Drosophila melanogaster

66 known processes

Tie (Dmel_CG7525)

Tie-like receptor tyrosine kinase

(Aliases: tie,DPR1,Dmel\CG7525,RTK,CG7525)

Tie biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
deathGO:00162652840.118
regulation of cell developmentGO:00602842150.088
cell proliferationGO:00082832990.086
detection of chemical stimulusGO:0009593930.082
cellular protein modification processGO:00064644380.079
response to abiotic stimulusGO:00096283410.075
response to extracellular stimulusGO:00099911160.073
detection of stimulusGO:00516061560.070
chromosome organizationGO:00512763600.069
protein modification processGO:00362114380.069
regulation of cell deathGO:00109411730.068
homeostatic processGO:00425921990.067
cell deathGO:00082192790.065
positive regulation of lipid storageGO:001088440.064
negative regulation of developmental processGO:00510932010.056
programmed cell deathGO:00125012570.052
axonogenesisGO:00074092900.052
regulation of nervous system developmentGO:00519602480.051
positive regulation of macromolecule metabolic processGO:00106044050.050
tissue deathGO:00162711020.050
cellular response to radiationGO:0071478520.049
appendage morphogenesisGO:00351073970.048
cellular response to abiotic stimulusGO:0071214580.047
response to radiationGO:00093141550.047
imaginal disc derived wing morphogenesisGO:00074763370.046
regulation of transcription from rna polymerase ii promoterGO:00063573780.046
phosphorylationGO:00163102940.044
post embryonic appendage morphogenesisGO:00351203850.044
negative regulation of cellular biosynthetic processGO:00313272770.044
organic cyclic compound catabolic processGO:19013611680.044
appendage developmentGO:00487364010.043
organic substance catabolic processGO:19015753080.042
regulation of multicellular organismal developmentGO:20000264140.042
single organism biosynthetic processGO:00447112060.042
lipopolysaccharide mediated signaling pathwayGO:003166310.040
taxisGO:00423303040.039
regulation of cell differentiationGO:00455953020.038
multicellular organismal agingGO:00102591400.037
salivary gland morphogenesisGO:00074351450.036
regulation of neuron differentiationGO:00456641030.036
transcription from rna polymerase ii promoterGO:00063663680.036
positive regulation of gene expressionGO:00106282900.035
negative regulation of macromolecule biosynthetic processGO:00105582700.035
negative regulation of cellular metabolic processGO:00313243820.035
exocrine system developmentGO:00352721620.034
pigment metabolic process involved in pigmentationGO:0043474330.033
regulation of molecular functionGO:00650092170.033
cell motilityGO:00488702510.033
small molecule metabolic processGO:00442813050.032
axon developmentGO:00615642970.032
intracellular signal transductionGO:00355563000.032
negative regulation of gene expressionGO:00106293870.032
nucleobase containing compound catabolic processGO:00346551650.032
response to lipopolysaccharideGO:003249640.032
acetylcholine metabolic processGO:000829120.031
body morphogenesisGO:001017120.031
regulation of neurogenesisGO:00507671580.031
negative regulation of nervous system developmentGO:0051961920.031
regulation of intracellular signal transductionGO:19025312360.030
regulation of cellular protein metabolic processGO:00322682430.030
positive regulation of nucleobase containing compound metabolic processGO:00459353320.030
cellular response to dna damage stimulusGO:00069742230.030
regulation of mitotic cell cycleGO:00073461900.029
developmental pigmentationGO:0048066680.029
organic substance transportGO:00717022570.029
response to biotic stimulusGO:00096072940.029
agingGO:00075681430.029
developmental programmed cell deathGO:00106231380.029
catabolic processGO:00090564090.029
response to light stimulusGO:00094161240.028
developmental growthGO:00485892800.028
cellular catabolic processGO:00442483720.028
organelle assemblyGO:00709251980.028
pigmentationGO:0043473750.028
response to organophosphorusGO:004668320.027
response to nutrient levelsGO:00316671140.027
positive regulation of molecular functionGO:00440931360.027
response to other organismGO:00517072930.027
cellular nitrogen compound catabolic processGO:00442701650.027
cellular macromolecule localizationGO:00707272200.027
aromatic compound catabolic processGO:00194391660.027
macromolecular complex assemblyGO:00650032560.026
protein phosphorylationGO:00064681690.026
organelle fissionGO:00482853400.026
nuclear divisionGO:00002803320.026
chromosome segregationGO:00070591570.026
eye pigment biosynthetic processGO:0006726320.025
positive regulation of catalytic activityGO:00430851180.025
negative regulation of rna biosynthetic processGO:19026792400.025
positive regulation of phosphate metabolic processGO:00459371390.025
macromolecule catabolic processGO:00090571610.025
cholesterol transportGO:003030120.025
response to bacteriumGO:00096171980.025
regulation of transportGO:00510491810.025
protein complex assemblyGO:00064612000.025
imaginal disc derived appendage morphogenesisGO:00351143950.024
regulation of phosphorus metabolic processGO:00511742100.024
central nervous system developmentGO:00074172010.024
vitamin metabolic processGO:000676620.024
cellular response to chemical stimulusGO:00708871990.024
regulation of catalytic activityGO:00507901850.024
neuron projection guidanceGO:00974852410.024
rhodopsin metabolic processGO:0046154100.024
negative regulation of nitrogen compound metabolic processGO:00511722650.024
defense response to other organismGO:00985422250.024
cellular response to uvGO:0034644120.024
carbohydrate derivative metabolic processGO:19011352170.023
negative regulation of rna metabolic processGO:00512532510.023
regulation of cellular component biogenesisGO:00440872010.023
regulation of response to stressGO:00801342000.023
immune system processGO:00023763470.023
vesicle mediated transportGO:00161923810.023
organonitrogen compound metabolic processGO:19015643180.023
regionalizationGO:00030024160.023
regulation of localizationGO:00328792750.023
negative regulation of cell developmentGO:0010721620.023
gliogenesisGO:0042063800.023
lipid metabolic processGO:00066291210.023
regulation of programmed cell deathGO:00430671520.022
protein complex biogenesisGO:00702712010.022
pigment metabolic processGO:0042440840.022
axon guidanceGO:00074112330.022
cellular amine metabolic processGO:0044106120.021
gland morphogenesisGO:00226121450.021
single organism intracellular transportGO:19025822070.021
negative regulation of transcription dna templatedGO:00458922370.021
positive regulation of nervous system developmentGO:0051962690.021
regulation of lipid storageGO:0010883220.021
epithelial cell migrationGO:00106311480.021
chromatin organizationGO:00063252070.021
wing disc morphogenesisGO:00074723440.021
response to external biotic stimulusGO:00432072930.021
negative regulation of response to stimulusGO:00485852580.021
phototransductionGO:0007602520.021
salivary gland cell autophagic cell deathGO:0035071830.021
nucleoside phosphate catabolic processGO:19012921100.020
salivary gland developmentGO:00074311620.020
regulation of phosphorylationGO:00423251470.020
dna metabolic processGO:00062592270.020
ethanolamine containing compound metabolic processGO:004243940.020
detection of abiotic stimulusGO:0009582660.020
columnar cuboidal epithelial cell differentiationGO:00020652560.020
heterocycle catabolic processGO:00467001660.020
imaginal disc derived appendage developmentGO:00487373990.020
cuticle developmentGO:0042335860.019
negative regulation of nucleobase containing compound metabolic processGO:00459342610.019
phagocytosisGO:00069092150.019
epithelial cell differentiationGO:00308553220.019
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.019
immune response regulating signaling pathwayGO:000276420.019
salivary gland histolysisGO:0035070880.019
ovarian follicle cell developmentGO:00307072480.019
regulation of cell cycleGO:00517262910.019
morphogenesis of an epitheliumGO:00020092760.019
apoptotic processGO:00069151590.019
purine ribonucleotide metabolic processGO:00091501450.019
skin developmentGO:0043588650.019
regulation of cellular catabolic processGO:00313291570.019
positive regulation of cell developmentGO:0010720610.019
positive regulation of phosphorus metabolic processGO:00105621390.019
negative regulation of multicellular organismal processGO:00512411420.019
regulation of anatomical structure sizeGO:00900661630.018
negative regulation of biosynthetic processGO:00098902770.018
amine metabolic processGO:0009308120.018
regulation of cellular response to stressGO:0080135890.018
cellular response to lipopolysaccharideGO:007122230.018
regulation of phosphate metabolic processGO:00192202100.018
positive regulation of cell communicationGO:00106472500.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
cell cycle phase transitionGO:00447701400.018
negative regulation of cell communicationGO:00106482230.018
positive regulation of cell migrationGO:003033520.018
regulation of apoptotic processGO:00429811300.017
cellular response to organic substanceGO:00713101320.017
positive regulation of multicellular organismal processGO:00512401430.017
regulation of epithelial cell differentiationGO:003085640.017
regulation of protein metabolic processGO:00512462560.017
cell cell signaling involved in cell fate commitmentGO:00451682100.017
ras protein signal transductionGO:0007265880.017
cellular macromolecule catabolic processGO:00442651360.017
cellular amino acid metabolic processGO:0006520610.017
ovarian follicle cell migrationGO:00072971210.017
negative regulation of cell cycle phase transitionGO:19019881030.017
negative regulation of signal transductionGO:00099682060.017
neurological system processGO:00508773580.017
meiotic cell cycleGO:00513211710.017
cellular response to molecule of bacterial originGO:007121930.017
lateral inhibitionGO:00463312060.017
lipid biosynthetic processGO:0008610460.016
single organism cellular localizationGO:19025801800.016
histolysisGO:00075591020.016
regulation of immune system processGO:00026821760.016
positive regulation of nitrogen compound metabolic processGO:00511733540.016
lipid localizationGO:0010876540.016
positive regulation of protein metabolic processGO:00512471280.016
response to temperature stimulusGO:00092661060.016
cellular homeostasisGO:0019725800.016
ameboidal type cell migrationGO:00016671510.016
positive regulation of macromolecule biosynthetic processGO:00105572830.016
kidney developmentGO:000182230.016
positive regulation of cellular component organizationGO:00511301560.016
actin filament based processGO:00300292200.016
positive regulation of cell proliferationGO:0008284470.016
eye pigment metabolic processGO:0042441330.016
single organism catabolic processGO:00447122280.016
endocytosisGO:00068973100.016
regulation of cell proliferationGO:00421271630.016
cellular response to biotic stimulusGO:007121640.016
actin cytoskeleton organizationGO:00300362060.015
negative regulation of cellular component organizationGO:00511291080.015
regulation of rna splicingGO:0043484690.015
negative regulation of programmed cell deathGO:0043069720.015
response to ionizing radiationGO:0010212320.015
anion homeostasisGO:005508130.015
segmentationGO:00352822070.015
positive regulation of cell differentiationGO:0045597640.015
organonitrogen compound catabolic processGO:19015651280.015
spindle assemblyGO:0051225800.015
autophagic cell deathGO:0048102830.015
protein localizationGO:00081042840.015
chemotaxisGO:00069352490.015
positive regulation of biosynthetic processGO:00098913160.015
cellular lipid metabolic processGO:0044255830.015
response to uvGO:0009411240.015
cellular component assembly involved in morphogenesisGO:00109271510.015
peptidyl amino acid modificationGO:00181931050.015
androgen metabolic processGO:000820910.015
regulation of organelle organizationGO:00330431960.014
response to oxygen containing compoundGO:19017002000.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
pigment biosynthetic processGO:0046148360.014
regulation of cellular ketone metabolic processGO:001056530.014
cell adhesionGO:00071551360.014
jak stat cascadeGO:0007259490.014
positive regulation of neurogenesisGO:0050769410.014
connective tissue developmentGO:006144830.014
protein catabolic processGO:00301631010.014
cell recognitionGO:00080371020.014
ribonucleotide catabolic processGO:00092611090.014
epidermal cell differentiationGO:0009913510.014
positive regulation of cellular component biogenesisGO:0044089800.014
regulation of catabolic processGO:00098941700.014
tetraterpenoid metabolic processGO:001610810.014
intracellular transportGO:00469072280.014
axis specificationGO:00097981670.014
ribonucleoside triphosphate catabolic processGO:00092031080.014
tissue migrationGO:00901301550.014
negative regulation of homeostatic processGO:003284520.014
regulation of microtubule polymerization or depolymerizationGO:0031110270.014
defense response to gram negative bacteriumGO:0050829940.014
sterol homeostasisGO:005509240.014
compound eye developmentGO:00487493070.014
small gtpase mediated signal transductionGO:0007264880.014
response to organic substanceGO:00100332840.014
purine nucleotide metabolic processGO:00061631460.014
g protein coupled receptor signaling pathwayGO:00071861360.014
positive regulation of cellular protein metabolic processGO:00322701180.014
determination of adult lifespanGO:00083401370.014
cellular response to oxygen containing compoundGO:1901701790.013
positive regulation of phosphorylationGO:0042327870.013
negative regulation of nucleic acid templated transcriptionGO:19035072400.013
purine nucleoside catabolic processGO:00061521120.013
chitin based cuticle developmentGO:0040003490.013
tissue morphogenesisGO:00487292970.013
carboxylic acid metabolic processGO:0019752920.013
nucleoside phosphate metabolic processGO:00067531620.013
regulation of protein modification processGO:00313991120.013
immune responseGO:00069552460.013
anatomical structure homeostasisGO:0060249970.013
negative regulation of mitotic cell cycleGO:00459301090.013
nucleoside triphosphate catabolic processGO:00091431080.013
cellular response to light stimulusGO:0071482370.013
negative regulation of apoptotic processGO:0043066630.013
cell divisionGO:00513012480.013
hair cell differentiationGO:0035315470.013
regulation of cell projection organizationGO:0031344920.013
gene silencingGO:00164581380.013
photoreceptor cell developmentGO:0042461960.013
negative regulation of mitotic cell cycle phase transitionGO:19019911030.013
ribonucleoside metabolic processGO:00091191270.013
chromatin modificationGO:00165681470.013
xenobiotic catabolic processGO:004217810.013
growthGO:00400073590.013
imaginal disc pattern formationGO:0007447910.013
organic acid metabolic processGO:00060821030.013
regulation of anatomical structure morphogenesisGO:00226032420.013
response to endogenous stimulusGO:00097191190.013
cellular ketone metabolic processGO:0042180240.013
localization of cellGO:00516742570.013
chemical homeostasisGO:0048878920.013
positive regulation of nucleic acid templated transcriptionGO:19035082660.012
organophosphate catabolic processGO:00464341120.012
endomembrane system organizationGO:00102561190.012
purine containing compound catabolic processGO:00725231120.012
positive regulation of signal transductionGO:00099672230.012
regulation of cellular amino acid metabolic processGO:000652100.012
developmental maturationGO:00217001720.012
ribose phosphate metabolic processGO:00196931450.012
adult behaviorGO:00305341370.012
mitotic nuclear divisionGO:00070672130.012
cell junction organizationGO:0034330570.012
ribonucleoside monophosphate catabolic processGO:0009158390.012
negative regulation of signalingGO:00230572190.012
nucleobase containing small molecule metabolic processGO:00550861740.012
regulation of cellular component sizeGO:0032535980.012
histone modificationGO:00165701060.012
organophosphate metabolic processGO:00196371950.012
regulation of cell substrate adhesionGO:001081020.012
photoreceptor cell differentiationGO:00465301700.012
positive regulation of neuron differentiationGO:0045666260.012
negative regulation of cell cycleGO:00457861160.012
positive regulation of response to stimulusGO:00485843230.012
establishment of protein localizationGO:00451841630.012
muscle adaptationGO:004350010.012
positive regulation of signalingGO:00230562430.012
purine containing compound metabolic processGO:00725211550.012
steroid catabolic processGO:000670610.012
microtubule organizing center organizationGO:00310231680.012
open tracheal system developmentGO:00074242040.012
positive regulation of rna biosynthetic processGO:19026802660.012
nucleoside catabolic processGO:00091641120.011
forebrain developmentGO:003090020.011
negative regulation of cell cycle processGO:00109481090.011
eye pigmentationGO:0048069430.011
regulation of cellular amine metabolic processGO:003323830.011
lipid storageGO:0019915380.011
oxoacid metabolic processGO:00434361030.011
regulation of cell cycle phase transitionGO:19019871300.011
humoral immune responseGO:00069591170.011
negative regulation of intracellular signal transductionGO:1902532570.011
fat soluble vitamin metabolic processGO:000677510.011
respiratory system developmentGO:00605412130.011
defense response to bacteriumGO:00427421780.011
ribonucleoside catabolic processGO:00424541120.011
vitamin biosynthetic processGO:000911010.011
peptidyl tyrosine modificationGO:0018212240.011
hormone catabolic processGO:004244730.011
response to organic cyclic compoundGO:0014070890.011
organic hydroxy compound metabolic processGO:1901615830.011
spindle organizationGO:00070512530.011
membrane organizationGO:00610241120.011
positive regulation of cell motilityGO:200014730.011
rna processingGO:00063961470.011
regulation of endocytosisGO:0030100370.011
regulation of vesicle mediated transportGO:0060627590.011
chromosome separationGO:0051304420.011
columnar cuboidal epithelial cell developmentGO:00020662490.011
regulation of embryonic developmentGO:0045995680.011
response to oxidative stressGO:0006979860.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
epidermis developmentGO:0008544650.011
negative regulation of cell deathGO:0060548810.011
positive regulation of intracellular signal transductionGO:19025331160.011
response to glucoseGO:000974920.011
establishment of organelle localizationGO:00516561220.011
glycosyl compound catabolic processGO:19016581120.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
cell projection assemblyGO:0030031940.011
ion transportGO:00068111450.010
substrate adhesion dependent cell spreadingGO:003444620.010
negative regulation of cell differentiationGO:00455961430.010
blastoderm segmentationGO:00073501590.010
dorsal ventral pattern formationGO:00099531330.010
tripartite regional subdivisionGO:00073511030.010
negative regulation of cellular protein metabolic processGO:0032269850.010
regulation of purine nucleotide metabolic processGO:1900542620.010
embryonic pattern specificationGO:00098801740.010
defense responseGO:00069523000.010
positive regulation of hydrolase activityGO:0051345780.010
hindbrain developmentGO:003090220.010
nucleotide metabolic processGO:00091171610.010
purine nucleoside triphosphate catabolic processGO:00091461080.010
covalent chromatin modificationGO:00165691060.010
eye developmentGO:00016543230.010
establishment of localization in cellGO:00516494020.010
regulation of response to dna damage stimulusGO:2001020230.010
purine ribonucleoside catabolic processGO:00461301120.010
epithelial cell developmentGO:00020642740.010
cellular protein localizationGO:00346131600.010
male gamete generationGO:00482322010.010
nucleoside metabolic processGO:00091161270.010

Tie disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.036
nervous system diseaseDOID:86300.020
renal tubular transport diseaseDOID:44700.020
kidney diseaseDOID:55700.020
urinary system diseaseDOID:1800.020
disease of metabolismDOID:001466700.012
disease of cellular proliferationDOID:1456600.011
cancerDOID:16200.011
cardiovascular system diseaseDOID:128700.011
organ system cancerDOID:005068600.010