Drosophila melanogaster

25 known processes

Gem3 (Dmel_CG6539)

Gemin3

(Aliases: Dmel\CG6539,BcDNA:LD05563,CG6539,dGem3,Dhh1,DHH1,l(3)rL562,BcDNA.LD05563,DmRH22)

Gem3 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
open tracheal system developmentGO:00074242040.601
regulation of synaptic growth at neuromuscular junctionGO:0008582890.484
locomotory behaviorGO:00076261760.408
regulation of developmental growthGO:00486381740.394
single organism behaviorGO:00447083910.369
adult locomotory behaviorGO:0008344760.325
synaptic transmissionGO:00072682880.306
muscle structure developmentGO:00610612240.285
cell maturationGO:00484691440.235
response to alcoholGO:0097305950.230
regulation of cellular component biogenesisGO:00440872010.225
homeostatic processGO:00425921990.215
negative regulation of cellular component organizationGO:00511291080.205
reproductive behaviorGO:00190981220.201
mitochondrion organizationGO:0007005650.201
cellular response to dna damage stimulusGO:00069742230.191
regulation of multicellular organismal developmentGO:20000264140.181
adult behaviorGO:00305341370.178
regulation of synapse assemblyGO:0051963940.170
organonitrogen compound metabolic processGO:19015643180.165
growthGO:00400073590.156
synapse organizationGO:00508081960.156
ion transportGO:00068111450.156
columnar cuboidal epithelial cell developmentGO:00020662490.155
neuromuscular junction developmentGO:00075281490.147
negative regulation of synapse assemblyGO:0051964390.131
negative regulation of multicellular organismal processGO:00512411420.130
mating behaviorGO:00076171060.128
rna polyadenylationGO:0043631120.123
regulation of peptidase activityGO:0052547390.119
compound eye photoreceptor cell differentiationGO:00017511400.115
regulation of organelle organizationGO:00330431960.113
regulation of nervous system developmentGO:00519602480.112
negative regulation of nervous system developmentGO:0051961920.102
negative regulation of developmental processGO:00510932010.100
protein modification by small protein conjugation or removalGO:00706471060.099
synaptic growth at neuromuscular junctionGO:00511241190.098
positive regulation of signal transductionGO:00099672230.098
negative regulation of cell cycle phase transitionGO:19019881030.095
regulation of cell differentiationGO:00455953020.094
response to temperature stimulusGO:00092661060.093
mitotic g2 dna damage checkpointGO:0007095690.092
positive regulation of response to stimulusGO:00485843230.091
regulation of synapse organizationGO:00508071100.088
regulation of notch signaling pathwayGO:00085931000.086
regulation of protein complex disassemblyGO:0043244290.085
mitotic nuclear divisionGO:00070672130.085
cytoplasmic transportGO:00164821300.085
cellular response to abiotic stimulusGO:0071214580.084
response to abiotic stimulusGO:00096283410.081
male mating behaviorGO:0060179700.081
cellular protein modification processGO:00064644380.080
developmental growthGO:00485892800.078
dna repairGO:0006281540.078
developmental maturationGO:00217001720.077
compound eye morphogenesisGO:00017452490.074
negative regulation of cell cycleGO:00457861160.073
synapse assemblyGO:00074161430.071
positive regulation of developmental growthGO:0048639620.070
regulation of growthGO:00400082330.068
transcription from rna polymerase ii promoterGO:00063663680.066
Mouse
taxisGO:00423303040.065
negative regulation of response to stimulusGO:00485852580.063
notch signaling pathwayGO:00072191200.062
organelle fissionGO:00482853400.062
positive regulation of biosynthetic processGO:00098913160.060
sensory organ morphogenesisGO:00905962600.059
regulation of molecular functionGO:00650092170.059
response to radiationGO:00093141550.059
morphogenesis of an epitheliumGO:00020092760.058
protein polymerizationGO:0051258420.057
macromolecular complex assemblyGO:00650032560.056
divalent inorganic cation transportGO:0072511300.056
positive regulation of nucleic acid templated transcriptionGO:19035082660.056
small molecule metabolic processGO:00442813050.056
positive regulation of signalingGO:00230562430.055
central nervous system developmentGO:00074172010.055
mitotic cell cycle phase transitionGO:00447721380.054
response to organic cyclic compoundGO:0014070890.053
regulation of mitotic cell cycleGO:00073461900.052
chromosome organizationGO:00512763600.052
proteolysisGO:00065081920.052
positive regulation of cell communicationGO:00106472500.051
regulation of cellular protein metabolic processGO:00322682430.050
nitrogen compound transportGO:0071705850.049
wing disc morphogenesisGO:00074723440.048
ubiquitin dependent protein catabolic processGO:0006511780.048
protein modification by small protein conjugationGO:0032446790.048
negative regulation of mitotic cell cycle phase transitionGO:19019911030.047
cellular catabolic processGO:00442483720.047
regulation of synapse structure and activityGO:00508031280.046
multi organism behaviorGO:00517051750.046
response to ecdysoneGO:0035075340.046
imaginal disc fusionGO:0046528190.046
neuromuscular synaptic transmissionGO:0007274670.045
intracellular signal transductionGO:00355563000.045
negative regulation of nucleobase containing compound metabolic processGO:00459342610.044
Mouse
mrna polyadenylationGO:0006378110.044
regulation of mitotic cell cycle phase transitionGO:19019901300.042
positive regulation of multicellular organismal processGO:00512401430.042
positive regulation of cellular component organizationGO:00511301560.042
cation transportGO:00068121100.041
catabolic processGO:00090564090.041
response to inorganic substanceGO:0010035440.041
regulation of proteolysisGO:0030162870.040
head developmentGO:00603221350.039
dna metabolic processGO:00062592270.039
eye morphogenesisGO:00485922600.038
positive regulation of nitrogen compound metabolic processGO:00511733540.038
metal ion transportGO:0030001740.038
embryo development ending in birth or egg hatchingGO:00097921520.038
carbohydrate derivative metabolic processGO:19011352170.037
organic substance transportGO:00717022570.037
epithelial cell differentiationGO:00308553220.036
positive regulation of rna biosynthetic processGO:19026802660.036
ovarian follicle cell developmentGO:00307072480.036
regulation of transcription from rna polymerase ii promoterGO:00063573780.035
Mouse
single organism biosynthetic processGO:00447112060.035
Mouse
positive regulation of developmental processGO:00510941430.035
protein ubiquitinationGO:0016567700.035
epithelial cell developmentGO:00020642740.034
regulation of phosphatase activityGO:001092130.034
neuron projection guidanceGO:00974852410.033
brain developmentGO:00074201200.033
intracellular transportGO:00469072280.033
actin filament organizationGO:00070151260.033
striated muscle myosin thick filament assemblyGO:007168830.033
regulation of cytoplasmic transportGO:1903649470.032
rna localizationGO:00064031150.032
negative regulation of macromolecule biosynthetic processGO:00105582700.032
Mouse
actin cytoskeleton organizationGO:00300362060.031
segmentationGO:00352822070.030
ribose phosphate metabolic processGO:00196931450.030
regulation of anatomical structure morphogenesisGO:00226032420.030
purine ribonucleotide metabolic processGO:00091501450.030
multi organism reproductive behaviorGO:00447051210.029
regulation of catalytic activityGO:00507901850.029
nucleocytoplasmic transportGO:0006913720.029
regulation of cell developmentGO:00602842150.029
ecdysone receptor mediated signaling pathwayGO:0035076110.028
regulation of intracellular transportGO:0032386640.028
chromatin silencingGO:0006342760.028
negative regulation of rna biosynthetic processGO:19026792400.028
Mouse
single organism catabolic processGO:00447122280.028
transmembrane transportGO:00550851390.028
peptidyl lysine methylationGO:0018022160.028
actin filament based processGO:00300292200.027
muscle cell differentiationGO:00426921030.027
positive regulation of multicellular organism growthGO:0040018210.027
gene silencingGO:00164581380.026
nuclear exportGO:0051168240.025
carbohydrate derivative biosynthetic processGO:1901137850.025
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.024
Mouse
regulation of protein metabolic processGO:00512462560.024
oocyte constructionGO:00073081120.024
regulation of cell cycle processGO:00105641810.023
regulation of cell shapeGO:00083601130.023
striated muscle cell differentiationGO:0051146900.023
negative regulation of mitotic cell cycleGO:00459301090.023
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.023
cellular cation homeostasisGO:0030003380.023
protein modification processGO:00362114380.022
chromatin organizationGO:00063252070.022
positive regulation of nucleobase containing compound metabolic processGO:00459353320.022
response to light stimulusGO:00094161240.022
negative regulation of notch signaling pathwayGO:0045746410.022
signal transduction in response to dna damageGO:004277030.022
tissue morphogenesisGO:00487292970.021
oocyte axis specificationGO:00073091080.021
regulation of programmed cell deathGO:00430671520.021
Mouse
mrna transportGO:0051028150.021
spermatogenesisGO:00072832000.021
negative regulation of nitrogen compound metabolic processGO:00511722650.021
Mouse
regulation of hydrolase activityGO:0051336970.021
regulation of dna metabolic processGO:0051052340.021
compound eye developmentGO:00487493070.021
tissue deathGO:00162711020.020
response to sterolGO:0036314340.020
positive regulation of macromolecule metabolic processGO:00106044050.020
mitotic cell cycle checkpointGO:0007093880.020
rhythmic processGO:00485111060.019
rna transportGO:0050658460.019
positive regulation of macromolecule biosynthetic processGO:00105572830.019
regulation of cell cycleGO:00517262910.019
regionalizationGO:00030024160.019
cell cycle phase transitionGO:00447701400.019
axon developmentGO:00615642970.019
chromosome segregationGO:00070591570.019
response to ketoneGO:1901654340.019
regulation of gene expression epigeneticGO:00400291280.019
modification dependent macromolecule catabolic processGO:0043632790.019
chemical homeostasisGO:0048878920.019
metal ion homeostasisGO:0055065440.019
positive regulation of apoptotic signaling pathwayGO:200123540.019
nuclear envelope organizationGO:000699870.019
negative regulation of cell cycle processGO:00109481090.019
cellular component assembly involved in morphogenesisGO:00109271510.018
appendage developmentGO:00487364010.018
microtubule organizing center organizationGO:00310231680.018
negative regulation of neuroblast proliferationGO:0007406270.018
regulation of phosphate metabolic processGO:00192202100.018
regulation of protein catabolic processGO:0042176550.018
establishment of rna localizationGO:0051236470.018
negative regulation of growthGO:0045926840.018
embryonic pattern specificationGO:00098801740.017
positive regulation of mitotic sister chromatid separationGO:1901970100.017
carbohydrate metabolic processGO:0005975820.017
regulation of neuroblast proliferationGO:1902692340.017
actin polymerization or depolymerizationGO:0008154310.017
negative regulation of gene expressionGO:00106293870.017
Mouse
negative regulation of proteolysisGO:0045861310.016
response to heatGO:0009408630.016
anatomical structure homeostasisGO:0060249970.016
myofibril assemblyGO:0030239360.016
formation of anatomical boundaryGO:0048859370.016
regulation of cell cycle phase transitionGO:19019871300.016
ncrna metabolic processGO:0034660430.016
blastoderm segmentationGO:00073501590.016
cellular amino acid metabolic processGO:0006520610.016
eye photoreceptor cell differentiationGO:00017541450.016
vesicle mediated transportGO:00161923810.016
Worm
eggshell formationGO:00307031050.016
eye developmentGO:00016543230.016
cellular metal ion homeostasisGO:0006875310.016
morphogenesis of a polarized epitheliumGO:0001738930.016
protein complex assemblyGO:00064612000.015
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.015
embryonic axis specificationGO:00005781070.015
negative regulation of cellular biosynthetic processGO:00313272770.015
Mouse
larval locomotory behaviorGO:0008345270.015
wound healingGO:0042060750.015
larval developmentGO:00021641040.015
cellular protein complex assemblyGO:0043623710.015
appendage morphogenesisGO:00351073970.015
cellular response to chemical stimulusGO:00708871990.014
negative regulation of defense responseGO:0031348350.014
maintenance of locationGO:0051235730.014
positive regulation of transcription dna templatedGO:00458932660.014
tube morphogenesisGO:00352391910.014
oocyte maturationGO:000155630.014
regulation of phosphorus metabolic processGO:00511742100.014
negative regulation of signalingGO:00230572190.014
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.014
Mouse
rhabdomere developmentGO:0042052380.014
cellular macromolecular complex assemblyGO:00346221530.014
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.014
proteasomal protein catabolic processGO:0010498590.014
regulation of anatomical structure sizeGO:00900661630.014
dna templated transcription elongationGO:0006354180.013
phagocytosisGO:00069092150.013
protein transportGO:00150311550.013
negative regulation of biosynthetic processGO:00098902770.013
Mouse
regulation of nucleocytoplasmic transportGO:0046822350.013
regulation of cellular component sizeGO:0032535980.013
molting cycle chitin based cuticleGO:0007591560.013
regulation of localizationGO:00328792750.013
cellular response to organic cyclic compoundGO:0071407320.013
dna double strand break processingGO:000072930.013
connective tissue developmentGO:006144830.013
positive regulation of growthGO:0045927750.013
cell proliferationGO:00082832990.013
regulation of actin polymerization or depolymerizationGO:0008064270.012
regulation of protein modification processGO:00313991120.012
multicellular organismal agingGO:00102591400.012
axon guidanceGO:00074112330.012
agingGO:00075681430.012
cellular lipid metabolic processGO:0044255830.012
feeding behaviorGO:0007631500.012
single organism intracellular transportGO:19025822070.012
chromatin modificationGO:00165681470.012
spermatid developmentGO:0007286980.011
positive regulation of catalytic activityGO:00430851180.011
negative regulation of cellular metabolic processGO:00313243820.011
Mouse
protein processingGO:0016485680.011
peripheral nervous system developmentGO:0007422520.011
cellular response to sterol depletionGO:007150130.011
ribonucleotide metabolic processGO:00092591450.011
single organism carbohydrate metabolic processGO:0044723720.011
purine nucleoside monophosphate catabolic processGO:0009128380.011
mitotic g2 m transition checkpointGO:0044818700.011
neuron remodelingGO:0016322290.011
ribonucleoside metabolic processGO:00091191270.011
mitotic sister chromatid segregationGO:0000070870.011
divalent metal ion transportGO:0070838260.011
calcium ion homeostasisGO:0055074230.011
nuclear importGO:0051170510.011
nucleoside monophosphate metabolic processGO:0009123520.010
single organism cellular localizationGO:19025801800.010
nuclear transportGO:0051169720.010
regulation of multicellular organism growthGO:0040014400.010
nucleoside monophosphate catabolic processGO:0009125390.010
establishment of tissue polarityGO:0007164870.010
regulation of ion transportGO:0043269390.010
actin filament polymerizationGO:0030041270.010
glycoprotein metabolic processGO:0009100410.010
larval behaviorGO:0030537420.010
sarcomere organizationGO:0045214260.010
cellular protein catabolic processGO:0044257830.010
negative regulation of cell communicationGO:00106482230.010

Gem3 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.080
nervous system diseaseDOID:86300.033
central nervous system diseaseDOID:33100.014
neurodegenerative diseaseDOID:128900.010