Drosophila melanogaster

36 known processes

px (Dmel_CG4444)

plexus

(Aliases: CG4444,l(2)k08134,l(2)k08316,Dmel\CG4444)

px biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of rna metabolic processGO:00512542710.478
positive regulation of nitrogen compound metabolic processGO:00511733540.467
regulation of intracellular signal transductionGO:19025312360.412
positive regulation of biosynthetic processGO:00098913160.374
positive regulation of cellular biosynthetic processGO:00313283160.299
negative regulation of transcription dna templatedGO:00458922370.268
positive regulation of transcription dna templatedGO:00458932660.264
cellular protein modification processGO:00064644380.246
regulation of cellular protein metabolic processGO:00322682430.220
response to oxygen containing compoundGO:19017002000.205
vesicle mediated transportGO:00161923810.201
immune system developmentGO:0002520570.201
ribonucleoside triphosphate catabolic processGO:00092031080.200
immune system processGO:00023763470.198
appendage developmentGO:00487364010.196
regulation of transcription from rna polymerase ii promoterGO:00063573780.194
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.194
positive regulation of rna biosynthetic processGO:19026802660.194
negative regulation of rna biosynthetic processGO:19026792400.191
transcription from rna polymerase ii promoterGO:00063663680.187
regionalizationGO:00030024160.177
regulation of catalytic activityGO:00507901850.171
purine ribonucleotide catabolic processGO:00091541090.170
regulation of phosphorus metabolic processGO:00511742100.152
regulation of molecular functionGO:00650092170.148
establishment of localization in cellGO:00516494020.148
nucleobase containing compound catabolic processGO:00346551650.142
positive regulation of nucleobase containing compound metabolic processGO:00459353320.139
regulation of immune system processGO:00026821760.133
regulation of phosphate metabolic processGO:00192202100.131
aromatic compound catabolic processGO:00194391660.130
positive regulation of nucleic acid templated transcriptionGO:19035082660.129
dendrite developmentGO:00163582040.127
regulation of apoptotic processGO:00429811300.125
positive regulation of hydrolase activityGO:0051345780.124
negative regulation of rna metabolic processGO:00512532510.121
humoral immune responseGO:00069591170.119
covalent chromatin modificationGO:00165691060.115
deathGO:00162652840.115
protein acetylationGO:0006473390.110
positive regulation of macromolecule biosynthetic processGO:00105572830.109
positive regulation of cellular catabolic processGO:0031331950.105
heterocycle catabolic processGO:00467001660.103
embryo development ending in birth or egg hatchingGO:00097921520.102
positive regulation of multicellular organismal processGO:00512401430.101
regulation of response to biotic stimulusGO:0002831630.100
positive regulation of phosphorus metabolic processGO:00105621390.098
purine nucleoside triphosphate metabolic processGO:00091441190.094
positive regulation of catabolic processGO:00098961050.094
regulation of organelle organizationGO:00330431960.094
programmed cell deathGO:00125012570.092
regulation of cellular catabolic processGO:00313291570.091
positive regulation of catalytic activityGO:00430851180.090
intracellular signal transductionGO:00355563000.089
positive regulation of phosphate metabolic processGO:00459371390.088
positive regulation of nucleotide metabolic processGO:0045981550.088
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.087
negative regulation of biosynthetic processGO:00098902770.086
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.086
regulation of response to external stimulusGO:00321011150.085
glycosyl compound catabolic processGO:19016581120.085
negative regulation of cell communicationGO:00106482230.085
ommochrome metabolic processGO:0046152190.085
regulation of multi organism processGO:00439001310.085
regulation of protein metabolic processGO:00512462560.084
positive regulation of macromolecule metabolic processGO:00106044050.083
rna catabolic processGO:0006401370.083
organonitrogen compound metabolic processGO:19015643180.083
nuclear divisionGO:00002803320.083
regulation of localizationGO:00328792750.083
endocytosisGO:00068973100.082
guanosine containing compound catabolic processGO:1901069740.080
apoptotic processGO:00069151590.078
imaginal disc derived appendage morphogenesisGO:00351143950.076
regulation of response to stressGO:00801342000.075
positive regulation of molecular functionGO:00440931360.075
catabolic processGO:00090564090.075
gtp metabolic processGO:0046039720.074
positive regulation of cellular component organizationGO:00511301560.071
purine ribonucleoside metabolic processGO:00461281270.071
negative regulation of nucleobase containing compound metabolic processGO:00459342610.071
post embryonic appendage morphogenesisGO:00351203850.070
protein complex assemblyGO:00064612000.070
negative regulation of nucleic acid templated transcriptionGO:19035072400.070
cellular nitrogen compound catabolic processGO:00442701650.070
nucleoside catabolic processGO:00091641120.068
organic acid metabolic processGO:00060821030.068
regulation of gene expression epigeneticGO:00400291280.068
negative regulation of signal transductionGO:00099682060.065
negative regulation of cell deathGO:0060548810.065
single organism behaviorGO:00447083910.065
negative regulation of macromolecule biosynthetic processGO:00105582700.064
macromolecular complex assemblyGO:00650032560.064
chromatin organizationGO:00063252070.063
regulation of cellular amine metabolic processGO:003323830.063
regulation of antimicrobial humoral responseGO:0002759500.062
cellular amino acid metabolic processGO:0006520610.062
negative regulation of gene expressionGO:00106293870.061
purine nucleotide catabolic processGO:00061951090.061
chromatin modificationGO:00165681470.059
cell migrationGO:00164772380.058
oxoacid metabolic processGO:00434361030.058
regulation of hydrolase activityGO:0051336970.057
cell motilityGO:00488702510.056
organelle fissionGO:00482853400.056
purine ribonucleoside triphosphate metabolic processGO:00092051190.056
positive regulation of gtpase activityGO:0043547430.056
purine nucleoside metabolic processGO:00422781270.055
mrna metabolic processGO:00160711240.055
regulation of protein modification processGO:00313991120.055
regulation of gtpase activityGO:0043087440.054
ribonucleotide catabolic processGO:00092611090.054
organic cyclic compound catabolic processGO:19013611680.052
regulation of production of molecular mediator of immune responseGO:0002700440.051
response to abiotic stimulusGO:00096283410.051
cellular catabolic processGO:00442483720.051
nucleoside triphosphate metabolic processGO:00091411200.051
compound eye developmentGO:00487493070.050
jak stat cascadeGO:0007259490.050
protein complex biogenesisGO:00702712010.050
regulation of programmed cell deathGO:00430671520.050
response to external biotic stimulusGO:00432072930.049
positive regulation of protein metabolic processGO:00512471280.049
regulation of multicellular organismal developmentGO:20000264140.049
regulation of endocytosisGO:0030100370.049
purine ribonucleotide metabolic processGO:00091501450.049
carboxylic acid metabolic processGO:0019752920.048
regulation of cellular component biogenesisGO:00440872010.048
negative regulation of response to stimulusGO:00485852580.048
axonogenesisGO:00074092900.047
organic substance catabolic processGO:19015753080.047
positive regulation of purine nucleotide metabolic processGO:1900544550.047
cytoplasmic transportGO:00164821300.046
purine nucleoside catabolic processGO:00061521120.046
response to other organismGO:00517072930.046
mrna processingGO:00063971040.046
ribonucleoside triphosphate metabolic processGO:00091991190.046
regulation of immune effector processGO:0002697520.045
small gtpase mediated signal transductionGO:0007264880.045
leg disc morphogenesisGO:0007478800.045
taxisGO:00423303040.045
chemotaxisGO:00069352490.044
purine containing compound catabolic processGO:00725231120.044
antimicrobial humoral responseGO:0019730990.044
nucleoside triphosphate catabolic processGO:00091431080.043
imaginal disc derived appendage developmentGO:00487373990.043
ribonucleotide metabolic processGO:00092591450.042
single organism catabolic processGO:00447122280.042
peptidyl amino acid modificationGO:00181931050.042
positive regulation of gene expressionGO:00106282900.042
tissue morphogenesisGO:00487292970.042
cellular response to oxygen containing compoundGO:1901701790.042
gene silencing by mirnaGO:0035195220.042
body morphogenesisGO:001017120.041
negative regulation of apoptotic processGO:0043066630.041
chromosome organizationGO:00512763600.040
ribonucleoside metabolic processGO:00091191270.040
positive regulation of cellular protein metabolic processGO:00322701180.040
protein modification by small protein conjugation or removalGO:00706471060.040
carbohydrate derivative metabolic processGO:19011352170.039
regulation of cellular amide metabolic processGO:0034248390.039
multicellular organismal agingGO:00102591400.039
establishment of organelle localizationGO:00516561220.039
regulation of cell morphogenesisGO:00226041630.038
cell deathGO:00082192790.038
response to organic substanceGO:00100332840.038
negative regulation of signalingGO:00230572190.038
cell divisionGO:00513012480.037
organelle localizationGO:00516401480.037
positive regulation of cellular component biogenesisGO:0044089800.037
nucleobase containing small molecule metabolic processGO:00550861740.037
purine nucleotide metabolic processGO:00061631460.037
rho protein signal transductionGO:0007266140.037
segmentationGO:00352822070.037
regulation of transportGO:00510491810.036
glycosyl compound metabolic processGO:19016571270.036
ras protein signal transductionGO:0007265880.035
negative regulation of nitrogen compound metabolic processGO:00511722650.035
response to alcoholGO:0097305950.035
hematopoietic or lymphoid organ developmentGO:0048534570.034
regulation of nucleotide catabolic processGO:0030811480.034
nucleoside phosphate metabolic processGO:00067531620.034
nucleotide metabolic processGO:00091171610.034
open tracheal system developmentGO:00074242040.034
organophosphate metabolic processGO:00196371950.034
positive regulation of nucleoside metabolic processGO:0045979470.033
immune responseGO:00069552460.033
agingGO:00075681430.033
enzyme linked receptor protein signaling pathwayGO:00071671790.033
purine containing compound metabolic processGO:00725211550.033
regulation of dna templated transcription elongationGO:0032784170.033
purine nucleoside triphosphate catabolic processGO:00091461080.033
growthGO:00400073590.033
small molecule metabolic processGO:00442813050.032
determination of adult lifespanGO:00083401370.032
nucleotide catabolic processGO:00091661090.032
regulation of cellular ketone metabolic processGO:001056530.032
central nervous system developmentGO:00074172010.032
positive regulation of protein modification processGO:0031401580.032
response to biotic stimulusGO:00096072940.032
regulation of small gtpase mediated signal transductionGO:0051056930.032
antimicrobial peptide productionGO:0002775460.031
positive regulation of cellular amino acid metabolic processGO:004576400.030
multi organism behaviorGO:00517051750.030
dna metabolic processGO:00062592270.030
regulation of antimicrobial peptide productionGO:0002784440.030
cellular response to dna damage stimulusGO:00069742230.030
phagocytosisGO:00069092150.030
guanosine containing compound metabolic processGO:1901068740.030
phosphorylationGO:00163102940.030
regulation of purine nucleotide catabolic processGO:0033121480.029
nucleoside metabolic processGO:00091161270.029
eye developmentGO:00016543230.029
wing disc morphogenesisGO:00074723440.028
regulation of nucleoside metabolic processGO:0009118500.028
cellular response to external stimulusGO:0071496660.028
regulation of cellular response to stressGO:0080135890.028
regulation of cellular amino acid metabolic processGO:000652100.028
cellular response to organic substanceGO:00713101320.028
muscle cell differentiationGO:00426921030.028
negative regulation of cellular biosynthetic processGO:00313272770.027
ocellus pigmentationGO:0033060190.027
hemopoiesisGO:0030097460.027
positive regulation of nucleotide catabolic processGO:0030813460.027
sensory organ morphogenesisGO:00905962600.027
protein phosphorylationGO:00064681690.027
response to organonitrogen compoundGO:0010243750.027
regulation of cell differentiationGO:00455953020.026
peptide metabolic processGO:0006518800.026
positive regulation of phosphorylationGO:0042327870.026
histone modificationGO:00165701060.026
nephron epithelium developmentGO:007200930.026
regulation of cell developmentGO:00602842150.026
gtp catabolic processGO:0006184720.026
homeostatic processGO:00425921990.026
single organism intracellular transportGO:19025822070.026
macromolecule catabolic processGO:00090571610.026
appendage morphogenesisGO:00351073970.026
organophosphate catabolic processGO:00464341120.025
cellular response to chemical stimulusGO:00708871990.025
respiratory system developmentGO:00605412130.025
purine ribonucleoside catabolic processGO:00461301120.025
organonitrogen compound catabolic processGO:19015651280.025
eye morphogenesisGO:00485922600.025
ncrna metabolic processGO:0034660430.024
purine ribonucleoside triphosphate catabolic processGO:00092071080.024
outflow tract morphogenesisGO:000315140.024
positive regulation of gtp catabolic processGO:0033126430.024
dendrite morphogenesisGO:00488131990.024
regulation of cellular localizationGO:00603411360.024
defense responseGO:00069523000.024
regulation of phosphorylationGO:00423251470.024
nucleoside phosphate catabolic processGO:19012921100.023
carbohydrate derivative catabolic processGO:19011361180.023
regulation of gtp catabolic processGO:0033124440.023
organic substance transportGO:00717022570.023
locomotory behaviorGO:00076261760.023
striated muscle cell differentiationGO:0051146900.023
regulation of cell proliferationGO:00421271630.023
regulation of ras protein signal transductionGO:0046578930.023
ribose phosphate metabolic processGO:00196931450.023
actin cytoskeleton organizationGO:00300362060.023
sister chromatid segregationGO:0000819920.022
response to radiationGO:00093141550.022
negative regulation of cellular metabolic processGO:00313243820.022
positive regulation of response to external stimulusGO:0032103440.022
protein modification by small protein removalGO:0070646280.022
molting cycle chitin based cuticleGO:0007591560.022
positive regulation of signalingGO:00230562430.022
endomembrane system organizationGO:00102561190.022
tube developmentGO:00352952440.022
spindle organizationGO:00070512530.021
myoblast fusionGO:0007520430.021
secondary metabolic processGO:0019748750.021
cellular ketone metabolic processGO:0042180240.021
gland developmentGO:00487321910.021
pigmentationGO:0043473750.021
anterior posterior pattern specificationGO:00099521360.021
developmental pigmentationGO:0048066680.021
regulation of rho protein signal transductionGO:0035023200.021
regulation of immune responseGO:00507761180.021
larval developmentGO:00021641040.021
regulation of nucleotide metabolic processGO:0006140620.021
peptidyl lysine modificationGO:0018205570.020
regulation of cell cycle processGO:00105641810.020
protein modification processGO:00362114380.020
regulation of mitotic cell cycleGO:00073461900.020
cellular macromolecular complex assemblyGO:00346221530.020
mrna catabolic processGO:0006402330.020
ribonucleoside catabolic processGO:00424541120.020
response to endogenous stimulusGO:00097191190.020
regulation of humoral immune responseGO:0002920510.020
embryonic morphogenesisGO:00485982060.020
regulation of cell cycleGO:00517262910.020
regulation of antimicrobial peptide biosynthetic processGO:0002805380.020
response to lipidGO:0033993380.020
regulation of proteolysisGO:0030162870.020
regulation of cytoskeleton organizationGO:0051493890.019
regulation of vesicle mediated transportGO:0060627590.019
golgi organizationGO:0007030660.019
nephron developmentGO:007200630.019
kidney epithelium developmentGO:007207330.019
myotube differentiationGO:0014902460.019
regulation of anatomical structure morphogenesisGO:00226032420.019
anatomical structure homeostasisGO:0060249970.018
cellular macromolecule catabolic processGO:00442651360.018
embryonic pattern specificationGO:00098801740.018
cellular macromolecule localizationGO:00707272200.018
imaginal disc derived wing morphogenesisGO:00074763370.018
response to lipopolysaccharideGO:003249640.018
regulation of cell deathGO:00109411730.017
positive regulation of intracellular signal transductionGO:19025331160.017
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.017
negative regulation of cell cycleGO:00457861160.017
response to organic cyclic compoundGO:0014070890.017
gene silencingGO:00164581380.017
negative regulation of programmed cell deathGO:0043069720.016
tube morphogenesisGO:00352391910.016
rna processingGO:00063961470.016
localization of cellGO:00516742570.016
intracellular transportGO:00469072280.016
cellular protein complex assemblyGO:0043623710.016
developmental programmed cell deathGO:00106231380.016
positive regulation of rho gtpase activityGO:0032321190.016
regulation of transferase activityGO:0051338580.016
regulation of establishment of protein localizationGO:0070201610.016
stem cell developmentGO:0048864790.016
regulation of growthGO:00400082330.016
response to light stimulusGO:00094161240.016
regulation of cell shapeGO:00083601130.015
hematopoietic progenitor cell differentiationGO:000224410.015
mitotic nuclear divisionGO:00070672130.015
cell fate determinationGO:0001709910.015
peptide biosynthetic processGO:0043043420.015
axon guidanceGO:00074112330.015
immune effector processGO:0002252980.015
organonitrogen compound biosynthetic processGO:19015661170.015
pigment metabolic processGO:0042440840.015
ocellus pigment metabolic processGO:0046158190.015
negative regulation of intracellular signal transductionGO:1902532570.015
actin filament based processGO:00300292200.015
regulation of intracellular transportGO:0032386640.014
brain developmentGO:00074201200.014
positive regulation of developmental processGO:00510941430.014
leg disc developmentGO:0035218920.014
cellular amide metabolic processGO:0043603800.014
nucleocytoplasmic transportGO:0006913720.014
regulation of mrna processingGO:0050684710.014
renal tubule developmentGO:0061326640.014
negative regulation of developmental processGO:00510932010.014
negative regulation of molecular functionGO:0044092510.014
regulation of protein localizationGO:0032880760.014
cell proliferationGO:00082832990.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
protein ubiquitinationGO:0016567700.014
methylationGO:0032259470.014
positive regulation of ras gtpase activityGO:0032320360.013
photoreceptor cell differentiationGO:00465301700.013
regulation of intracellular protein transportGO:0033157460.013
meiotic cell cycleGO:00513211710.013
mapk cascadeGO:00001651070.013
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
rna 3 end processingGO:0031123450.013
toll signaling pathwayGO:0008063250.013
developmental maturationGO:00217001720.013
signal transduction in response to dna damageGO:004277030.013
oocyte developmentGO:00485991240.013
male gamete generationGO:00482322010.013
proteolysisGO:00065081920.013
muscle fiber developmentGO:0048747120.013
cellular response to endogenous stimulusGO:0071495800.013
positive regulation of response to stimulusGO:00485843230.013
epithelial cell developmentGO:00020642740.013
macromolecule methylationGO:0043414450.012
regulation of ras gtpase activityGO:0032318380.012
rna transportGO:0050658460.012
response to nutrient levelsGO:00316671140.012
inter male aggressive behaviorGO:0002121600.012
regulation of cell divisionGO:0051302720.012
regulation of chitin based cuticle tanningGO:0007564140.012
negative regulation of cell differentiationGO:00455961430.012
regulation of purine nucleotide metabolic processGO:1900542620.012
neural precursor cell proliferationGO:0061351750.012
nuclear transportGO:0051169720.012
actomyosin structure organizationGO:0031032560.012
single organism cellular localizationGO:19025801800.012
establishment or maintenance of cell polarityGO:00071631670.012
negative regulation of cellular component organizationGO:00511291080.012
nuclear transcribed mrna catabolic processGO:0000956240.012
dna templated transcription elongationGO:0006354180.012
positive regulation of cellular amine metabolic processGO:003324000.011
camera type eye developmentGO:004301040.011
nucleobase containing compound transportGO:0015931560.011
cellular amine metabolic processGO:0044106120.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
syncytium formation by plasma membrane fusionGO:0000768430.011
aggressive behaviorGO:0002118630.011
morphogenesis of an epitheliumGO:00020092760.011
posttranscriptional regulation of gene expressionGO:00106081450.011
notch signaling pathwayGO:00072191200.011
negative regulation of cellular protein metabolic processGO:0032269850.011
negative regulation of gene expression epigeneticGO:0045814770.011
regulation of nucleocytoplasmic transportGO:0046822350.011
mitotic spindle organizationGO:00070522200.011
positive regulation of protein phosphorylationGO:0001934340.010
response to inorganic substanceGO:0010035440.010
regulation of protein phosphorylationGO:0001932640.010
regulation of protein kinase activityGO:0045859510.010
dna repairGO:0006281540.010
protein localizationGO:00081042840.010
regulation of bmp signaling pathwayGO:0030510230.010
negative regulation of phosphorus metabolic processGO:0010563450.010
response to monosaccharideGO:003428440.010
regulation of neural precursor cell proliferationGO:2000177350.010
stem cell differentiationGO:00488631170.010
urogenital system developmentGO:0001655720.010
regulation of cytoplasmic transportGO:1903649470.010
cellular response to organic cyclic compoundGO:0071407320.010

px disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.067
nervous system diseaseDOID:86300.030
cardiovascular system diseaseDOID:128700.016
integumentary system diseaseDOID:1600.013
hair diseaseDOID:42100.013
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012
central nervous system diseaseDOID:33100.012
disease of metabolismDOID:001466700.011
vascular diseaseDOID:17800.011