IMP: Integrative Multi-species Prediction

Drosophila melanogaster

26 known processes

PCID2 (Dmel_CG7351)

PCI domain-containing protein 2

(Aliases: Dmel\CG7351,CG7351,dmPCID2)

FLYBASE: FBgn0036184
Entrez: 39306
UniProtKB: Q9VTL1

Process Predictions
Disease Predictions

PCID2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
protein modification process	GO:0036211	438	0.066
negative regulation of cellular metabolic process	GO:0031324	382	0.048	Human
organonitrogen compound metabolic process	GO:1901564	318	0.047
regulation of cell cycle	GO:0051726	291	0.047	Human
regulation of cell cycle phase transition	GO:1901987	130	0.043	Human
cellular protein modification process	GO:0006464	438	0.042
negative regulation of gene expression	GO:0010629	387	0.039	Human
nuclear division	GO:0000280	332	0.039
cell death	GO:0008219	279	0.038	Human
mitotic cell cycle phase transition	GO:0044772	138	0.037
negative regulation of cellular biosynthetic process	GO:0031327	277	0.037
chromosome organization	GO:0051276	360	0.036
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.033
negative regulation of transcription dna templated	GO:0045892	237	0.032
establishment of protein localization	GO:0045184	163	0.032
regulation of cellular protein metabolic process	GO:0032268	243	0.030	Human
regulation of cell cycle process	GO:0010564	181	0.029	Human
regulation of organelle organization	GO:0033043	196	0.028	Human
post embryonic appendage morphogenesis	GO:0035120	385	0.027
protein localization	GO:0008104	284	0.027
oxoacid metabolic process	GO:0043436	103	0.027
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.026
intracellular transport	GO:0046907	228	0.025
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.024
vesicle mediated transport	GO:0016192	381	0.023
organelle assembly	GO:0070925	198	0.023
negative regulation of cell cycle process	GO:0010948	109	0.023	Human
death	GO:0016265	284	0.023	Human
dna damage checkpoint	GO:0000077	78	0.022
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.022
transcription from rna polymerase ii promoter	GO:0006366	368	0.022
endocytosis	GO:0006897	310	0.022
catabolic process	GO:0009056	409	0.022
chromatin organization	GO:0006325	207	0.021
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.021	Human
phosphorylation	GO:0016310	294	0.021
cell cycle checkpoint	GO:0000075	95	0.021	Human
regulation of catabolic process	GO:0009894	170	0.020	Human
single organism intracellular transport	GO:1902582	207	0.020
negative regulation of rna biosynthetic process	GO:1902679	240	0.020
chemotaxis	GO:0006935	249	0.020
cellular protein localization	GO:0034613	160	0.020
mitotic nuclear division	GO:0007067	213	0.020
small molecule metabolic process	GO:0044281	305	0.020
carbohydrate derivative metabolic process	GO:1901135	217	0.020
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.019	Human
dna metabolic process	GO:0006259	227	0.019
camera type eye development	GO:0043010	4	0.019
regulation of protein metabolic process	GO:0051246	256	0.018	Human
cytoplasmic transport	GO:0016482	130	0.018
rna processing	GO:0006396	147	0.018
cell division	GO:0051301	248	0.018
negative regulation of mitotic cell cycle	GO:0045930	109	0.018	Human
heterocycle catabolic process	GO:0046700	166	0.018
dna integrity checkpoint	GO:0031570	81	0.017
organic substance transport	GO:0071702	257	0.017
cellular catabolic process	GO:0044248	372	0.017
regulation of cellular amino acid metabolic process	GO:0006521	0	0.017
nuclear transport	GO:0051169	72	0.017
cellular macromolecule localization	GO:0070727	220	0.017
negative regulation of rna metabolic process	GO:0051253	251	0.017
protein phosphorylation	GO:0006468	169	0.017
central nervous system development	GO:0007417	201	0.017
programmed cell death	GO:0012501	257	0.016	Human
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.016
imaginal disc derived appendage development	GO:0048737	399	0.016
cell cycle phase transition	GO:0044770	140	0.016
appendage development	GO:0048736	401	0.016
protein transport	GO:0015031	155	0.015
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.015	Human
eye morphogenesis	GO:0048592	260	0.015
posttranscriptional regulation of gene expression	GO:0010608	145	0.015	Human
negative regulation of cell cycle	GO:0045786	116	0.015	Human
defense response	GO:0006952	300	0.015
compound eye development	GO:0048749	307	0.015
single organism catabolic process	GO:0044712	228	0.015
positive regulation of cellular component organization	GO:0051130	156	0.015
imaginal disc derived wing morphogenesis	GO:0007476	337	0.015
organic substance catabolic process	GO:1901575	308	0.015
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.014
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.014	Human
regulation of mitotic cell cycle	GO:0007346	190	0.014	Human
positive regulation of response to stimulus	GO:0048584	323	0.014
mitotic g2 m transition checkpoint	GO:0044818	70	0.014
taxis	GO:0042330	304	0.014
cellular response to dna damage stimulus	GO:0006974	223	0.014
single organism membrane organization	GO:0044802	93	0.014
phagocytosis	GO:0006909	215	0.014
regulation of phosphate metabolic process	GO:0019220	210	0.014
negative regulation of response to stimulus	GO:0048585	258	0.014
cellular amino acid metabolic process	GO:0006520	61	0.014
organic cyclic compound catabolic process	GO:1901361	168	0.013
regulation of cell death	GO:0010941	173	0.013	Human
macromolecular complex assembly	GO:0065003	256	0.013
single organism biosynthetic process	GO:0044711	206	0.013
regulation of cell differentiation	GO:0045595	302	0.013
chromatin modification	GO:0016568	147	0.013
negative regulation of developmental process	GO:0051093	201	0.013
actin cytoskeleton organization	GO:0030036	206	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.013
mrna metabolic process	GO:0016071	124	0.012
negative regulation of cell cycle phase transition	GO:1901988	103	0.012	Human
positive regulation of transcription dna templated	GO:0045893	266	0.012	Human
regulation of hydrolase activity	GO:0051336	97	0.012	Human
amine metabolic process	GO:0009308	12	0.012
cellular amine metabolic process	GO:0044106	12	0.012
nucleoside phosphate metabolic process	GO:0006753	162	0.012
g2 dna damage checkpoint	GO:0031572	69	0.012
membrane organization	GO:0061024	112	0.012
negative regulation of biosynthetic process	GO:0009890	277	0.012
regulation of cellular amine metabolic process	GO:0033238	3	0.012
endomembrane system organization	GO:0010256	119	0.012
chromatin remodeling	GO:0006338	72	0.011
actin filament based process	GO:0030029	220	0.011
positive regulation of signaling	GO:0023056	243	0.011
stem cell differentiation	GO:0048863	117	0.011
negative regulation of signal transduction	GO:0009968	206	0.011
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.011
mitotic dna integrity checkpoint	GO:0044774	75	0.011
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.011	Human
positive regulation of molecular function	GO:0044093	136	0.011
organonitrogen compound biosynthetic process	GO:1901566	117	0.011
gene silencing	GO:0016458	138	0.011
single organism cellular localization	GO:1902580	180	0.011
response to organic substance	GO:0010033	284	0.011
growth	GO:0040007	359	0.011
regulation of cellular ketone metabolic process	GO:0010565	3	0.011
developmental growth	GO:0048589	280	0.011
purine ribonucleotide metabolic process	GO:0009150	145	0.011
response to other organism	GO:0051707	293	0.011
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.011
positive regulation of rna biosynthetic process	GO:1902680	266	0.011	Human
response to oxygen containing compound	GO:1901700	200	0.010
cellular macromolecular complex assembly	GO:0034622	153	0.010
compound eye morphogenesis	GO:0001745	249	0.010
aromatic compound catabolic process	GO:0019439	166	0.010
positive regulation of cellular component biogenesis	GO:0044089	80	0.010
nucleoside catabolic process	GO:0009164	112	0.010
regulation of cellular component biogenesis	GO:0044087	201	0.010
regulation of response to stress	GO:0080134	200	0.010
organic acid metabolic process	GO:0006082	103	0.010
regulation of apoptotic process	GO:0042981	130	0.010	Human

PCID2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.022

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