Drosophila melanogaster

37 known processes

Trxr-1 (Dmel_CG2151)

Thioredoxin reductase-1

(Aliases: gr,l(1)G0379,Dmel\CG2151,DTR,dmtrxr-1,TrxR,DmTrxR,CG2151,l(1)G0154,l(1)G0481,TrxR-1,2151,Trxr1,trxr-1,DmTrxR-1,GR,Trx,l(1)G0477,anon-WO03040301.185,anon-WO03040301.187,Gr,DmTR)

Trxr-1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
spermatid differentiationGO:00485151140.838
response to extracellular stimulusGO:00099911160.779
cytoplasmic microtubule organizationGO:0031122220.727
deathGO:00162652840.609
muscle cell differentiationGO:00426921030.590
positive regulation of cysteine type endopeptidase activityGO:2001056240.584
spermatid developmentGO:0007286980.552
response to nutrient levelsGO:00316671140.495
imaginal disc derived appendage developmentGO:00487373990.489
organonitrogen compound metabolic processGO:19015643180.485
response to oxidative stressGO:0006979860.447
regulation of cell deathGO:00109411730.440
determination of adult lifespanGO:00083401370.414
striated muscle cell differentiationGO:0051146900.378
small molecule metabolic processGO:00442813050.367
multicellular organismal agingGO:00102591400.363
male gamete generationGO:00482322010.359
carboxylic acid metabolic processGO:0019752920.342
spermatogenesisGO:00072832000.321
negative regulation of nitrogen compound metabolic processGO:00511722650.304
cell deathGO:00082192790.294
protein localizationGO:00081042840.260
cellular component assembly involved in morphogenesisGO:00109271510.254
homeostatic processGO:00425921990.240
positive regulation of proteolysisGO:0045862520.227
regulation of protein metabolic processGO:00512462560.215
cellular catabolic processGO:00442483720.207
regulation of gene expression epigeneticGO:00400291280.206
positive regulation of response to stimulusGO:00485843230.205
regulation of notch signaling pathwayGO:00085931000.205
programmed cell deathGO:00125012570.199
positive regulation of macromolecule metabolic processGO:00106044050.193
positive regulation of endopeptidase activityGO:0010950260.192
single organism catabolic processGO:00447122280.186
muscle cell developmentGO:0055001500.186
negative regulation of signalingGO:00230572190.183
negative regulation of nucleobase containing compound metabolic processGO:00459342610.183
positive regulation of nitrogen compound metabolic processGO:00511733540.181
positive regulation of signalingGO:00230562430.181
apoptotic processGO:00069151590.179
amine metabolic processGO:0009308120.176
positive regulation of cell communicationGO:00106472500.174
positive regulation of nucleobase containing compound metabolic processGO:00459353320.174
positive regulation of macromolecule biosynthetic processGO:00105572830.165
positive regulation of cellular biosynthetic processGO:00313283160.157
glycosyl compound catabolic processGO:19016581120.155
vesicle mediated transportGO:00161923810.152
positive regulation of cellular protein metabolic processGO:00322701180.150
nucleotide metabolic processGO:00091171610.133
wing disc morphogenesisGO:00074723440.132
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.132
organic substance catabolic processGO:19015753080.131
appendage developmentGO:00487364010.130
positive regulation of cell deathGO:0010942690.129
striated muscle myosin thick filament assemblyGO:007168830.127
actin filament based processGO:00300292200.126
chromosome segregationGO:00070591570.125
regulation of cellular protein metabolic processGO:00322682430.121
pigmentationGO:0043473750.121
regulation of cell morphogenesisGO:00226041630.120
striated muscle cell developmentGO:0055002500.120
positive regulation of signal transductionGO:00099672230.120
regulation of programmed cell deathGO:00430671520.119
circulatory system developmentGO:0072359820.118
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.115
negative regulation of macromolecule biosynthetic processGO:00105582700.115
protein modification processGO:00362114380.112
carbohydrate biosynthetic processGO:0016051170.112
agingGO:00075681430.111
cellular protein modification processGO:00064644380.109
positive regulation of programmed cell deathGO:0043068620.107
meiotic cell cycleGO:00513211710.106
cellular response to chemical stimulusGO:00708871990.105
acyl coa metabolic processGO:000663730.104
negative regulation of growthGO:0045926840.104
trna aminoacylation for protein translationGO:000641820.102
positive regulation of gene expressionGO:00106282900.101
imaginal disc derived appendage morphogenesisGO:00351143950.098
regulation of apoptotic processGO:00429811300.098
single organism biosynthetic processGO:00447112060.097
anatomical structure homeostasisGO:0060249970.095
aromatic compound catabolic processGO:00194391660.095
negative regulation of cellular metabolic processGO:00313243820.094
appendage morphogenesisGO:00351073970.094
organelle assemblyGO:00709251980.093
ion transportGO:00068111450.093
growthGO:00400073590.093
positive regulation of cell migrationGO:003033520.093
regulation of cysteine type endopeptidase activityGO:2000116270.092
microvillus organizationGO:003252840.091
cellular response to dna damage stimulusGO:00069742230.090
pupal developmentGO:0035209110.090
nuclear divisionGO:00002803320.088
negative regulation of cellular biosynthetic processGO:00313272770.087
nucleoside phosphate metabolic processGO:00067531620.087
developmental growthGO:00485892800.087
negative regulation of rna metabolic processGO:00512532510.087
nucleotide catabolic processGO:00091661090.086
oxoacid metabolic processGO:00434361030.085
regulation of cellular ketone metabolic processGO:001056530.084
proteolysisGO:00065081920.082
cellular response to extracellular stimulusGO:0031668640.080
cellular response to external stimulusGO:0071496660.079
gene silencingGO:00164581380.078
actin cytoskeleton organizationGO:00300362060.078
phosphorylationGO:00163102940.076
regulation of developmental growthGO:00486381740.075
myofibril assemblyGO:0030239360.074
dna metabolic processGO:00062592270.074
axonogenesisGO:00074092900.073
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.073
negative regulation of rna biosynthetic processGO:19026792400.073
muscle structure developmentGO:00610612240.073
tube developmentGO:00352952440.072
glycosyl compound metabolic processGO:19016571270.071
cell projection assemblyGO:0030031940.069
response to monosaccharideGO:003428440.068
regulation of endopeptidase activityGO:0052548360.068
heart developmentGO:0007507820.068
regulation of localizationGO:00328792750.068
regulation of cell proliferationGO:00421271630.067
respiratory system developmentGO:00605412130.066
regulation of cellular amine metabolic processGO:003323830.066
digestive tract morphogenesisGO:00485461270.066
positive regulation of transcription dna templatedGO:00458932660.065
positive regulation of peptidase activityGO:0010952290.064
head developmentGO:00603221350.064
regulation of cellular amino acid metabolic processGO:000652100.064
catabolic processGO:00090564090.064
organonitrogen compound biosynthetic processGO:19015661170.064
positive regulation of rna biosynthetic processGO:19026802660.064
negative regulation of transcription dna templatedGO:00458922370.063
meiotic nuclear divisionGO:00071261510.063
negative regulation of cell proliferationGO:0008285690.060
nucleoside metabolic processGO:00091161270.060
nucleobase containing small molecule metabolic processGO:00550861740.059
purine nucleoside catabolic processGO:00061521120.059
rhythmic processGO:00485111060.058
organic acid metabolic processGO:00060821030.057
autophagyGO:00069141080.056
regulation of growthGO:00400082330.056
ribose phosphate metabolic processGO:00196931450.055
adherens junction organizationGO:0034332270.055
establishment of protein localizationGO:00451841630.055
dendrite morphogenesisGO:00488131990.054
intracellular signal transductionGO:00355563000.054
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.054
regulation of intracellular signal transductionGO:19025312360.053
response to light stimulusGO:00094161240.053
purine containing compound metabolic processGO:00725211550.052
regulation of autophagyGO:0010506620.052
response to external biotic stimulusGO:00432072930.052
open tracheal system developmentGO:00074242040.051
developmental programmed cell deathGO:00106231380.051
cellular response to nutrient levelsGO:0031669620.050
positive regulation of cell motilityGO:200014730.050
skeletal muscle organ developmentGO:0060538480.049
response to starvationGO:0042594970.049
positive regulation of nucleic acid templated transcriptionGO:19035082660.049
regulation of molecular functionGO:00650092170.049
purine nucleotide catabolic processGO:00061951090.049
immune responseGO:00069552460.048
regulation of transcription from rna polymerase ii promoterGO:00063573780.048
ribonucleoside monophosphate catabolic processGO:0009158390.047
membrane organizationGO:00610241120.047
purine ribonucleotide catabolic processGO:00091541090.047
negative regulation of sequence specific dna binding transcription factor activityGO:004343340.047
positive regulation of rna metabolic processGO:00512542710.046
response to woundingGO:0009611940.046
mitotic nuclear divisionGO:00070672130.046
reactive oxygen species metabolic processGO:0072593220.046
regulation of cell growthGO:0001558430.045
translationGO:0006412690.045
post embryonic appendage morphogenesisGO:00351203850.045
cardiovascular system developmentGO:0072358820.045
response to other organismGO:00517072930.044
ribonucleoside catabolic processGO:00424541120.044
single organism cell adhesionGO:0098602470.044
organic substance transportGO:00717022570.044
negative regulation of gene expressionGO:00106293870.044
organic cyclic compound catabolic processGO:19013611680.044
cellular ketone metabolic processGO:0042180240.044
negative regulation of biosynthetic processGO:00098902770.044
positive regulation of biosynthetic processGO:00098913160.043
jak stat cascadeGO:0007259490.043
positive regulation of protein metabolic processGO:00512471280.043
cellular amine metabolic processGO:0044106120.043
actomyosin structure organizationGO:0031032560.042
tube morphogenesisGO:00352391910.042
developmental maturationGO:00217001720.041
cellular modified amino acid metabolic processGO:0006575450.041
cellular response to starvationGO:0009267610.040
dna conformation changeGO:00711031050.040
dendrite developmentGO:00163582040.039
regulation of anatomical structure sizeGO:00900661630.039
purine nucleoside monophosphate metabolic processGO:0009126500.039
developmental pigmentationGO:0048066680.039
regulation of catalytic activityGO:00507901850.039
lipid metabolic processGO:00066291210.039
biological adhesionGO:00226101380.038
kidney developmentGO:000182230.038
cellular response to insulin stimulusGO:0032869280.037
cellular homeostasisGO:0019725800.037
organophosphate biosynthetic processGO:0090407460.037
single organism intracellular transportGO:19025822070.037
sister chromatid segregationGO:0000819920.036
cellular nitrogen compound catabolic processGO:00442701650.036
centriole replicationGO:0007099240.036
microtubule based movementGO:0007018510.036
retinal cell programmed cell deathGO:0046666250.036
cellular macromolecular complex assemblyGO:00346221530.036
positive regulation of molecular functionGO:00440931360.036
regulation of protein modification processGO:00313991120.035
establishment or maintenance of cell polarityGO:00071631670.035
nucleobase containing compound catabolic processGO:00346551650.035
autophagic cell deathGO:0048102830.035
generation of precursor metabolites and energyGO:0006091420.035
tissue morphogenesisGO:00487292970.035
establishment of localization in cellGO:00516494020.035
negative regulation of cell deathGO:0060548810.035
purine ribonucleoside triphosphate metabolic processGO:00092051190.034
skeletal muscle fiber developmentGO:004874130.034
endocytosisGO:00068973100.034
regulation of protein phosphorylationGO:0001932640.034
positive regulation of intracellular signal transductionGO:19025331160.033
locomotory behaviorGO:00076261760.033
larval developmentGO:00021641040.032
carbohydrate metabolic processGO:0005975820.032
cellular response to oxidative stressGO:0034599280.032
signal transduction by phosphorylationGO:00230141070.031
morphogenesis of an epitheliumGO:00020092760.031
cell agingGO:000756920.031
wound healingGO:0042060750.030
atp metabolic processGO:0046034490.030
histone modificationGO:00165701060.030
myotube differentiationGO:0014902460.030
rna processingGO:00063961470.030
cell proliferationGO:00082832990.030
carbohydrate derivative catabolic processGO:19011361180.030
regulation of translationGO:0006417560.030
camera type eye developmentGO:004301040.029
stem cell developmentGO:0048864790.029
posttranscriptional regulation of gene expressionGO:00106081450.029
regulation of phosphorylationGO:00423251470.029
skin developmentGO:0043588650.029
meiotic chromosome segregationGO:0045132590.028
transcription from rna polymerase ii promoterGO:00063663680.028
regulation of response to oxidative stressGO:190288240.028
regulation of locomotionGO:0040012420.028
salivary gland histolysisGO:0035070880.028
embryonic morphogenesisGO:00485982060.028
regulation of phosphate metabolic processGO:00192202100.028
response to radiationGO:00093141550.028
purine containing compound catabolic processGO:00725231120.028
hydrogen peroxide metabolic processGO:004274360.028
myotube cell developmentGO:001490430.028
receptor mediated endocytosisGO:0006898210.027
taxisGO:00423303040.027
pigment biosynthetic processGO:0046148360.027
positive regulation of locomotionGO:004001780.027
multi organism behaviorGO:00517051750.027
negative regulation of protein metabolic processGO:0051248850.027
positive regulation of growthGO:0045927750.027
positive regulation of chemotaxisGO:005092120.026
macromolecular complex assemblyGO:00650032560.026
single organism carbohydrate metabolic processGO:0044723720.026
chromosome organizationGO:00512763600.026
negative regulation of cellular component organizationGO:00511291080.026
eye morphogenesisGO:00485922600.026
alpha amino acid biosynthetic processGO:190160740.026
body morphogenesisGO:001017120.026
regulation of cell migrationGO:0030334220.026
negative regulation of cell developmentGO:0010721620.026
protein acylationGO:0043543420.026
salivary gland developmentGO:00074311620.026
regulation of cell motilityGO:2000145230.025
telencephalon developmentGO:002153720.025
organophosphate metabolic processGO:00196371950.025
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.025
chaperone mediated protein foldingGO:006107720.025
protein complex biogenesisGO:00702712010.025
ribonucleoside monophosphate metabolic processGO:0009161510.025
regulation of cell divisionGO:0051302720.025
single organism membrane organizationGO:0044802930.025
positive regulation of developmental growthGO:0048639620.024
germ cell migrationGO:0008354430.024
purine nucleotide metabolic processGO:00061631460.024
cellular response to arsenic containing substanceGO:007124360.024
regulation of proteolysisGO:0030162870.024
response to abiotic stimulusGO:00096283410.024
positive regulation of multicellular organismal processGO:00512401430.023
mitotic sister chromatid segregationGO:0000070870.023
sleepGO:0030431490.023
mitotic spindle organizationGO:00070522200.023
cell migrationGO:00164772380.023
forebrain developmentGO:003090020.022
chemical homeostasisGO:0048878920.022
regulation of cellular component movementGO:0051270420.022
response to temperature stimulusGO:00092661060.022
single organismal cell cell adhesionGO:0016337450.022
regulation of sister chromatid segregationGO:0033045280.021
regulation of chromatin silencingGO:0031935360.021
response to water deprivationGO:000941440.021
cation transportGO:00068121100.021
purine ribonucleoside monophosphate metabolic processGO:0009167500.021
cell growthGO:00160491080.021
localization of cellGO:00516742570.021
photoreceptor cell differentiationGO:00465301700.021
cell maturationGO:00484691440.021
nucleoside catabolic processGO:00091641120.021
negative regulation of cellular protein metabolic processGO:0032269850.021
ribonucleoside triphosphate metabolic processGO:00091991190.021
imaginal disc derived wing morphogenesisGO:00074763370.021
positive regulation of transportGO:0051050920.020
regulation of phosphorus metabolic processGO:00511742100.020
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.020
protein transportGO:00150311550.020
phagocytosisGO:00069092150.020
cellular carbohydrate metabolic processGO:0044262220.020
cellular amino acid metabolic processGO:0006520610.020
multicellular organismal reproductive behaviorGO:00330571100.020
positive regulation of protein phosphorylationGO:0001934340.020
response to biotic stimulusGO:00096072940.019
positive regulation of apoptotic processGO:0043065470.019
insulin receptor signaling pathwayGO:0008286250.019
carbohydrate catabolic processGO:001605270.019
lipid storageGO:0019915380.019
oxidation reduction processGO:00551141230.019
single organism behaviorGO:00447083910.019
purine ribonucleoside catabolic processGO:00461301120.019
nucleoside triphosphate catabolic processGO:00091431080.019
salivary gland cell autophagic cell deathGO:0035071830.019
negative regulation of programmed cell deathGO:0043069720.019
stem cell differentiationGO:00488631170.019
myosin filament assemblyGO:003103450.018
epidermis developmentGO:0008544650.018
positive regulation of phosphate metabolic processGO:00459371390.018
oocyte developmentGO:00485991240.018
response to hydrogen peroxideGO:0042542110.018
purine nucleoside triphosphate metabolic processGO:00091441190.018
cell adhesionGO:00071551360.018
chromatin silencingGO:0006342760.018
positive regulation of catalytic activityGO:00430851180.018
striated muscle tissue developmentGO:0014706270.018
regulation of dna metabolic processGO:0051052340.018
ribonucleotide metabolic processGO:00092591450.018
negative regulation of cell differentiationGO:00455961430.018
positive regulation of protein modification processGO:0031401580.017
purine containing compound biosynthetic processGO:0072522300.017
epithelial cell proliferationGO:0050673150.017
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.017
divalent metal ion transportGO:0070838260.017
negative regulation of developmental processGO:00510932010.017
cell cell junction organizationGO:0045216550.017
positive regulation of phosphorus metabolic processGO:00105621390.017
negative regulation of translationGO:0017148280.017
regulation of multicellular organismal developmentGO:20000264140.017
nucleoside monophosphate metabolic processGO:0009123520.017
cuticle pigmentationGO:0048067220.017
regulation of immune responseGO:00507761180.017
muscle tissue developmentGO:0060537300.017
defense response to bacteriumGO:00427421780.016
negative regulation of signal transductionGO:00099682060.016
chromatin organizationGO:00063252070.016
ribonucleoside metabolic processGO:00091191270.016
regulation of peptidase activityGO:0052547390.016
carbohydrate derivative metabolic processGO:19011352170.016
cellular macromolecule localizationGO:00707272200.016
chemotaxisGO:00069352490.016
regulation of transportGO:00510491810.016
chromatin remodelingGO:0006338720.016
pyridine containing compound metabolic processGO:007252430.015
negative regulation of molecular functionGO:0044092510.015
negative regulation of phosphate metabolic processGO:0045936450.015
regulation of retinal cell programmed cell deathGO:0046668180.015
regulation of response to external stimulusGO:00321011150.015
organelle fissionGO:00482853400.015
tissue deathGO:00162711020.015
stress activated protein kinase signaling cascadeGO:0031098550.015
protein maturationGO:0051604710.015
axon developmentGO:00615642970.015
purine nucleoside monophosphate catabolic processGO:0009128380.015
eye pigment metabolic processGO:0042441330.015
mitochondrion organizationGO:0007005650.015
regulation of cellular response to oxidative stressGO:190040740.015
heterocycle catabolic processGO:00467001660.015
response to organic substanceGO:00100332840.015
protein phosphorylationGO:00064681690.014
nucleoside monophosphate catabolic processGO:0009125390.014
regulation of mapk cascadeGO:0043408920.014
purine nucleotide biosynthetic processGO:0006164290.014
morphogenesis of larval imaginal disc epitheliumGO:001633550.014
chemosensory behaviorGO:00076351060.014
digestive tract developmentGO:00485651490.014
amino acid activationGO:004303830.014
negative regulation of intracellular signal transductionGO:1902532570.014
establishment of mitotic spindle orientationGO:0000132130.014
instar larval developmentGO:0002168550.013
mating behaviorGO:00076171060.013
cytoplasmic translationGO:000218100.013
exocrine system developmentGO:00352721620.013
microtubule cytoskeleton organization involved in mitosisGO:1902850520.013
regulation of neuron differentiationGO:00456641030.013
small molecule catabolic processGO:0044282210.013
regulation of membrane potentialGO:0042391350.013
purine ribonucleoside metabolic processGO:00461281270.013
response to hexoseGO:000974630.013
female meiotic divisionGO:0007143700.013
negative regulation of multicellular organismal processGO:00512411420.013
nucleoside phosphate catabolic processGO:19012921100.013
pentose metabolic processGO:001932110.013
golgi organizationGO:0007030660.013
mitotic cell cycle phase transitionGO:00447721380.013
embryo development ending in birth or egg hatchingGO:00097921520.013
male mating behaviorGO:0060179700.013
regulation of hydrolase activityGO:0051336970.013
mesenchymal cell developmentGO:001403110.013
atp catabolic processGO:0006200380.013
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.013
cellular response to oxygen levelsGO:0071453300.013
cell junction organizationGO:0034330570.013
sensory perception of soundGO:0007605560.012
establishment of mitotic spindle localizationGO:0040001170.012
terminal branching open tracheal systemGO:0007430170.012
organonitrogen compound catabolic processGO:19015651280.012
digestive system developmentGO:00551231490.012
oocyte differentiationGO:00099941450.012
embryonic organ developmentGO:0048568500.012
regulation of nucleoside metabolic processGO:0009118500.012
response to endoplasmic reticulum stressGO:0034976280.012
microtubule based transportGO:0010970420.012
purine ribonucleoside monophosphate catabolic processGO:0009169380.012
lamellipodium assemblyGO:0030032210.012
cellular response to decreased oxygen levelsGO:0036294300.012
cardiac muscle cell differentiationGO:005500740.012
intracellular protein transportGO:00068861040.012
peptide metabolic processGO:0006518800.012
rna splicing via transesterification reactionsGO:0000375730.012
regulation of nuclear divisionGO:0051783580.012
single organism carbohydrate catabolic processGO:004472470.012
cellular amide metabolic processGO:0043603800.012
calcium ion transportGO:0006816240.012
neurological system processGO:00508773580.011
centriole assemblyGO:0098534240.011
defense response to other organismGO:00985422250.011
cellular lipid metabolic processGO:0044255830.011
maintenance of locationGO:0051235730.011
brain developmentGO:00074201200.011
response to inorganic substanceGO:0010035440.011
purine nucleoside biosynthetic processGO:004245130.011
ion transmembrane transportGO:00342201220.011
regulation of protein transportGO:0051223570.011
negative regulation of gene expression epigeneticGO:0045814770.011
positive regulation of immune system processGO:0002684680.011
regulation of cellular component biogenesisGO:00440872010.011
molting cycleGO:0042303560.011
cellularizationGO:0007349900.011
response to unfolded proteinGO:000698690.011
lipid localizationGO:0010876540.011
regulation of organelle organizationGO:00330431960.011
regulation of jak stat cascadeGO:0046425430.011
regulation of cell sizeGO:0008361630.011
positive regulation of notch signaling pathwayGO:0045747340.011
cellular macromolecule catabolic processGO:00442651360.011
cytoskeleton dependent intracellular transportGO:0030705440.011
small gtpase mediated signal transductionGO:0007264880.011
positive regulation of phosphorylationGO:0042327870.011
response to lipopolysaccharideGO:003249640.010
negative regulation of catalytic activityGO:0043086420.010
mitotic sister chromatid separationGO:0051306300.010
response to oxygen radicalGO:000030530.010
protein kinase b signalingGO:004349110.010
axon guidanceGO:00074112330.010
nucleoside triphosphate metabolic processGO:00091411200.010
purine nucleoside metabolic processGO:00422781270.010
intracellular protein transmembrane importGO:004474340.010
establishment of protein localization to membraneGO:0090150110.010

Trxr-1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
sensory system diseaseDOID:005015500.056
nervous system diseaseDOID:86300.056
disease of anatomical entityDOID:700.056
nonsyndromic deafnessDOID:005056300.056
auditory system diseaseDOID:274200.056
cardiovascular system diseaseDOID:128700.051
myopathyDOID:42300.051
muscular diseaseDOID:008000000.051
cardiomyopathyDOID:005070000.051
musculoskeletal system diseaseDOID:1700.051
intrinsic cardiomyopathyDOID:006003600.051
heart diseaseDOID:11400.051
muscle tissue diseaseDOID:6600.051
cancerDOID:16200.021
disease of cellular proliferationDOID:1456600.021
disease of metabolismDOID:001466700.019
inherited metabolic disorderDOID:65500.016
organ system cancerDOID:005068600.011