Drosophila melanogaster

16 known processes

Smc5 (Dmel_CG32438)

CG32438 gene product from transcript CG32438-RE

(Aliases: SMC5,DmSMC5,Dmel\CG32438,CG32438,CG7783)

Smc5 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
dna repairGO:0006281540.884
mitotic recombinationGO:000631220.489
dna metabolic processGO:00062592270.486
response to uvGO:0009411240.373
mitotic dna damage checkpointGO:0044773740.372
cellular response to dna damage stimulusGO:00069742230.350
regulation of response to stressGO:00801342000.297
recombinational repairGO:0000725130.281
negative regulation of cellular metabolic processGO:00313243820.268
regulation of mitotic cell cycleGO:00073461900.265
double strand break repairGO:0006302260.263
response to radiationGO:00093141550.256
mitotic g2 dna damage checkpointGO:0007095690.249
negative regulation of cell cycle phase transitionGO:19019881030.222
double strand break repair via homologous recombinationGO:0000724130.212
dna double strand break processingGO:000072930.194
g2 dna damage checkpointGO:0031572690.183
dna recombinationGO:0006310320.174
response to alkaloidGO:0043279260.167
chromosome organizationGO:00512763600.159
dna damage checkpointGO:0000077780.153
regulation of cellular response to stressGO:0080135890.151
response to abiotic stimulusGO:00096283410.149
regulation of mitotic cell cycle phase transitionGO:19019901300.148
cellular macromolecule catabolic processGO:00442651360.143
dna duplex unwindingGO:0032508160.142
dna conformation changeGO:00711031050.134
regulation of dna recombinationGO:000001840.134
double strand break repair via synthesis dependent strand annealingGO:004500360.127
nucleotide excision repairGO:000628980.119
response to light stimulusGO:00094161240.117
mitotic cell cycle phase transitionGO:00447721380.111
cell cycle checkpointGO:0000075950.090
regulation of dna repairGO:000628250.090
negative regulation of macromolecule biosynthetic processGO:00105582700.089
response to ionizing radiationGO:0010212320.087
mitotic nuclear divisionGO:00070672130.085
nucleobase containing compound catabolic processGO:00346551650.085
macromolecule catabolic processGO:00090571610.083
aromatic compound catabolic processGO:00194391660.082
organic substance catabolic processGO:19015753080.081
homeostatic processGO:00425921990.081
mitotic dna integrity checkpointGO:0044774750.081
cellular catabolic processGO:00442483720.079
dna catabolic processGO:0006308160.077
chromatin silencingGO:0006342760.076
negative regulation of nucleobase containing compound metabolic processGO:00459342610.075
small molecule metabolic processGO:00442813050.075
meiosis iGO:0007127590.074
telomere maintenanceGO:0000723210.072
postreplication repairGO:000630120.072
cell proliferationGO:00082832990.068
negative regulation of nitrogen compound metabolic processGO:00511722650.068
exocrine system developmentGO:00352721620.065
cellular response to abiotic stimulusGO:0071214580.064
regulation of response to dna damage stimulusGO:2001020230.064
regulation of cell cycleGO:00517262910.063
cellular response to chemical stimulusGO:00708871990.061
translesion synthesisGO:001998520.061
catabolic processGO:00090564090.059
regulation of gene expression epigeneticGO:00400291280.059
programmed cell deathGO:00125012570.059
double strand break repair via nonhomologous end joiningGO:000630350.057
negative regulation of mitotic cell cycle phase transitionGO:19019911030.052
negative regulation of cellular biosynthetic processGO:00313272770.052
cellular response to radiationGO:0071478520.051
protein catabolic processGO:00301631010.050
response to nitrogen compoundGO:1901698900.049
proteolysisGO:00065081920.048
regulation of cellular protein metabolic processGO:00322682430.047
anatomical structure homeostasisGO:0060249970.047
regionalizationGO:00030024160.046
cell agingGO:000756920.045
negative regulation of biosynthetic processGO:00098902770.045
innate immune responseGO:00450871440.045
response to purine containing compoundGO:0014074120.045
salivary gland developmentGO:00074311620.044
dna replicationGO:0006260480.044
deathGO:00162652840.044
protein modification by small protein conjugation or removalGO:00706471060.042
cellular protein modification processGO:00064644380.040
organic cyclic compound catabolic processGO:19013611680.040
reciprocal meiotic recombinationGO:0007131190.039
behavioral response to ethanolGO:0048149490.038
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.038
regulation of cell developmentGO:00602842150.037
protein modification processGO:00362114380.036
response to organic cyclic compoundGO:0014070890.036
cellular nitrogen compound catabolic processGO:00442701650.035
meiotic chromosome segregationGO:0045132590.035
heterocycle catabolic processGO:00467001660.034
regulation of protein metabolic processGO:00512462560.034
regulation of cell cycle processGO:00105641810.034
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.034
negative regulation of mitotic cell cycleGO:00459301090.032
negative regulation of cellular protein metabolic processGO:0032269850.032
telomere maintenance via recombinationGO:000072210.032
central nervous system developmentGO:00074172010.032
establishment of localization in cellGO:00516494020.032
dna synthesis involved in dna repairGO:000073150.031
organelle fissionGO:00482853400.031
cellular response to ionizing radiationGO:0071479150.030
negative regulation of gene expressionGO:00106293870.029
mitotic cell cycle checkpointGO:0007093880.028
regulation of double strand break repairGO:200077930.027
regulation of neural precursor cell proliferationGO:2000177350.027
dna geometric changeGO:0032392160.026
cellular macromolecule localizationGO:00707272200.026
purine ribonucleoside monophosphate catabolic processGO:0009169380.026
regulation of chromatin silencingGO:0031935360.026
glycosyl compound metabolic processGO:19016571270.025
metal ion transportGO:0030001740.025
chromosome separationGO:0051304420.024
regulation of multicellular organismal developmentGO:20000264140.024
imaginal disc derived appendage morphogenesisGO:00351143950.023
axonogenesisGO:00074092900.023
negative regulation of cell cycleGO:00457861160.022
organophosphate metabolic processGO:00196371950.022
response to organonitrogen compoundGO:0010243750.022
single organism biosynthetic processGO:00447112060.022
regulation of defense responseGO:00313471020.022
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.022
positive regulation of nitrogen compound metabolic processGO:00511733540.021
negative regulation of response to stimulusGO:00485852580.020
cation transportGO:00068121100.020
nuclear divisionGO:00002803320.020
vesicle mediated transportGO:00161923810.020
regulation of cell differentiationGO:00455953020.019
dna integrity checkpointGO:0031570810.019
cation transmembrane transportGO:0098655880.019
body morphogenesisGO:001017120.019
telomere cappingGO:0016233110.019
negative regulation of transcription dna templatedGO:00458922370.019
immune responseGO:00069552460.018
organonitrogen compound metabolic processGO:19015643180.018
salivary gland cell autophagic cell deathGO:0035071830.018
ribonucleotide metabolic processGO:00092591450.018
agingGO:00075681430.018
non recombinational repairGO:000072670.017
negative regulation of protein metabolic processGO:0051248850.017
single organism behaviorGO:00447083910.017
mitotic g2 m transition checkpointGO:0044818700.017
regulation of gene silencingGO:0060968630.017
gene silencingGO:00164581380.017
cell deathGO:00082192790.017
negative regulation of developmental processGO:00510932010.017
meiotic cell cycle processGO:19030461320.016
dorsal ventral pattern formationGO:00099531330.016
gland developmentGO:00487321910.016
intracellular transportGO:00469072280.016
ribonucleoside metabolic processGO:00091191270.016
negative regulation of dna recombinationGO:004591020.016
reciprocal dna recombinationGO:0035825190.016
negative regulation of cell cycle processGO:00109481090.015
regulation of cell proliferationGO:00421271630.015
rna localizationGO:00064031150.015
sex determinationGO:0007530180.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
dna packagingGO:0006323910.015
establishment of protein localizationGO:00451841630.014
cell cycle phase transitionGO:00447701400.014
positive regulation of macromolecule metabolic processGO:00106044050.014
gland morphogenesisGO:00226121450.014
protein ubiquitinationGO:0016567700.014
regulation of immune system processGO:00026821760.014
signal transduction in response to dna damageGO:004277030.014
ion transportGO:00068111450.014
ribonucleoside catabolic processGO:00424541120.013
nucleoside phosphate metabolic processGO:00067531620.013
cellular protein catabolic processGO:0044257830.013
regulation of dna metabolic processGO:0051052340.013
mitotic sister chromatid segregationGO:0000070870.013
tissue morphogenesisGO:00487292970.013
response to organic substanceGO:00100332840.013
dendrite developmentGO:00163582040.013
endocytosisGO:00068973100.013
oxoacid metabolic processGO:00434361030.013
positive regulation of gene expressionGO:00106282900.013
positive regulation of cellular biosynthetic processGO:00313283160.012
positive regulation of macromolecule biosynthetic processGO:00105572830.012
regulation of programmed cell deathGO:00430671520.012
meiotic cell cycleGO:00513211710.012
ribose phosphate metabolic processGO:00196931450.012
defense responseGO:00069523000.012
regulation of cell divisionGO:0051302720.012
regulation of apoptotic processGO:00429811300.012
negative regulation of cell differentiationGO:00455961430.012
dorsal ventral axis specificationGO:0009950660.011
regulation of innate immune responseGO:0045088710.011
negative regulation of dna metabolic processGO:0051053120.011
imaginal disc derived wing morphogenesisGO:00074763370.011
negative regulation of cell deathGO:0060548810.011
negative regulation of cell developmentGO:0010721620.011
positive regulation of mitotic cell cycleGO:0045931340.011
proteolysis involved in cellular protein catabolic processGO:0051603830.011
cellular response to oxygen containing compoundGO:1901701790.011
meiotic nuclear divisionGO:00071261510.011
chromatin remodelingGO:0006338720.011
purine nucleoside catabolic processGO:00061521120.011
regulation of cell deathGO:00109411730.011
histolysisGO:00075591020.011
immune system processGO:00023763470.011
nucleotide metabolic processGO:00091171610.010
macromolecular complex assemblyGO:00650032560.010
alternative mrna splicing via spliceosomeGO:0000380600.010
salivary gland morphogenesisGO:00074351450.010
nucleobase containing small molecule metabolic processGO:00550861740.010
negative regulation of cell communicationGO:00106482230.010
purine nucleoside monophosphate catabolic processGO:0009128380.010
regulation of phosphorus metabolic processGO:00511742100.010
positive regulation of response to stimulusGO:00485843230.010
sister chromatid segregationGO:0000819920.010
regulation of peptidase activityGO:0052547390.010
muscle organ developmentGO:00075171270.010

Smc5 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.024
cancerDOID:16200.024