IMP: Integrative Multi-species Prediction

Drosophila melanogaster

175 known processes

DopEcR (Dmel_CG18314)

CG18314 gene product from transcript CG18314-RB

(Aliases: CG18314,DmDopEcR,anon-WO0170980.140,anon-WO0170980.139,Dmel\CG18314)

Entrez: 38539
FLYBASE: FBgn0035538
UniProtKB: Q9VZD1

Process Predictions
Disease Predictions

DopEcR biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability
learning or memory	GO:0007611	141	0.848
neurological system process	GO:0050877	358	0.606
memory	GO:0007613	94	0.536
cognition	GO:0050890	141	0.493
male courtship behavior	GO:0008049	63	0.246
eye development	GO:0001654	323	0.246
eye morphogenesis	GO:0048592	260	0.177
learning	GO:0007612	75	0.156
multi organism reproductive behavior	GO:0044705	121	0.156
multi organism behavior	GO:0051705	175	0.139
courtship behavior	GO:0007619	68	0.137
reproductive behavior	GO:0019098	122	0.133
mating	GO:0007618	120	0.133
compound eye development	GO:0048749	307	0.126
behavioral response to ethanol	GO:0048149	49	0.124
synapse assembly	GO:0007416	143	0.124
mating behavior	GO:0007617	106	0.123
single organism behavior	GO:0044708	391	0.107
neuromuscular junction development	GO:0007528	149	0.106
taxis	GO:0042330	304	0.102
sensory organ morphogenesis	GO:0090596	260	0.100
multi multicellular organism process	GO:0044706	123	0.099
regulation of cellular component biogenesis	GO:0044087	201	0.097
locomotory behavior	GO:0007626	176	0.091
regulation of synaptic growth at neuromuscular junction	GO:0008582	89	0.089
response to ethanol	GO:0045471	59	0.089
sensory perception	GO:0007600	196	0.087
synaptic growth at neuromuscular junction	GO:0051124	119	0.087
synaptic transmission	GO:0007268	288	0.086
multicellular organismal reproductive behavior	GO:0033057	110	0.084
intracellular transport	GO:0046907	228	0.081
cell projection assembly	GO:0030031	94	0.076
developmental growth	GO:0048589	280	0.076
cellular response to chemical stimulus	GO:0070887	199	0.071
growth	GO:0040007	359	0.069
response to radiation	GO:0009314	155	0.066
regulation of circadian sleep wake cycle sleep	GO:0045187	21	0.065
sleep	GO:0030431	49	0.065
regulation of synapse assembly	GO:0051963	94	0.059
anatomical structure homeostasis	GO:0060249	97	0.058
negative regulation of cellular metabolic process	GO:0031324	382	0.055
circadian behavior	GO:0048512	76	0.052
eye photoreceptor cell differentiation	GO:0001754	145	0.052
cellular ketone metabolic process	GO:0042180	24	0.052
neuron recognition	GO:0008038	101	0.051
synapse organization	GO:0050808	196	0.049
rhythmic process	GO:0048511	106	0.048
phosphorylation	GO:0016310	294	0.047
regulation of growth	GO:0040008	233	0.046
negative regulation of developmental process	GO:0051093	201	0.046
regulation of multicellular organismal development	GO:2000026	414	0.044
associative learning	GO:0008306	65	0.042
protein complex assembly	GO:0006461	200	0.042
adult locomotory behavior	GO:0008344	76	0.042
organonitrogen compound metabolic process	GO:1901564	318	0.042
regionalization	GO:0003002	416	0.041
negative regulation of response to stimulus	GO:0048585	258	0.041
response to organic substance	GO:0010033	284	0.040
spermatid differentiation	GO:0048515	114	0.040
protein modification process	GO:0036211	438	0.039
response to abiotic stimulus	GO:0009628	341	0.039
macromolecular complex assembly	GO:0065003	256	0.039
detection of light stimulus	GO:0009583	58	0.039
cellular macromolecule localization	GO:0070727	220	0.037
protein localization	GO:0008104	284	0.037
regulation of nervous system development	GO:0051960	248	0.037
negative regulation of cell communication	GO:0010648	223	0.036
forebrain development	GO:0030900	2	0.035
sensory perception of sound	GO:0007605	56	0.034
neuron projection guidance	GO:0097485	241	0.034
response to oxygen containing compound	GO:1901700	200	0.033
small molecule metabolic process	GO:0044281	305	0.033
ovarian follicle cell development	GO:0030707	248	0.033
circadian rhythm	GO:0007623	105	0.032
carboxylic acid metabolic process	GO:0019752	92	0.032
response to bacterium	GO:0009617	198	0.032
regulation of cell death	GO:0010941	173	0.032
protein complex biogenesis	GO:0070271	201	0.032
regulation of intracellular signal transduction	GO:1902531	236	0.031
intracellular signal transduction	GO:0035556	300	0.031
response to lipopolysaccharide	GO:0032496	4	0.031
regulation of localization	GO:0032879	275	0.030
ras protein signal transduction	GO:0007265	88	0.030
endocytosis	GO:0006897	310	0.030
positive regulation of molecular function	GO:0044093	136	0.030
flight behavior	GO:0007629	26	0.030
response to external biotic stimulus	GO:0043207	293	0.030
compound eye morphogenesis	GO:0001745	249	0.030
response to biotic stimulus	GO:0009607	294	0.030
telencephalon development	GO:0021537	2	0.029
small gtpase mediated signal transduction	GO:0007264	88	0.029
single organism biosynthetic process	GO:0044711	206	0.029
transmembrane transport	GO:0055085	139	0.029
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.029
chemosensory behavior	GO:0007635	106	0.029
establishment of localization in cell	GO:0051649	402	0.029
positive regulation of multicellular organismal process	GO:0051240	143	0.029
cellular response to endogenous stimulus	GO:0071495	80	0.029
regulation of catalytic activity	GO:0050790	185	0.028
cellular response to molecule of bacterial origin	GO:0071219	3	0.028
neurotransmitter metabolic process	GO:0042133	2	0.028
exocrine system development	GO:0035272	162	0.028
organic substance transport	GO:0071702	257	0.028
endomembrane system organization	GO:0010256	119	0.028
vesicle mediated transport	GO:0016192	381	0.027
cellular catabolic process	GO:0044248	372	0.027
response to other organism	GO:0051707	293	0.027
cellular amino acid metabolic process	GO:0006520	61	0.027
actin filament based process	GO:0030029	220	0.027
multicellular organismal aging	GO:0010259	140	0.027
negative regulation of rna biosynthetic process	GO:1902679	240	0.027
regulation of protein modification process	GO:0031399	112	0.026
cellular protein modification process	GO:0006464	438	0.026
larval behavior	GO:0030537	42	0.026
organic acid metabolic process	GO:0006082	103	0.026
localization of cell	GO:0051674	257	0.026
regulation of cellular localization	GO:0060341	136	0.026
organelle assembly	GO:0070925	198	0.026
rhabdomere development	GO:0042052	38	0.026
organic substance catabolic process	GO:1901575	308	0.026
biological adhesion	GO:0022610	138	0.025
regulation of protein metabolic process	GO:0051246	256	0.025
olfactory behavior	GO:0042048	97	0.025
nucleoside phosphate metabolic process	GO:0006753	162	0.025
oxoacid metabolic process	GO:0043436	103	0.025
regulation of synapse organization	GO:0050807	110	0.025
axon guidance	GO:0007411	233	0.025
divalent metal ion transport	GO:0070838	26	0.025
stem cell differentiation	GO:0048863	117	0.024
nucleobase containing small molecule metabolic process	GO:0055086	174	0.024
cell recognition	GO:0008037	102	0.024
purine nucleotide metabolic process	GO:0006163	146	0.024
regulation of olfactory learning	GO:0090328	8	0.024
cellular homeostasis	GO:0019725	80	0.024
phototransduction	GO:0007602	52	0.024
central nervous system development	GO:0007417	201	0.024
axonogenesis	GO:0007409	290	0.024
regulation of cellular amine metabolic process	GO:0033238	3	0.024
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.023
lateral inhibition	GO:0046331	206	0.023
olfactory learning	GO:0008355	56	0.023
cell junction organization	GO:0034330	57	0.023
regulation of transport	GO:0051049	181	0.023
regulation of developmental growth	GO:0048638	174	0.023
synaptic target recognition	GO:0008039	45	0.022
ameboidal type cell migration	GO:0001667	151	0.022
g protein coupled receptor signaling pathway	GO:0007186	136	0.022
photoreceptor cell development	GO:0042461	96	0.022
regulation of ras protein signal transduction	GO:0046578	93	0.022
sensory perception of mechanical stimulus	GO:0050954	72	0.022
cell maturation	GO:0048469	144	0.022
regulation of synaptic transmission	GO:0050804	69	0.021
negative regulation of protein metabolic process	GO:0051248	85	0.021
adult behavior	GO:0030534	137	0.021
cellular protein localization	GO:0034613	160	0.021
acetylcholine metabolic process	GO:0008291	2	0.021
regulation of cell proliferation	GO:0042127	163	0.021
chemotaxis	GO:0006935	249	0.021
long term memory	GO:0007616	62	0.021
rhythmic behavior	GO:0007622	76	0.021
response to glucose	GO:0009749	2	0.020
digestive system development	GO:0055123	149	0.020
microtubule polymerization or depolymerization	GO:0031109	39	0.020
cell cycle phase transition	GO:0044770	140	0.020
body morphogenesis	GO:0010171	2	0.020
sensory perception of chemical stimulus	GO:0007606	116	0.020
regulation of tube size	GO:0035150	46	0.020
amine metabolic process	GO:0009308	12	0.020
aggressive behavior	GO:0002118	63	0.020
catabolic process	GO:0009056	409	0.020
photoreceptor cell differentiation	GO:0046530	170	0.020
cellular nitrogen compound catabolic process	GO:0044270	165	0.019
cell death	GO:0008219	279	0.019
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.019
regulation of organelle organization	GO:0033043	196	0.019
purine nucleoside catabolic process	GO:0006152	112	0.019
positive regulation of cellular component organization	GO:0051130	156	0.019
regulation of nucleotide catabolic process	GO:0030811	48	0.019
phagocytosis	GO:0006909	215	0.019
inorganic cation transmembrane transport	GO:0098662	61	0.019
gtp catabolic process	GO:0006184	72	0.019
positive regulation of biosynthetic process	GO:0009891	316	0.019
response to alcohol	GO:0097305	95	0.018
response to hexose	GO:0009746	3	0.018
regulation of erbb signaling pathway	GO:1901184	42	0.018
protein phosphorylation	GO:0006468	169	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.018
cell adhesion	GO:0007155	136	0.018
cellular component assembly involved in morphogenesis	GO:0010927	151	0.018
regulation of ion transport	GO:0043269	39	0.018
actin cytoskeleton organization	GO:0030036	206	0.018
positive regulation of response to stimulus	GO:0048584	323	0.017
pattern recognition receptor signaling pathway	GO:0002221	2	0.017
motor neuron axon guidance	GO:0008045	58	0.017
negative regulation of signaling	GO:0023057	219	0.017
regulation of cell cycle	GO:0051726	291	0.017
heterocycle catabolic process	GO:0046700	166	0.017
acetate ester metabolic process	GO:1900619	2	0.017
compound eye photoreceptor development	GO:0042051	78	0.017
negative regulation of cellular biosynthetic process	GO:0031327	277	0.017
organic cyclic compound catabolic process	GO:1901361	168	0.017
ion transport	GO:0006811	145	0.017
cell migration	GO:0016477	238	0.017
regulation of cellular ketone metabolic process	GO:0010565	3	0.017
tissue migration	GO:0090130	155	0.017
ion transmembrane transport	GO:0034220	122	0.017
regulation of anatomical structure size	GO:0090066	163	0.017
regulation of proteolysis	GO:0030162	87	0.016
cytoplasmic transport	GO:0016482	130	0.016
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.016
inter male aggressive behavior	GO:0002121	60	0.016
lipid metabolic process	GO:0006629	121	0.016
regulation of cytoskeleton organization	GO:0051493	89	0.016
positive regulation of cytoskeleton organization	GO:0051495	21	0.016
cation transmembrane transport	GO:0098655	88	0.016
camera type eye development	GO:0043010	4	0.016
negative regulation of multicellular organismal process	GO:0051241	142	0.016
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.016
cell proliferation	GO:0008283	299	0.016
purine containing compound metabolic process	GO:0072521	155	0.016
chemical homeostasis	GO:0048878	92	0.016
response to wounding	GO:0009611	94	0.016
camera type eye morphogenesis	GO:0048593	2	0.015
ribose phosphate metabolic process	GO:0019693	145	0.015
regulation of synapse structure and activity	GO:0050803	128	0.015
mitotic cell cycle phase transition	GO:0044772	138	0.015
cellular amine metabolic process	GO:0044106	12	0.015
nucleotide metabolic process	GO:0009117	161	0.015
regulation of cellular amino acid metabolic process	GO:0006521	0	0.015
immune response activating signal transduction	GO:0002757	2	0.015
regulation of phosphorylation	GO:0042325	147	0.015
regulation of locomotion	GO:0040012	42	0.015
regulation of cellular protein metabolic process	GO:0032268	243	0.015
cell motility	GO:0048870	251	0.015
single organism intracellular transport	GO:1902582	207	0.015
morphogenesis of an epithelium	GO:0002009	276	0.015
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.015
ovarian follicle cell migration	GO:0007297	121	0.015
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.015
terminal button organization	GO:0072553	19	0.015
regulation of cell cycle phase transition	GO:1901987	130	0.015
cellular response to biotic stimulus	GO:0071216	4	0.015
molting cycle chitin based cuticle	GO:0007591	56	0.015
metal ion transport	GO:0030001	74	0.014
cell cell junction organization	GO:0045216	55	0.014
positive regulation of phosphate metabolic process	GO:0045937	139	0.014
carbohydrate derivative catabolic process	GO:1901136	118	0.014
convergent extension	GO:0060026	2	0.014
positive regulation of signaling	GO:0023056	243	0.014
determination of adult lifespan	GO:0008340	137	0.014
regulation of catabolic process	GO:0009894	170	0.014
regulation of defense response	GO:0031347	102	0.014
protein transport	GO:0015031	155	0.014
establishment of protein localization	GO:0045184	163	0.014
intracellular protein transport	GO:0006886	104	0.014
cellular protein complex assembly	GO:0043623	71	0.014
ribonucleoside metabolic process	GO:0009119	127	0.014
regulation of nucleoside metabolic process	GO:0009118	50	0.014
organonitrogen compound catabolic process	GO:1901565	128	0.014
regulation of cell cycle process	GO:0010564	181	0.014
plasma membrane organization	GO:0007009	26	0.014
negative regulation of phosphorus metabolic process	GO:0010563	45	0.014
organophosphate catabolic process	GO:0046434	112	0.014
regulation of mitotic cell cycle	GO:0007346	190	0.014
entrainment of circadian clock	GO:0009649	16	0.014
intraspecies interaction between organisms	GO:0051703	4	0.014
organophosphate metabolic process	GO:0019637	195	0.014
visual learning	GO:0008542	4	0.014
negative regulation of cellular component organization	GO:0051129	108	0.014
circulatory system process	GO:0003013	37	0.014
gtp metabolic process	GO:0046039	72	0.013
regulation of phosphate metabolic process	GO:0019220	210	0.013
segmentation	GO:0035282	207	0.013
embryonic pattern specification	GO:0009880	174	0.013
muscle system process	GO:0003012	21	0.013
negative regulation of synapse assembly	GO:0051964	39	0.013
nitrogen compound transport	GO:0071705	85	0.013
neuromuscular synaptic transmission	GO:0007274	67	0.013
carbohydrate derivative metabolic process	GO:1901135	217	0.013
epithelial cell differentiation	GO:0030855	322	0.013
regulation of molecular function	GO:0065009	217	0.013
axon development	GO:0061564	297	0.013
cellular response to lipopolysaccharide	GO:0071222	3	0.013
lipopolysaccharide mediated signaling pathway	GO:0031663	1	0.013
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.013
imaginal disc derived wing morphogenesis	GO:0007476	337	0.013
defense response	GO:0006952	300	0.013
nucleoside triphosphate catabolic process	GO:0009143	108	0.013
negative regulation of immune system process	GO:0002683	50	0.013
wing disc morphogenesis	GO:0007472	344	0.013
adherens junction organization	GO:0034332	27	0.013
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.013
regulation of programmed cell death	GO:0043067	152	0.012
cation transport	GO:0006812	110	0.012
regulation of microtubule polymerization or depolymerization	GO:0031110	27	0.012
ribonucleoside catabolic process	GO:0042454	112	0.012
negative regulation of erk1 and erk2 cascade	GO:0070373	3	0.012
aromatic compound catabolic process	GO:0019439	166	0.012
axis specification	GO:0009798	167	0.012
forward locomotion	GO:0043056	1	0.012
heart development	GO:0007507	82	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
regulation of epithelial cell differentiation	GO:0030856	4	0.012
positive regulation of cell communication	GO:0010647	250	0.012
positive regulation of nucleotide metabolic process	GO:0045981	55	0.012
positive regulation of adenylate cyclase activity involved in g protein coupled receptor signaling pathway	GO:0010579	7	0.012
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.012
negative regulation of erbb signaling pathway	GO:1901185	29	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
bmp signaling pathway	GO:0030509	27	0.012
post embryonic appendage morphogenesis	GO:0035120	385	0.012
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.012
nucleoside phosphate catabolic process	GO:1901292	110	0.012
gland development	GO:0048732	191	0.012
negative regulation of phosphorylation	GO:0042326	35	0.012
digestive tract development	GO:0048565	149	0.012
developmental programmed cell death	GO:0010623	138	0.012
response to decreased oxygen levels	GO:0036293	58	0.012
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.012
notch signaling pathway	GO:0007219	120	0.012
positive regulation of cellular component biogenesis	GO:0044089	80	0.012
inorganic ion transmembrane transport	GO:0098660	73	0.012
tube morphogenesis	GO:0035239	191	0.012
nucleobase containing compound catabolic process	GO:0034655	165	0.012
immune response	GO:0006955	246	0.012
anesthesia resistant memory	GO:0007615	6	0.011
nucleoside triphosphate metabolic process	GO:0009141	120	0.011
male gamete generation	GO:0048232	201	0.011
cellular response to organic substance	GO:0071310	132	0.011
cell junction assembly	GO:0034329	42	0.011
positive regulation of catalytic activity	GO:0043085	118	0.011
salivary gland development	GO:0007431	162	0.011
negative regulation of signal transduction	GO:0009968	206	0.011
carbohydrate derivative biosynthetic process	GO:1901137	85	0.011
hindbrain development	GO:0030902	2	0.011
programmed cell death	GO:0012501	257	0.011
response to organophosphorus	GO:0046683	2	0.011
regulation of purine nucleotide catabolic process	GO:0033121	48	0.011
negative regulation of rna metabolic process	GO:0051253	251	0.011
negative regulation of epithelial cell proliferation	GO:0050680	4	0.011
anterior posterior pattern specification	GO:0009952	136	0.011
mapk cascade	GO:0000165	107	0.011
defense response to gram negative bacterium	GO:0050829	94	0.011
single organism membrane organization	GO:0044802	93	0.011
positive regulation of phosphorus metabolic process	GO:0010562	139	0.011
regulation of cell matrix adhesion	GO:0001952	1	0.011
cellular response to decreased oxygen levels	GO:0036294	30	0.011
reactive oxygen species metabolic process	GO:0072593	22	0.011
gland morphogenesis	GO:0022612	145	0.011
eye photoreceptor cell development	GO:0042462	81	0.011
cellular response to carbohydrate stimulus	GO:0071322	4	0.011
response to oxidative stress	GO:0006979	86	0.011
negative regulation of phosphate metabolic process	GO:0045936	45	0.011
regulation of actin cytoskeleton organization	GO:0032956	42	0.011
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.011
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.011
epithelial cell development	GO:0002064	274	0.011
negative regulation of immune response	GO:0050777	39	0.011
response to temperature stimulus	GO:0009266	106	0.011
regulation of circadian rhythm	GO:0042752	49	0.011
regulation of cell substrate adhesion	GO:0010810	2	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
cellular response to oxygen containing compound	GO:1901701	79	0.010
kidney development	GO:0001822	3	0.010
positive regulation of cell migration	GO:0030335	2	0.010
spermatogenesis	GO:0007283	200	0.010
single organism catabolic process	GO:0044712	228	0.010
glycosyl compound metabolic process	GO:1901657	127	0.010
cellular macromolecular complex assembly	GO:0034622	153	0.010
epithelial cell migration	GO:0010631	148	0.010
purine nucleoside metabolic process	GO:0042278	127	0.010
brain development	GO:0007420	120	0.010
regulation of transmembrane transport	GO:0034762	27	0.010
purine ribonucleoside metabolic process	GO:0046128	127	0.010
positive regulation of gene expression	GO:0010628	290	0.010
negative regulation of synaptic growth at neuromuscular junction	GO:0045886	39	0.010
short term memory	GO:0007614	19	0.010
regulation of kinase activity	GO:0043549	53	0.010
response to endogenous stimulus	GO:0009719	119	0.010

DopEcR disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.033
nervous system disease	DOID:863	0.025
cardiovascular system disease	DOID:1287	0.015
central nervous system disease	DOID:331	0.011

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