Drosophila melanogaster

65 known processes

mre11 (Dmel_CG16928)

meiotic recombination 11

(Aliases: Dmel\CG16928,MRE11,16928,Mre11,CG16928)

mre11 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cellular response to dna damage stimulusGO:00069742230.976
dna damage checkpointGO:0000077780.970
telomere cappingGO:0016233110.911
double strand break repairGO:0006302260.775
Yeast Mouse
mitotic dna damage checkpointGO:0044773740.772
dna replicationGO:0006260480.645
Human
telomere maintenanceGO:0000723210.616
telomere organizationGO:0032200210.597
recombinational repairGO:0000725130.525
Yeast
regulation of cell cycle phase transitionGO:19019871300.489
dna recombinationGO:0006310320.473
Yeast
negative regulation of cell cycle processGO:00109481090.451
dna geometric changeGO:0032392160.440
Human
axon developmentGO:00615642970.429
mitotic dna integrity checkpointGO:0044774750.426
response to light stimulusGO:00094161240.422
homeostatic processGO:00425921990.339
regulation of cell cycle processGO:00105641810.310
negative regulation of cell cycleGO:00457861160.301
cell cycle checkpointGO:0000075950.300
dna metabolic processGO:00062592270.273
negative regulation of cellular metabolic processGO:00313243820.265
Human
regulation of dna recombinationGO:000001840.246
dna repairGO:0006281540.246
Yeast Mouse
dna double strand break processingGO:000072930.221
Yeast
negative regulation of cell cycle phase transitionGO:19019881030.214
dna integrity checkpointGO:0031570810.206
anatomical structure homeostasisGO:0060249970.200
mitotic g2 dna damage checkpointGO:0007095690.198
regulation of mitotic cell cycleGO:00073461900.194
dna duplex unwindingGO:0032508160.182
Human
chromosome organizationGO:00512763600.166
response to radiationGO:00093141550.153
regulation of dna metabolic processGO:0051052340.142
Human
mrna metabolic processGO:00160711240.123
positive regulation of intracellular signal transductionGO:19025331160.121
positive regulation of phosphorus metabolic processGO:00105621390.111
Human
regulation of cell cycleGO:00517262910.111
double strand break repair via homologous recombinationGO:0000724130.106
Yeast
nucleoside phosphate catabolic processGO:19012921100.098
Human
negative regulation of cellular biosynthetic processGO:00313272770.097
Human
g2 dna damage checkpointGO:0031572690.091
organelle fissionGO:00482853400.089
Yeast Mouse Worm
small molecule metabolic processGO:00442813050.087
Human Yeast
mitotic recombinationGO:000631220.080
negative regulation of mitotic cell cycle phase transitionGO:19019911030.078
mitotic cell cycle phase transitionGO:00447721380.071
postreplication repairGO:000630120.071
cellular response to chemical stimulusGO:00708871990.069
nucleotide excision repairGO:000628980.066
positive regulation of catalytic activityGO:00430851180.064
Human
response to abiotic stimulusGO:00096283410.063
positive regulation of signalingGO:00230562430.062
regulation of mitotic cell cycle phase transitionGO:19019901300.062
regulation of catalytic activityGO:00507901850.061
Human
mitotic g2 m transition checkpointGO:0044818700.060
deathGO:00162652840.059
single organism biosynthetic processGO:00447112060.058
Human
embryo development ending in birth or egg hatchingGO:00097921520.056
Worm
immune system processGO:00023763470.053
regulation of phosphate metabolic processGO:00192202100.053
Human
dna conformation changeGO:00711031050.052
Human
cell cycle phase transitionGO:00447701400.051
positive regulation of response to stimulusGO:00485843230.049
regulation of gene expression epigeneticGO:00400291280.048
mitotic nuclear divisionGO:00070672130.048
cell deathGO:00082192790.047
cell agingGO:000756920.046
negative regulation of nucleobase containing compound metabolic processGO:00459342610.044
Human
positive regulation of cell communicationGO:00106472500.043
regulation of meiosisGO:004002030.042
intrinsic apoptotic signaling pathway in response to dna damageGO:0008630110.042
meiotic cell cycleGO:00513211710.041
Yeast Mouse Worm
ribonucleotide metabolic processGO:00092591450.040
Human
nucleobase containing compound catabolic processGO:00346551650.039
Human Yeast
mitotic cell cycle checkpointGO:0007093880.039
cell cell signaling involved in cell fate commitmentGO:00451682100.039
dna dependent dna replicationGO:0006261170.038
Human
positive regulation of phosphate metabolic processGO:00459371390.038
Human
regulation of cellular response to stressGO:0080135890.038
regulation of phosphorus metabolic processGO:00511742100.038
Human
telomere maintenance via recombinationGO:000072210.038
meiotic chromosome segregationGO:0045132590.038
Worm
nucleobase containing small molecule metabolic processGO:00550861740.038
Human Yeast
biological adhesionGO:00226101380.037
gene silencingGO:00164581380.037
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.036
aromatic compound catabolic processGO:00194391660.035
Human Yeast
negative regulation of rna metabolic processGO:00512532510.035
regulation of protein metabolic processGO:00512462560.035
Human
regulation of cellular amine metabolic processGO:003323830.033
organophosphate metabolic processGO:00196371950.033
Human Yeast
meiotic nuclear divisionGO:00071261510.031
Yeast Mouse Worm
translesion synthesisGO:001998520.029
ribose phosphate metabolic processGO:00196931450.029
Human
purine nucleoside monophosphate metabolic processGO:0009126500.029
Human
vesicle mediated transportGO:00161923810.029
intracellular signal transductionGO:00355563000.028
cell divisionGO:00513012480.028
epithelial cell developmentGO:00020642740.027
dna biosynthetic processGO:0071897240.026
heterocycle catabolic processGO:00467001660.026
Human Yeast
programmed cell deathGO:00125012570.026
response to ionizing radiationGO:0010212320.025
nuclear divisionGO:00002803320.025
Yeast Mouse Worm
purine ribonucleotide metabolic processGO:00091501450.025
Human
ribonucleoside triphosphate metabolic processGO:00091991190.025
Human
positive regulation of signal transductionGO:00099672230.025
positive regulation of phosphorylationGO:0042327870.024
Human
chromosome condensationGO:0030261410.024
respiratory system developmentGO:00605412130.024
protein modification processGO:00362114380.024
Human
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.024
Human
cell cycle g1 s phase transitionGO:0044843310.024
ribonucleoside triphosphate catabolic processGO:00092031080.024
Human
response to organic substanceGO:00100332840.023
negative regulation of nitrogen compound metabolic processGO:00511722650.023
Human
signal transduction by phosphorylationGO:00230141070.023
nucleotide metabolic processGO:00091171610.022
Human Yeast
signal transduction in response to dna damageGO:004277030.021
response to uvGO:0009411240.021
regulation of mapk cascadeGO:0043408920.021
axonogenesisGO:00074092900.021
negative regulation of mitotic cell cycleGO:00459301090.021
regulation of cell deathGO:00109411730.021
positive regulation of proteolysisGO:0045862520.021
cellular response to radiationGO:0071478520.020
double strand break repair via synthesis dependent strand annealingGO:004500360.020
Yeast
positive regulation of purine nucleotide metabolic processGO:1900544550.020
nuclear dna replicationGO:003326010.020
cellular response to organic substanceGO:00713101320.020
regulation of cell divisionGO:0051302720.019
regulation of nucleotide metabolic processGO:0006140620.019
immune responseGO:00069552460.019
negative regulation of gene expression epigeneticGO:0045814770.019
organonitrogen compound metabolic processGO:19015643180.019
Human
cellular nitrogen compound catabolic processGO:00442701650.019
Human Yeast
chromatin silencingGO:0006342760.019
chromosome segregationGO:00070591570.018
Human Worm
regulation of response to dna damage stimulusGO:2001020230.018
rna localizationGO:00064031150.018
regulation of cellular ketone metabolic processGO:001056530.018
ribonucleoside metabolic processGO:00091191270.018
Human
regulation of cell proliferationGO:00421271630.018
organic cyclic compound catabolic processGO:19013611680.017
Human Yeast
regulation of intracellular transportGO:0032386640.017
sex differentiationGO:0007548810.017
positive regulation of hydrolase activityGO:0051345780.017
response to fungusGO:0009620500.017
negative regulation of response to stimulusGO:00485852580.017
purine ribonucleotide catabolic processGO:00091541090.017
Human
purine nucleotide metabolic processGO:00061631460.016
Human
regulation of cellular protein metabolic processGO:00322682430.016
Human
cellular amine metabolic processGO:0044106120.016
camera type eye developmentGO:004301040.016
apoptotic processGO:00069151590.016
single organism cellular localizationGO:19025801800.015
cellular response to ionizing radiationGO:0071479150.015
mrna processingGO:00063971040.015
regulation of purine nucleotide metabolic processGO:1900542620.015
multicellular organism growthGO:0035264460.015
growthGO:00400073590.015
regulation of cysteine type endopeptidase activityGO:2000116270.015
gliogenesisGO:0042063800.015
protein maturationGO:0051604710.015
purine ribonucleoside metabolic processGO:00461281270.014
Human
positive regulation of organelle organizationGO:0010638650.014
regulation of proteolysisGO:0030162870.014
regulation of intracellular signal transductionGO:19025312360.014
reproductive structure developmentGO:0048608740.014
nucleoside phosphate metabolic processGO:00067531620.014
Human Yeast
nucleotide catabolic processGO:00091661090.014
Human
negative regulation of cellular protein metabolic processGO:0032269850.014
oxoacid metabolic processGO:00434361030.014
cellular macromolecule catabolic processGO:00442651360.014
Yeast
regulation of response to stressGO:00801342000.014
organelle localizationGO:00516401480.013
nucleoside metabolic processGO:00091161270.013
Human
cellular amino acid metabolic processGO:0006520610.013
cellular protein modification processGO:00064644380.013
Human
wnt signaling pathwayGO:0016055980.013
cellular homeostasisGO:0019725800.013
regulation of neurogenesisGO:00507671580.013
regulation of mitotic recombinationGO:000001910.013
protein localizationGO:00081042840.013
organonitrogen compound catabolic processGO:19015651280.013
Human
amine metabolic processGO:0009308120.013
endocytosisGO:00068973100.012
organophosphate catabolic processGO:00464341120.012
Human
pigmentationGO:0043473750.012
nucleoside monophosphate metabolic processGO:0009123520.012
Human
mapk cascadeGO:00001651070.012
purine containing compound metabolic processGO:00725211550.012
Human
mitotic sister chromatid segregationGO:0000070870.012
lymph gland developmentGO:0048542280.012
dorsal ventral pattern formationGO:00099531330.012
positive regulation of immune system processGO:0002684680.012
imaginal disc derived wing morphogenesisGO:00074763370.011
negative regulation of biosynthetic processGO:00098902770.011
Human
lateral inhibitionGO:00463312060.011
negative regulation of protein metabolic processGO:0051248850.011
regulation of phosphatase activityGO:001092130.011
cellular catabolic processGO:00442483720.011
Human Yeast
regulation of anatomical structure morphogenesisGO:00226032420.011
cellular ketone metabolic processGO:0042180240.011
muscle organ developmentGO:00075171270.011
negative regulation of multicellular organismal processGO:00512411420.011
regulation of organelle organizationGO:00330431960.011
organelle assemblyGO:00709251980.011
regulation of innate immune responseGO:0045088710.011
negative regulation of catalytic activityGO:0043086420.011
female meiosis chromosome segregationGO:0016321330.011
regulation of defense responseGO:00313471020.011
camera type eye morphogenesisGO:004859320.011
protein complex assemblyGO:00064612000.011
cellular response to oxygen containing compoundGO:1901701790.011
purine ribonucleoside triphosphate catabolic processGO:00092071080.011
Human
anterior posterior axis specificationGO:00099481090.011
embryonic pattern specificationGO:00098801740.011
organic substance catabolic processGO:19015753080.011
Human Yeast
response to caffeineGO:0031000120.011
ribonucleoside catabolic processGO:00424541120.011
Human
negative regulation of transcription dna templatedGO:00458922370.011
negative regulation of cellular component organizationGO:00511291080.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.010
Human
regulation of cellular catabolic processGO:00313291570.010
regulation of molecular functionGO:00650092170.010
Human
purine nucleoside triphosphate metabolic processGO:00091441190.010
Human
purine nucleotide catabolic processGO:00061951090.010
Human

mre11 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.028
disease of cellular proliferationDOID:1456600.028
thoracic cancerDOID:509300.028
organ system cancerDOID:005068600.028