IMP: Integrative Multi-species Prediction

Drosophila melanogaster

12 known processes

nocte (Dmel_CG17255)

no circadian temperature entrainment

(Aliases: Dmel\CG17255,CG17255)

Entrez: 31976
FLYBASE: FBgn0261710
UniProtKB: Q9W2U7
UniProtKB: M9PE74

Process Predictions
Disease Predictions

nocte biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
locomotor rhythm	GO:0045475	56	0.751
circadian behavior	GO:0048512	76	0.697
rhythmic process	GO:0048511	106	0.637
circadian rhythm	GO:0007623	105	0.529
rhythmic behavior	GO:0007622	76	0.421
positive regulation of rna metabolic process	GO:0051254	271	0.149
spindle elongation	GO:0051231	83	0.143
dendrite morphogenesis	GO:0048813	199	0.125
negative regulation of gene expression	GO:0010629	387	0.113
locomotory behavior	GO:0007626	176	0.109
nuclear division	GO:0000280	332	0.105
positive regulation of macromolecule metabolic process	GO:0010604	405	0.104
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.100
organic substance catabolic process	GO:1901575	308	0.099
positive regulation of transcription dna templated	GO:0045893	266	0.097
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.091
negative regulation of rna biosynthetic process	GO:1902679	240	0.088
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.083
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.081
positive regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043280	23	0.081
positive regulation of endopeptidase activity	GO:0010950	26	0.077
positive regulation of rna biosynthetic process	GO:1902680	266	0.074
negative regulation of rna metabolic process	GO:0051253	251	0.071
mitotic spindle elongation	GO:0000022	81	0.070
positive regulation of cellular biosynthetic process	GO:0031328	316	0.069
posttranscriptional regulation of gene expression	GO:0010608	145	0.069
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.068
regulation of protein metabolic process	GO:0051246	256	0.065
organelle fission	GO:0048285	340	0.064
negative regulation of signaling	GO:0023057	219	0.064
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.063
compound eye development	GO:0048749	307	0.061
regulation of cellular protein metabolic process	GO:0032268	243	0.059
negative regulation of translation	GO:0017148	28	0.056
single organism behavior	GO:0044708	391	0.056
developmental growth	GO:0048589	280	0.054
catabolic process	GO:0009056	409	0.054
dendrite development	GO:0016358	204	0.053
positive regulation of biosynthetic process	GO:0009891	316	0.052
proteolysis	GO:0006508	192	0.052
regulation of mitotic cell cycle	GO:0007346	190	0.051
negative regulation of cell communication	GO:0010648	223	0.051
regulation of hydrolase activity	GO:0051336	97	0.050
small molecule metabolic process	GO:0044281	305	0.049
mrna processing	GO:0006397	104	0.049
cellular response to dna damage stimulus	GO:0006974	223	0.049
posttranscriptional gene silencing by rna	GO:0035194	45	0.048
regulation of endopeptidase activity	GO:0052548	36	0.047
regulation of translation	GO:0006417	56	0.047
intracellular transport	GO:0046907	228	0.046
translation	GO:0006412	69	0.046
mitotic spindle organization	GO:0007052	220	0.045
mitotic nuclear division	GO:0007067	213	0.045
establishment of localization in cell	GO:0051649	402	0.045
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	16	0.044
multicellular organismal aging	GO:0010259	140	0.043
positive regulation of cell death	GO:0010942	69	0.043
oocyte construction	GO:0007308	112	0.042
nuclear import	GO:0051170	51	0.042
regulation of mrna splicing via spliceosome	GO:0048024	64	0.041
macromolecule catabolic process	GO:0009057	161	0.040
regulation of apoptotic process	GO:0042981	130	0.039
gene silencing	GO:0016458	138	0.039
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.039
gene silencing by rna	GO:0031047	57	0.039
multi organism reproductive behavior	GO:0044705	121	0.039
transcription from rna polymerase ii promoter	GO:0006366	368	0.039
cytoplasmic transport	GO:0016482	130	0.038
compound eye morphogenesis	GO:0001745	249	0.038
organic substance transport	GO:0071702	257	0.038
dna integrity checkpoint	GO:0031570	81	0.038
regulation of catalytic activity	GO:0050790	185	0.038
cellular macromolecule localization	GO:0070727	220	0.038
nucleobase containing compound catabolic process	GO:0034655	165	0.038
negative regulation of cellular protein metabolic process	GO:0032269	85	0.037
regulation of anatomical structure size	GO:0090066	163	0.036
positive regulation of gene expression	GO:0010628	290	0.035
positive regulation of peptidase activity	GO:0010952	29	0.035
death	GO:0016265	284	0.034
carbohydrate derivative metabolic process	GO:1901135	217	0.033
salivary gland development	GO:0007431	162	0.032
regulation of gene expression epigenetic	GO:0040029	128	0.032
negative regulation of protein metabolic process	GO:0051248	85	0.031
rna interference	GO:0016246	27	0.031
blastoderm segmentation	GO:0007350	159	0.031
cell death	GO:0008219	279	0.031
cellular catabolic process	GO:0044248	372	0.030
response to other organism	GO:0051707	293	0.030
regulation of proteolysis	GO:0030162	87	0.030
spindle organization	GO:0007051	253	0.030
translational initiation	GO:0006413	11	0.029
posttranscriptional gene silencing	GO:0016441	46	0.029
positive regulation of proteolysis	GO:0045862	52	0.028
positive regulation of response to stimulus	GO:0048584	323	0.028
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.028
regulation of molecular function	GO:0065009	217	0.028
cell cycle phase transition	GO:0044770	140	0.028
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.028
cellular protein modification process	GO:0006464	438	0.027
centrosome cycle	GO:0007098	137	0.027
regulation of response to stress	GO:0080134	200	0.027
zymogen activation	GO:0031638	20	0.026
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.026
regulation of cell cycle	GO:0051726	291	0.026
imaginal disc derived appendage development	GO:0048737	399	0.025
immune system process	GO:0002376	347	0.024
gene silencing by mirna	GO:0035195	22	0.024
regulation of cysteine type endopeptidase activity	GO:2000116	27	0.024
developmental programmed cell death	GO:0010623	138	0.024
carboxylic acid metabolic process	GO:0019752	92	0.024
regulation of multicellular organismal development	GO:2000026	414	0.024
nucleocytoplasmic transport	GO:0006913	72	0.024
regulation of cell differentiation	GO:0045595	302	0.024
eye morphogenesis	GO:0048592	260	0.023
mrna metabolic process	GO:0016071	124	0.023
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.023
single organism intracellular transport	GO:1902582	207	0.023
protein transport	GO:0015031	155	0.022
anterior posterior pattern specification	GO:0009952	136	0.022
negative regulation of cell cycle phase transition	GO:1901988	103	0.022
columnar cuboidal epithelial cell development	GO:0002066	249	0.022
negative regulation of biosynthetic process	GO:0009890	277	0.022
response to external biotic stimulus	GO:0043207	293	0.022
eye development	GO:0001654	323	0.022
protein catabolic process	GO:0030163	101	0.021
body morphogenesis	GO:0010171	2	0.021
regulation of rna splicing	GO:0043484	69	0.021
mitotic cell cycle embryonic	GO:0045448	38	0.021
dorsal ventral axis specification	GO:0009950	66	0.021
dorsal ventral pattern formation	GO:0009953	133	0.021
segmentation	GO:0035282	207	0.021
nucleobase containing small molecule metabolic process	GO:0055086	174	0.021
intracellular protein transport	GO:0006886	104	0.020
growth	GO:0040007	359	0.020
negative regulation of transcription dna templated	GO:0045892	237	0.020
regulation of cell cycle phase transition	GO:1901987	130	0.020
phagocytosis	GO:0006909	215	0.020
cell proliferation	GO:0008283	299	0.020
gland development	GO:0048732	191	0.020
microtubule organizing center organization	GO:0031023	168	0.019
purine nucleoside metabolic process	GO:0042278	127	0.019
cellular protein catabolic process	GO:0044257	83	0.019
appendage morphogenesis	GO:0035107	397	0.019
mitotic cell cycle phase transition	GO:0044772	138	0.019
single organism biosynthetic process	GO:0044711	206	0.019
chaeta development	GO:0022416	97	0.018
positive regulation of protein metabolic process	GO:0051247	128	0.018
alternative mrna splicing via spliceosome	GO:0000380	60	0.018
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.018
axis specification	GO:0009798	167	0.018
response to abiotic stimulus	GO:0009628	341	0.018
heterocycle catabolic process	GO:0046700	166	0.018
cellular macromolecule catabolic process	GO:0044265	136	0.018
defense response to other organism	GO:0098542	225	0.018
regulation of cell cycle process	GO:0010564	181	0.018
organonitrogen compound metabolic process	GO:1901564	318	0.018
regulation of cell proliferation	GO:0042127	163	0.017
dna conformation change	GO:0071103	105	0.017
epithelial cell differentiation	GO:0030855	322	0.017
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.017
tissue death	GO:0016271	102	0.017
g1 s transition of mitotic cell cycle	GO:0000082	31	0.017
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.017
chemosensory behavior	GO:0007635	106	0.017
dna damage checkpoint	GO:0000077	78	0.017
regulation of localization	GO:0032879	275	0.017
regulation of cysteine type endopeptidase activity involved in apoptotic process	GO:0043281	25	0.017
oxoacid metabolic process	GO:0043436	103	0.016
regulation of catabolic process	GO:0009894	170	0.016
modification dependent macromolecule catabolic process	GO:0043632	79	0.016
small gtpase mediated signal transduction	GO:0007264	88	0.016
ubiquitin dependent protein catabolic process	GO:0006511	78	0.016
cell cycle checkpoint	GO:0000075	95	0.016
developmental maturation	GO:0021700	172	0.015
determination of adult lifespan	GO:0008340	137	0.015
centrosome duplication	GO:0051298	121	0.015
protein localization	GO:0008104	284	0.015
humoral immune response	GO:0006959	117	0.015
male gamete generation	GO:0048232	201	0.015
programmed cell death	GO:0012501	257	0.014
regulation of immune system process	GO:0002682	176	0.014
regulation of transport	GO:0051049	181	0.014
protein targeting	GO:0006605	64	0.014
organonitrogen compound catabolic process	GO:1901565	128	0.014
response to nutrient levels	GO:0031667	114	0.014
pole plasm rna localization	GO:0007316	52	0.014
centrosome organization	GO:0051297	163	0.014
negative regulation of cellular biosynthetic process	GO:0031327	277	0.013
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.013
positive regulation of apoptotic signaling pathway	GO:2001235	4	0.013
regulation of cell death	GO:0010941	173	0.013
sensory organ morphogenesis	GO:0090596	260	0.013
epithelial cell development	GO:0002064	274	0.013
mrna splicing via spliceosome	GO:0000398	73	0.013
regulation of embryonic development	GO:0045995	68	0.013
compound eye photoreceptor development	GO:0042051	78	0.013
positive regulation of catalytic activity	GO:0043085	118	0.013
oocyte differentiation	GO:0009994	145	0.013
protein localization to organelle	GO:0033365	82	0.013
mrna catabolic process	GO:0006402	33	0.013
rna splicing via transesterification reactions	GO:0000375	73	0.012
single organism cellular localization	GO:1902580	180	0.012
regulation of organelle organization	GO:0033043	196	0.012
negative regulation of mitotic cell cycle	GO:0045930	109	0.012
actin cytoskeleton organization	GO:0030036	206	0.012
regulation of nervous system development	GO:0051960	248	0.012
protein import	GO:0017038	55	0.012
organic acid metabolic process	GO:0006082	103	0.012
protein targeting to nucleus	GO:0044744	51	0.012
defense response	GO:0006952	300	0.012
negative regulation of cell death	GO:0060548	81	0.012
imaginal disc derived wing morphogenesis	GO:0007476	337	0.012
regulation of mrna metabolic process	GO:1903311	72	0.012
regulation of neuron death	GO:1901214	26	0.011
aging	GO:0007568	143	0.011
retina development in camera type eye	GO:0060041	4	0.011
defense response to bacterium	GO:0042742	178	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.011
regulation of cellular ketone metabolic process	GO:0010565	3	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
chromatin remodeling	GO:0006338	72	0.011
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.011
negative regulation of response to stimulus	GO:0048585	258	0.011
establishment of protein localization to organelle	GO:0072594	62	0.011
cellular macromolecular complex assembly	GO:0034622	153	0.011
positive regulation of programmed cell death	GO:0043068	62	0.011
protein maturation	GO:0051604	71	0.011
regulation of programmed cell death	GO:0043067	152	0.011
regulation of cell shape	GO:0008360	113	0.011
cell maturation	GO:0048469	144	0.011
cellular protein localization	GO:0034613	160	0.011
purine nucleotide catabolic process	GO:0006195	109	0.011
nucleoside phosphate metabolic process	GO:0006753	162	0.011
olfactory behavior	GO:0042048	97	0.010
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.010
negative regulation of developmental growth	GO:0048640	64	0.010
chromosome segregation	GO:0007059	157	0.010
cellular amino acid metabolic process	GO:0006520	61	0.010
regulation of reproductive process	GO:2000241	54	0.010

nocte disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	nervous system disease	DOID:863	0	0.016
	disease of anatomical entity	DOID:7	0	0.016

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network