Drosophila melanogaster

167 known processes

CoRest (Dmel_CG42687)

CG42687 gene product from transcript CG42687-RC

(Aliases: CoREST,dCoREST,BcDNA:LD11215,CG42687,CG32534,CG32535,i169,Dmel_CG32534,CG3878,BcDNA:GH01486,Dmel\CG42687,CG33525,Dmel_CG33525)

CoRest biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
imaginal disc derived wing morphogenesisGO:00074763370.471
appendage morphogenesisGO:00351073970.301
response to abiotic stimulusGO:00096283410.276
post embryonic appendage morphogenesisGO:00351203850.247
appendage developmentGO:00487364010.236
cell proliferationGO:00082832990.229
endocytosisGO:00068973100.141
epithelial cell differentiationGO:00308553220.137
amine metabolic processGO:0009308120.136
gland developmentGO:00487321910.116
glycerolipid catabolic processGO:004650330.114
small molecule metabolic processGO:00442813050.113
circadian rhythmGO:00076231050.112
cell cell signaling involved in cell fate commitmentGO:00451682100.110
imaginal disc derived appendage morphogenesisGO:00351143950.107
organonitrogen compound metabolic processGO:19015643180.101
homeostatic processGO:00425921990.098
compound eye developmentGO:00487493070.097
response to temperature stimulusGO:00092661060.096
establishment or maintenance of cell polarityGO:00071631670.089
cellular amine metabolic processGO:0044106120.087
imaginal disc derived appendage developmentGO:00487373990.087
ion homeostasisGO:0050801550.086
phosphorylationGO:00163102940.079
epithelial cell developmentGO:00020642740.076
cellular amino acid metabolic processGO:0006520610.075
phagocytosisGO:00069092150.073
negative regulation of cellular metabolic processGO:00313243820.068
vesicle mediated transportGO:00161923810.068
triglyceride catabolic processGO:001943330.067
catabolic processGO:00090564090.067
ovarian follicle cell developmentGO:00307072480.064
wing disc morphogenesisGO:00074723440.062
regulation of phosphate metabolic processGO:00192202100.061
carboxylic acid metabolic processGO:0019752920.060
eye developmentGO:00016543230.059
chemical homeostasisGO:0048878920.058
sensory organ morphogenesisGO:00905962600.058
g protein coupled receptor signaling pathwayGO:00071861360.057
organophosphate catabolic processGO:00464341120.056
nuclear divisionGO:00002803320.054
regionalizationGO:00030024160.054
response to biotic stimulusGO:00096072940.053
salivary gland developmentGO:00074311620.052
tissue morphogenesisGO:00487292970.051
compound eye morphogenesisGO:00017452490.050
morphogenesis of an epitheliumGO:00020092760.050
lateral inhibitionGO:00463312060.049
organophosphate metabolic processGO:00196371950.049
cellular response to chemical stimulusGO:00708871990.047
developmental growthGO:00485892800.046
cholesterol homeostasisGO:004263230.045
eye morphogenesisGO:00485922600.045
growthGO:00400073590.044
cell projection assemblyGO:0030031940.044
localization of cellGO:00516742570.043
regulation of cell morphogenesisGO:00226041630.043
regulation of anatomical structure morphogenesisGO:00226032420.042
cellular response to radiationGO:0071478520.042
spermatid differentiationGO:00485151140.042
synaptic transmissionGO:00072682880.042
embryonic development via the syncytial blastodermGO:00017001480.041
oxoacid metabolic processGO:00434361030.041
cellular protein modification processGO:00064644380.041
developmental programmed cell deathGO:00106231380.040
enzyme linked receptor protein signaling pathwayGO:00071671790.040
open tracheal system developmentGO:00074242040.039
protein modification processGO:00362114380.039
regulation of response to stressGO:00801342000.038
single organism behaviorGO:00447083910.038
notch signaling pathwayGO:00072191200.038
regulation of cell developmentGO:00602842150.038
regulation of phosphorus metabolic processGO:00511742100.038
cell migrationGO:00164772380.038
negative regulation of response to stimulusGO:00485852580.037
regulation of protein metabolic processGO:00512462560.037
mitotic cell cycle phase transitionGO:00447721380.037
rna localizationGO:00064031150.036
anterior posterior axis specificationGO:00099481090.035
developmental maturationGO:00217001720.035
chromosome organizationGO:00512763600.034
regulation of synapse structure and activityGO:00508031280.034
regulation of localizationGO:00328792750.034
embryonic morphogenesisGO:00485982060.034
response to radiationGO:00093141550.034
response to hypoxiaGO:0001666530.034
regulation of nervous system developmentGO:00519602480.033
asymmetric protein localizationGO:0008105330.033
neurological system processGO:00508773580.033
negative regulation of cellular component organizationGO:00511291080.033
mitotic nuclear divisionGO:00070672130.033
organic substance catabolic processGO:19015753080.033
segmentationGO:00352822070.033
negative regulation of rna metabolic processGO:00512532510.032
embryonic pattern specificationGO:00098801740.032
negative regulation of signal transductionGO:00099682060.032
regulation of cellular protein metabolic processGO:00322682430.032
histone modificationGO:00165701060.032
phosphatidylethanolamine metabolic processGO:004633710.032
columnar cuboidal epithelial cell differentiationGO:00020652560.032
defense response to other organismGO:00985422250.031
histolysisGO:00075591020.031
positive regulation of response to stimulusGO:00485843230.031
oocyte developmentGO:00485991240.031
negative regulation of signalingGO:00230572190.031
regulation of intracellular signal transductionGO:19025312360.031
mrna metabolic processGO:00160711240.030
cellular amide metabolic processGO:0043603800.030
autophagic cell deathGO:0048102830.030
negative regulation of cellular biosynthetic processGO:00313272770.030
cholesterol transportGO:003030120.029
carbohydrate derivative metabolic processGO:19011352170.029
protein complex biogenesisGO:00702712010.029
negative regulation of cell communicationGO:00106482230.028
regulation of transportGO:00510491810.028
response to other organismGO:00517072930.028
spindle organizationGO:00070512530.028
single organism catabolic processGO:00447122280.028
intracellular signal transductionGO:00355563000.028
regulation of cell divisionGO:0051302720.028
ethanolamine containing compound metabolic processGO:004243940.028
cell deathGO:00082192790.028
regulation of notch signaling pathwayGO:00085931000.028
cellular catabolic processGO:00442483720.027
nucleotide metabolic processGO:00091171610.027
oocyte differentiationGO:00099941450.027
rhythmic processGO:00485111060.027
single organism cellular localizationGO:19025801800.027
regulation of cholesterol transportGO:003237410.027
cell maturationGO:00484691440.027
deathGO:00162652840.026
negative regulation of nervous system developmentGO:0051961920.026
acylglycerol catabolic processGO:004646430.026
cilium organizationGO:0044782410.026
regulation of immune responseGO:00507761180.026
immune responseGO:00069552460.026
salivary gland histolysisGO:0035070880.026
blastoderm segmentationGO:00073501590.026
regulation of cell cycleGO:00517262910.026
photoreceptor cell differentiationGO:00465301700.026
cellular response to endogenous stimulusGO:0071495800.026
reproductive structure developmentGO:0048608740.026
regulation of molecular functionGO:00650092170.025
memoryGO:0007613940.025
gland morphogenesisGO:00226121450.025
cellular biogenic amine metabolic processGO:000657690.025
regulation of phosphorylationGO:00423251470.025
positive regulation of multicellular organismal processGO:00512401430.025
regulation of cell cycle phase transitionGO:19019871300.025
axon developmentGO:00615642970.025
response to external biotic stimulusGO:00432072930.025
morphogenesis of follicular epitheliumGO:0016333360.025
oocyte axis specificationGO:00073091080.025
tissue deathGO:00162711020.025
columnar cuboidal epithelial cell developmentGO:00020662490.024
ovarian follicle cell migrationGO:00072971210.024
negative regulation of mitotic cell cycleGO:00459301090.024
camera type eye developmentGO:004301040.023
defense response to gram negative bacteriumGO:0050829940.023
retina development in camera type eyeGO:006004140.023
cellular protein catabolic processGO:0044257830.023
kidney developmentGO:000182230.023
response to decreased oxygen levelsGO:0036293580.023
cellular response to abiotic stimulusGO:0071214580.023
anatomical structure homeostasisGO:0060249970.023
tissue migrationGO:00901301550.023
embryo development ending in birth or egg hatchingGO:00097921520.023
regulation of cellular amine metabolic processGO:003323830.023
protein phosphorylationGO:00064681690.023
regulation of immune system processGO:00026821760.022
oocyte constructionGO:00073081120.022
negative regulation of macromolecule biosynthetic processGO:00105582700.022
neutral lipid catabolic processGO:004646130.022
cilium morphogenesisGO:0060271390.022
phosphatidic acid metabolic processGO:004647310.022
regulation of catalytic activityGO:00507901850.022
positive regulation of signalingGO:00230562430.022
regulation of cellular amino acid metabolic processGO:000652100.022
organic substance transportGO:00717022570.022
positive regulation of cellular component organizationGO:00511301560.022
establishment of localization in cellGO:00516494020.022
nucleoside phosphate metabolic processGO:00067531620.022
cellular ketone metabolic processGO:0042180240.021
establishment of cell polarityGO:0030010400.021
defense responseGO:00069523000.021
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
macromolecular complex assemblyGO:00650032560.021
adult behaviorGO:00305341370.021
tube morphogenesisGO:00352391910.021
cuticle developmentGO:0042335860.021
negative regulation of intracellular signal transductionGO:1902532570.020
regulation of mapk cascadeGO:0043408920.020
response to endogenous stimulusGO:00097191190.020
proteolysis involved in cellular protein catabolic processGO:0051603830.020
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.020
border follicle cell migrationGO:00072981130.020
sulfur compound biosynthetic processGO:0044272160.020
chromosome segregationGO:00070591570.020
maintenance of locationGO:0051235730.020
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.020
locomotory behaviorGO:00076261760.020
positive regulation of lipid storageGO:001088440.020
mitotic dna damage checkpointGO:0044773740.020
salivary gland cell autophagic cell deathGO:0035071830.020
cell junction organizationGO:0034330570.019
defense response to bacteriumGO:00427421780.019
tube developmentGO:00352952440.019
cellular macromolecule catabolic processGO:00442651360.019
cell adhesionGO:00071551360.019
chemosensory behaviorGO:00076351060.019
somatic stem cell divisionGO:0048103370.019
male gamete generationGO:00482322010.019
regulation of defense responseGO:00313471020.019
protein complex assemblyGO:00064612000.018
programmed cell deathGO:00125012570.018
cell motilityGO:00488702510.018
positive regulation of cellular biosynthetic processGO:00313283160.018
mitotic cell cycle checkpointGO:0007093880.018
proteasomal protein catabolic processGO:0010498590.018
cytoplasmic transportGO:00164821300.018
regulation of sister chromatid segregationGO:0033045280.018
cell divisionGO:00513012480.018
imaginal disc pattern formationGO:0007447910.018
exocrine system developmentGO:00352721620.018
immune system processGO:00023763470.018
negative regulation of cell developmentGO:0010721620.018
regulation of innate immune responseGO:0045088710.018
establishment or maintenance of bipolar cell polarityGO:0061245340.017
synapse organizationGO:00508081960.017
digestive tract morphogenesisGO:00485461270.017
stem cell divisionGO:0017145690.017
salivary gland morphogenesisGO:00074351450.017
regulation of cell proliferationGO:00421271630.017
proteolysisGO:00065081920.017
positive regulation of phosphate metabolic processGO:00459371390.017
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.017
regulation of developmental growthGO:00486381740.017
positive regulation of immune responseGO:0050778630.017
dephosphorylationGO:0016311510.017
ameboidal type cell migrationGO:00016671510.017
chemotaxisGO:00069352490.017
organic acid metabolic processGO:00060821030.017
response to inorganic substanceGO:0010035440.017
establishment or maintenance of apical basal cell polarityGO:0035088340.017
female germ line cyst formationGO:0048135420.017
developmental growth involved in morphogenesisGO:0060560650.017
response to organonitrogen compoundGO:0010243750.017
regulation of organ morphogenesisGO:2000027780.017
response to acid chemicalGO:0001101250.016
cell cycle phase transitionGO:00447701400.016
negative regulation of cell differentiationGO:00455961430.016
cell cell junction organizationGO:0045216550.016
positive regulation of cellular amino acid metabolic processGO:004576400.016
negative regulation of erk1 and erk2 cascadeGO:007037330.016
germ line cyst formationGO:0048134440.016
cation transportGO:00068121100.016
negative regulation of cellular protein metabolic processGO:0032269850.016
positive regulation of transcription dna templatedGO:00458932660.016
negative regulation of cell cycleGO:00457861160.016
actin filament organizationGO:00070151260.016
asymmetric stem cell divisionGO:0098722490.016
multicellular organismal agingGO:00102591400.016
response to lipopolysaccharideGO:003249640.016
negative regulation of cell cycle phase transitionGO:19019881030.016
positive regulation of molecular functionGO:00440931360.015
regulation of protein phosphorylationGO:0001932640.015
neuron projection guidanceGO:00974852410.015
regulation of cell deathGO:00109411730.015
single organism intracellular transportGO:19025822070.015
taxisGO:00423303040.015
multicellular organismal homeostasisGO:0048871410.015
detection of stimulus involved in sensory perceptionGO:0050906920.015
regulation of cell differentiationGO:00455953020.015
ion transportGO:00068111450.015
mitotic sister chromatid segregationGO:0000070870.015
regulation of neurogenesisGO:00507671580.015
respiratory system developmentGO:00605412130.015
peptidyl amino acid modificationGO:00181931050.015
triglyceride homeostasisGO:0070328180.015
regulation of small gtpase mediated signal transductionGO:0051056930.015
cellular response to organic substanceGO:00713101320.015
cation homeostasisGO:0055080510.015
positive regulation of cellular amine metabolic processGO:003324000.015
detection of stimulusGO:00516061560.015
single organism biosynthetic processGO:00447112060.015
germarium derived egg chamber formationGO:00072931010.015
lipid localizationGO:0010876540.015
protein transportGO:00150311550.015
sterol homeostasisGO:005509240.015
negative regulation of multicellular organismal processGO:00512411420.015
negative regulation of developmental processGO:00510932010.015
peptide metabolic processGO:0006518800.015
modification dependent macromolecule catabolic processGO:0043632790.015
response to organic cyclic compoundGO:0014070890.015
modification dependent protein catabolic processGO:0019941780.014
axis specificationGO:00097981670.014
carbohydrate derivative biosynthetic processGO:1901137850.014
positive regulation of sequestering of triglycerideGO:001089010.014
mitotic spindle organizationGO:00070522200.014
phosphatidylcholine metabolic processGO:004647030.014
cellular homeostasisGO:0019725800.014
pole plasm oskar mrna localizationGO:0045451460.014
response to oxygen containing compoundGO:19017002000.014
ubiquitin dependent protein catabolic processGO:0006511780.014
neuroblast proliferationGO:0007405740.014
dorsal ventral pattern formationGO:00099531330.014
mitotic dna integrity checkpointGO:0044774750.014
chromosome separationGO:0051304420.014
negative regulation of transcription dna templatedGO:00458922370.014
regulation of cell shapeGO:00083601130.014
hair cell differentiationGO:0035315470.014
establishment of planar polarityGO:0001736870.014
regulation of mitotic cell cycleGO:00073461900.014
positive regulation of catabolic processGO:00098961050.014
protein maturationGO:0051604710.014
negative regulation of mitotic cell cycle phase transitionGO:19019911030.014
morphogenesis of a polarized epitheliumGO:0001738930.014
regulation of cell projection organizationGO:0031344920.014
response to organic substanceGO:00100332840.014
cellular ion homeostasisGO:0006873390.014
spermatogenesisGO:00072832000.013
regulation of cellular response to stressGO:0080135890.013
phototransductionGO:0007602520.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
mapk cascadeGO:00001651070.013
negative regulation of phosphate metabolic processGO:0045936450.013
negative regulation of cell deathGO:0060548810.013
regulation of synapse organizationGO:00508071100.013
glycoprotein biosynthetic processGO:0009101410.013
erbb signaling pathwayGO:0038127580.013
response to oxygen levelsGO:0070482590.013
ras protein signal transductionGO:0007265880.013
transcription from rna polymerase ii promoterGO:00063663680.013
aromatic compound catabolic processGO:00194391660.013
regulation of meiosisGO:004002030.013
negative regulation of biosynthetic processGO:00098902770.013
positive regulation of phosphorus metabolic processGO:00105621390.013
sex differentiationGO:0007548810.013
regulation of growthGO:00400082330.013
immune response activating signal transductionGO:000275720.013
mrna processingGO:00063971040.013
protein catabolic processGO:00301631010.013
camera type eye morphogenesisGO:004859320.013
immune effector processGO:0002252980.013
cellular modified amino acid metabolic processGO:0006575450.013
purine containing compound metabolic processGO:00725211550.013
regulation of cellular component sizeGO:0032535980.013
cellular component assembly involved in morphogenesisGO:00109271510.013
chromatin modificationGO:00165681470.013
morphogenesis of embryonic epitheliumGO:0016331940.013
positive regulation of protein modification processGO:0031401580.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
feeding behaviorGO:0007631500.013
regulation of protein catabolic processGO:0042176550.013
regulation of embryonic cell shapeGO:0016476300.012
chaeta developmentGO:0022416970.012
nucleocytoplasmic transportGO:0006913720.012
skin developmentGO:0043588650.012
endodermal cell differentiationGO:003598730.012
asymmetric neuroblast divisionGO:0055059330.012
regulation of synaptic transmissionGO:0050804690.012
neuronal stem cell divisionGO:0036445350.012
response to bacteriumGO:00096171980.012
response to virusGO:0009615280.012
endomembrane system organizationGO:00102561190.012
regulation of cytokinesisGO:003246530.012
small gtpase mediated signal transductionGO:0007264880.012
regulation of neuron differentiationGO:00456641030.012
gastrulationGO:0007369700.012
sensory perception of painGO:001923340.012
response to alcoholGO:0097305950.012
dorsal ventral axis specificationGO:0009950660.012
oocyte anterior posterior axis specificationGO:0007314720.012
response to calcium ionGO:005159210.012
digestive system developmentGO:00551231490.012
cytoskeleton dependent cytokinesisGO:0061640810.012
maternal determination of anterior posterior axis embryoGO:0008358740.012
establishment of tissue polarityGO:0007164870.011
negative regulation of protein metabolic processGO:0051248850.011
response to peptideGO:1901652290.011
negative regulation of neurogenesisGO:0050768530.011
embryonic axis specificationGO:00005781070.011
regulation of erbb signaling pathwayGO:1901184420.011
regulation of mitotic cell cycle phase transitionGO:19019901300.011
positive regulation of protein metabolic processGO:00512471280.011
positive regulation of cell communicationGO:00106472500.011
regulation of response to external stimulusGO:00321011150.011
positive regulation of catalytic activityGO:00430851180.011
chromatin organizationGO:00063252070.011
positive regulation of macromolecule biosynthetic processGO:00105572830.011
intracellular transportGO:00469072280.011
neuromuscular junction developmentGO:00075281490.011
purine ribonucleotide metabolic processGO:00091501450.011
response to nutrient levelsGO:00316671140.011
regulation of i kappab kinase nf kappab signalingGO:004312220.011
mrna splicing via spliceosomeGO:0000398730.011
cation transmembrane transportGO:0098655880.011
regulation of organelle organizationGO:00330431960.011
positive regulation of phosphorylationGO:0042327870.011
regulation of ras protein signal transductionGO:0046578930.011
regulation of cell morphogenesis involved in differentiationGO:0010769610.011
regulation of intracellular protein transportGO:0033157460.011
epithelial cell migrationGO:00106311480.011
epidermal growth factor receptor signaling pathwayGO:0007173580.011
regulation of protein kinase activityGO:0045859510.011
development of primary sexual characteristicsGO:0045137500.011
response to nitrogen compoundGO:1901698900.010
sensory perceptionGO:00076001960.010
regulation of lipid transportGO:003236830.010
regulation of cellular component biogenesisGO:00440872010.010
positive regulation of rna biosynthetic processGO:19026802660.010
synaptic growth at neuromuscular junctionGO:00511241190.010
regulation of peptidase activityGO:0052547390.010
spermatid developmentGO:0007286980.010
regulation of tube architecture open tracheal systemGO:0035152680.010
spinal cord developmentGO:002151010.010
organophosphate biosynthetic processGO:0090407460.010
anterior posterior axis specification embryoGO:00085951030.010
regulation of cellular ketone metabolic processGO:001056530.010
pole plasm mrna localizationGO:0019094490.010
pole plasm assemblyGO:0007315610.010
negative regulation of developmental growthGO:0048640640.010
negative regulation of nitrogen compound metabolic processGO:00511722650.010
positive regulation of defense responseGO:0031349590.010
macromolecule catabolic processGO:00090571610.010
cellular cation homeostasisGO:0030003380.010
regulation of proteolysisGO:0030162870.010
mitotic cytokinesisGO:0000281500.010
apoptotic processGO:00069151590.010

CoRest disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.205
hair diseaseDOID:42100.168
integumentary system diseaseDOID:1600.168
lipid metabolism disorderDOID:314600.092
familial hyperlipidemiaDOID:116800.092
disease of metabolismDOID:001466700.092
familial combined hyperlipidemiaDOID:1380900.092
inherited metabolic disorderDOID:65500.092
nervous system diseaseDOID:86300.017
organ system cancerDOID:005068600.015
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
urinary system diseaseDOID:1800.011
kidney diseaseDOID:55700.011