Drosophila melanogaster

74 known processes

AIF (Dmel_CG7263)

Apoptosis inducing factor

(Aliases: DmAIF,CG7263,Dmel\CG7263)

AIF biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
defense response to fungusGO:0050832480.396
response to external biotic stimulusGO:00432072930.355
regulation of transcription from rna polymerase ii promoterGO:00063573780.338
eye developmentGO:00016543230.293
regulation of lamellipodium organizationGO:1902743150.258
endocytosisGO:00068973100.210
Worm
homeostatic processGO:00425921990.185
transcription from rna polymerase ii promoterGO:00063663680.181
response to other organismGO:00517072930.157
response to fungusGO:0009620500.155
tube morphogenesisGO:00352391910.146
defense responseGO:00069523000.137
defense response to other organismGO:00985422250.123
positive regulation of biosynthetic processGO:00098913160.112
programmed cell deathGO:00125012570.108
nucleotide metabolic processGO:00091171610.093
enzyme linked receptor protein signaling pathwayGO:00071671790.093
protein modification processGO:00362114380.090
regulation of immune responseGO:00507761180.075
embryo development ending in birth or egg hatchingGO:00097921520.075
Worm
sensory organ morphogenesisGO:00905962600.075
digestive tract developmentGO:00485651490.072
gonad developmentGO:0008406500.070
digestive tract morphogenesisGO:00485461270.068
protein modification by small protein conjugationGO:0032446790.063
catabolic processGO:00090564090.062
Mouse Worm
cell deathGO:00082192790.059
anatomical structure homeostasisGO:0060249970.056
positive regulation of rna metabolic processGO:00512542710.056
vesicle mediated transportGO:00161923810.054
Worm
sex differentiationGO:0007548810.052
cellular protein modification processGO:00064644380.052
purine ribonucleotide metabolic processGO:00091501450.051
negative regulation of immune system processGO:0002683500.051
macromolecule catabolic processGO:00090571610.048
Mouse Worm
regulation of catalytic activityGO:00507901850.048
positive regulation of response to stimulusGO:00485843230.047
development of primary sexual characteristicsGO:0045137500.043
protein catabolic processGO:00301631010.043
regulation of cell deathGO:00109411730.042
Mouse
positive regulation of growthGO:0045927750.042
ribonucleoside triphosphate metabolic processGO:00091991190.041
digestive system developmentGO:00551231490.040
positive regulation of atp catabolic processGO:190329130.039
positive regulation of rna biosynthetic processGO:19026802660.039
organelle fusionGO:0048284460.039
organophosphate metabolic processGO:00196371950.039
regulation of immune system processGO:00026821760.036
positive regulation of catabolic processGO:00098961050.036
purine nucleoside metabolic processGO:00422781270.034
gastrulationGO:0007369700.034
negative regulation of cellular metabolic processGO:00313243820.033
tube developmentGO:00352952440.032
purine nucleoside monophosphate metabolic processGO:0009126500.032
positive regulation of nucleic acid templated transcriptionGO:19035082660.032
columnar cuboidal epithelial cell developmentGO:00020662490.031
deathGO:00162652840.031
ion transportGO:00068111450.031
single organism behaviorGO:00447083910.031
negative regulation of programmed cell deathGO:0043069720.031
positive regulation of cellular biosynthetic processGO:00313283160.030
innate immune responseGO:00450871440.029
phagocytosisGO:00069092150.029
lipid biosynthetic processGO:0008610460.029
regulation of intracellular signal transductionGO:19025312360.028
negative regulation of nucleic acid templated transcriptionGO:19035072400.028
reproductive structure developmentGO:0048608740.028
positive regulation of developmental growthGO:0048639620.028
nucleoside triphosphate catabolic processGO:00091431080.027
organic substance transportGO:00717022570.027
protein complex assemblyGO:00064612000.027
leucine transportGO:001582030.027
regulation of defense responseGO:00313471020.027
phosphatidylinositol mediated signalingGO:004801540.026
regulation of catabolic processGO:00098941700.026
Mouse
detection of stimulus involved in sensory perceptionGO:0050906920.025
multicellular organismal agingGO:00102591400.025
regulation of growthGO:00400082330.025
protein modification by small protein conjugation or removalGO:00706471060.025
glutamate secretionGO:001404710.025
positive regulation of cell communicationGO:00106472500.024
purine nucleotide metabolic processGO:00061631460.024
membrane disassemblyGO:003039740.024
regulation of phosphate metabolic processGO:00192202100.024
atp metabolic processGO:0046034490.024
regulation of molecular functionGO:00650092170.023
negative regulation of cell deathGO:0060548810.023
regulation of phosphorus metabolic processGO:00511742100.023
endomembrane system organizationGO:00102561190.023
hematopoietic progenitor cell differentiationGO:000224410.022
positive regulation of macromolecule biosynthetic processGO:00105572830.022
imaginal disc derived leg morphogenesisGO:0007480800.022
regulation of anatomical structure morphogenesisGO:00226032420.022
oxidation reduction processGO:00551141230.022
positive regulation of signal transductionGO:00099672230.021
reproductive system developmentGO:0061458740.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.021
regulation of response to stressGO:00801342000.021
glycosyl compound metabolic processGO:19016571270.020
glycosyl compound catabolic processGO:19016581120.020
secretion by cellGO:00329401010.020
Worm
chemical homeostasisGO:0048878920.020
positive regulation of cellular catabolic processGO:0031331950.020
positive regulation of multicellular organismal processGO:00512401430.020
positive regulation of nitrogen compound metabolic processGO:00511733540.020
defense response to gram negative bacteriumGO:0050829940.020
cell type specific apoptotic processGO:0097285380.020
Mouse
eye antennal disc developmentGO:0035214600.020
mitotic dna integrity checkpointGO:0044774750.020
positive regulation of gene expressionGO:00106282900.020
defense response to bacteriumGO:00427421780.019
response to biotic stimulusGO:00096072940.019
regulation of neuron apoptotic processGO:0043523160.019
response to bacteriumGO:00096171980.019
lipid metabolic processGO:00066291210.019
sphingolipid metabolic processGO:0006665190.019
negative regulation of transcription dna templatedGO:00458922370.019
organonitrogen compound metabolic processGO:19015643180.018
cellular response to chemical stimulusGO:00708871990.018
developmental growthGO:00485892800.018
cell motilityGO:00488702510.018
immune responseGO:00069552460.018
positive regulation of developmental processGO:00510941430.018
membrane lipid metabolic processGO:0006643220.017
ribonucleotide metabolic processGO:00092591450.017
nucleolus organizationGO:000700040.017
secretionGO:00469031090.017
Worm
establishment of localization in cellGO:00516494020.016
Worm
carbohydrate derivative metabolic processGO:19011352170.016
immune system processGO:00023763470.016
multi organism reproductive behaviorGO:00447051210.016
response to temperature stimulusGO:00092661060.016
salivary gland developmentGO:00074311620.016
regulation of meiosisGO:004002030.016
purine ribonucleoside monophosphate metabolic processGO:0009167500.016
determination of adult lifespanGO:00083401370.016
regulation of developmental growthGO:00486381740.016
nucleoside monophosphate metabolic processGO:0009123520.015
regulation of nucleotide catabolic processGO:0030811480.015
single organism intracellular transportGO:19025822070.015
positive regulation of signalingGO:00230562430.015
agingGO:00075681430.015
positive regulation of macromolecule metabolic processGO:00106044050.015
regulation of cellular component biogenesisGO:00440872010.015
hemopoiesisGO:0030097460.015
decapentaplegic signaling pathwayGO:0008101190.014
compound eye morphogenesisGO:00017452490.014
membrane fusionGO:0061025420.014
organelle fissionGO:00482853400.014
establishment of protein localizationGO:00451841630.014
cytoplasmic transportGO:00164821300.014
carbohydrate metabolic processGO:0005975820.014
cation transportGO:00068121100.014
regulation of innate immune responseGO:0045088710.014
inositol lipid mediated signalingGO:004801740.014
purine ribonucleoside triphosphate metabolic processGO:00092051190.014
nucleoside phosphate catabolic processGO:19012921100.013
negative regulation of protein metabolic processGO:0051248850.013
vesicle organizationGO:0016050440.013
positive regulation of nucleobase containing compound metabolic processGO:00459353320.013
cellular lipid metabolic processGO:0044255830.013
nucleoside triphosphate metabolic processGO:00091411200.013
gastrulation involving germ band extensionGO:0010004360.013
positive regulation of programmed cell deathGO:0043068620.013
negative regulation of biosynthetic processGO:00098902770.013
positive regulation of catalytic activityGO:00430851180.013
single organism membrane organizationGO:0044802930.013
regulation of cellular catabolic processGO:00313291570.013
Mouse
ribonucleoside catabolic processGO:00424541120.013
leucine importGO:006035630.013
mitotic nuclear divisionGO:00070672130.012
nephron epithelium developmentGO:007200930.012
cell agingGO:000756920.012
bmp signaling pathwayGO:0030509270.012
intracellular transportGO:00469072280.012
cellular catabolic processGO:00442483720.012
Mouse Worm
regulation of apoptotic processGO:00429811300.012
Mouse
glycoprotein biosynthetic processGO:0009101410.012
multicellular organismal homeostasisGO:0048871410.011
organic acid metabolic processGO:00060821030.011
tissue homeostasisGO:0001894360.011
notch signaling pathwayGO:00072191200.011
cellular macromolecule catabolic processGO:00442651360.011
Mouse Worm
energy derivation by oxidation of organic compoundsGO:0015980320.011
peripheral nervous system developmentGO:0007422520.011
organonitrogen compound biosynthetic processGO:19015661170.011
regulation of organelle organizationGO:00330431960.011
learning or memoryGO:00076111410.011
regulation of bmp signaling pathwayGO:0030510230.011
macromolecular complex assemblyGO:00650032560.011
positive regulation of cellular component organizationGO:00511301560.011
positive regulation of protein catabolic processGO:0045732340.011
nucleotide catabolic processGO:00091661090.011
negative regulation of oskar mrna translationGO:000731950.011
cardiovascular system developmentGO:0072358820.010
organophosphate catabolic processGO:00464341120.010
extrinsic apoptotic signaling pathwayGO:009719110.010
regulation of neuron deathGO:1901214260.010
nucleobase containing small molecule metabolic processGO:00550861740.010
aromatic compound catabolic processGO:00194391660.010
Mouse Worm
regulation of programmed cell deathGO:00430671520.010
Mouse

AIF disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.018
nervous system diseaseDOID:86300.018
disease of anatomical entityDOID:700.018
sensory system diseaseDOID:005015500.016
cancerDOID:16200.014
organ system cancerDOID:005068600.014
eye diseaseDOID:561400.013
eye and adnexa diseaseDOID:149200.013