Drosophila melanogaster

193 known processes

Vps25 (Dmel_CG14750)

Vacuolar protein sorting 25

(Aliases: CG14750,Dmel\CG14750,l(2)44Db,VPS25,dVps25,l(2)k08904,vps25,ESCRT-I,ESCRT-II)

Vps25 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
germarium derived female germ line cyst formationGO:0030727420.996
ubiquitin dependent protein catabolic process via the multivesicular body sorting pathwayGO:004316280.995
germarium derived egg chamber formationGO:00072931010.993
endosome transport via multivesicular body sorting pathwayGO:0032509120.991
female germ line cyst formationGO:0048135420.989
germ line cyst formationGO:0048134440.954
ovarian follicle cell developmentGO:00307072480.947
ovarian follicle cell stalk formationGO:0030713170.941
regulation of notch signaling pathwayGO:00085931000.861
single organism membrane fusionGO:0044801420.798
regulation of epidermal growth factor receptor signaling pathwayGO:0042058420.778
regulation of erbb signaling pathwayGO:1901184420.769
membrane organizationGO:00610241120.674
endosomal transportGO:0016197440.621
cell proliferationGO:00082832990.543
columnar cuboidal epithelial cell developmentGO:00020662490.526
positive regulation of cellular component organizationGO:00511301560.510
erbb signaling pathwayGO:0038127580.447
morphogenesis of follicular epitheliumGO:0016333360.439
epithelial cell differentiationGO:00308553220.433
protein modification by small protein conjugation or removalGO:00706471060.423
proteolysis involved in cellular protein catabolic processGO:0051603830.415
regionalizationGO:00030024160.389
ubiquitin dependent protein catabolic processGO:0006511780.384
protein catabolic processGO:00301631010.377
single organism cellular localizationGO:19025801800.369
Yeast
negative regulation of erbb signaling pathwayGO:1901185290.331
regulation of immune responseGO:00507761180.317
regulation of apoptotic processGO:00429811300.316
protein ubiquitinationGO:0016567700.307
cell deathGO:00082192790.301
modification dependent protein catabolic processGO:0019941780.291
blastoderm segmentationGO:00073501590.278
notch signaling pathwayGO:00072191200.278
immune system processGO:00023763470.255
enzyme linked receptor protein signaling pathwayGO:00071671790.253
negative regulation of signal transductionGO:00099682060.230
vesicle mediated transportGO:00161923810.229
establishment or maintenance of polarity of follicular epitheliumGO:0016334260.226
oocyte developmentGO:00485991240.225
membrane buddingGO:000690040.223
regulation of response to stressGO:00801342000.215
axis specificationGO:00097981670.188
negative regulation of response to stimulusGO:00485852580.187
regulation of cell cycle phase transitionGO:19019871300.184
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.184
single organism membrane organizationGO:0044802930.181
regulation of cell proliferationGO:00421271630.177
compound eye developmentGO:00487493070.177
autophagyGO:00069141080.176
purine ribonucleoside metabolic processGO:00461281270.160
deathGO:00162652840.158
vacuolar transportGO:0007034130.154
Yeast
response to extracellular stimulusGO:00099911160.154
cytoplasmic transportGO:00164821300.139
Yeast
glycosyl compound metabolic processGO:19016571270.139
nucleoside metabolic processGO:00091161270.139
organelle membrane fusionGO:0090174160.138
negative regulation of gene expressionGO:00106293870.135
Yeast
regulation of transcription from rna polymerase ii promoterGO:00063573780.135
Yeast
developmental maturationGO:00217001720.133
reproductive structure developmentGO:0048608740.130
epidermal growth factor receptor signaling pathwayGO:0007173580.127
cellular macromolecule localizationGO:00707272200.126
Yeast
cellular macromolecule catabolic processGO:00442651360.126
regulation of cellular catabolic processGO:00313291570.121
anterior posterior pattern specificationGO:00099521360.120
regulation of cell cycleGO:00517262910.118
positive regulation of macromolecule metabolic processGO:00106044050.114
vesicle organizationGO:0016050440.114
morphogenesis of an epitheliumGO:00020092760.113
organelle fusionGO:0048284460.113
positive regulation of response to stimulusGO:00485843230.112
cellular protein catabolic processGO:0044257830.111
segmentationGO:00352822070.110
modification dependent macromolecule catabolic processGO:0043632790.109
regulation of innate immune responseGO:0045088710.108
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.108
agingGO:00075681430.107
multicellular organismal agingGO:00102591400.106
columnar cuboidal epithelial cell differentiationGO:00020652560.106
intracellular transportGO:00469072280.103
regulation of cell deathGO:00109411730.102
organelle assemblyGO:00709251980.101
organic substance catabolic processGO:19015753080.098
oocyte constructionGO:00073081120.098
single organism membrane buddingGO:190259120.097
protein modification by small protein conjugationGO:0032446790.094
regulation of programmed cell deathGO:00430671520.091
negative regulation of cell communicationGO:00106482230.090
protein modification processGO:00362114380.089
epithelial cell developmentGO:00020642740.089
programmed cell deathGO:00125012570.086
small molecule metabolic processGO:00442813050.083
cell cycle phase transitionGO:00447701400.083
endocytosisGO:00068973100.082
endomembrane system organizationGO:00102561190.082
establishment or maintenance of cell polarityGO:00071631670.081
protein localizationGO:00081042840.080
negative regulation of epithelial cell proliferationGO:005068040.080
negative regulation of signalingGO:00230572190.078
determination of adult lifespanGO:00083401370.077
regulation of multi organism processGO:00439001310.076
reproductive system developmentGO:0061458740.074
molting cycleGO:0042303560.074
sex differentiationGO:0007548810.074
embryo development ending in birth or egg hatchingGO:00097921520.069
ribonucleoside triphosphate metabolic processGO:00091991190.065
macromolecule catabolic processGO:00090571610.062
cell motilityGO:00488702510.062
apoptotic processGO:00069151590.061
endosomal vesicle fusionGO:003405840.060
protein complex biogenesisGO:00702712010.059
cellular protein localizationGO:00346131600.058
Yeast
negative regulation of nitrogen compound metabolic processGO:00511722650.058
Yeast
photoreceptor cell differentiationGO:00465301700.058
purine nucleoside metabolic processGO:00422781270.057
establishment of oocyte nucleus localization involved in oocyte dorsal ventral axis specificationGO:003072260.055
body morphogenesisGO:001017120.055
establishment of localization in cellGO:00516494020.054
protein complex assemblyGO:00064612000.053
positive regulation of cellular biosynthetic processGO:00313283160.052
catabolic processGO:00090564090.050
transcription from rna polymerase ii promoterGO:00063663680.050
Yeast
regulation of organelle organizationGO:00330431960.050
regulation of epithelial cell proliferationGO:005067840.050
response to nutrient levelsGO:00316671140.049
carbohydrate derivative metabolic processGO:19011352170.048
positive regulation of cellular protein metabolic processGO:00322701180.048
establishment or maintenance of microtubule cytoskeleton polarityGO:0030951410.047
regulation of phosphate metabolic processGO:00192202100.046
macromolecular complex assemblyGO:00650032560.045
positive regulation of macromolecule biosynthetic processGO:00105572830.045
proteolysisGO:00065081920.045
regulation of mitotic cell cycleGO:00073461900.044
nucleoside phosphate metabolic processGO:00067531620.044
anterior posterior axis specificationGO:00099481090.044
purine nucleoside triphosphate metabolic processGO:00091441190.044
cellularizationGO:0007349900.044
protein transportGO:00150311550.043
cell adhesionGO:00071551360.043
cellular catabolic processGO:00442483720.043
negative regulation of biosynthetic processGO:00098902770.042
Yeast
cell divisionGO:00513012480.042
carbohydrate derivative biosynthetic processGO:1901137850.040
phosphorylationGO:00163102940.040
regulation of molecular functionGO:00650092170.039
regulation of cellular protein metabolic processGO:00322682430.039
positive regulation of biosynthetic processGO:00098913160.039
single organism intracellular transportGO:19025822070.038
axon developmentGO:00615642970.038
mrna processingGO:00063971040.038
regulation of cell shapeGO:00083601130.037
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.037
Yeast
negative regulation of cell proliferationGO:0008285690.035
regulation of anatomical structure morphogenesisGO:00226032420.035
regulation of cell cycle processGO:00105641810.035
oocyte differentiationGO:00099941450.034
purine ribonucleotide metabolic processGO:00091501450.034
response to starvationGO:0042594970.034
cellular protein modification processGO:00064644380.034
pole plasm oskar mrna localizationGO:0045451460.034
cellular protein complex assemblyGO:0043623710.034
development of primary sexual characteristicsGO:0045137500.034
negative regulation of macromolecule biosynthetic processGO:00105582700.034
Yeast
negative regulation of apoptotic processGO:0043066630.033
germarium derived oocyte differentiationGO:0030706290.033
protein secretionGO:0009306450.033
axonogenesisGO:00074092900.033
negative regulation of cellular metabolic processGO:00313243820.032
Yeast
purine containing compound metabolic processGO:00725211550.032
regulation of protein metabolic processGO:00512462560.032
defense responseGO:00069523000.031
positive regulation of cell communicationGO:00106472500.031
autophagic vacuole fusionGO:0000046150.031
cellular ketone metabolic processGO:0042180240.031
regulation of localizationGO:00328792750.031
purine ribonucleoside triphosphate metabolic processGO:00092051190.031
positive regulation of rna biosynthetic processGO:19026802660.031
immune responseGO:00069552460.031
eye developmentGO:00016543230.030
ribose phosphate metabolic processGO:00196931450.030
embryonic pattern specificationGO:00098801740.030
cuticle developmentGO:0042335860.029
regulation of immune system processGO:00026821760.029
positive regulation of signal transductionGO:00099672230.029
negative regulation of mitotic cell cycleGO:00459301090.029
regulation of phosphorus metabolic processGO:00511742100.029
negative regulation of notch signaling pathwayGO:0045746410.029
single organism catabolic processGO:00447122280.028
oocyte axis specificationGO:00073091080.028
oocyte anterior posterior axis specificationGO:0007314720.028
homeostatic processGO:00425921990.027
compound eye morphogenesisGO:00017452490.027
regulation of microtubule based processGO:0032886490.027
regulation of cellular localizationGO:00603411360.027
germarium derived oocyte fate determinationGO:0007294260.026
response to bacteriumGO:00096171980.026
positive regulation of immune responseGO:0050778630.026
defense response to gram negative bacteriumGO:0050829940.026
camera type eye developmentGO:004301040.025
organonitrogen compound metabolic processGO:19015643180.025
smoothened signaling pathwayGO:0007224490.025
positive regulation of signalingGO:00230562430.025
cell projection assemblyGO:0030031940.025
regulation of dna templated transcription elongationGO:0032784170.025
early endosome to late endosome transportGO:004502230.025
regulation of mitotic cell cycle phase transitionGO:19019901300.024
notch receptor processingGO:0007220130.024
male gamete generationGO:00482322010.024
regulation of intracellular signal transductionGO:19025312360.024
intracellular mrna localization involved in pattern specification processGO:0060810560.024
defense response to bacteriumGO:00427421780.024
positive regulation of apoptotic processGO:0043065470.024
positive regulation of cell deathGO:0010942690.024
mitotic cell cycle phase transitionGO:00447721380.023
purine containing compound catabolic processGO:00725231120.023
protein localization to organelleGO:0033365820.023
Yeast
regulation of symbiosis encompassing mutualism through parasitismGO:0043903150.023
regulation of protein modification processGO:00313991120.023
mrna splicing via spliceosomeGO:0000398730.023
regulation of cell differentiationGO:00455953020.022
eye morphogenesisGO:00485922600.022
positive regulation of transcription dna templatedGO:00458932660.022
regulation of protein ubiquitinationGO:0031396220.022
regulation of cellular component sizeGO:0032535980.022
organophosphate metabolic processGO:00196371950.022
oocyte microtubule cytoskeleton organizationGO:0016325350.021
imaginal disc pattern formationGO:0007447910.021
cell maturationGO:00484691440.021
regulation of autophagyGO:0010506620.021
innate immune responseGO:00450871440.021
regulation of catalytic activityGO:00507901850.021
dna templated transcription elongationGO:0006354180.021
ribonucleotide metabolic processGO:00092591450.021
anatomical structure homeostasisGO:0060249970.020
cation transportGO:00068121100.020
regulation of protein modification by small protein conjugation or removalGO:1903320250.020
proteasomal protein catabolic processGO:0010498590.020
retina development in camera type eyeGO:006004140.020
regulation of catabolic processGO:00098941700.020
asymmetric protein localizationGO:0008105330.020
cellular response to extracellular stimulusGO:0031668640.020
cellular macromolecular complex assemblyGO:00346221530.020
protein localization to membraneGO:0072657190.020
instar larval developmentGO:0002168550.019
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.019
negative regulation of programmed cell deathGO:0043069720.019
positive regulation of organelle organizationGO:0010638650.019
oocyte microtubule cytoskeleton polarizationGO:0008103220.019
larval developmentGO:00021641040.018
growthGO:00400073590.018
embryonic hemopoiesisGO:0035162260.018
membrane fusionGO:0061025420.018
positive regulation of programmed cell deathGO:0043068620.018
cellular response to starvationGO:0009267610.017
dendrite morphogenesisGO:00488131990.017
lipid metabolic processGO:00066291210.017
cellular response to dna damage stimulusGO:00069742230.017
atp metabolic processGO:0046034490.017
regulation of nervous system developmentGO:00519602480.017
embryonic morphogenesisGO:00485982060.017
establishment of protein localization to organelleGO:0072594620.017
Yeast
cellular response to nutrient levelsGO:0031669620.017
negative regulation of cell deathGO:0060548810.017
compound eye photoreceptor cell differentiationGO:00017511400.017
posttranscriptional regulation of gene expressionGO:00106081450.017
positive regulation of molecular functionGO:00440931360.017
regulation of cell morphogenesisGO:00226041630.016
negative regulation of molecular functionGO:0044092510.016
chemotaxisGO:00069352490.016
ribonucleoside metabolic processGO:00091191270.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
ion transportGO:00068111450.015
ovarian follicle cell migrationGO:00072971210.015
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.015
cellular response to external stimulusGO:0071496660.015
response to organic substanceGO:00100332840.015
gonad developmentGO:0008406500.015
positive regulation of rna metabolic processGO:00512542710.015
autophagic vacuole assemblyGO:000004520.014
tripartite regional subdivisionGO:00073511030.014
positive regulation of gene expressionGO:00106282900.014
positive regulation of protein metabolic processGO:00512471280.014
positive regulation of protein modification processGO:0031401580.014
pole plasm rna localizationGO:0007316520.014
negative regulation of growthGO:0045926840.014
cell growthGO:00160491080.013
mitotic nuclear divisionGO:00070672130.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
response to organic cyclic compoundGO:0014070890.013
regulation of cellular amine metabolic processGO:003323830.013
positive regulation of phosphate metabolic processGO:00459371390.013
maintenance of cell polarityGO:0030011180.013
regulation of proteolysisGO:0030162870.013
regulation of neuron differentiationGO:00456641030.013
interspecies interaction between organismsGO:0044419160.013
positive regulation of phosphorus metabolic processGO:00105621390.013
eye photoreceptor cell differentiationGO:00017541450.013
phagocytosisGO:00069092150.012
regulation of cellular component biogenesisGO:00440872010.012
guanosine containing compound catabolic processGO:1901069740.012
production of small rna involved in gene silencing by rnaGO:0070918150.012
appendage developmentGO:00487364010.012
ncrna metabolic processGO:0034660430.012
purine nucleotide metabolic processGO:00061631460.012
regulation of anatomical structure sizeGO:00900661630.012
wing disc morphogenesisGO:00074723440.012
negative regulation of multicellular organismal processGO:00512411420.012
membrane protein proteolysisGO:003361960.012
intracellular protein transportGO:00068861040.012
Yeast
organelle fissionGO:00482853400.012
scf dependent proteasomal ubiquitin dependent protein catabolic processGO:003114610.012
nucleoside monophosphate metabolic processGO:0009123520.012
nucleoside phosphate catabolic processGO:19012921100.012
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.012
rna processingGO:00063961470.011
symbiosis encompassing mutualism through parasitismGO:0044403160.011
defense response to other organismGO:00985422250.011
histone modificationGO:00165701060.011
oocyte fate determinationGO:0030716270.011
imaginal disc derived appendage developmentGO:00487373990.011
mapk cascadeGO:00001651070.011
regulation of phosphorylationGO:00423251470.011
tissue morphogenesisGO:00487292970.011
positive regulation of nucleic acid templated transcriptionGO:19035082660.011
nucleobase containing small molecule metabolic processGO:00550861740.011
mitotic cytokinesisGO:0000281500.011
cell migrationGO:00164772380.011
regulation of cell developmentGO:00602842150.011
establishment of protein localizationGO:00451841630.011
peptidyl lysine modificationGO:0018205570.011
maintenance of locationGO:0051235730.011
organophosphate catabolic processGO:00464341120.011
nucleoside triphosphate metabolic processGO:00091411200.011
endosome organizationGO:000703290.011
signal transduction by phosphorylationGO:00230141070.011
dsrna fragmentationGO:0031050150.010
establishment or maintenance of bipolar cell polarityGO:0061245340.010
post embryonic appendage morphogenesisGO:00351203850.010
purine ribonucleoside triphosphate catabolic processGO:00092071080.010
organonitrogen compound biosynthetic processGO:19015661170.010

Vps25 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.047
nervous system diseaseDOID:86300.014
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012