IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

yellow-g (Dmel_CG5717)

CG5717 gene product from transcript CG5717-RA

(Aliases: Dmel\CG5717,CG5717)

FLYBASE: FBgn0041709
Entrez: 38294
UniProtKB: Q9W029

Process Predictions
Disease Predictions

yellow-g biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
ovarian follicle cell development	GO:0030707	248	0.145
organonitrogen compound metabolic process	GO:1901564	318	0.109	Fly
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.104
positive regulation of signaling	GO:0023056	243	0.100
chorion containing eggshell formation	GO:0007304	105	0.100
response to biotic stimulus	GO:0009607	294	0.081
eggshell formation	GO:0030703	105	0.075
defense response	GO:0006952	300	0.070
response to other organism	GO:0051707	293	0.067
innate immune response	GO:0045087	144	0.064
eggshell chorion assembly	GO:0007306	66	0.064
epithelial cell differentiation	GO:0030855	322	0.062
response to external biotic stimulus	GO:0043207	293	0.061
immune response	GO:0006955	246	0.055
regulation of phosphate metabolic process	GO:0019220	210	0.050
small molecule metabolic process	GO:0044281	305	0.048
cellular component assembly involved in morphogenesis	GO:0010927	151	0.048
regulation of phosphorus metabolic process	GO:0051174	210	0.047
positive regulation of signal transduction	GO:0009967	223	0.047
phosphorylation	GO:0016310	294	0.044
organonitrogen compound biosynthetic process	GO:1901566	117	0.044	Fly
mapk cascade	GO:0000165	107	0.043
regulation of mapk cascade	GO:0043408	92	0.041
columnar cuboidal epithelial cell development	GO:0002066	249	0.039
carboxylic acid metabolic process	GO:0019752	92	0.039
respiratory system development	GO:0060541	213	0.038
appendage development	GO:0048736	401	0.038
vesicle mediated transport	GO:0016192	381	0.037
regulation of intracellular signal transduction	GO:1902531	236	0.035
response to nitrogen compound	GO:1901698	90	0.035
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.035
cellular response to heat	GO:0034605	24	0.034
multi organism behavior	GO:0051705	175	0.034
positive regulation of cell communication	GO:0010647	250	0.033
endocytosis	GO:0006897	310	0.033
response to bacterium	GO:0009617	198	0.033
organic acid metabolic process	GO:0006082	103	0.032
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.032
imaginal disc derived wing morphogenesis	GO:0007476	337	0.032
regulation of cellular amine metabolic process	GO:0033238	3	0.031
neurological system process	GO:0050877	358	0.031
intracellular signal transduction	GO:0035556	300	0.031
single organism behavior	GO:0044708	391	0.030
body morphogenesis	GO:0010171	2	0.030
organic substance catabolic process	GO:1901575	308	0.030
regulation of erbb signaling pathway	GO:1901184	42	0.030
cellular amino acid metabolic process	GO:0006520	61	0.029
compound eye development	GO:0048749	307	0.029
regulation of nervous system development	GO:0051960	248	0.028
anatomical structure homeostasis	GO:0060249	97	0.028
xenobiotic catabolic process	GO:0042178	1	0.028
signal transduction by phosphorylation	GO:0023014	107	0.027
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.027
immune system process	GO:0002376	347	0.027
response to organophosphorus	GO:0046683	2	0.026
open tracheal system development	GO:0007424	204	0.026
compound eye morphogenesis	GO:0001745	249	0.026
positive regulation of response to stimulus	GO:0048584	323	0.026
regulation of multicellular organismal development	GO:2000026	414	0.026
organonitrogen compound catabolic process	GO:1901565	128	0.026
single organism biosynthetic process	GO:0044711	206	0.026
regulation of cellular ketone metabolic process	GO:0010565	3	0.026
response to abiotic stimulus	GO:0009628	341	0.025
secondary metabolic process	GO:0019748	75	0.025
compound eye photoreceptor cell differentiation	GO:0001751	140	0.025
regulation of cellular amino acid metabolic process	GO:0006521	0	0.024
cellular ketone metabolic process	GO:0042180	24	0.024
regulation of mitotic cell cycle	GO:0007346	190	0.024
synaptic transmission	GO:0007268	288	0.024
regulation of cell cycle	GO:0051726	291	0.024
gland development	GO:0048732	191	0.024
regulation of molecular function	GO:0065009	217	0.024
stem cell fate commitment	GO:0048865	25	0.023
axon development	GO:0061564	297	0.023
defense response to other organism	GO:0098542	225	0.022
benzene containing compound metabolic process	GO:0042537	3	0.022
regulation of protein metabolic process	GO:0051246	256	0.022
defense response to bacterium	GO:0042742	178	0.022
purine ribonucleotide metabolic process	GO:0009150	145	0.022
spindle organization	GO:0007051	253	0.022
epithelium migration	GO:0090132	148	0.021
cellular amine metabolic process	GO:0044106	12	0.021
response to organic substance	GO:0010033	284	0.021
cellular catabolic process	GO:0044248	372	0.021
amine metabolic process	GO:0009308	12	0.021
eye morphogenesis	GO:0048592	260	0.021
oxoacid metabolic process	GO:0043436	103	0.021
homeostatic process	GO:0042592	199	0.021
post embryonic appendage morphogenesis	GO:0035120	385	0.021
organic cyclic compound catabolic process	GO:1901361	168	0.021
catabolic process	GO:0009056	409	0.021
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.020
response to lipopolysaccharide	GO:0032496	4	0.020
proteolysis	GO:0006508	192	0.020
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.020
positive regulation of phosphate metabolic process	GO:0045937	139	0.020
positive regulation of biosynthetic process	GO:0009891	316	0.020
immune response regulating signaling pathway	GO:0002764	2	0.020
imaginal disc derived appendage development	GO:0048737	399	0.020
defense response to gram negative bacterium	GO:0050829	94	0.020
regulation of catalytic activity	GO:0050790	185	0.020
cellular homeostasis	GO:0019725	80	0.020
positive regulation of phosphorus metabolic process	GO:0010562	139	0.019
carbohydrate derivative metabolic process	GO:1901135	217	0.019
dorsal ventral pattern formation	GO:0009953	133	0.019
eye development	GO:0001654	323	0.019
sensory organ morphogenesis	GO:0090596	260	0.019
ovarian follicle cell migration	GO:0007297	121	0.019
macromolecule catabolic process	GO:0009057	161	0.019
positive regulation of peptidyl tyrosine phosphorylation	GO:0050731	4	0.019
cellular response to chemical stimulus	GO:0070887	199	0.019
organophosphate metabolic process	GO:0019637	195	0.018
connective tissue development	GO:0061448	3	0.018
negative regulation of response to stimulus	GO:0048585	258	0.018
central nervous system development	GO:0007417	201	0.018
androgen metabolic process	GO:0008209	1	0.018
epithelial cell migration open tracheal system	GO:0007427	32	0.018
aggressive behavior	GO:0002118	63	0.018
response to wounding	GO:0009611	94	0.018
phagocytosis	GO:0006909	215	0.018
forebrain development	GO:0030900	2	0.018
response to mercury ion	GO:0046689	3	0.018
salivary gland morphogenesis	GO:0007435	145	0.018
response to light stimulus	GO:0009416	124	0.018
steroid catabolic process	GO:0006706	1	0.018
exocrine system development	GO:0035272	162	0.018
positive regulation of rna metabolic process	GO:0051254	271	0.018
nucleoside phosphate metabolic process	GO:0006753	162	0.018
positive regulation of intracellular signal transduction	GO:1902533	116	0.018
regulation of catabolic process	GO:0009894	170	0.017
stress activated mapk cascade	GO:0051403	52	0.017
nucleoside metabolic process	GO:0009116	127	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.017
single organism catabolic process	GO:0044712	228	0.017
cellular response to dna damage stimulus	GO:0006974	223	0.017
border follicle cell migration	GO:0007298	113	0.017
regulation of neurogenesis	GO:0050767	158	0.017
pigmentation	GO:0043473	75	0.017
head development	GO:0060322	135	0.017
regulation of cell cycle process	GO:0010564	181	0.017
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.017
ribonucleoside metabolic process	GO:0009119	127	0.017
ribonucleotide metabolic process	GO:0009259	145	0.017
protein maturation	GO:0051604	71	0.017
regulation of neuronal synaptic plasticity	GO:0048168	8	0.017
jnk cascade	GO:0007254	50	0.017
purine nucleoside metabolic process	GO:0042278	127	0.017
appendage morphogenesis	GO:0035107	397	0.016
histolysis	GO:0007559	102	0.016
protein phosphorylation	GO:0006468	169	0.016
ribonucleoside triphosphate metabolic process	GO:0009199	119	0.016
positive regulation of phosphorylation	GO:0042327	87	0.016
cellular response to lipopolysaccharide	GO:0071222	3	0.016
regulation of tube architecture open tracheal system	GO:0035152	68	0.016
hormone catabolic process	GO:0042447	3	0.016
salivary gland development	GO:0007431	162	0.016
segmentation	GO:0035282	207	0.016
wnt signaling pathway	GO:0016055	98	0.016
positive regulation of cell motility	GO:2000147	3	0.016
epithelial cell development	GO:0002064	274	0.016
hindbrain development	GO:0030902	2	0.016
nucleobase containing small molecule metabolic process	GO:0055086	174	0.015
response to organic cyclic compound	GO:0014070	89	0.015
positive regulation of transcription dna templated	GO:0045893	266	0.015
negative regulation of mitotic cell cycle	GO:0045930	109	0.015
response to radiation	GO:0009314	155	0.015
aromatic compound catabolic process	GO:0019439	166	0.015
positive regulation of cellular catabolic process	GO:0031331	95	0.015
regulation of phosphorylation	GO:0042325	147	0.015
compound eye photoreceptor fate commitment	GO:0001752	36	0.015
cell proliferation	GO:0008283	299	0.015
organic substance transport	GO:0071702	257	0.015
intracellular transport	GO:0046907	228	0.015
protein modification process	GO:0036211	438	0.015
immune response activating signal transduction	GO:0002757	2	0.015
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.015
tube morphogenesis	GO:0035239	191	0.015
cell division	GO:0051301	248	0.014
regulation of response to stress	GO:0080134	200	0.014
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.014
erbb signaling pathway	GO:0038127	58	0.014
tissue homeostasis	GO:0001894	36	0.014
developmental programmed cell death	GO:0010623	138	0.014
protein modification by small protein conjugation or removal	GO:0070647	106	0.014
cholesterol homeostasis	GO:0042632	3	0.014
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.014
ras protein signal transduction	GO:0007265	88	0.014
regulation of epithelial cell proliferation	GO:0050678	4	0.014
small gtpase mediated signal transduction	GO:0007264	88	0.014
ribonucleoside catabolic process	GO:0042454	112	0.014
establishment of planar polarity	GO:0001736	87	0.014
imaginal disc derived wing vein specification	GO:0007474	48	0.014
regulation of cellular component biogenesis	GO:0044087	201	0.014
protein processing	GO:0016485	68	0.014
gland morphogenesis	GO:0022612	145	0.014
positive regulation of cellular amine metabolic process	GO:0033240	0	0.014
behavioral response to ethanol	GO:0048149	49	0.014
regulation of immune response	GO:0050776	118	0.014
cuticle development	GO:0042335	86	0.014
positive regulation of mapk cascade	GO:0043410	63	0.014
regionalization	GO:0003002	416	0.013
eye photoreceptor cell differentiation	GO:0001754	145	0.013
multicellular organismal homeostasis	GO:0048871	41	0.013
positive regulation of catabolic process	GO:0009896	105	0.013
nucleoside catabolic process	GO:0009164	112	0.013
positive regulation of cell migration	GO:0030335	2	0.013
peptide metabolic process	GO:0006518	80	0.013
tissue migration	GO:0090130	155	0.013
nucleotide metabolic process	GO:0009117	161	0.013
organophosphate catabolic process	GO:0046434	112	0.013
establishment or maintenance of cell polarity	GO:0007163	167	0.013
mating	GO:0007618	120	0.013
wound healing	GO:0042060	75	0.013
epithelial cell proliferation involved in renal tubule morphogenesis	GO:2001013	11	0.013
regulation of synaptic transmission	GO:0050804	69	0.013
tissue death	GO:0016271	102	0.013
protein catabolic process	GO:0030163	101	0.013
ribonucleotide catabolic process	GO:0009261	109	0.013
single organism cellular localization	GO:1902580	180	0.013
response to organonitrogen compound	GO:0010243	75	0.013
regulation of cellular catabolic process	GO:0031329	157	0.013
purine containing compound catabolic process	GO:0072523	112	0.013
regulation of cellular protein metabolic process	GO:0032268	243	0.013
regulation of protein modification process	GO:0031399	112	0.013
purine nucleotide metabolic process	GO:0006163	146	0.012
negative regulation of cell communication	GO:0010648	223	0.012
positive regulation of molecular function	GO:0044093	136	0.012
regulation of organ morphogenesis	GO:2000027	78	0.012
regulation of cell shape	GO:0008360	113	0.012
positive regulation of catalytic activity	GO:0043085	118	0.012
spinal cord development	GO:0021510	1	0.012
nucleoside triphosphate metabolic process	GO:0009141	120	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.012
aging	GO:0007568	143	0.012
ribonucleoside triphosphate catabolic process	GO:0009203	108	0.012
vitamin metabolic process	GO:0006766	2	0.012
transcription from rna polymerase ii promoter	GO:0006366	368	0.012
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.012
positive regulation of protein transport	GO:0051222	37	0.012
protein ubiquitination	GO:0016567	70	0.012
negative regulation of molecular function	GO:0044092	51	0.012
mitotic cell cycle phase transition	GO:0044772	138	0.012
dna integrity checkpoint	GO:0031570	81	0.012
neuron projection guidance	GO:0097485	241	0.012
cellular protein modification process	GO:0006464	438	0.012
regulation of establishment of protein localization	GO:0070201	61	0.012
photoreceptor cell differentiation	GO:0046530	170	0.012
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.012
positive regulation of nucleotide metabolic process	GO:0045981	55	0.012
regulation of defense response	GO:0031347	102	0.012
torso signaling pathway	GO:0008293	21	0.012
mesenchymal cell development	GO:0014031	1	0.012
adult behavior	GO:0030534	137	0.012
purine nucleoside catabolic process	GO:0006152	112	0.012
kidney development	GO:0001822	3	0.012
autophagy	GO:0006914	108	0.012
motor neuron axon guidance	GO:0008045	58	0.012
wing disc morphogenesis	GO:0007472	344	0.012
organic hydroxy compound metabolic process	GO:1901615	83	0.012
metal ion transport	GO:0030001	74	0.012
carbohydrate derivative catabolic process	GO:1901136	118	0.012
axis specification	GO:0009798	167	0.012
salivary gland cell autophagic cell death	GO:0035071	83	0.012
imaginal disc pattern formation	GO:0007447	91	0.012
salivary gland histolysis	GO:0035070	88	0.012
extrinsic apoptotic signaling pathway	GO:0097191	1	0.012
localization of cell	GO:0051674	257	0.012
outflow tract morphogenesis	GO:0003151	4	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
macromolecular complex assembly	GO:0065003	256	0.012
negative regulation of multicellular organismal process	GO:0051241	142	0.012
innate immune response activating signal transduction	GO:0002758	2	0.012
pattern recognition receptor signaling pathway	GO:0002221	2	0.012
protein transport	GO:0015031	155	0.011
camera type eye development	GO:0043010	4	0.011
nucleotide catabolic process	GO:0009166	109	0.011
positive regulation of transport	GO:0051050	92	0.011
stress activated protein kinase signaling cascade	GO:0031098	55	0.011
nephron tubule morphogenesis	GO:0072078	3	0.011
eye photoreceptor cell fate commitment	GO:0042706	37	0.011
taxis	GO:0042330	304	0.011
mitotic spindle organization	GO:0007052	220	0.011
hindgut development	GO:0061525	58	0.011
terminal region determination	GO:0007362	25	0.011
imaginal disc derived wing vein morphogenesis	GO:0008586	44	0.011
death	GO:0016265	284	0.011
positive regulation of proteolysis	GO:0045862	52	0.011
vitamin biosynthetic process	GO:0009110	1	0.011
sensory perception of smell	GO:0007608	80	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
cell projection assembly	GO:0030031	94	0.011
mitotic dna damage checkpoint	GO:0044773	74	0.011
cellular response to organic substance	GO:0071310	132	0.011
negative regulation of cell death	GO:0060548	81	0.011
glycosyl compound catabolic process	GO:1901658	112	0.011
axonogenesis	GO:0007409	290	0.011
response to alcohol	GO:0097305	95	0.011
response to oxygen containing compound	GO:1901700	200	0.011
protein modification by small protein conjugation	GO:0032446	79	0.011
dendrite morphogenesis	GO:0048813	199	0.011
autophagic cell death	GO:0048102	83	0.011
protein secretion	GO:0009306	45	0.011
limb development	GO:0060173	1	0.011
activation of innate immune response	GO:0002218	4	0.011
cell cycle arrest	GO:0007050	4	0.011
mesenchymal cell differentiation	GO:0048762	1	0.011
establishment of tissue polarity	GO:0007164	87	0.011
tracheal outgrowth open tracheal system	GO:0007426	18	0.011
apoptotic process	GO:0006915	159	0.011
cellular nitrogen compound catabolic process	GO:0044270	165	0.011
programmed cell death	GO:0012501	257	0.011
tube development	GO:0035295	244	0.011
peptidyl threonine phosphorylation	GO:0018107	2	0.011
chemotaxis	GO:0006935	249	0.011
anion homeostasis	GO:0055081	3	0.011
ribose phosphate metabolic process	GO:0019693	145	0.011
positive regulation of rna biosynthetic process	GO:1902680	266	0.011
response to extracellular stimulus	GO:0009991	116	0.010
erk1 and erk2 cascade	GO:0070371	39	0.010
olfactory behavior	GO:0042048	97	0.010
positive regulation of gene expression	GO:0010628	290	0.010
pigment metabolic process	GO:0042440	84	0.010
negative regulation of signaling	GO:0023057	219	0.010
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.010
regulation of localization	GO:0032879	275	0.010
purine ribonucleoside metabolic process	GO:0046128	127	0.010
mitotic cell cycle checkpoint	GO:0007093	88	0.010
regulation of epidermal growth factor activated receptor activity	GO:0007176	4	0.010
cellular response to ethanol	GO:0071361	4	0.010
heterocycle catabolic process	GO:0046700	166	0.010
single organismal cell cell adhesion	GO:0016337	45	0.010
glycosyl compound metabolic process	GO:1901657	127	0.010
cytoskeleton dependent cytokinesis	GO:0061640	81	0.010
cognition	GO:0050890	141	0.010
g2 dna damage checkpoint	GO:0031572	69	0.010
negative regulation of cellular component organization	GO:0051129	108	0.010
response to heat	GO:0009408	63	0.010

yellow-g disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.042
vascular disease	DOID:178	0.025
hypertension	DOID:10763	0.025
artery disease	DOID:0050828	0.025
cardiovascular system disease	DOID:1287	0.025
disease of metabolism	DOID:0014667	0.016
nervous system disease	DOID:863	0.015
acquired metabolic disease	DOID:0060158	0.014
inherited metabolic disorder	DOID:655	0.013

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network