IMP: Integrative Multi-species Prediction

Drosophila melanogaster

25 known processes

RpL13 (Dmel_CG4651)

Ribosomal protein L13

(Aliases: CG4651,rpL13,Dmel\CG4651,Rpl13,L13,anon-EST:fe1D1,bbc1,M(2)31A,Dmbbc1,Bbc1)

Entrez: 34329
FLYBASE: FBgn0011272
UniProtKB: P41126
UniProtKB: M9PFF0

Process Predictions
Disease Predictions

RpL13 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
spindle elongation	GO:0051231	83	0.794
centrosome duplication	GO:0051298	121	0.707
mitotic spindle elongation	GO:0000022	81	0.572
larval development	GO:0002164	104	0.454	Worm
embryo development ending in birth or egg hatching	GO:0009792	152	0.435	Worm
death	GO:0016265	284	0.279	Worm
programmed cell death	GO:0012501	257	0.272	Worm
mitotic spindle organization	GO:0007052	220	0.265
multicellular organismal aging	GO:0010259	140	0.262
rrna processing	GO:0006364	3	0.230
cell death	GO:0008219	279	0.220	Worm
cytoplasmic translation	GO:0002181	0	0.215
dna metabolic process	GO:0006259	227	0.186
regulation of cell cycle	GO:0051726	291	0.155	Zebrafish
centrosome cycle	GO:0007098	137	0.143
determination of adult lifespan	GO:0008340	137	0.139
spindle organization	GO:0007051	253	0.131
apoptotic process	GO:0006915	159	0.125	Worm
ribosomal large subunit biogenesis	GO:0042273	1	0.118
establishment of localization in cell	GO:0051649	402	0.117
meiotic cell cycle	GO:0051321	171	0.099
nuclear division	GO:0000280	332	0.086
positive regulation of multicellular organismal process	GO:0051240	143	0.081
aging	GO:0007568	143	0.075
immune system process	GO:0002376	347	0.073
negative regulation of gene expression	GO:0010629	387	0.061
regulation of developmental growth	GO:0048638	174	0.060
nucleosome assembly	GO:0006334	35	0.057
organelle assembly	GO:0070925	198	0.055
vesicle mediated transport	GO:0016192	381	0.054
cellular protein modification process	GO:0006464	438	0.052
molting cycle	GO:0042303	56	0.052
sex differentiation	GO:0007548	81	0.051
meiotic nuclear division	GO:0007126	151	0.048
cellular macromolecular complex assembly	GO:0034622	153	0.048
macromolecular complex assembly	GO:0065003	256	0.048
reproductive system development	GO:0061458	74	0.047
development of primary sexual characteristics	GO:0045137	50	0.047
centrosome organization	GO:0051297	163	0.047
ribonucleoprotein complex assembly	GO:0022618	23	0.047
body morphogenesis	GO:0010171	2	0.045
meiotic cell cycle process	GO:1903046	132	0.043
regulation of intracellular signal transduction	GO:1902531	236	0.042
endocytosis	GO:0006897	310	0.041
ribonucleoprotein complex subunit organization	GO:0071826	28	0.039
exocrine system development	GO:0035272	162	0.037
gland development	GO:0048732	191	0.035
positive regulation of biosynthetic process	GO:0009891	316	0.034
cell proliferation	GO:0008283	299	0.034
gonad development	GO:0008406	50	0.034
developmental growth	GO:0048589	280	0.032
reproductive structure development	GO:0048608	74	0.031
salivary gland development	GO:0007431	162	0.030
tissue morphogenesis	GO:0048729	297	0.029
negative regulation of biosynthetic process	GO:0009890	277	0.028
regulation of growth	GO:0040008	233	0.027
microtubule organizing center organization	GO:0031023	168	0.027
ribonucleoprotein complex biogenesis	GO:0022613	31	0.026
organic substance transport	GO:0071702	257	0.026
regulation of cell death	GO:0010941	173	0.026
salivary gland morphogenesis	GO:0007435	145	0.025
cytoplasmic transport	GO:0016482	130	0.025
establishment or maintenance of cell polarity	GO:0007163	167	0.025
organelle fission	GO:0048285	340	0.025
phosphorylation	GO:0016310	294	0.024
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.024
cell migration	GO:0016477	238	0.023
positive regulation of macromolecule metabolic process	GO:0010604	405	0.022
salivary gland cell autophagic cell death	GO:0035071	83	0.022
single organism intracellular transport	GO:1902582	207	0.022
positive regulation of developmental process	GO:0051094	143	0.021
translation	GO:0006412	69	0.021
multi organism behavior	GO:0051705	175	0.021
immune system development	GO:0002520	57	0.021
positive regulation of cellular biosynthetic process	GO:0031328	316	0.020
regulation of apoptotic process	GO:0042981	130	0.020
posttranscriptional regulation of gene expression	GO:0010608	145	0.020
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.020
regulation of multicellular organismal development	GO:2000026	414	0.019
tube morphogenesis	GO:0035239	191	0.018
ncrna processing	GO:0034470	30	0.017
response to external biotic stimulus	GO:0043207	293	0.017
cell motility	GO:0048870	251	0.017
negative regulation of signal transduction	GO:0009968	206	0.017
negative regulation of signaling	GO:0023057	219	0.017
gland morphogenesis	GO:0022612	145	0.016
rna processing	GO:0006396	147	0.016
regulation of molecular function	GO:0065009	217	0.016
positive regulation of catalytic activity	GO:0043085	118	0.016
genitalia development	GO:0048806	26	0.016
autophagic cell death	GO:0048102	83	0.016
protein modification process	GO:0036211	438	0.016
cellular response to dna damage stimulus	GO:0006974	223	0.015
growth	GO:0040007	359	0.015
positive regulation of molecular function	GO:0044093	136	0.015
intracellular transport	GO:0046907	228	0.015
receptor mediated endocytosis	GO:0006898	21	0.015
axon development	GO:0061564	297	0.015
regulation of mapk cascade	GO:0043408	92	0.015
regulation of phosphorus metabolic process	GO:0051174	210	0.015
ribosome biogenesis	GO:0042254	8	0.014
positive regulation of cell communication	GO:0010647	250	0.014
multicellular organism growth	GO:0035264	46	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
developmental programmed cell death	GO:0010623	138	0.014
reproductive behavior	GO:0019098	122	0.014
notch signaling pathway	GO:0007219	120	0.014
cell recognition	GO:0008037	102	0.014
regulation of localization	GO:0032879	275	0.013
salivary gland histolysis	GO:0035070	88	0.013
positive regulation of signaling	GO:0023056	243	0.013
cellular response to chemical stimulus	GO:0070887	199	0.013
positive regulation of gene expression	GO:0010628	290	0.013
protein complex biogenesis	GO:0070271	201	0.013
positive regulation of protein metabolic process	GO:0051247	128	0.013
multicellular organismal reproductive behavior	GO:0033057	110	0.013
intracellular signal transduction	GO:0035556	300	0.012
neuron projection guidance	GO:0097485	241	0.012
establishment of organelle localization	GO:0051656	122	0.012
localization of cell	GO:0051674	257	0.012
protein transport	GO:0015031	155	0.012
regulation of multicellular organism growth	GO:0040014	40	0.012
cellular response to organic substance	GO:0071310	132	0.011
regulation of cellular component biogenesis	GO:0044087	201	0.011
histolysis	GO:0007559	102	0.011
muscle tissue development	GO:0060537	30	0.011
negative regulation of rna metabolic process	GO:0051253	251	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
regulation of mitotic cell cycle	GO:0007346	190	0.011
proteolysis	GO:0006508	192	0.010
peptidyl proline modification	GO:0018208	3	0.010
positive regulation of viral process	GO:0048524	2	0.010
positive regulation of developmental growth	GO:0048639	62	0.010
amine metabolic process	GO:0009308	12	0.010
signal transduction by phosphorylation	GO:0023014	107	0.010

RpL13 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.155
hematopoietic system disease	DOID:74	0.022
immune system disease	DOID:2914	0.022
anemia	DOID:2355	0.022
bone marrow disease	DOID:4961	0.021
aplastic anemia	DOID:12449	0.021
congenital hypoplastic anemia	DOID:1342	0.016

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