Drosophila melanogaster

42 known processes

Lig4 (Dmel_CG12176)

Ligase4

(Aliases: lig4,RE37186,CG12176,Dmel\CG12176)

Lig4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna metabolic processGO:00062592270.723
dna repairGO:0006281540.480
telomere organizationGO:0032200210.394
chromosome organizationGO:00512763600.268
double strand break repair via nonhomologous end joiningGO:000630350.224
cellular catabolic processGO:00442483720.201
purine nucleotide metabolic processGO:00061631460.161
nucleobase containing compound catabolic processGO:00346551650.160
nucleoside triphosphate metabolic processGO:00091411200.151
double strand break repairGO:0006302260.148
carbohydrate derivative metabolic processGO:19011352170.133
catabolic processGO:00090564090.126
purine nucleoside triphosphate metabolic processGO:00091441190.124
response to abiotic stimulusGO:00096283410.124
ribonucleoside triphosphate catabolic processGO:00092031080.114
organophosphate metabolic processGO:00196371950.109
heterocycle catabolic processGO:00467001660.107
regionalizationGO:00030024160.097
ribonucleoside triphosphate metabolic processGO:00091991190.095
nucleoside catabolic processGO:00091641120.093
organic cyclic compound catabolic processGO:19013611680.092
ribonucleotide metabolic processGO:00092591450.091
purine containing compound metabolic processGO:00725211550.091
purine nucleoside catabolic processGO:00061521120.091
cellular response to dna damage stimulusGO:00069742230.091
nucleoside monophosphate metabolic processGO:0009123520.090
chromatin organizationGO:00063252070.089
purine ribonucleoside monophosphate metabolic processGO:0009167500.083
negative regulation of cellular metabolic processGO:00313243820.082
ribonucleoside catabolic processGO:00424541120.081
glycosyl compound metabolic processGO:19016571270.081
negative regulation of nitrogen compound metabolic processGO:00511722650.079
organonitrogen compound metabolic processGO:19015643180.078
response to radiationGO:00093141550.076
aromatic compound catabolic processGO:00194391660.075
purine nucleoside monophosphate metabolic processGO:0009126500.074
nucleobase containing small molecule metabolic processGO:00550861740.073
nucleoside phosphate metabolic processGO:00067531620.073
positive regulation of nitrogen compound metabolic processGO:00511733540.073
organic substance catabolic processGO:19015753080.072
purine ribonucleoside metabolic processGO:00461281270.072
negative regulation of nucleobase containing compound metabolic processGO:00459342610.071
nucleoside metabolic processGO:00091161270.071
purine ribonucleotide metabolic processGO:00091501450.070
ribonucleoside metabolic processGO:00091191270.069
purine nucleotide catabolic processGO:00061951090.068
purine ribonucleotide catabolic processGO:00091541090.068
purine ribonucleoside catabolic processGO:00461301120.066
purine ribonucleoside triphosphate catabolic processGO:00092071080.066
carbohydrate derivative catabolic processGO:19011361180.065
ribonucleotide catabolic processGO:00092611090.064
purine containing compound catabolic processGO:00725231120.062
purine nucleoside triphosphate catabolic processGO:00091461080.061
cellular nitrogen compound catabolic processGO:00442701650.060
purine ribonucleoside triphosphate metabolic processGO:00092051190.059
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.058
nucleotide catabolic processGO:00091661090.058
nucleoside triphosphate catabolic processGO:00091431080.058
atp metabolic processGO:0046034490.057
small molecule metabolic processGO:00442813050.053
ribose phosphate metabolic processGO:00196931450.051
anterior posterior pattern specificationGO:00099521360.050
vesicle mediated transportGO:00161923810.048
mitotic g2 m transition checkpointGO:0044818700.047
purine nucleoside metabolic processGO:00422781270.047
organophosphate catabolic processGO:00464341120.046
nucleoside phosphate catabolic processGO:19012921100.045
organonitrogen compound catabolic processGO:19015651280.045
cellular component assembly involved in morphogenesisGO:00109271510.045
cellular macromolecule localizationGO:00707272200.044
single organism biosynthetic processGO:00447112060.044
ribonucleoside monophosphate metabolic processGO:0009161510.040
telomere maintenanceGO:0000723210.039
cellular response to radiationGO:0071478520.039
small gtpase mediated signal transductionGO:0007264880.039
negative regulation of gene expressionGO:00106293870.039
negative regulation of cellular biosynthetic processGO:00313272770.038
anatomical structure homeostasisGO:0060249970.038
immune system processGO:00023763470.036
endocytosisGO:00068973100.035
regulation of intracellular signal transductionGO:19025312360.035
nucleotide metabolic processGO:00091171610.034
positive regulation of nucleobase containing compound metabolic processGO:00459353320.033
regulation of response to stressGO:00801342000.033
chromatin remodelingGO:0006338720.033
intracellular transportGO:00469072280.032
ribonucleoside monophosphate catabolic processGO:0009158390.032
cellular protein modification processGO:00064644380.032
negative regulation of biosynthetic processGO:00098902770.031
signal transduction by phosphorylationGO:00230141070.030
purine nucleoside monophosphate catabolic processGO:0009128380.030
atp catabolic processGO:0006200380.029
nuclear divisionGO:00002803320.029
ras protein signal transductionGO:0007265880.028
regulation of ras protein signal transductionGO:0046578930.028
anterior posterior axis specificationGO:00099481090.027
female meiotic divisionGO:0007143700.027
axis specificationGO:00097981670.027
intracellular mrna localizationGO:0008298660.027
dna biosynthetic processGO:0071897240.026
protein localizationGO:00081042840.026
regulation of phosphate metabolic processGO:00192202100.026
male gamete generationGO:00482322010.026
positive regulation of phosphorus metabolic processGO:00105621390.025
immune responseGO:00069552460.025
chromosome segregationGO:00070591570.025
organelle fissionGO:00482853400.024
response to ionizing radiationGO:0010212320.024
intracellular signal transductionGO:00355563000.024
macromolecular complex assemblyGO:00650032560.023
response to light stimulusGO:00094161240.023
regulation of mitotic cell cycleGO:00073461900.023
negative regulation of macromolecule biosynthetic processGO:00105582700.023
positive regulation of multicellular organismal processGO:00512401430.023
gene silencingGO:00164581380.022
defense response to other organismGO:00985422250.022
regulation of cellular ketone metabolic processGO:001056530.022
regulation of localizationGO:00328792750.022
protein complex assemblyGO:00064612000.022
macromolecule catabolic processGO:00090571610.022
regulation of molecular functionGO:00650092170.021
cellular protein localizationGO:00346131600.021
non recombinational repairGO:000072670.021
protein modification processGO:00362114380.021
cellular macromolecule catabolic processGO:00442651360.021
meiotic nuclear divisionGO:00071261510.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
regulation of small gtpase mediated signal transductionGO:0051056930.021
developmental maturationGO:00217001720.020
proteolysisGO:00065081920.020
blastoderm segmentationGO:00073501590.020
dorsal ventral pattern formationGO:00099531330.020
cellular macromolecular complex assemblyGO:00346221530.020
glycosyl compound catabolic processGO:19016581120.020
regulation of gene expression epigeneticGO:00400291280.019
immune system developmentGO:0002520570.019
postreplication repairGO:000630120.019
regulation of mitotic cell cycle phase transitionGO:19019901300.019
cell cycle phase transitionGO:00447701400.019
oocyte differentiationGO:00099941450.019
single organism catabolic processGO:00447122280.019
positive regulation of molecular functionGO:00440931360.019
protein complex biogenesisGO:00702712010.019
imaginal disc derived wing morphogenesisGO:00074763370.019
cellular response to ionizing radiationGO:0071479150.018
response to other organismGO:00517072930.018
positive regulation of macromolecule metabolic processGO:00106044050.018
negative regulation of nucleic acid templated transcriptionGO:19035072400.018
defense responseGO:00069523000.018
transcription from rna polymerase ii promoterGO:00063663680.018
forebrain developmentGO:003090020.018
positive regulation of apoptotic signaling pathwayGO:200123540.018
nucleoside monophosphate catabolic processGO:0009125390.018
response to bacteriumGO:00096171980.018
positive regulation of nucleotide catabolic processGO:0030813460.018
positive regulation of nucleic acid templated transcriptionGO:19035082660.018
regulation of hydrolase activityGO:0051336970.017
response to organic substanceGO:00100332840.017
anterior posterior axis specification embryoGO:00085951030.017
spermatogenesisGO:00072832000.017
chromatin assembly or disassemblyGO:0006333520.017
appendage developmentGO:00487364010.017
single organism cellular localizationGO:19025801800.017
chromatin modificationGO:00165681470.017
single organism intracellular transportGO:19025822070.017
deathGO:00162652840.016
positive regulation of rna biosynthetic processGO:19026802660.016
cytoplasmic transportGO:00164821300.016
compound eye developmentGO:00487493070.016
translesion synthesisGO:001998520.016
tripartite regional subdivisionGO:00073511030.016
meiotic cell cycleGO:00513211710.016
amine metabolic processGO:0009308120.016
epithelial cell differentiationGO:00308553220.016
tissue migrationGO:00901301550.016
regulation of synapse structure and activityGO:00508031280.016
positive regulation of response to stimulusGO:00485843230.016
multi organism behaviorGO:00517051750.016
negative regulation of transcription dna templatedGO:00458922370.015
segmentationGO:00352822070.015
g2 dna damage checkpointGO:0031572690.015
chromatin silencingGO:0006342760.015
cellular response to abiotic stimulusGO:0071214580.015
negative regulation of response to stimulusGO:00485852580.015
metal ion transportGO:0030001740.015
regulation of catalytic activityGO:00507901850.015
homeostatic processGO:00425921990.015
mitotic dna integrity checkpointGO:0044774750.015
protein transportGO:00150311550.014
protein processingGO:0016485680.014
protein catabolic processGO:00301631010.014
neurological system processGO:00508773580.014
compound eye photoreceptor cell differentiationGO:00017511400.014
taxisGO:00423303040.014
response to external biotic stimulusGO:00432072930.014
positive regulation of ras gtpase activityGO:0032320360.014
regulation of catabolic processGO:00098941700.014
ameboidal type cell migrationGO:00016671510.014
regulation of cellular amino acid metabolic processGO:000652100.014
regulation of transportGO:00510491810.014
meiotic cell cycle processGO:19030461320.014
positive regulation of biosynthetic processGO:00098913160.013
innate immune responseGO:00450871440.013
axonogenesisGO:00074092900.013
positive regulation of cell migrationGO:003033520.013
immune effector processGO:0002252980.013
axon developmentGO:00615642970.013
regulation of phosphorus metabolic processGO:00511742100.013
maternal determination of anterior posterior axis embryoGO:0008358740.013
response to lipopolysaccharideGO:003249640.013
hemopoiesisGO:0030097460.013
mitotic g2 dna damage checkpointGO:0007095690.013
positive regulation of rna metabolic processGO:00512542710.013
protein modification by small protein conjugationGO:0032446790.013
cell cycle checkpointGO:0000075950.013
regulation of cell differentiationGO:00455953020.013
positive regulation of purine nucleotide catabolic processGO:0033123460.013
establishment of protein localizationGO:00451841630.013
telencephalon developmentGO:002153720.013
wing disc morphogenesisGO:00074723440.012
positive regulation of cellular amine metabolic processGO:003324000.012
regulation of nervous system developmentGO:00519602480.012
response to oxygen containing compoundGO:19017002000.012
rna localizationGO:00064031150.012
regulation of cellular localizationGO:00603411360.012
cellular homeostasisGO:0019725800.012
regulation of cell cycleGO:00517262910.012
cell motilityGO:00488702510.012
dna damage checkpointGO:0000077780.012
regulation of dna recombinationGO:000001840.012
lateral inhibitionGO:00463312060.012
regulation of response to external stimulusGO:00321011150.012
positive regulation of developmental processGO:00510941430.012
phagocytosisGO:00069092150.012
eye developmentGO:00016543230.012
regulation of chromosome organizationGO:0033044640.012
ocellus pigment metabolic processGO:0046158190.012
embryonic axis specificationGO:00005781070.011
positive regulation of cellular biosynthetic processGO:00313283160.011
regulation of cellular response to stressGO:0080135890.011
positive regulation of signalingGO:00230562430.011
positive regulation of transportGO:0051050920.011
histone modificationGO:00165701060.011
cellular protein complex assemblyGO:0043623710.011
negative regulation of mitotic cell cycle phase transitionGO:19019911030.011
positive regulation of hydrolase activityGO:0051345780.011
appendage morphogenesisGO:00351073970.011
protein dna complex subunit organizationGO:0071824860.011
positive regulation of catabolic processGO:00098961050.011
positive regulation of catalytic activityGO:00430851180.011
epithelial cell developmentGO:00020642740.011
regulation of transcription from rna polymerase ii promoterGO:00063573780.011
negative regulation of cell deathGO:0060548810.011
regulation of response to dna damage stimulusGO:2001020230.011
dna integrity checkpointGO:0031570810.011
locomotory behaviorGO:00076261760.011
positive regulation of signal transductionGO:00099672230.011
germarium derived egg chamber formationGO:00072931010.011
regulation of ras gtpase activityGO:0032318380.011
positive regulation of phosphate metabolic processGO:00459371390.011
axon guidanceGO:00074112330.011
regulation of cellular protein metabolic processGO:00322682430.011
regulation of establishment of protein localizationGO:0070201610.011
body morphogenesisGO:001017120.011
positive regulation of cellular catabolic processGO:0031331950.011
signal transduction in response to dna damageGO:004277030.011
ovarian follicle cell developmentGO:00307072480.011
pigment metabolic process involved in developmental pigmentationGO:0043324330.011
positive regulation of cell motilityGO:200014730.011
positive regulation of gene expressionGO:00106282900.011
reproductive system developmentGO:0061458740.010
mapk cascadeGO:00001651070.010
regulation of nucleotide metabolic processGO:0006140620.010
cellular amine metabolic processGO:0044106120.010
negative regulation of rna metabolic processGO:00512532510.010
regulation of gtp catabolic processGO:0033124440.010
regulation of phosphorylationGO:00423251470.010
regulation of nucleoside metabolic processGO:0009118500.010
protein localization to organelleGO:0033365820.010
phosphorylationGO:00163102940.010
developmental growthGO:00485892800.010
meiosis iGO:0007127590.010

Lig4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.018
disease of cellular proliferationDOID:1456600.017
sensory system diseaseDOID:005015500.015
nervous system diseaseDOID:86300.015
cancerDOID:16200.013