IMP: Integrative Multi-species Prediction

Drosophila melanogaster

211 known processes

chb (Dmel_CG32435)

chromosome bows

(Aliases: mast/orbit,orbit/MAST,anon-WO0104295,MESR7,MAST/Orbit,Dmel\CG32435,orbit/mast,v40,NEST:bs28g05,Orbit/MAST,CG32435,DMAP160,BcDNA:LD31673,CLASP,NEST:bs13a06,chb(v40),Orbit,NEST:bs17d05,Mast,Orbit/Mast,MAST,clasp,orbit,0686/07,mast)

FLYBASE: FBgn0021760
Entrez: 43901
UniProtKB: Q9NBD7

Process Predictions
Disease Predictions

chb biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
growth	GO:0040007	359	0.990	Worm
oocyte differentiation	GO:0009994	145	0.976
centrosome cycle	GO:0007098	137	0.972
organelle assembly	GO:0070925	198	0.967
microtubule organizing center organization	GO:0031023	168	0.955
cell division	GO:0051301	248	0.955
centrosome organization	GO:0051297	163	0.942
nuclear division	GO:0000280	332	0.934
organelle localization	GO:0051640	148	0.898
positive regulation of cellular component organization	GO:0051130	156	0.898
cell proliferation	GO:0008283	299	0.859
regulation of synapse organization	GO:0050807	110	0.820
stem cell division	GO:0017145	69	0.816
negative regulation of cellular component organization	GO:0051129	108	0.810
cytokinesis	GO:0000910	90	0.788	Worm
cell migration	GO:0016477	238	0.764
actin cytoskeleton organization	GO:0030036	206	0.757
negative regulation of developmental process	GO:0051093	201	0.756
male gamete generation	GO:0048232	201	0.747
centrosome duplication	GO:0051298	121	0.730
vesicle mediated transport	GO:0016192	381	0.728
regulation of localization	GO:0032879	275	0.690
embryonic morphogenesis	GO:0048598	206	0.685
regulation of synapse assembly	GO:0051963	94	0.683
maintenance of location	GO:0051235	73	0.667
meiotic nuclear division	GO:0007126	151	0.654
meiotic cell cycle process	GO:1903046	132	0.654
regulation of cellular component biogenesis	GO:0044087	201	0.644
regulation of cytoskeleton organization	GO:0051493	89	0.644
mitotic spindle organization	GO:0007052	220	0.627
spermatid differentiation	GO:0048515	114	0.606
stem cell proliferation	GO:0072089	88	0.587
spermatogenesis	GO:0007283	200	0.573
neuroblast division	GO:0055057	35	0.569
cell motility	GO:0048870	251	0.548
neuroblast proliferation	GO:0007405	74	0.530
spindle organization	GO:0007051	253	0.528
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.526
asymmetric stem cell division	GO:0098722	49	0.514
oocyte development	GO:0048599	124	0.496
negative regulation of signaling	GO:0023057	219	0.488
cellularization	GO:0007349	90	0.484
organelle fission	GO:0048285	340	0.465
regulation of synapse structure and activity	GO:0050803	128	0.451
appendage morphogenesis	GO:0035107	397	0.449
establishment of organelle localization	GO:0051656	122	0.449
meiosis i	GO:0007127	59	0.448
neurological system process	GO:0050877	358	0.447
reproductive structure development	GO:0048608	74	0.445
microtubule based movement	GO:0007018	51	0.436
actin filament organization	GO:0007015	126	0.424
regulation of protein metabolic process	GO:0051246	256	0.407
negative regulation of cell communication	GO:0010648	223	0.390
regulation of organelle organization	GO:0033043	196	0.382
oocyte axis specification	GO:0007309	108	0.378
spindle assembly	GO:0051225	80	0.376
development of primary sexual characteristics	GO:0045137	50	0.371
developmental growth	GO:0048589	280	0.369	Worm
actin filament based process	GO:0030029	220	0.368
nucleus localization	GO:0051647	34	0.349
neural precursor cell proliferation	GO:0061351	75	0.339
mitotic nuclear division	GO:0007067	213	0.335
synapse assembly	GO:0007416	143	0.334
stem cell development	GO:0048864	79	0.328
regulation of microtubule based process	GO:0032886	49	0.326
wnt signaling pathway	GO:0016055	98	0.317
negative regulation of signal transduction	GO:0009968	206	0.303
single organism behavior	GO:0044708	391	0.298
regulation of mitosis	GO:0007088	56	0.298
mitotic centrosome separation	GO:0007100	8	0.294
embryonic pattern specification	GO:0009880	174	0.293
sensory perception	GO:0007600	196	0.282
embryo development ending in birth or egg hatching	GO:0009792	152	0.279	Worm
stem cell maintenance	GO:0019827	67	0.276
endocytosis	GO:0006897	310	0.268
sister chromatid segregation	GO:0000819	92	0.261
positive regulation of cellular protein metabolic process	GO:0032270	118	0.257
female meiotic division	GO:0007143	70	0.256
regulation of cell differentiation	GO:0045595	302	0.253
ovarian fusome organization	GO:0030723	11	0.244
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.242
macromolecular complex assembly	GO:0065003	256	0.235
regulation of protein modification process	GO:0031399	112	0.234
determination of adult lifespan	GO:0008340	137	0.231
asymmetric cell division	GO:0008356	37	0.228
cellular component disassembly	GO:0022411	46	0.228
microtubule depolymerization	GO:0007019	25	0.225
gland morphogenesis	GO:0022612	145	0.222
positive regulation of transport	GO:0051050	92	0.220
positive regulation of organelle organization	GO:0010638	65	0.216
regulation of developmental growth	GO:0048638	174	0.207	Worm
negative regulation of nervous system development	GO:0051961	92	0.207
negative regulation of response to stimulus	GO:0048585	258	0.206
developmental maturation	GO:0021700	172	0.203
negative regulation of phosphate metabolic process	GO:0045936	45	0.198
negative regulation of growth	GO:0045926	84	0.190
vesicle organization	GO:0016050	44	0.189
regulation of chromosome segregation	GO:0051983	32	0.186
protein transport	GO:0015031	155	0.185
dendrite development	GO:0016358	204	0.185
salivary gland development	GO:0007431	162	0.180
larval development	GO:0002164	104	0.180	Worm
negative regulation of synapse assembly	GO:0051964	39	0.180
mitotic sister chromatid segregation	GO:0000070	87	0.176
programmed cell death	GO:0012501	257	0.171
appendage development	GO:0048736	401	0.171
reproductive system development	GO:0061458	74	0.168
protein modification process	GO:0036211	438	0.165
meiotic cell cycle	GO:0051321	171	0.164
chromosome segregation	GO:0007059	157	0.162
cell death	GO:0008219	279	0.161
cellular catabolic process	GO:0044248	372	0.157
actin filament bundle assembly	GO:0051017	26	0.154
catabolic process	GO:0009056	409	0.154
regulation of molecular function	GO:0065009	217	0.154
oocyte construction	GO:0007308	112	0.152
regulation of cell cycle	GO:0051726	291	0.147
organic substance catabolic process	GO:1901575	308	0.146
negative regulation of developmental growth	GO:0048640	64	0.145
wing disc morphogenesis	GO:0007472	344	0.141
chromosome organization	GO:0051276	360	0.140
regulation of transport	GO:0051049	181	0.140
cellular macromolecular complex assembly	GO:0034622	153	0.138	Human
maintenance of location in cell	GO:0051651	28	0.136
cellular protein modification process	GO:0006464	438	0.136
regionalization	GO:0003002	416	0.134
developmental programmed cell death	GO:0010623	138	0.133
germ line stem cell division	GO:0042078	25	0.127
peripheral nervous system development	GO:0007422	52	0.126
cytoplasmic transport	GO:0016482	130	0.126	Worm
exocrine system development	GO:0035272	162	0.123
meiotic cytokinesis	GO:0033206	33	0.123
asymmetric neuroblast division	GO:0055059	33	0.123
actin filament bundle organization	GO:0061572	28	0.122
gonad development	GO:0008406	50	0.122
death	GO:0016265	284	0.120
post embryonic appendage morphogenesis	GO:0035120	385	0.120
cellular protein localization	GO:0034613	160	0.120
golgi localization	GO:0051645	2	0.119
microtubule polymerization or depolymerization	GO:0031109	39	0.119
somatic stem cell division	GO:0048103	37	0.119
protein modification by small protein conjugation or removal	GO:0070647	106	0.119
sensory perception of mechanical stimulus	GO:0050954	72	0.111
negative regulation of cytoskeleton organization	GO:0051494	30	0.109
response to abiotic stimulus	GO:0009628	341	0.107
positive regulation of macromolecule metabolic process	GO:0010604	405	0.106
regulation of microtubule depolymerization	GO:0031114	24	0.105
intracellular transport	GO:0046907	228	0.104	Worm
protein modification by small protein conjugation	GO:0032446	79	0.104
regulation of growth	GO:0040008	233	0.104	Worm
anatomical structure homeostasis	GO:0060249	97	0.103
locomotory behavior	GO:0007626	176	0.102
protein polymerization	GO:0051258	42	0.101	Human
macromolecular complex disassembly	GO:0032984	37	0.100
cystoblast division	GO:0007282	10	0.099
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.097
regulation of vesicle mediated transport	GO:0060627	59	0.097
translation	GO:0006412	69	0.096
regulation of proteasomal protein catabolic process	GO:0061136	39	0.096
regulation of cellular catabolic process	GO:0031329	157	0.094
transcription from rna polymerase ii promoter	GO:0006366	368	0.094
chromosome separation	GO:0051304	42	0.094	Worm
positive regulation of protein metabolic process	GO:0051247	128	0.094
negative regulation of phosphorus metabolic process	GO:0010563	45	0.093
mitotic spindle stabilization	GO:0043148	6	0.093
regulation of nuclear division	GO:0051783	58	0.092
synaptic growth at neuromuscular junction	GO:0051124	119	0.092
single organism intracellular transport	GO:1902582	207	0.092
positive regulation of developmental process	GO:0051094	143	0.088	Worm
organic substance transport	GO:0071702	257	0.087
positive regulation of cell cycle	GO:0045787	43	0.086
phosphorylation	GO:0016310	294	0.085
nuclear migration	GO:0007097	20	0.083
regulation of microtubule cytoskeleton organization	GO:0070507	41	0.083
cellular macromolecule catabolic process	GO:0044265	136	0.083
gland development	GO:0048732	191	0.082
regulation of tube architecture open tracheal system	GO:0035152	68	0.081
localization of cell	GO:0051674	257	0.081
apoptotic process	GO:0006915	159	0.081
posttranscriptional regulation of gene expression	GO:0010608	145	0.080
eye photoreceptor cell differentiation	GO:0001754	145	0.080
eye antennal disc morphogenesis	GO:0007455	34	0.080
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.079
negative regulation of cell proliferation	GO:0008285	69	0.078
neuronal stem cell division	GO:0036445	35	0.078
protein localization	GO:0008104	284	0.078
regulation of cellular protein metabolic process	GO:0032268	243	0.076
negative regulation of cell differentiation	GO:0045596	143	0.074
cell maturation	GO:0048469	144	0.074
salivary gland morphogenesis	GO:0007435	145	0.073
regulation of cell migration	GO:0030334	22	0.073
cellular component assembly involved in morphogenesis	GO:0010927	151	0.073
aromatic compound catabolic process	GO:0019439	166	0.072
spermatid development	GO:0007286	98	0.072
germarium derived egg chamber formation	GO:0007293	101	0.072
pole cell formation	GO:0007279	19	0.070
mitotic sister chromatid separation	GO:0051306	30	0.070	Worm
intracellular signal transduction	GO:0035556	300	0.069
negative regulation of intracellular signal transduction	GO:1902532	57	0.069
regulation of dendrite morphogenesis	GO:0048814	28	0.068
dendrite morphogenesis	GO:0048813	199	0.067
establishment or maintenance of cell polarity	GO:0007163	167	0.067
germline stem cell asymmetric division	GO:0098728	15	0.067
macromolecule catabolic process	GO:0009057	161	0.066
response to organic substance	GO:0010033	284	0.066
regulation of cell division	GO:0051302	72	0.066
organelle transport along microtubule	GO:0072384	7	0.065
positive regulation of signaling	GO:0023056	243	0.065
regulation of mitotic sister chromatid separation	GO:0010965	28	0.064
regulation of cellular protein catabolic process	GO:1903362	44	0.063
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.063
homeostatic process	GO:0042592	199	0.062
germarium derived oocyte differentiation	GO:0030706	29	0.062
purine ribonucleotide catabolic process	GO:0009154	109	0.062
respiratory system development	GO:0060541	213	0.062
negative regulation of organelle organization	GO:0010639	56	0.061
regulation of catabolic process	GO:0009894	170	0.059
positive regulation of cell projection organization	GO:0031346	29	0.059
segmentation	GO:0035282	207	0.058
negative regulation of cellular protein metabolic process	GO:0032269	85	0.058
segment polarity determination	GO:0007367	25	0.057
nucleus organization	GO:0006997	45	0.057
body morphogenesis	GO:0010171	2	0.056
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.056
sex differentiation	GO:0007548	81	0.056
microtubule bundle formation	GO:0001578	27	0.055	Human
positive regulation of cellular biosynthetic process	GO:0031328	316	0.055
detection of stimulus	GO:0051606	156	0.055
regulation of cell proliferation	GO:0042127	163	0.055
cell recognition	GO:0008037	102	0.053
embryonic development via the syncytial blastoderm	GO:0001700	148	0.053
purine ribonucleoside metabolic process	GO:0046128	127	0.053
protein complex biogenesis	GO:0070271	201	0.053
regulation of notch signaling pathway	GO:0008593	100	0.052
positive regulation of cell communication	GO:0010647	250	0.052
regulation of protein complex disassembly	GO:0043244	29	0.052
negative regulation of protein metabolic process	GO:0051248	85	0.052
cellular nitrogen compound catabolic process	GO:0044270	165	0.051
modification dependent macromolecule catabolic process	GO:0043632	79	0.051
negative regulation of cell development	GO:0010721	62	0.051
positive regulation of gene expression	GO:0010628	290	0.051
regulation of proteolysis involved in cellular protein catabolic process	GO:1903050	44	0.051
mesoderm development	GO:0007498	78	0.051
sensory perception of sound	GO:0007605	56	0.050
regulation of intracellular signal transduction	GO:1902531	236	0.049
protein catabolic process	GO:0030163	101	0.049
regulation of hydrolase activity	GO:0051336	97	0.049
single organism membrane organization	GO:0044802	93	0.049
positive regulation of response to stimulus	GO:0048584	323	0.048
ribonucleoside monophosphate catabolic process	GO:0009158	39	0.048
positive regulation of nervous system development	GO:0051962	69	0.048
regulation of phosphorus metabolic process	GO:0051174	210	0.048
establishment of protein localization to organelle	GO:0072594	62	0.048
modification dependent protein catabolic process	GO:0019941	78	0.048
germ line stem cell maintenance	GO:0030718	50	0.048
positive regulation of rna metabolic process	GO:0051254	271	0.048
regulation of cellular component movement	GO:0051270	42	0.047
carbohydrate derivative catabolic process	GO:1901136	118	0.047
positive regulation of signal transduction	GO:0009967	223	0.047
regulation of nervous system development	GO:0051960	248	0.046
tissue death	GO:0016271	102	0.046
cell projection assembly	GO:0030031	94	0.046
positive regulation of protein modification process	GO:0031401	58	0.046
positive regulation of transcription dna templated	GO:0045893	266	0.046
organonitrogen compound metabolic process	GO:1901564	318	0.045
protein complex disassembly	GO:0043241	36	0.044
regulation of protein complex assembly	GO:0043254	42	0.044
histolysis	GO:0007559	102	0.044
endomembrane system organization	GO:0010256	119	0.044
cellular homeostasis	GO:0019725	80	0.044
protein depolymerization	GO:0051261	31	0.043
dna conformation change	GO:0071103	105	0.043
central nervous system development	GO:0007417	201	0.042
synapse organization	GO:0050808	196	0.042
nucleotide metabolic process	GO:0009117	161	0.042
spindle localization	GO:0051653	22	0.042
regulation of cell morphogenesis	GO:0022604	163	0.042
oocyte dorsal ventral axis specification	GO:0007310	34	0.042
regulation of cellular localization	GO:0060341	136	0.041
establishment of protein localization	GO:0045184	163	0.041
digestive tract development	GO:0048565	149	0.041
regulation of cell motility	GO:2000145	23	0.041
cardiovascular system development	GO:0072358	82	0.041
dorsal ventral pattern formation	GO:0009953	133	0.041
negative regulation of catalytic activity	GO:0043086	42	0.041
positive regulation of cell cycle process	GO:0090068	28	0.040
protein localization to nucleus	GO:0034504	55	0.040
signal transduction by phosphorylation	GO:0023014	107	0.039
establishment of localization in cell	GO:0051649	402	0.039
organophosphate metabolic process	GO:0019637	195	0.039
positive regulation of proteolysis involved in cellular protein catabolic process	GO:1903052	24	0.038
purine ribonucleoside triphosphate catabolic process	GO:0009207	108	0.038
regulation of protein transport	GO:0051223	57	0.038
positive regulation of cytoskeleton organization	GO:0051495	21	0.038
embryonic organ development	GO:0048568	50	0.038
open tracheal system development	GO:0007424	204	0.038
negative regulation of protein modification process	GO:0031400	29	0.037
positive regulation of cellular component biogenesis	GO:0044089	80	0.037
fusome organization	GO:0045478	13	0.037
positive regulation of cell development	GO:0010720	61	0.037
nuclear transport	GO:0051169	72	0.037
epithelial cell migration	GO:0010631	148	0.036
nucleoside triphosphate metabolic process	GO:0009141	120	0.036
regulation of epithelial cell proliferation	GO:0050678	4	0.036
establishment of nucleus localization	GO:0040023	26	0.036
forebrain development	GO:0030900	2	0.036
regulation of proteolysis	GO:0030162	87	0.035
purine ribonucleoside catabolic process	GO:0046130	112	0.035
endosomal transport	GO:0016197	44	0.035
regulation of intracellular transport	GO:0032386	64	0.035
centriole replication	GO:0007099	24	0.035
regulation of protein catabolic process	GO:0042176	55	0.035
blastoderm segmentation	GO:0007350	159	0.034
regulation of phosphate metabolic process	GO:0019220	210	0.034
nucleoside phosphate metabolic process	GO:0006753	162	0.034
regulation of phosphorylation	GO:0042325	147	0.034
positive regulation of cellular catabolic process	GO:0031331	95	0.034
sperm individualization	GO:0007291	48	0.033
positive regulation of axonogenesis	GO:0050772	2	0.033
imaginal disc derived wing morphogenesis	GO:0007476	337	0.033
aging	GO:0007568	143	0.033
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.032
regulation of catalytic activity	GO:0050790	185	0.032
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.032
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.032
negative regulation of multicellular organismal process	GO:0051241	142	0.032
oocyte anterior posterior axis specification	GO:0007314	72	0.031
regulation of cellular ketone metabolic process	GO:0010565	3	0.031
imaginal disc derived appendage development	GO:0048737	399	0.031
positive regulation of cellular amine metabolic process	GO:0033240	0	0.031
protein maturation	GO:0051604	71	0.031
cytoskeleton dependent intracellular transport	GO:0030705	44	0.030
protein targeting	GO:0006605	64	0.030
cellular response to chemical stimulus	GO:0070887	199	0.030
extracellular structure organization	GO:0043062	46	0.030
attachment of spindle microtubules to kinetochore	GO:0008608	5	0.030
digestive tract morphogenesis	GO:0048546	127	0.029
positive regulation of cell proliferation	GO:0008284	47	0.029
nucleoside metabolic process	GO:0009116	127	0.029
regulation of wnt signaling pathway	GO:0030111	68	0.029
oocyte maturation	GO:0001556	3	0.029
ovarian follicle cell development	GO:0030707	248	0.029
microtubule based transport	GO:0010970	42	0.029
muscle structure development	GO:0061061	224	0.029
regulation of anatomical structure morphogenesis	GO:0022603	242	0.029
phagocytosis	GO:0006909	215	0.028
nucleoside triphosphate catabolic process	GO:0009143	108	0.028
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.028
mapk cascade	GO:0000165	107	0.028
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.028
negative regulation of phosphorylation	GO:0042326	35	0.028
spindle assembly involved in mitosis	GO:0090307	50	0.028
neuron projection guidance	GO:0097485	241	0.027
chemotaxis	GO:0006935	249	0.027
anterior posterior axis specification	GO:0009948	109	0.027
ribonucleoside metabolic process	GO:0009119	127	0.027
negative regulation of cellular metabolic process	GO:0031324	382	0.027
oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0051663	12	0.027
striated muscle cell differentiation	GO:0051146	90	0.027
mitotic cytokinesis	GO:0000281	50	0.026	Worm
response to extracellular stimulus	GO:0009991	116	0.026
pseudocleavage involved in syncytial blastoderm formation	GO:0030589	9	0.026
regulation of hemocyte proliferation	GO:0035206	37	0.026
regulation of cell shape	GO:0008360	113	0.026
detection of external stimulus	GO:0009581	66	0.026
erk1 and erk2 cascade	GO:0070371	39	0.026
digestive system development	GO:0055123	149	0.025
carbohydrate derivative metabolic process	GO:1901135	217	0.025
pole plasm rna localization	GO:0007316	52	0.025
nucleotide catabolic process	GO:0009166	109	0.025
cation homeostasis	GO:0055080	51	0.025
extrinsic apoptotic signaling pathway	GO:0097191	1	0.025
myofibril assembly	GO:0030239	36	0.025
positive regulation of biosynthetic process	GO:0009891	316	0.025
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.024
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.024
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.024
regulation of mapk cascade	GO:0043408	92	0.024
regulation of actin cytoskeleton organization	GO:0032956	42	0.024
female germ line stem cell asymmetric division	GO:0048132	14	0.024
response to light stimulus	GO:0009416	124	0.024
stem cell differentiation	GO:0048863	117	0.024
regulation of metaphase anaphase transition of cell cycle	GO:1902099	26	0.024
single organism catabolic process	GO:0044712	228	0.024
heterocycle catabolic process	GO:0046700	166	0.024
positive regulation of phosphorylation	GO:0042327	87	0.023
anterior posterior axis specification embryo	GO:0008595	103	0.023
cellular macromolecule localization	GO:0070727	220	0.023
hair cell differentiation	GO:0035315	47	0.023
glycosyl compound metabolic process	GO:1901657	127	0.023
cell substrate adhesion	GO:0031589	10	0.023
germ band extension	GO:0007377	11	0.023
regulation of sequestering of calcium ion	GO:0051282	3	0.023
purine ribonucleoside monophosphate metabolic process	GO:0009167	50	0.022
cell cycle phase transition	GO:0044770	140	0.022
axon development	GO:0061564	297	0.022
purine nucleotide catabolic process	GO:0006195	109	0.022
epithelial cell development	GO:0002064	274	0.022
regulation of cell cycle phase transition	GO:1901987	130	0.022
dorsal closure	GO:0007391	79	0.022
glial cell differentiation	GO:0010001	35	0.022
regulation of cellular amino acid metabolic process	GO:0006521	0	0.022
cognition	GO:0050890	141	0.022
purine nucleoside triphosphate metabolic process	GO:0009144	119	0.021
regulation of ras protein signal transduction	GO:0046578	93	0.021
regulation of neuron projection development	GO:0010975	69	0.021
multicellular organismal aging	GO:0010259	140	0.021
taxis	GO:0042330	304	0.021
positive regulation of catabolic process	GO:0009896	105	0.021
nitrogen compound transport	GO:0071705	85	0.021
organic cyclic compound catabolic process	GO:1901361	168	0.021
maintenance of protein location	GO:0045185	28	0.021
protein localization to organelle	GO:0033365	82	0.021
nucleoside phosphate catabolic process	GO:1901292	110	0.021
cellular protein complex disassembly	GO:0043624	35	0.021
salivary gland histolysis	GO:0035070	88	0.020
cellular amine metabolic process	GO:0044106	12	0.020
multicellular organismal homeostasis	GO:0048871	41	0.020
gastrulation involving germ band extension	GO:0010004	36	0.020
axonogenesis	GO:0007409	290	0.020
regulation of cyclin dependent protein serine threonine kinase activity	GO:0000079	3	0.020
purine nucleoside triphosphate catabolic process	GO:0009146	108	0.020
canonical wnt signaling pathway	GO:0060070	21	0.020
regulation of cellular amine metabolic process	GO:0033238	3	0.020
regulation of cell morphogenesis involved in differentiation	GO:0010769	61	0.020
negative regulation of protein depolymerization	GO:1901880	23	0.020
adult behavior	GO:0030534	137	0.020
establishment or maintenance of microtubule cytoskeleton polarity	GO:0030951	41	0.019
eye morphogenesis	GO:0048592	260	0.019
regulation of mitotic sister chromatid segregation	GO:0033047	28	0.019
purine containing compound metabolic process	GO:0072521	155	0.019
regulation of locomotion	GO:0040012	42	0.019
germarium derived oocyte fate determination	GO:0007294	26	0.019
tripartite regional subdivision	GO:0007351	103	0.019
regulation of multicellular organismal development	GO:2000026	414	0.019
apoptotic cell clearance	GO:0043277	14	0.019
pole cell development	GO:0007277	26	0.019
protein complex assembly	GO:0006461	200	0.019
positive regulation of mitotic cell cycle	GO:0045931	34	0.019
organelle fusion	GO:0048284	46	0.018
negative regulation of cell migration	GO:0030336	5	0.018
nucleobase containing small molecule metabolic process	GO:0055086	174	0.018
mitotic cell cycle embryonic	GO:0045448	38	0.018
cellular protein complex assembly	GO:0043623	71	0.018	Human
ribonucleoside catabolic process	GO:0042454	112	0.018
regulation of sister chromatid segregation	GO:0033045	28	0.018
ribonucleoprotein complex assembly	GO:0022618	23	0.018
rna localization	GO:0006403	115	0.018
metaphase anaphase transition of mitotic cell cycle	GO:0007091	28	0.018
positive regulation of intracellular transport	GO:0032388	42	0.018
detection of abiotic stimulus	GO:0009582	66	0.018
protein phosphorylation	GO:0006468	169	0.017
cellular response to abiotic stimulus	GO:0071214	58	0.017
ovarian nurse cell to oocyte transport	GO:0007300	27	0.017
positive regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032436	19	0.017
receptor mediated endocytosis	GO:0006898	21	0.017
small gtpase mediated signal transduction	GO:0007264	88	0.017
meiotic spindle organization	GO:0000212	36	0.017
tissue homeostasis	GO:0001894	36	0.017
morphogenesis of an epithelium	GO:0002009	276	0.017
proteasomal protein catabolic process	GO:0010498	59	0.017
muscle cell development	GO:0055001	50	0.017
regulation of translation	GO:0006417	56	0.016
striated muscle cell development	GO:0055002	50	0.016
positive regulation of protein catabolic process	GO:0045732	34	0.016
response to other organism	GO:0051707	293	0.016
ubiquitin dependent protein catabolic process	GO:0006511	78	0.016
skin development	GO:0043588	65	0.016
organonitrogen compound catabolic process	GO:1901565	128	0.016
ribonucleotide metabolic process	GO:0009259	145	0.016
positive regulation of phosphorus metabolic process	GO:0010562	139	0.016
tube development	GO:0035295	244	0.016
regulation of actin filament based process	GO:0032970	42	0.015
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.015
membrane disassembly	GO:0030397	4	0.015
ras protein signal transduction	GO:0007265	88	0.015
ribonucleoprotein complex subunit organization	GO:0071826	28	0.015
regulation of mitotic metaphase anaphase transition	GO:0030071	26	0.015
regulation of protein localization	GO:0032880	76	0.015
organophosphate catabolic process	GO:0046434	112	0.015
response to nutrient levels	GO:0031667	114	0.015
telencephalon development	GO:0021537	2	0.015
proteolysis	GO:0006508	192	0.015
glial cell development	GO:0021782	27	0.015
skeletal muscle tissue development	GO:0007519	13	0.015
positive regulation of developmental growth	GO:0048639	62	0.015	Worm
male meiosis cytokinesis	GO:0007112	26	0.015
motor neuron axon guidance	GO:0008045	58	0.014
axon guidance	GO:0007411	233	0.014
purine containing compound catabolic process	GO:0072523	112	0.014
nucleoside monophosphate metabolic process	GO:0009123	52	0.014

chb disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
congenital nervous system abnormality	DOID:2490	0.022
physical disorder	DOID:0080015	0.022
disease of anatomical entity	DOID:7	0.022
cancer	DOID:162	0.020
disease of cellular proliferation	DOID:14566	0.020

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