Drosophila melanogaster

78 known processes

HP1e (Dmel_CG8120)

CG8120 gene product from transcript CG8120-RA

(Aliases: HP1E,CG8120,Dmel\CG8120)

HP1e biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mitotic cell cycle phase transitionGO:19019901300.197
regulation of cell cycle phase transitionGO:19019871300.139
regulation of cell cycle processGO:00105641810.084
negative regulation of mitotic cell cycleGO:00459301090.081
negative regulation of cell cycle processGO:00109481090.080
negative regulation of mitotic cell cycle phase transitionGO:19019911030.077
cell cycle phase transitionGO:00447701400.066
cell cycle checkpointGO:0000075950.063
negative regulation of cell cycle phase transitionGO:19019881030.059
regulation of protein metabolic processGO:00512462560.058
organonitrogen compound metabolic processGO:19015643180.057
regulation of mitotic cell cycleGO:00073461900.054
organonitrogen compound biosynthetic processGO:19015661170.050
rrna processingGO:000636430.049
regulation of cell cycleGO:00517262910.049
mitotic cell cycle phase transitionGO:00447721380.049
olfactory learningGO:0008355560.048
Worm
homeostatic processGO:00425921990.043
regionalizationGO:00030024160.041
mitotic cell cycle checkpointGO:0007093880.041
sister chromatid segregationGO:0000819920.040
regulation of molecular functionGO:00650092170.037
mitotic sister chromatid segregationGO:0000070870.035
regulation of catabolic processGO:00098941700.034
small gtpase mediated signal transductionGO:0007264880.034
Worm
regulation of catalytic activityGO:00507901850.032
regulation of cellular amine metabolic processGO:003323830.032
dna templated transcriptional preinitiation complex assemblyGO:0070897200.031
regulation of cellular protein metabolic processGO:00322682430.031
regulation of intracellular signal transductionGO:19025312360.031
Worm
single organism biosynthetic processGO:00447112060.031
chromosome segregationGO:00070591570.031
mitotic nuclear divisionGO:00070672130.030
transcription from rna polymerase ii promoterGO:00063663680.028
chromosome separationGO:0051304420.028
cellular amide metabolic processGO:0043603800.028
mitotic g2 m transition checkpointGO:0044818700.028
dna integrity checkpointGO:0031570810.027
regulation of phosphate metabolic processGO:00192202100.027
regulation of cellular amino acid metabolic processGO:000652100.027
mitotic dna integrity checkpointGO:0044774750.027
cellular response to dna damage stimulusGO:00069742230.027
mitotic sister chromatid separationGO:0051306300.027
single organism catabolic processGO:00447122280.026
regulation of nervous system developmentGO:00519602480.026
cell divisionGO:00513012480.026
single organism behaviorGO:00447083910.026
Worm
regulation of mitotic metaphase anaphase transitionGO:0030071260.025
regulation of response to stressGO:00801342000.024
response to organic substanceGO:00100332840.024
g2 dna damage checkpointGO:0031572690.024
regulation of growthGO:00400082330.023
Worm
response to starvationGO:0042594970.023
positive regulation of catalytic activityGO:00430851180.023
regulation of immune responseGO:00507761180.023
defense response to bacteriumGO:00427421780.023
peptide metabolic processGO:0006518800.023
intracellular signal transductionGO:00355563000.023
Worm
regulation of ras protein signal transductionGO:0046578930.022
Worm
regulation of cellular ketone metabolic processGO:001056530.022
regulation of cellular catabolic processGO:00313291570.022
developmental growthGO:00485892800.022
Worm
protein complex assemblyGO:00064612000.022
oxoacid metabolic processGO:00434361030.021
growthGO:00400073590.021
Worm
dna damage checkpointGO:0000077780.021
regulation of cellular localizationGO:00603411360.021
positive regulation of molecular functionGO:00440931360.021
establishment of localization in cellGO:00516494020.021
positive regulation of signalingGO:00230562430.021
ras protein signal transductionGO:0007265880.021
Worm
kidney developmentGO:000182230.020
detection of chemical stimulus involved in sensory perceptionGO:0050907750.020
embryonic pattern specificationGO:00098801740.020
body morphogenesisGO:001017120.020
small molecule metabolic processGO:00442813050.020
regulation of mitotic sister chromatid segregationGO:0033047280.020
endocytosisGO:00068973100.020
muscle structure developmentGO:00610612240.020
response to other organismGO:00517072930.020
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.019
protein modification processGO:00362114380.019
macromolecular complex assemblyGO:00650032560.019
regulation of proteasomal protein catabolic processGO:0061136390.019
peptide biosynthetic processGO:0043043420.019
amine metabolic processGO:0009308120.019
positive regulation of proteolysisGO:0045862520.019
positive regulation of phosphate metabolic processGO:00459371390.019
regulation of programmed cell deathGO:00430671520.019
protein dna complex subunit organizationGO:0071824860.019
negative regulation of response to stimulusGO:00485852580.018
Worm
response to abiotic stimulusGO:00096283410.018
cellular catabolic processGO:00442483720.018
programmed cell deathGO:00125012570.018
Worm
regulation of sister chromatid segregationGO:0033045280.018
nephron developmentGO:007200630.018
response to nutrient levelsGO:00316671140.018
organelle fissionGO:00482853400.017
cognitionGO:00508901410.017
Worm
positive regulation of apoptotic signaling pathwayGO:200123540.017
metaphase anaphase transition of cell cycleGO:0044784280.017
matingGO:00076181200.017
regulation of cell divisionGO:0051302720.017
cellular amino acid metabolic processGO:0006520610.017
response to oxygen containing compoundGO:19017002000.017
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.017
retina development in camera type eyeGO:006004140.017
protein transportGO:00150311550.016
organophosphate metabolic processGO:00196371950.016
regulation of mitotic sister chromatid separationGO:0010965280.016
cytokinesisGO:0000910900.016
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.016
protein complex biogenesisGO:00702712010.016
vesicle mediated transportGO:00161923810.016
response to temperature stimulusGO:00092661060.016
response to endogenous stimulusGO:00097191190.016
cellular response to heatGO:0034605240.016
regulation of chromosome segregationGO:0051983320.016
cellular macromolecule catabolic processGO:00442651360.016
eye developmentGO:00016543230.015
positive regulation of phosphorus metabolic processGO:00105621390.015
carbohydrate derivative biosynthetic processGO:1901137850.015
organelle assemblyGO:00709251980.015
cellular protein modification processGO:00064644380.015
associative learningGO:0008306650.015
Worm
negative regulation of cell cycleGO:00457861160.015
positive regulation of protein metabolic processGO:00512471280.015
protein catabolic processGO:00301631010.015
response to biotic stimulusGO:00096072940.015
axis specificationGO:00097981670.015
proteolysis involved in cellular protein catabolic processGO:0051603830.015
regulation of proteolysisGO:0030162870.015
regulation of phosphorus metabolic processGO:00511742100.015
multi multicellular organism processGO:00447061230.015
defense response to other organismGO:00985422250.015
regulation of cell deathGO:00109411730.015
negative regulation of chromosome segregationGO:0051985140.015
mapk cascadeGO:00001651070.014
response to external biotic stimulusGO:00432072930.014
organic substance transportGO:00717022570.014
neuromuscular junction developmentGO:00075281490.014
negative regulation of cell divisionGO:0051782170.014
mitotic dna damage checkpointGO:0044773740.014
compound eye morphogenesisGO:00017452490.014
chromosome organizationGO:00512763600.014
protein maturationGO:0051604710.014
regulation of immune system processGO:00026821760.014
wing disc morphogenesisGO:00074723440.014
positive regulation of nitrogen compound metabolic processGO:00511733540.014
rna processingGO:00063961470.014
regulation of cell developmentGO:00602842150.014
respiratory system developmentGO:00605412130.014
imaginal disc derived wing morphogenesisGO:00074763370.014
positive regulation of response to stimulusGO:00485843230.013
mitotic g2 dna damage checkpointGO:0007095690.013
dna metabolic processGO:00062592270.013
regulation of mitosisGO:0007088560.013
protein localizationGO:00081042840.013
response to heatGO:0009408630.013
lipid localizationGO:0010876540.013
synapse organizationGO:00508081960.013
regulation of protein transportGO:0051223570.013
chemosensory behaviorGO:00076351060.013
Worm
ion transportGO:00068111450.013
production of molecular mediator of immune responseGO:0002440460.013
camera type eye developmentGO:004301040.013
positive regulation of cellular biosynthetic processGO:00313283160.013
negative regulation of catabolic processGO:0009895360.013
negative regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032435160.013
blastoderm segmentationGO:00073501590.013
columnar cuboidal epithelial cell differentiationGO:00020652560.013
cellular protein catabolic processGO:0044257830.013
regulation of innate immune responseGO:0045088710.013
kidney epithelium developmentGO:007207330.013
innate immune responseGO:00450871440.013
cellular homeostasisGO:0019725800.012
monocarboxylic acid transportGO:001571830.012
glutathione metabolic processGO:0006749370.012
spindle organizationGO:00070512530.012
catabolic processGO:00090564090.012
positive regulation of intracellular signal transductionGO:19025331160.012
modification dependent protein catabolic processGO:0019941780.012
positive regulation of cell communicationGO:00106472500.012
positive regulation of signal transductionGO:00099672230.012
regulation of organelle organizationGO:00330431960.012
regulation of cellular component biogenesisGO:00440872010.012
nucleoside phosphate metabolic processGO:00067531620.012
regulation of transportGO:00510491810.012
carboxylic acid metabolic processGO:0019752920.012
regulation of phosphorylationGO:00423251470.012
cell fate determinationGO:0001709910.012
positive regulation of macromolecule metabolic processGO:00106044050.012
single organism intracellular transportGO:19025822070.012
cell proliferationGO:00082832990.012
compound eye developmentGO:00487493070.012
positive regulation of cell motilityGO:200014730.012
hematopoietic progenitor cell differentiationGO:000224410.012
locomotory behaviorGO:00076261760.012
positive regulation of immune responseGO:0050778630.012
organic acid metabolic processGO:00060821030.012
response to hexoseGO:000974630.012
negative regulation of nitrogen compound metabolic processGO:00511722650.012
regulation of cellular protein catabolic processGO:1903362440.012
forebrain developmentGO:003090020.012
cellular amine metabolic processGO:0044106120.012
cation transmembrane transportGO:0098655880.011
nephron tubule developmentGO:007208030.011
modification dependent macromolecule catabolic processGO:0043632790.011
immune response regulating signaling pathwayGO:000276420.011
response to extracellular stimulusGO:00099911160.011
eye photoreceptor cell differentiationGO:00017541450.011
response to glucoseGO:000974920.011
compound eye photoreceptor cell differentiationGO:00017511400.011
regulation of multi organism processGO:00439001310.011
segmentationGO:00352822070.011
regulation of mapk cascadeGO:0043408920.011
dna templated transcription initiationGO:0006352250.011
intracellular transportGO:00469072280.011
proteolysisGO:00065081920.011
secondary metabolite catabolic processGO:009048710.011
sensory perception of chemical stimulusGO:00076061160.011
mitotic spindle organizationGO:00070522200.011
proteasomal protein catabolic processGO:0010498590.011
negative regulation of sister chromatid segregationGO:0033046130.011
sensory organ morphogenesisGO:00905962600.011
purine ribonucleotide metabolic processGO:00091501450.011
olfactory behaviorGO:0042048970.011
Worm
negative regulation of multicellular organismal processGO:00512411420.011
Worm
negative regulation of organelle organizationGO:0010639560.011
photoreceptor cell differentiationGO:00465301700.011
spinal cord developmentGO:002151010.011
response to lipopolysaccharideGO:003249640.011
oxidation reduction processGO:00551141230.011
protein processingGO:0016485680.011
positive regulation of programmed cell deathGO:0043068620.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
golgi organizationGO:0007030660.011
germarium derived egg chamber formationGO:00072931010.011
positive regulation of cellular protein metabolic processGO:00322701180.011
positive regulation of rna metabolic processGO:00512542710.011
signal transduction by phosphorylationGO:00230141070.011
membrane organizationGO:00610241120.011
protein heterooligomerizationGO:005129140.011
negative regulation of cellular protein metabolic processGO:0032269850.011
learningGO:0007612750.011
Worm
regulation of nuclear divisionGO:0051783580.011
response to monosaccharideGO:003428440.011
erk1 and erk2 cascadeGO:0070371390.011
chromatin remodelingGO:0006338720.011
multicellular organismal agingGO:00102591400.011
dorsal ventral pattern formationGO:00099531330.011
agingGO:00075681430.011
regulation of transcription from rna polymerase ii promoterGO:00063573780.011
nephron morphogenesisGO:007202830.010
regulation of protein complex assemblyGO:0043254420.010
phagocytosisGO:00069092150.010
secretion by cellGO:00329401010.010
centrosome duplicationGO:00512981210.010
carbohydrate metabolic processGO:0005975820.010
appendage morphogenesisGO:00351073970.010
organophosphate catabolic processGO:00464341120.010
negative regulation of epithelial cell proliferationGO:005068040.010
regulation of multicellular organismal developmentGO:20000264140.010
Worm
cell junction organizationGO:0034330570.010
carbohydrate derivative metabolic processGO:19011352170.010
reproductive system developmentGO:0061458740.010
Worm
negative regulation of proteasomal protein catabolic processGO:1901799160.010
endomembrane system organizationGO:00102561190.010

HP1e disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.028
musculoskeletal system diseaseDOID:1700.014
nervous system diseaseDOID:86300.012
hypertensionDOID:1076300.010
vascular diseaseDOID:17800.010
cardiovascular system diseaseDOID:128700.010
essential hypertensionDOID:1082500.010
artery diseaseDOID:005082800.010