Drosophila melanogaster

122 known processes

Sh (Dmel_CG12348)

Shaker

(Aliases: EKO,Dmel\CG12348,Sha,Shw,BcDNA:GH03046,V-I,SH,sh,CG17860,CG12348,CG7640,F-c,minisleep)

Sh biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transportGO:00068111450.489
cation transportGO:00068121100.423
cation transmembrane transportGO:0098655880.421
locomotory behaviorGO:00076261760.363
ion transmembrane transportGO:00342201220.292
response to abiotic stimulusGO:00096283410.167
synaptic transmissionGO:00072682880.158
learningGO:0007612750.154
response to organic substanceGO:00100332840.143
Rat
adult behaviorGO:00305341370.138
single organism behaviorGO:00447083910.136
synapse organizationGO:00508081960.130
transmembrane transportGO:00550851390.129
establishment of localization in cellGO:00516494020.125
metal ion transportGO:0030001740.109
Human Mouse Rat Fly
adult locomotory behaviorGO:0008344760.107
associative learningGO:0008306650.104
sensory organ morphogenesisGO:00905962600.100
axonogenesisGO:00074092900.093
sleepGO:0030431490.091
monovalent inorganic cation transportGO:0015672400.085
Human Mouse Rat Fly
neurological system processGO:00508773580.083
inorganic cation transmembrane transportGO:0098662610.082
Human Mouse Rat Fly
eye developmentGO:00016543230.077
telencephalon developmentGO:002153720.076
compound eye developmentGO:00487493070.075
learning or memoryGO:00076111410.072
cognitionGO:00508901410.071
neuromuscular synaptic transmissionGO:0007274670.068
eye morphogenesisGO:00485922600.061
protein complex biogenesisGO:00702712010.060
Rat
forebrain developmentGO:003090020.060
response to light stimulusGO:00094161240.059
regulation of excitatory postsynaptic membrane potentialGO:006007930.058
regulation of synaptic transmissionGO:0050804690.055
cellular response to nutrient levelsGO:0031669620.050
homeostatic processGO:00425921990.050
Rat
response to other organismGO:00517072930.048
protein localizationGO:00081042840.048
cellular response to lipopolysaccharideGO:007122230.046
endocytosisGO:00068973100.045
cell adhesionGO:00071551360.044
circulatory system developmentGO:0072359820.043
response to external biotic stimulusGO:00432072930.042
response to sterolGO:0036314340.041
negative regulation of cellular metabolic processGO:00313243820.039
muscle structure developmentGO:00610612240.038
developmental growthGO:00485892800.037
anatomical structure homeostasisGO:0060249970.037
protein complex assemblyGO:00064612000.037
Rat
axon developmentGO:00615642970.037
photoreceptor cell differentiationGO:00465301700.036
response to lipopolysaccharideGO:003249640.036
cellular response to chemical stimulusGO:00708871990.036
organonitrogen compound metabolic processGO:19015643180.035
cellular response to dna damage stimulusGO:00069742230.035
dna metabolic processGO:00062592270.035
response to alkaloidGO:0043279260.035
eye photoreceptor cell differentiationGO:00017541450.034
central nervous system developmentGO:00074172010.033
vesicle mediated transportGO:00161923810.033
response to alcoholGO:0097305950.033
protein heterooligomerizationGO:005129140.033
cellular response to molecule of bacterial originGO:007121930.033
flight behaviorGO:0007629260.033
regulation of membrane potentialGO:0042391350.032
membrane depolarizationGO:005189940.032
cellular homeostasisGO:0019725800.032
Rat
eye photoreceptor cell developmentGO:0042462810.032
circadian sleep wake cycle processGO:0022410240.032
dna repairGO:0006281540.031
regulation of nervous system developmentGO:00519602480.031
response to insecticideGO:0017085140.031
inorganic ion transmembrane transportGO:0098660730.031
Human Mouse Rat Fly
transcription from rna polymerase ii promoterGO:00063663680.030
dendrite developmentGO:00163582040.030
regulation of molecular functionGO:00650092170.030
circadian sleep wake cycleGO:0042745280.029
circadian behaviorGO:0048512760.029
single organism biosynthetic processGO:00447112060.029
cellular response to biotic stimulusGO:007121640.029
positive regulation of biosynthetic processGO:00098913160.028
dendrite morphogenesisGO:00488131990.028
macromolecular complex assemblyGO:00650032560.028
Rat
sensory perception of chemical stimulusGO:00076061160.028
potassium ion transportGO:0006813200.028
Human Mouse Rat Fly
heart developmentGO:0007507820.028
neuron recognitionGO:00080381010.027
muscle organ developmentGO:00075171270.027
circadian sleep wake cycle sleepGO:0050802230.027
response to nitrogen compoundGO:1901698900.027
compound eye morphogenesisGO:00017452490.027
organic substance transportGO:00717022570.027
response to oxygen containing compoundGO:19017002000.026
Rat
cellular response to organic substanceGO:00713101320.025
mrna processingGO:00063971040.025
phagocytosisGO:00069092150.025
response to organonitrogen compoundGO:0010243750.025
axon guidanceGO:00074112330.024
positive regulation of rna biosynthetic processGO:19026802660.024
response to toxic substanceGO:0009636220.024
establishment of protein localizationGO:00451841630.024
rhythmic processGO:00485111060.024
muscle contractionGO:0006936130.024
response to decreased oxygen levelsGO:0036293580.023
Rat
brain developmentGO:00074201200.023
response to endogenous stimulusGO:00097191190.023
nuclear divisionGO:00002803320.023
behavioral response to ethanolGO:0048149490.022
imaginal disc derived wing morphogenesisGO:00074763370.022
biological adhesionGO:00226101380.022
membrane organizationGO:00610241120.022
regulation of phosphorylationGO:00423251470.022
response to oxidative stressGO:0006979860.021
Rat
regulation of multicellular organismal developmentGO:20000264140.021
regulation of localizationGO:00328792750.021
negative regulation of developmental processGO:00510932010.021
organelle fissionGO:00482853400.021
single organism membrane organizationGO:0044802930.020
regulation of cell cycleGO:00517262910.020
Rat
positive regulation of macromolecule biosynthetic processGO:00105572830.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
divalent metal ion transportGO:0070838260.020
striated muscle cell differentiationGO:0051146900.020
regulation of ion transportGO:0043269390.020
regulation of transportGO:00510491810.020
positive regulation of cellular biosynthetic processGO:00313283160.020
protein transportGO:00150311550.020
oxoacid metabolic processGO:00434361030.019
agingGO:00075681430.019
molting cycleGO:0042303560.019
regulation of secretionGO:0051046440.019
establishment or maintenance of cell polarityGO:00071631670.019
response to organic cyclic compoundGO:0014070890.019
posttranscriptional regulation of gene expressionGO:00106081450.019
negative regulation of response to stimulusGO:00485852580.019
developmental maturationGO:00217001720.019
regulation of neuron differentiationGO:00456641030.019
regulation of developmental growthGO:00486381740.018
memoryGO:0007613940.018
meiotic cell cycleGO:00513211710.018
secretionGO:00469031090.018
chemotaxisGO:00069352490.018
photoreceptor cell developmentGO:0042461960.018
rna processingGO:00063961470.018
regulation of cellular localizationGO:00603411360.018
carboxylic acid metabolic processGO:0019752920.018
response to bacteriumGO:00096171980.018
response to oxygen levelsGO:0070482590.018
Rat
cell recognitionGO:00080371020.018
regulation of protein metabolic processGO:00512462560.018
kidney developmentGO:000182230.018
regulation of alternative mrna splicing via spliceosomeGO:0000381600.018
compound eye photoreceptor developmentGO:0042051780.017
body morphogenesisGO:001017120.017
negative regulation of gene expressionGO:00106293870.017
negative regulation of cellular protein metabolic processGO:0032269850.017
oocyte constructionGO:00073081120.017
appendage developmentGO:00487364010.017
programmed cell deathGO:00125012570.017
response to nutrient levelsGO:00316671140.017
axis specificationGO:00097981670.017
synaptic growth at neuromuscular junctionGO:00511241190.016
positive regulation of gene expressionGO:00106282900.016
cellular response to external stimulusGO:0071496660.016
appendage morphogenesisGO:00351073970.016
negative regulation of signalingGO:00230572190.016
carbohydrate derivative metabolic processGO:19011352170.015
regulation of cell differentiationGO:00455953020.015
positive regulation of cell communicationGO:00106472500.015
antimicrobial humoral responseGO:0019730990.015
skeletal muscle organ developmentGO:0060538480.015
hindbrain developmentGO:003090220.015
enzyme linked receptor protein signaling pathwayGO:00071671790.015
intracellular transportGO:00469072280.015
regulation of mrna metabolic processGO:1903311720.015
regulation of phosphate metabolic processGO:00192202100.015
cellular response to decreased oxygen levelsGO:0036294300.015
camera type eye developmentGO:004301040.015
cellular response to starvationGO:0009267610.015
segmentationGO:00352822070.014
secretion by cellGO:00329401010.014
multi multicellular organism processGO:00447061230.014
cell maturationGO:00484691440.014
regulation of neuron projection developmentGO:0010975690.014
regulation of secretion by cellGO:1903530390.014
regulation of cellular amino acid metabolic processGO:000652100.014
organic acid metabolic processGO:00060821030.014
response to ethanolGO:0045471590.014
tube developmentGO:00352952440.014
organic substance catabolic processGO:19015753080.014
compound eye photoreceptor cell differentiationGO:00017511400.014
neurotransmitter secretionGO:0007269350.014
phosphorylationGO:00163102940.014
multicellular organismal signalingGO:0035637120.014
Human
cellular protein modification processGO:00064644380.014
transmission of nerve impulseGO:0019226120.014
negative regulation of rna biosynthetic processGO:19026792400.013
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.013
negative regulation of notch signaling pathwayGO:0045746410.013
positive regulation of rna metabolic processGO:00512542710.013
cell deathGO:00082192790.013
regulation of mitotic cell cycleGO:00073461900.013
Rat
regulation of cellular ketone metabolic processGO:001056530.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
muscle system processGO:0003012210.013
taxisGO:00423303040.013
negative regulation of insulin secretionGO:004667610.013
embryonic development via the syncytial blastodermGO:00017001480.013
positive regulation of exocytosisGO:004592140.013
carbohydrate derivative biosynthetic processGO:1901137850.013
organonitrogen compound biosynthetic processGO:19015661170.013
regulation of growthGO:00400082330.013
microtubule organizing center organizationGO:00310231680.013
negative regulation of rna metabolic processGO:00512532510.013
cell divisionGO:00513012480.013
chemosensory behaviorGO:00076351060.013
intracellular signal transductionGO:00355563000.013
regulation of mrna processingGO:0050684710.012
regulation of catalytic activityGO:00507901850.012
chemical homeostasisGO:0048878920.012
Rat
embryo development ending in birth or egg hatchingGO:00097921520.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
regulation of cellular amine metabolic processGO:003323830.012
negative regulation of signal transductionGO:00099682060.012
regulation of cellular component sizeGO:0032535980.012
regulation of transmembrane transportGO:0034762270.012
catabolic processGO:00090564090.012
amine metabolic processGO:0009308120.012
calcium ion transportGO:0006816240.012
embryonic pattern specificationGO:00098801740.012
muscle fiber developmentGO:0048747120.012
response to organophosphorusGO:004668320.012
spinal cord developmentGO:002151010.012
mitotic nuclear divisionGO:00070672130.012
positive regulation of signalingGO:00230562430.012
tripartite regional subdivisionGO:00073511030.012
head developmentGO:00603221350.012
neuron neuron synaptic transmissionGO:0007270140.012
oocyte axis specificationGO:00073091080.012
mrna splicing via spliceosomeGO:0000398730.012
growthGO:00400073590.012
regulation of cellular protein metabolic processGO:00322682430.012
cellular amino acid metabolic processGO:0006520610.012
sensory perceptionGO:00076001960.012
regulation of response to stressGO:00801342000.012
cellular response to carbohydrate stimulusGO:007132240.011
cytokinesisGO:0000910900.011
purine containing compound metabolic processGO:00725211550.011
anterior posterior axis specificationGO:00099481090.011
molting cycle processGO:0022404290.011
regionalizationGO:00030024160.011
g protein coupled receptor signaling pathwayGO:00071861360.011
post embryonic appendage morphogenesisGO:00351203850.011
retina development in camera type eyeGO:006004140.011
notch signaling pathwayGO:00072191200.011
potassium ion transmembrane transportGO:0071805180.011
Human Mouse Rat Fly
positive regulation of molecular functionGO:00440931360.011
synaptic transmission cholinergicGO:000727190.011
organic cyclic compound catabolic processGO:19013611680.011
multicellular organism growthGO:0035264460.011
regulation of synapse assemblyGO:0051963940.011
erbb signaling pathwayGO:0038127580.011
synaptic vesicle localizationGO:0097479530.011
sodium ion transportGO:0006814220.011
response to woundingGO:0009611940.011
ribose phosphate metabolic processGO:00196931450.011
negative regulation of homeostatic processGO:003284520.011
rna splicing via transesterification reactionsGO:0000375730.011
regulation of antimicrobial peptide biosynthetic processGO:0002805380.011
mitotic cytokinesisGO:0000281500.011
olfactory behaviorGO:0042048970.011
multi organism behaviorGO:00517051750.011
negative regulation of cellular biosynthetic processGO:00313272770.011
wing disc morphogenesisGO:00074723440.011
gravitaxisGO:0042332260.011
single organism catabolic processGO:00447122280.011
macromolecule catabolic processGO:00090571610.010
nucleoside phosphate metabolic processGO:00067531620.010
mrna metabolic processGO:00160711240.010
imaginal disc derived wing margin morphogenesisGO:0008587410.010
establishment of vesicle localizationGO:0051650510.010
positive regulation of nitrogen compound metabolic processGO:00511733540.010
response to radiationGO:00093141550.010
asymmetric stem cell divisionGO:0098722490.010
rna localizationGO:00064031150.010
sensory perception of smellGO:0007608800.010
cellular ketone metabolic processGO:0042180240.010
regulation of cell cycle processGO:00105641810.010
Rat
inositol lipid mediated signalingGO:004801740.010

Sh disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.024
Human
nervous system diseaseDOID:86300.013
Human
disease of metabolismDOID:001466700.011
acquired metabolic diseaseDOID:006015800.011