Drosophila melanogaster

69 known processes

Nek2 (Dmel_CG17256)

CG17256 gene product from transcript CG17256-RA

(Aliases: Dmel\CG17256,NEK2,DmNek2,Dm Nek2,CG17256)

Nek2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
centrosome cycleGO:00070981370.976
Human
centrosome organizationGO:00512971630.915
Human
centrosome duplicationGO:00512981210.862
microtubule organizing center organizationGO:00310231680.761
Human
mitotic spindle organizationGO:00070522200.678
Mouse
spindle organizationGO:00070512530.674
Mouse
mitotic nuclear divisionGO:00070672130.638
organelle localizationGO:00516401480.527
mitotic spindle stabilizationGO:004314860.330
regulation of cell cycleGO:00517262910.325
mitotic sister chromatid segregationGO:0000070870.292
Mouse
single fertilizationGO:0007338240.239
protein complex assemblyGO:00064612000.235
Mouse
sister chromatid segregationGO:0000819920.234
Mouse
regulation of mitotic cell cycleGO:00073461900.224
regulation of mitosisGO:0007088560.204
microtubule anchoringGO:0034453110.195
Human
regulation of microtubule cytoskeleton organizationGO:0070507410.186
Human
microtubule based movementGO:0007018510.181
negative regulation of cell cycleGO:00457861160.169
nucleus localizationGO:0051647340.164
protein complex biogenesisGO:00702712010.157
Mouse
macromolecular complex assemblyGO:00650032560.155
Mouse
spindle assembly involved in mitosisGO:0090307500.148
Mouse
single organism intracellular transportGO:19025822070.147
organelle assemblyGO:00709251980.147
Mouse
pronuclear migrationGO:003504640.135
cytoskeleton dependent cytokinesisGO:0061640810.131
developmental maturationGO:00217001720.130
cytokinesisGO:0000910900.130
attachment of spindle microtubules to kinetochoreGO:000860850.130
Human
cell divisionGO:00513012480.128
maintenance of location in cellGO:0051651280.126
Human
mitotic cell cycle embryonicGO:0045448380.126
protein localizationGO:00081042840.125
Human
oocyte differentiationGO:00099941450.123
meiotic cytokinesisGO:0033206330.121
nuclear divisionGO:00002803320.118
meiotic spindle organizationGO:0000212360.112
cellular macromolecule localizationGO:00707272200.111
Human
asymmetric cell divisionGO:0008356370.103
regulation of cell divisionGO:0051302720.101
regulation of microtubule based processGO:0032886490.097
Human
growthGO:00400073590.094
regulation of cytoskeleton organizationGO:0051493890.093
Human
regulation of phosphorus metabolic processGO:00511742100.092
cytoskeleton dependent intracellular transportGO:0030705440.092
single organism cellular localizationGO:19025801800.086
cell maturationGO:00484691440.084
maintenance of protein location in cellGO:0032507260.083
Human
regulation of mitotic cell cycle phase transitionGO:19019901300.081
cytokinetic processGO:0032506270.081
establishment of localization in cellGO:00516494020.081
purine ribonucleoside triphosphate catabolic processGO:00092071080.078
regulation of synapse assemblyGO:0051963940.077
mitotic spindle midzone assemblyGO:005125610.076
regulation of spindle elongationGO:003288710.075
regulation of cell cycle phase transitionGO:19019871300.075
spindle assembly involved in meiosisGO:0090306200.074
regulation of mitotic sister chromatid segregationGO:0033047280.072
establishment or maintenance of cell polarityGO:00071631670.065
regulation of organelle organizationGO:00330431960.064
positive regulation of developmental processGO:00510941430.064
centrosome separationGO:0051299200.063
Human
regulation of developmental growthGO:00486381740.063
intracellular protein transportGO:00068861040.062
regulation of growthGO:00400082330.061
mitotic spindle elongationGO:0000022810.061
open tracheal system developmentGO:00074242040.061
appendage morphogenesisGO:00351073970.059
microtubule cytoskeleton organization involved in mitosisGO:1902850520.059
Mouse
negative regulation of mitotic cell cycleGO:00459301090.058
purine nucleoside metabolic processGO:00422781270.057
regulation of mitotic spindle organizationGO:006023690.057
compound eye developmentGO:00487493070.055
cellular macromolecular complex assemblyGO:00346221530.054
positive regulation of protein localization to nucleusGO:1900182210.053
spermatogenesisGO:00072832000.053
nucleobase containing small molecule metabolic processGO:00550861740.052
mitotic cell cycle checkpointGO:0007093880.052
male meiosis cytokinesisGO:0007112260.051
regulation of intracellular transportGO:0032386640.051
organelle fissionGO:00482853400.050
sensory perception of mechanical stimulusGO:0050954720.050
nuclear migrationGO:0007097200.049
positive regulation of phosphorus metabolic processGO:00105621390.049
chromosome segregationGO:00070591570.047
Human Mouse
endomembrane system organizationGO:00102561190.046
axis specificationGO:00097981670.046
establishment of organelle localizationGO:00516561220.044
regulation of spindle organizationGO:0090224170.044
intracellular transportGO:00469072280.044
mitotic sister chromatid separationGO:0051306300.044
protein localization to nucleusGO:0034504550.041
protein phosphorylationGO:00064681690.041
female meiotic divisionGO:0007143700.041
intracellular signal transductionGO:00355563000.041
carbohydrate derivative metabolic processGO:19011352170.041
spindle assembly involved in female meiosisGO:0007056140.040
regulation of synapse organizationGO:00508071100.040
establishment of cell polarityGO:0030010400.040
microtubule polymerization or depolymerizationGO:0031109390.040
female meiosis iGO:000714480.040
oocyte dorsal ventral axis specificationGO:0007310340.039
establishment of chromosome localizationGO:0051303200.039
regulation of protein metabolic processGO:00512462560.039
purine containing compound catabolic processGO:00725231120.039
phosphorylationGO:00163102940.039
small molecule metabolic processGO:00442813050.038
imaginal disc derived appendage developmentGO:00487373990.038
nucleocytoplasmic transportGO:0006913720.038
regulation of multicellular organismal developmentGO:20000264140.038
organophosphate metabolic processGO:00196371950.038
catabolic processGO:00090564090.038
single organism biosynthetic processGO:00447112060.037
endocytosisGO:00068973100.037
nucleotide catabolic processGO:00091661090.036
meiotic nuclear divisionGO:00071261510.035
chromosome movement towards spindle poleGO:005130540.035
purine ribonucleotide catabolic processGO:00091541090.035
regulation of mitotic sister chromatid separationGO:0010965280.035
dephosphorylationGO:0016311510.035
neuronal stem cell divisionGO:0036445350.035
mitotic centrosome separationGO:000710080.035
organic substance catabolic processGO:19015753080.034
dendrite morphogenesisGO:00488131990.034
protein transportGO:00150311550.034
mitotic cell cycle phase transitionGO:00447721380.034
microtubule polymerizationGO:0046785150.034
protein localization to organelleGO:0033365820.033
ribose phosphate metabolic processGO:00196931450.033
positive regulation of transportGO:0051050920.033
positive regulation of multicellular organismal processGO:00512401430.033
syncytial blastoderm mitotic cell cycleGO:0035186210.033
carbohydrate derivative catabolic processGO:19011361180.032
spindle assemblyGO:0051225800.032
Mouse
cellular protein localizationGO:00346131600.032
Human
positive regulation of transcription factor import into nucleusGO:0042993190.032
positive regulation of mitotic sister chromatid separationGO:1901970100.032
positive regulation of protein transportGO:0051222370.031
mitotic cytokinesisGO:0000281500.031
protein dna complex assemblyGO:0065004630.031
cellular nitrogen compound catabolic processGO:00442701650.031
regionalizationGO:00030024160.031
regulation of cellular localizationGO:00603411360.031
Human
response to heatGO:0009408630.030
gastrulationGO:0007369700.030
glycosyl compound metabolic processGO:19016571270.030
wnt signaling pathwayGO:0016055980.030
equator specificationGO:004531740.030
regulation of protein import into nucleusGO:0042306280.030
regulation of cytoplasmic transportGO:1903649470.030
cell cycle comprising mitosis without cytokinesisGO:0033301250.029
male gamete generationGO:00482322010.029
protein importGO:0017038550.029
maintenance of protein locationGO:0045185280.029
Human
purine nucleoside triphosphate catabolic processGO:00091461080.028
nuclear transportGO:0051169720.028
centriole assemblyGO:0098534240.028
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.028
positive regulation of phosphate metabolic processGO:00459371390.028
positive regulation of nucleocytoplasmic transportGO:0046824240.027
cytoplasmic transportGO:00164821300.027
myotube differentiationGO:0014902460.027
single organism nuclear importGO:1902593510.027
developmental growthGO:00485892800.027
mitotic chromosome condensationGO:0007076220.027
single organism catabolic processGO:00447122280.027
golgi organizationGO:0007030660.027
protein polymerizationGO:0051258420.026
regulation of intracellular protein transportGO:0033157460.026
muscle organ developmentGO:00075171270.026
regulation of nuclear divisionGO:0051783580.026
neuron remodelingGO:0016322290.026
regulation of cytokinesisGO:003246530.026
meiosis iGO:0007127590.026
ribonucleoside triphosphate catabolic processGO:00092031080.026
dorsal ventral pattern formationGO:00099531330.025
response to organophosphorusGO:004668320.025
nucleoside triphosphate catabolic processGO:00091431080.025
ribonucleoside catabolic processGO:00424541120.024
regulation of hydrolase activityGO:0051336970.024
regulation of catalytic activityGO:00507901850.024
organonitrogen compound catabolic processGO:19015651280.024
positive regulation of response to stimulusGO:00485843230.024
regulation of mapk cascadeGO:0043408920.024
regulation of cyclin dependent protein serine threonine kinase activityGO:000007930.024
positive regulation of intracellular protein transportGO:0090316300.024
organic substance transportGO:00717022570.024
regulation of transcription factor import into nucleusGO:0042990220.024
metaphase anaphase transition of mitotic cell cycleGO:0007091280.023
regulation of protein localization to nucleusGO:1900180290.023
nucleoside phosphate catabolic processGO:19012921100.022
positive regulation of signalingGO:00230562430.022
negative regulation of cell cycle processGO:00109481090.022
metaphase anaphase transition of cell cycleGO:0044784280.022
negative regulation of cellular component organizationGO:00511291080.022
Human
regulation of nucleocytoplasmic transportGO:0046822350.022
heterocycle catabolic processGO:00467001660.022
purine ribonucleoside catabolic processGO:00461301120.022
purine containing compound metabolic processGO:00725211550.022
neurological system processGO:00508773580.022
fat soluble vitamin metabolic processGO:000677510.022
regulation of embryonic developmentGO:0045995680.022
purine nucleotide catabolic processGO:00061951090.022
programmed cell deathGO:00125012570.022
cellular protein complex assemblyGO:0043623710.021
glycosyl compound catabolic processGO:19016581120.021
jnk cascadeGO:0007254500.021
centriole centriole cohesionGO:001045750.021
Human
regulation of mitotic spindle elongationGO:003288810.021
organophosphate catabolic processGO:00464341120.021
maintenance of locationGO:0051235730.021
Human
cellular response to abiotic stimulusGO:0071214580.021
digestive tract morphogenesisGO:00485461270.021
positive regulation of mitotic metaphase anaphase transitionGO:0045842100.021
regulation of mitotic metaphase anaphase transitionGO:0030071260.020
protein import into nucleusGO:0006606510.020
regulation of cell cycle processGO:00105641810.020
negative regulation of developmental processGO:00510932010.020
proteasomal protein catabolic processGO:0010498590.020
microtubule based transportGO:0010970420.020
establishment of protein localizationGO:00451841630.020
regulation of intracellular signal transductionGO:19025312360.020
positive regulation of catalytic activityGO:00430851180.020
ribonucleoside triphosphate metabolic processGO:00091991190.019
regulation of nervous system developmentGO:00519602480.019
regulation of phosphate metabolic processGO:00192202100.019
tube developmentGO:00352952440.019
purine ribonucleoside triphosphate metabolic processGO:00092051190.019
rna 3 end processingGO:0031123450.019
neuroblast proliferationGO:0007405740.019
cell adhesionGO:00071551360.019
spindle midzone assemblyGO:005125540.019
spindle assembly involved in female meiosis iGO:000705750.019
nucleoside triphosphate metabolic processGO:00091411200.018
actin filament based processGO:00300292200.018
regulation of localizationGO:00328792750.018
Human
cell cell signaling involved in cell fate commitmentGO:00451682100.018
cilium organizationGO:0044782410.018
positive regulation of nfat protein import into nucleusGO:0051533160.018
embryonic pattern specificationGO:00098801740.018
vesicle mediated transportGO:00161923810.018
dendrite developmentGO:00163582040.018
protein targetingGO:0006605640.018
ribonucleotide metabolic processGO:00092591450.018
synaptic transmissionGO:00072682880.018
microtubule bundle formationGO:0001578270.018
spindle elongationGO:0051231830.018
aromatic compound catabolic processGO:00194391660.018
sensory perceptionGO:00076001960.018
segmentationGO:00352822070.018
ribonucleotide catabolic processGO:00092611090.018
purine ribonucleotide metabolic processGO:00091501450.018
nucleoside phosphate metabolic processGO:00067531620.017
mitotic g2 dna damage checkpointGO:0007095690.017
sensory organ precursor cell divisionGO:0045035100.017
nuclear importGO:0051170510.017
mitotic g2 m transition checkpointGO:0044818700.017
establishment of nucleus localizationGO:0040023260.017
cell deathGO:00082192790.017
cell motilityGO:00488702510.017
actin filament organizationGO:00070151260.017
axonogenesisGO:00074092900.017
regulation of synaptic growth at neuromuscular junctionGO:0008582890.017
organonitrogen compound metabolic processGO:19015643180.017
localization of cellGO:00516742570.017
regulation of transportGO:00510491810.017
regulation of cellular protein metabolic processGO:00322682430.016
mapk cascadeGO:00001651070.016
forebrain developmentGO:003090020.016
negative regulation of cell cycle g2 m phase transitionGO:190275080.016
eggshell formationGO:00307031050.016
axon developmentGO:00615642970.016
cellular protein modification processGO:00064644380.016
embryonic morphogenesisGO:00485982060.016
positive regulation of intracellular transportGO:0032388420.016
stem cell divisionGO:0017145690.016
regulation of epithelial cell proliferationGO:005067840.015
negative regulation of mitotic cell cycle phase transitionGO:19019911030.015
regulation of protein localizationGO:0032880760.015
Human
regulation of microtubule depolymerizationGO:0031114240.015
cell growthGO:00160491080.015
response to temperature stimulusGO:00092661060.015
purine ribonucleoside metabolic processGO:00461281270.015
blastoderm segmentationGO:00073501590.015
nucleotide metabolic processGO:00091171610.015
positive regulation of protein metabolic processGO:00512471280.015
purine ribonucleoside monophosphate catabolic processGO:0009169380.015
regulation of locomotionGO:0040012420.015
wing disc morphogenesisGO:00074723440.015
negative regulation of g2 m transition of mitotic cell cycleGO:001097280.015
salivary gland cell autophagic cell deathGO:0035071830.015
negative regulation of cell cycle phase transitionGO:19019881030.015
mitotic sister chromatid cohesionGO:000706460.015
chromosome separationGO:0051304420.015
gtp metabolic processGO:0046039720.015
regulation of molecular functionGO:00650092170.015
Mouse
negative regulation of microtubule depolymerizationGO:0007026210.015
eye photoreceptor cell differentiationGO:00017541450.014
Zebrafish
neural precursor cell proliferationGO:0061351750.014
cellular catabolic processGO:00442483720.014
regulation of centrosome cycleGO:004660570.014
macromolecule catabolic processGO:00090571610.014
purine nucleotide metabolic processGO:00061631460.014
positive regulation of metaphase anaphase transition of cell cycleGO:1902101100.014
neuromuscular junction developmentGO:00075281490.014
establishment of protein localization to organelleGO:0072594620.014
mitotic metaphase plate congressionGO:0007080130.014
embryonic development via the syncytial blastodermGO:00017001480.014
regulation of metaphase anaphase transition of cell cycleGO:1902099260.014
compound eye morphogenesisGO:00017452490.014
appendage developmentGO:00487364010.014
dna conformation changeGO:00711031050.014
organic cyclic compound catabolic processGO:19013611680.014
positive regulation of catabolic processGO:00098961050.013
regulation of phosphorylationGO:00423251470.013
cellular protein complex disassemblyGO:0043624350.013
establishment of spindle orientationGO:0051294180.013
germarium derived egg chamber formationGO:00072931010.013
synapse organizationGO:00508081960.013
spindle assembly involved in male meiosisGO:000705350.013
dna integrity checkpointGO:0031570810.013
skeletal muscle organ developmentGO:0060538480.013
g2 m transition of mitotic cell cycleGO:0000086190.013
negative regulation of phosphorus metabolic processGO:0010563450.013
negative regulation of growthGO:0045926840.013
signal transduction by phosphorylationGO:00230141070.013
small gtpase mediated signal transductionGO:0007264880.013
regulation of cell morphogenesisGO:00226041630.013
carboxylic acid metabolic processGO:0019752920.013
eye morphogenesisGO:00485922600.013
Zebrafish
regulation of cell developmentGO:00602842150.012
regulation of cell morphogenesis involved in differentiationGO:0010769610.012
cystoblast divisionGO:0007282100.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
positive regulation of hydrolase activityGO:0051345780.012
regulation of protein phosphorylationGO:0001932640.012
oocyte axis specificationGO:00073091080.012
negative regulation of rna biosynthetic processGO:19026792400.012
synaptic growth at neuromuscular junctionGO:00511241190.012
regulation of purine nucleotide catabolic processGO:0033121480.012
ribonucleoside metabolic processGO:00091191270.012
regulation of neuron projection developmentGO:0010975690.012
response to biotic stimulusGO:00096072940.012
asymmetric neuroblast divisionGO:0055059330.012
cytokinetic cell separationGO:000092010.012
regulation of response to stressGO:00801342000.012
lipid metabolic processGO:00066291210.012
regulation of gtp catabolic processGO:0033124440.012
negative regulation of phosphorylationGO:0042326350.012
immune response activating signal transductionGO:000275720.012
formation of anatomical boundaryGO:0048859370.012
response to radiationGO:00093141550.012
regulation of cellular component biogenesisGO:00440872010.012
regulation of nucleotide metabolic processGO:0006140620.011
regulation of anatomical structure sizeGO:00900661630.011
positive regulation of phosphorylationGO:0042327870.011
negative regulation of rna metabolic processGO:00512532510.011
regulation of protein transportGO:0051223570.011
regulation of proteolysisGO:0030162870.011
tripartite regional subdivisionGO:00073511030.011
calcium dependent cell cell adhesion via plasma membrane cell adhesion moleculesGO:001633990.011
endomitotic cell cycleGO:000711370.011
synapse assemblyGO:00074161430.011
nucleoside metabolic processGO:00091161270.011
phagocytosisGO:00069092150.011
digestive tract developmentGO:00485651490.011
positive regulation of protein kinase activityGO:0045860250.011
regulation of programmed cell deathGO:00430671520.011
cell cycle checkpointGO:0000075950.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
nucleoside catabolic processGO:00091641120.011
response to ionizing radiationGO:0010212320.011
negative regulation of developmental growthGO:0048640640.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
response to oxidative stressGO:0006979860.011
single organism cell adhesionGO:0098602470.011
nucleoside monophosphate catabolic processGO:0009125390.011
protein modification processGO:00362114380.011
chromosome localizationGO:0050000200.011
regulation of establishment of protein localizationGO:0070201610.011
regulation of protein targetingGO:1903533290.011
regulation of kinase activityGO:0043549530.011
photoreceptor cell developmentGO:0042461960.010
Zebrafish
regulation of catabolic processGO:00098941700.010
oocyte maturationGO:000155630.010
negative regulation of phosphate metabolic processGO:0045936450.010
actin cytoskeleton organizationGO:00300362060.010
regulation of neurogenesisGO:00507671580.010
segment polarity determinationGO:0007367250.010
protein targeting to nucleusGO:0044744510.010
chemotaxisGO:00069352490.010
purine ribonucleoside monophosphate metabolic processGO:0009167500.010
cellular lipid metabolic processGO:0044255830.010
cell migrationGO:00164772380.010
negative regulation of gene expressionGO:00106293870.010

Nek2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.023
cancerDOID:16200.018
organ system cancerDOID:005068600.018