231490.074
Zebrafish Mouse
body morphogenesisGO:001017120.073
regulation of multicellular organismal developmentGO:20000264140.070
Human Zebrafish Mouse Fly
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.070
Human Mouse
motor neuron axon guidanceGO:0008045580.069
negative regulation of cell differentiationGO:00455961430.068
Human Zebrafish Mouse
cellular response to organic substanceGO:00713101320.068
Human
g protein coupled receptor signaling pathwayGO:00071861360.066
nephron tubule morphogenesisGO:007207830.066
sensory organ morphogenesisGO:00905962600.065
Mouse
regulation of mitotic cell cycleGO:00073461900.065
Human
salivary gland developmentGO:00074311620.065
Mouse
nephron epithelium morphogenesisGO:007208830.065
cell divisionGO:00513012480.062
Human
cardiac cell fate commitmentGO:0060911170.061
response to alcoholGO:0097305950.061
gland developmentGO:00487321910.060
Mouse
gland morphogenesisGO:00226121450.058
Mouse
positive regulation of response to stimulusGO:00485843230.058
Human Mouse
small molecule metabolic processGO:00442813050.058
Human
single organism catabolic processGO:00447122280.057
spindle organizationGO:00070512530.056
regulation of apoptotic processGO:00429811300.054
Mouse
urogenital system developmentGO:0001655720.054
Human Mouse
single organism biosynthetic processGO:00447112060.054
Human
dorsal ventral pattern formationGO:00099531330.053
cellular protein localizationGO:00346131600.053
Human
connective tissue developmentGO:006144830.053
Human
imaginal disc derived appendage developmentGO:00487373990.053
Fly
positive regulation of developmental growthGO:0048639620.053
Fly
response to lipopolysaccharideGO:003249640.052
cardiovascular system developmentGO:0072358820.052
Human Zebrafish
cell maturationGO:00484691440.052
gastrulationGO:0007369700.051
Zebrafish Mouse
negative regulation of signalingGO:00230572190.050
Human Mouse
digestive tract developmentGO:00485651490.050
Zebrafish Mouse
cell fate specificationGO:0001708710.050
Zebrafish
lateral inhibitionGO:00463312060.049
negative regulation of rna biosynthetic processGO:19026792400.049
Human
tissue migrationGO:00901301550.049
nuclear divisionGO:00002803320.048
Human
imaginal disc pattern formationGO:0007447910.048
Fly
endodermal cell fate commitmentGO:000171130.048
Zebrafish
positive regulation of developmental processGO:00510941430.047
Human Mouse Fly
male gamete generationGO:00482322010.047
Mouse
formation of primary germ layerGO:0001704240.047
Zebrafish Mouse
epithelial tube morphogenesisGO:0060562880.045
Zebrafish Mouse
mesenchymal cell differentiationGO:004876210.045
Human
anatomical structure homeostasisGO:0060249970.045
deathGO:00162652840.043
Human Mouse
mesoderm developmentGO:0007498780.042
regulation of catalytic activityGO:00507901850.042
Human
positive regulation of biosynthetic processGO:00098913160.042
Human Mouse
kidney epithelium developmentGO:007207330.042
Mouse
cardioblast cell fate commitmentGO:0042684140.041
exocrine system developmentGO:00352721620.041
Mouse
cell cell signaling involved in cell fate commitmentGO:00451682100.041
regulation of cellular component biogenesisGO:00440872010.041
Human Fly
epithelial cell migrationGO:00106311480.041
regulation of steroid metabolic processGO:001921820.041
Human
renal tubule morphogenesisGO:0061333440.040
protein modification processGO:00362114380.040
Human Mouse
cardiocyte differentiationGO:0035051290.040
cellular macromolecule localizationGO:00707272200.040
Human
cellular catabolic processGO:00442483720.039
regulation of organ morphogenesisGO:2000027780.038
Mouse
mitotic spindle organizationGO:00070522200.038
leg disc developmentGO:0035218920.038
regulation of developmental growthGO:00486381740.038
Fly
proteolysisGO:00065081920.037
regulation of decapentaplegic signaling pathwayGO:009009780.036
axonogenesisGO:00074092900.036
Mouse
regulation of mitotic cell cycle phase transitionGO:19019901300.036
negative regulation of macromolecule biosynthetic processGO:00105582700.036
Human
regulation of cell cycle phase transitionGO:19019871300.035
mitotic cytokinesisGO:0000281500.035
regulation of cell proliferationGO:00421271630.035
Human Mouse
mitotic cell cycle phase transitionGO:00447721380.034
negative regulation of signal transductionGO:00099682060.034
Human Mouse
dendrite developmentGO:00163582040.034
Human
intracellular signal transductionGO:00355563000.034
Human Mouse
salivary gland morphogenesisGO:00074351450.033
Mouse
negative regulation of growthGO:0045926840.033
positive regulation of cell communicationGO:00106472500.031
Human Mouse
negative regulation of cell communicationGO:00106482230.031
Human Mouse
ribonucleoside triphosphate catabolic processGO:00092031080.031
cell proliferationGO:00082832990.031
Human Mouse
anterior posterior pattern specification imaginal discGO:0007448160.031
gastrulation with mouth forming firstGO:0001703360.031
oocyte developmentGO:00485991240.030
heart processGO:0003015370.030
myotube differentiationGO:0014902460.030
negative regulation of nucleobase containing compound metabolic processGO:00459342610.030
Human
regulation of synapse structure and activityGO:00508031280.030
Fly
eggshell formationGO:00307031050.030
wing disc pattern formationGO:0035222660.029
Fly
regulation of stress activated protein kinase signaling cascadeGO:0070302420.029
muscle organ developmentGO:00075171270.028
Fly
purine containing compound metabolic processGO:00725211550.028
somatic muscle developmentGO:0007525660.028
positive regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:009010090.028
Human Mouse
positive regulation of catalytic activityGO:00430851180.028
cell cycle checkpointGO:0000075950.027
epithelium migrationGO:00901321480.027
regulation of wnt signaling pathwayGO:0030111680.027
developmental maturationGO:00217001720.027
taxisGO:00423303040.026
Mouse
regulation of intracellular signal transductionGO:19025312360.026
Human Mouse
cellular response to endogenous stimulusGO:0071495800.026
Human
myotube cell developmentGO:001490430.026
response to endogenous stimulusGO:00097191190.026
Human
response to organic substanceGO:00100332840.026
Human
regulation of cellular amino acid metabolic processGO:000652100.026
protein complex biogenesisGO:00702712010.026
Zebrafish
columnar cuboidal epithelial cell developmentGO:00020662490.025
Human Fly
response to abiotic stimulusGO:00096283410.025
circulatory system processGO:0003013370.024
response to other organismGO:00517072930.024
regulation of phosphorus metabolic processGO:00511742100.023
Human Mouse
positive regulation of cell motilityGO:200014730.023
regulation of cell differentiationGO:00455953020.023
Human Zebrafish Mouse
cuticle developmentGO:0042335860.023
axon guidanceGO:00074112330.023
Mouse
regulation of cellular ketone metabolic processGO:001056530.023
Human
epithelial structure maintenanceGO:0010669170.023
regulation of cardioblast differentiationGO:005189090.023
post embryonic appendage morphogenesisGO:00351203850.023
Fly
positive regulation of signal transductionGO:00099672230.022
Human Mouse
mapk cascadeGO:00001651070.022
Human Mouse
positive regulation of phosphorus metabolic processGO:00105621390.022
Human Mouse
carbohydrate derivative metabolic processGO:19011352170.022
stress activated protein kinase signaling cascadeGO:0031098550.022
negative regulation of molecular functionGO:0044092510.022
Human
determination of dorsal ventral asymmetryGO:004826230.021
Zebrafish
intracellular mrna localization involved in pattern specification processGO:0060810560.021
embryo development ending in birth or egg hatchingGO:00097921520.021
Mouse
locomotory behaviorGO:00076261760.021
purine ribonucleotide metabolic processGO:00091501450.021
positive regulation of molecular functionGO:00440931360.021
regulation of bmp signaling pathwayGO:0030510230.021
neuron recognitionGO:00080381010.021
positive regulation of gtp catabolic processGO:0033126430.021
organonitrogen compound metabolic processGO:19015643180.020
oocyte dorsal ventral axis specificationGO:0007310340.020
regulation of growthGO:00400082330.020
Fly
organic cyclic compound catabolic processGO:19013611680.020
regulation of programmed cell deathGO:00430671520.020
Mouse
mesoderm formationGO:0001707210.019
Mouse
cell growthGO:00160491080.019
autophagic cell deathGO:0048102830.019
camera type eye morphogenesisGO:004859320.019
Mouse
imaginal disc derived wing vein morphogenesisGO:0008586440.019
Fly
cellular protein complex assemblyGO:0043623710.018
positive regulation of cellular amino acid metabolic processGO:004576400.018
endodermal cell differentiationGO:003598730.018
Zebrafish
eye developmentGO:00016543230.018
Mouse
axon developmentGO:00615642970.018
Mouse
protein catabolic processGO:00301631010.018
regulation of striated muscle tissue developmentGO:001620250.018
hindgut developmentGO:0061525580.018
macromolecular complex assemblyGO:00650032560.018
Zebrafish
chromosome segregationGO:00070591570.018
regulation of cell cycleGO:00517262910.018
Human
immune system processGO:00023763470.018
Human
wound healingGO:0042060750.017
endoderm developmentGO:000749260.017
Zebrafish
detection of stimulusGO:00516061560.017
negative regulation of nitrogen compound metabolic processGO:00511722650.017
Human
salivary gland cell autophagic cell deathGO:0035071830.017
positive regulation of hydrolase activityGO:0051345780.017
ribonucleotide metabolic processGO:00092591450.017
protein complex assemblyGO:00064612000.017
Zebrafish
regulation of stem cell proliferationGO:0072091400.017
stem cell divisionGO:0017145690.017
regulation of cell cycle processGO:00105641810.016
Human
cardiac cell fate determinationGO:006091330.016
regulation of cell cycle g1 s phase transitionGO:1902806230.016
regulation of cellular amine metabolic processGO:003323830.016
stress activated mapk cascadeGO:0051403520.016
developmental growthGO:00485892800.016
Fly
cell type specific apoptotic processGO:0097285380.016
Mouse
regulation of synapse organizationGO:00508071100.016
Fly
regulation of immune system processGO:00026821760.016
positive regulation of cell migrationGO:003033520.016
head developmentGO:00603221350.016
neuromuscular junction developmentGO:00075281490.016
Fly
embryonic digestive tract developmentGO:004856650.016
maternal determination of anterior posterior axis embryoGO:0008358740.016
negative regulation of cell cycle processGO:00109481090.016
Human
negative regulation of hormone biosynthetic processGO:003235310.015
Human
oocyte constructionGO:00073081120.015
cellular response to biotic stimulusGO:007121640.015
positive regulation of organelle organizationGO:0010638650.015
response to bacteriumGO:00096171980.015
embryonic heart tube developmentGO:0035050220.015
Zebrafish
negative regulation of programmed cell deathGO:0043069720.015
Mouse
macromolecule catabolic processGO:00090571610.015
amine metabolic processGO:0009308120.015
response to light stimulusGO:00094161240.015
positive regulation of nucleotide metabolic processGO:0045981550.015
negative regulation of cell cycle phase transitionGO:19019881030.014
hormone biosynthetic processGO:0042446200.014
Human
germ band shorteningGO:0007390190.014
regulation of multi organism processGO:00439001310.014
stem cell developmentGO:0048864790.014
Mouse
chromosome organizationGO:00512763600.014
ribose phosphate metabolic processGO:00196931450.014
tissue homeostasisGO:0001894360.014
negative regulation of mitotic cell cycleGO:00459301090.014
Human
protein localization to nucleusGO:0034504550.014
Human
histolysisGO:00075591020.014
positive regulation of phosphate metabolic processGO:00459371390.014
Human Mouse
cellular response to transforming growth factor beta stimulusGO:0071560180.014
regulation of phosphate metabolic processGO:00192202100.014
Human Mouse
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.013
regulation of map kinase activityGO:0043405170.013
Human
response to biotic stimulusGO:00096072940.013
positive regulation of intracellular signal transductionGO:19025331160.013
adult behaviorGO:00305341370.013
skeletal muscle fiber developmentGO:004874130.013
reproductive structure developmentGO:0048608740.013
jnk cascadeGO:0007254500.013
cellular hormone metabolic processGO:0034754230.013
Human
chitin based cuticle developmentGO:0040003490.013
response to sterolGO:0036314340.013
synapse assemblyGO:00074161430.013
Fly
erbb signaling pathwayGO:0038127580.013
oocyte differentiationGO:00099941450.013
development of primary sexual characteristicsGO:0045137500.013
oxoacid metabolic processGO:00434361030.013
centrosome duplicationGO:00512981210.013
salivary gland histolysisGO:0035070880.013
membrane organizationGO:00610241120.013
dorsal ventral axis specificationGO:0009950660.013
establishment of protein localizationGO:00451841630.012
mesodermal cell migrationGO:000807870.012
modification dependent protein catabolic processGO:0019941780.012
purine containing compound catabolic processGO:00725231120.012
cellular response to lipidGO:0071396200.012
Human
regulation of microtubule based processGO:0032886490.012
multicellular organism growthGO:0035264460.012
regulation of hydrolase activityGO:0051336970.012
chitin based embryonic cuticle biosynthetic processGO:0008362160.012
positive regulation of purine nucleotide metabolic processGO:1900544550.012
regulation of localizationGO:00328792750.012
Human Fly
smoothened signaling pathwayGO:0007224490.012
organic hydroxy compound metabolic processGO:1901615830.012
Human
protein transportGO:00150311550.012
cell cycle phase transitionGO:00447701400.012
muscle tissue morphogenesisGO:006041520.012
regulation of catabolic processGO:00098941700.012
establishment or maintenance of cell polarityGO:00071631670.012
positive regulation of cell deathGO:0010942690.012
Mouse
organelle assemblyGO:00709251980.012
cellular protein modification processGO:00064644380.012
Human Mouse
regulation of nucleotide metabolic processGO:0006140620.012
locomotor rhythmGO:0045475560.012
positive regulation of multi organism processGO:0043902400.011
dendrite morphogenesisGO:00488131990.011
response to ecdysoneGO:0035075340.011
cell cycle g1 s phase transitionGO:0044843310.011
cellular response to radiationGO:0071478520.011
defense response to other organismGO:00985422250.011
imaginal disc derived wing vein specificationGO:0007474480.011
Fly
organic acid metabolic processGO:00060821030.011
adult locomotory behaviorGO:0008344760.011
positive regulation of signalingGO:00230562430.011
Human Mouse
convergent extension involved in gastrulationGO:006002720.011
phagocytosisGO:00069092150.011
sensory perception of smellGO:0007608800.011
gastrulation involving germ band extensionGO:0010004360.011
negative regulation of response to stimulusGO:00485852580.010
Human Mouse
oocyte axis specificationGO:00073091080.010
determination of imaginal disc primordiumGO:0007445110.010
regulation of kinase activityGO:0043549530.010
Human
actin filament based processGO:00300292200.010
immune response activating signal transductionGO:000275720.010
reproductive system developmentGO:0061458740.010
aggressive behaviorGO:0002118630.010
mesenchymal cell developmentGO:001403110.010
leg disc morphogenesisGO:0007478800.010
feeding behaviorGO:0007631500.010
intracellular mrna localizationGO:0008298660.010
organophosphate metabolic processGO:00196371950.010
fertilizationGO:0009566260.010
regulation of stress activated mapk cascadeGO:0032872410.010

scw disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cardiovascular system diseaseDOID:128700.122
congenital heart diseaseDOID:168200.122
heart diseaseDOID:11400.122
disease of anatomical entityDOID:700.122
musculoskeletal system diseaseDOID:1700.046
connective tissue diseaseDOID:6500.037
bone diseaseDOID:008000100.025
bone development diseaseDOID:008000600.010