Drosophila melanogaster

83 known processes

Hel25E (Dmel_CG7269)

Helicase at 25E

(Aliases: DmRH4,l(2)gdh-12,Dbp25F,uap56,sz,l(2)25Eb,l(2)jf26,WM6,hel,Wm6,Hel,UAP56,CG7269,l(2)k11511,l(2)gdh12,HEL,jf26,Dmel\CG7269)

Hel25E biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
pole plasm mrna localizationGO:0019094490.999
pole plasm oskar mrna localizationGO:0045451460.993
pole plasm rna localizationGO:0007316520.992
oocyte differentiationGO:00099941450.991
oocyte developmentGO:00485991240.989
oocyte anterior posterior axis specificationGO:0007314720.985
oocyte axis specificationGO:00073091080.985
oocyte constructionGO:00073081120.978
maternal determination of anterior posterior axis embryoGO:0008358740.976
embryonic pattern specificationGO:00098801740.974
pole plasm assemblyGO:0007315610.971
rna localizationGO:00064031150.961
cytoplasm organizationGO:0007028640.956
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.947
blastoderm segmentationGO:00073501590.945
negative regulation of rna biosynthetic processGO:19026792400.943
Yeast
tripartite regional subdivisionGO:00073511030.917
embryonic axis specificationGO:00005781070.911
intracellular mrna localizationGO:0008298660.894
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.890
Yeast
cellular macromolecule localizationGO:00707272200.887
negative regulation of nitrogen compound metabolic processGO:00511722650.879
Yeast
regionalizationGO:00030024160.867
negative regulation of rna metabolic processGO:00512532510.856
Yeast
intracellular mrna localization involved in pattern specification processGO:0060810560.852
negative regulation of transcription dna templatedGO:00458922370.834
Yeast
cell maturationGO:00484691440.821
axis specificationGO:00097981670.803
regulation of gene expression epigeneticGO:00400291280.728
Yeast
nucleobase containing compound catabolic processGO:00346551650.725
Human Yeast
cell deathGO:00082192790.706
Worm
negative regulation of cellular biosynthetic processGO:00313272770.679
Yeast
segmentationGO:00352822070.674
protein dna complex subunit organizationGO:0071824860.672
single organism cellular localizationGO:19025801800.618
heterocycle catabolic processGO:00467001660.613
Human Yeast
rna splicingGO:0008380830.611
chromatin silencingGO:0006342760.579
Yeast
organic substance catabolic processGO:19015753080.571
Human Yeast
anterior posterior pattern specificationGO:00099521360.562
negative regulation of cellular metabolic processGO:00313243820.552
Yeast
negative regulation of gene expressionGO:00106293870.542
Yeast
immune system processGO:00023763470.540
heterochromatin organizationGO:0070828250.517
programmed cell deathGO:00125012570.516
Worm
mrna metabolic processGO:00160711240.511
regulation of cell deathGO:00109411730.494
organic cyclic compound catabolic processGO:19013611680.488
Human Yeast
nuclear transcribed mrna catabolic processGO:0000956240.486
cellular nitrogen compound catabolic processGO:00442701650.465
Human Yeast
aromatic compound catabolic processGO:00194391660.460
Human Yeast
rna catabolic processGO:0006401370.458
developmental maturationGO:00217001720.458
anterior posterior axis specification embryoGO:00085951030.419
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.414
cellular macromolecule catabolic processGO:00442651360.405
regulation of response to stressGO:00801342000.398
Human
deathGO:00162652840.396
Worm
establishment of localization in cellGO:00516494020.385
mrna catabolic processGO:0006402330.384
negative regulation of gene expression epigeneticGO:0045814770.378
Yeast
larval developmentGO:00021641040.371
Worm
negative regulation of macromolecule biosynthetic processGO:00105582700.366
Yeast
anterior posterior axis specificationGO:00099481090.364
regulation of apoptotic processGO:00429811300.360
negative regulation of nucleobase containing compound metabolic processGO:00459342610.354
Yeast
regulation of intracellular signal transductionGO:19025312360.340
macromolecule catabolic processGO:00090571610.336
apoptotic processGO:00069151590.334
Worm
positive regulation of gene expressionGO:00106282900.322
Human
muscle structure developmentGO:00610612240.299
chromatin assembly or disassemblyGO:0006333520.286
positive regulation of rna metabolic processGO:00512542710.282
Human
cellular catabolic processGO:00442483720.281
Human Yeast
cellular response to dna damage stimulusGO:00069742230.281
Human Yeast
defense responseGO:00069523000.279
mrna processingGO:00063971040.275
positive regulation of macromolecule metabolic processGO:00106044050.264
Human
chemotaxisGO:00069352490.263
gene silencingGO:00164581380.262
Yeast
regulation of gene silencingGO:0060968630.255
negative regulation of cell cycle processGO:00109481090.254
Human
regulation of cell differentiationGO:00455953020.235
regulation of programmed cell deathGO:00430671520.232
nuclear transcribed mrna catabolic process nonsense mediated decayGO:000018480.230
chromatin organizationGO:00063252070.223
negative regulation of cell cycle phase transitionGO:19019881030.215
sex differentiationGO:0007548810.213
Worm
stem cell differentiationGO:00488631170.208
regulation of protein metabolic processGO:00512462560.207
defense response to other organismGO:00985422250.203
g2 dna damage checkpointGO:0031572690.203
regulation of rna splicingGO:0043484690.202
multi organism reproductive behaviorGO:00447051210.199
histone acetylationGO:0016573380.194
regulation of transcription from rna polymerase ii promoterGO:00063573780.186
regulation of mrna processingGO:0050684710.181
regulation of cell cycle processGO:00105641810.179
Human
intracellular signal transductionGO:00355563000.177
regulation of multicellular organismal developmentGO:20000264140.176
macromolecular complex assemblyGO:00650032560.172
Human
negative regulation of mitotic cell cycle phase transitionGO:19019911030.170
cellular macromolecular complex assemblyGO:00346221530.168
Human
rna splicing via transesterification reactionsGO:0000375730.167
catabolic processGO:00090564090.158
Human Yeast
reproductive behaviorGO:00190981220.158
enzyme linked receptor protein signaling pathwayGO:00071671790.150
oxoacid metabolic processGO:00434361030.148
dna conformation changeGO:00711031050.148
response to biotic stimulusGO:00096072940.140
reproductive structure developmentGO:0048608740.139
Worm
embryo development ending in birth or egg hatchingGO:00097921520.130
Worm
negative regulation of nucleic acid templated transcriptionGO:19035072400.129
Yeast
regulation of reproductive processGO:2000241540.129
mitotic g2 dna damage checkpointGO:0007095690.122
single organism behaviorGO:00447083910.120
mrna splicing via spliceosomeGO:0000398730.120
transcription from rna polymerase ii promoterGO:00063663680.118
Yeast
mitotic dna damage checkpointGO:0044773740.118
nucleoside metabolic processGO:00091161270.118
Human Yeast
neuron projection guidanceGO:00974852410.117
meiotic cell cycleGO:00513211710.114
histone methylationGO:0016571400.113
mitotic dna integrity checkpointGO:0044774750.110
small molecule metabolic processGO:00442813050.110
Human Yeast
positive regulation of biosynthetic processGO:00098913160.110
Human
gonad developmentGO:0008406500.109
Worm
positive regulation of transcription dna templatedGO:00458932660.106
Human
organophosphate metabolic processGO:00196371950.106
Human Yeast
posttranscriptional gene silencingGO:0016441460.105
response to other organismGO:00517072930.103
regulation of mitotic cell cycleGO:00073461900.102
regulation of mrna splicing via spliceosomeGO:0048024640.100
negative regulation of biosynthetic processGO:00098902770.098
Yeast
carboxylic acid metabolic processGO:0019752920.095
atp dependent chromatin remodelingGO:0043044220.090
anatomical structure homeostasisGO:0060249970.087
regulation of meiosisGO:004002030.081
positive regulation of nitrogen compound metabolic processGO:00511733540.081
Human
chromosome organizationGO:00512763600.080
camera type eye developmentGO:004301040.080
gene silencing by mirnaGO:0035195220.079
regulation of localizationGO:00328792750.077
dna packagingGO:0006323910.076
regulation of mitotic cell cycle phase transitionGO:19019901300.072
positive regulation of protein metabolic processGO:00512471280.071
regulation of cellular catabolic processGO:00313291570.070
dendrite guidanceGO:0070983210.069
positive regulation of macromolecule biosynthetic processGO:00105572830.068
Human
cellular response to chemical stimulusGO:00708871990.067
response to external biotic stimulusGO:00432072930.066
regulation of cellular protein metabolic processGO:00322682430.066
chromatin assemblyGO:0031497480.065
retina development in camera type eyeGO:006004140.064
positive regulation of cellular protein metabolic processGO:00322701180.063
nucleobase containing small molecule metabolic processGO:00550861740.062
Human Yeast
peptidyl lysine acetylationGO:0018394390.062
nucleosome organizationGO:0034728590.062
positive regulation of nucleic acid templated transcriptionGO:19035082660.061
Human
dna integrity checkpointGO:0031570810.061
Human
mitotic cell cycle checkpointGO:0007093880.060
response to organic substanceGO:00100332840.059
determination of adult lifespanGO:00083401370.059
negative regulation of developmental processGO:00510932010.058
development of primary sexual characteristicsGO:0045137500.057
Worm
regulation of multi organism processGO:00439001310.057
cellular ketone metabolic processGO:0042180240.057
mitotic g2 m transition checkpointGO:0044818700.056
positive regulation of cell deathGO:0010942690.055
cell cycle phase transitionGO:00447701400.055
posttranscriptional regulation of gene expressionGO:00106081450.054
innate immune responseGO:00450871440.053
dna metabolic processGO:00062592270.050
Yeast
positive regulation of response to stimulusGO:00485843230.050
genitalia developmentGO:0048806260.050
Worm
cell divisionGO:00513012480.048
regulation of organelle organizationGO:00330431960.047
reproductive system developmentGO:0061458740.047
Worm
chromatin remodelingGO:0006338720.046
cell proliferationGO:00082832990.046
rna processingGO:00063961470.044
positive regulation of programmed cell deathGO:0043068620.044
cell motilityGO:00488702510.042
male gamete generationGO:00482322010.041
dna damage checkpointGO:0000077780.041
Human
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.041
positive regulation of rna biosynthetic processGO:19026802660.040
Human
multicellular organismal reproductive behaviorGO:00330571100.040
regulation of catabolic processGO:00098941700.040
regulation of transcription by chromatin organizationGO:003440130.040
regulation of mrna metabolic processGO:1903311720.040
regulation of proteolysisGO:0030162870.039
spindle organizationGO:00070512530.039
dendrite morphogenesisGO:00488131990.038
neurological system processGO:00508773580.037
organonitrogen compound metabolic processGO:19015643180.037
Human Yeast
glycosyl compound catabolic processGO:19016581120.037
Human Yeast
regulation of cell proliferationGO:00421271630.035
nucleoside phosphate metabolic processGO:00067531620.035
Human Yeast
organic acid metabolic processGO:00060821030.034
regulation of chromatin silencingGO:0031935360.033
body morphogenesisGO:001017120.032
Worm
nitrogen compound transportGO:0071705850.032
peptidyl lysine trimethylationGO:001802360.032
taxisGO:00423303040.032
regulation of immune system processGO:00026821760.032
gene silencing by rnaGO:0031047570.031
purine nucleoside metabolic processGO:00422781270.031
Human Yeast
multi organism behaviorGO:00517051750.031
ribonucleoside monophosphate catabolic processGO:0009158390.030
Human Yeast
meiotic nuclear divisionGO:00071261510.030
chromatin modificationGO:00165681470.029
purine nucleoside monophosphate catabolic processGO:0009128380.029
Human Yeast
negative regulation of mitotic cell cycleGO:00459301090.028
organelle assemblyGO:00709251980.027
negative regulation of apoptotic processGO:0043066630.027
muscle organ developmentGO:00075171270.026
organelle fissionGO:00482853400.026
regulation of cell cycleGO:00517262910.026
Human
regulation of alternative mrna splicing via spliceosomeGO:0000381600.026
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.026
cellular homeostasisGO:0019725800.026
alternative mrna splicing via spliceosomeGO:0000380600.025
intracellular transportGO:00469072280.025
ribose phosphate metabolic processGO:00196931450.025
Human Yeast
positive regulation of defense responseGO:0031349590.025
nucleotide metabolic processGO:00091171610.025
Human Yeast
response to dsrnaGO:0043331150.025
mitotic cell cycle phase transitionGO:00447721380.024
cell type specific apoptotic processGO:0097285380.024
axonogenesisGO:00074092900.023
nuclear divisionGO:00002803320.023
regulation of meiotic cell cycleGO:005144590.023
negative regulation of cell cycleGO:00457861160.022
Human
cytoplasmic transportGO:00164821300.022
nucleoside phosphate catabolic processGO:19012921100.022
Human Yeast
response to bacteriumGO:00096171980.022
positive regulation of molecular functionGO:00440931360.022
peptidyl lysine modificationGO:0018205570.022
positive regulation of apoptotic processGO:0043065470.022
regulation of cellular ketone metabolic processGO:001056530.022
organic substance transportGO:00717022570.022
negative regulation of cell deathGO:0060548810.021
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.021
regulation of translationGO:0006417560.021
single organism catabolic processGO:00447122280.021
Human Yeast
positive regulation of cellular component organizationGO:00511301560.020
protein localizationGO:00081042840.020
regulation of oocyte developmentGO:0060281270.020
positive regulation of nucleobase containing compound metabolic processGO:00459353320.020
Human
regulation of cellular localizationGO:00603411360.020
multi multicellular organism processGO:00447061230.020
cellular response to organic substanceGO:00713101320.019
prostanoid biosynthetic processGO:004645710.019
immune responseGO:00069552460.019
spinal cord developmentGO:002151010.019
cell migrationGO:00164772380.019
ras protein signal transductionGO:0007265880.018
negative regulation of cell differentiationGO:00455961430.018
ovipositionGO:0018991190.018
organonitrogen compound catabolic processGO:19015651280.017
Human Yeast
histone h4 k20 methylationGO:003477040.017
purine ribonucleoside monophosphate catabolic processGO:0009169380.017
Human Yeast
mitotic nuclear divisionGO:00070672130.017
regulation of dna metabolic processGO:0051052340.017
chromatin silencing at centromereGO:003070230.016
vesicle mediated transportGO:00161923810.016
phosphorylationGO:00163102940.016
response to abiotic stimulusGO:00096283410.016
nucleobase containing compound transportGO:0015931560.016
cellular amino acid metabolic processGO:0006520610.016
protein maturationGO:0051604710.015
defense response to bacteriumGO:00427421780.015
axon developmentGO:00615642970.015
negative regulation of cellular component organizationGO:00511291080.015
cognitionGO:00508901410.015
regulation of cellular component biogenesisGO:00440872010.015
regulation of dna templated transcription elongationGO:0032784170.015
Human
positive regulation of chromatin silencingGO:0031937160.015
response to nitrogen compoundGO:1901698900.015
ribonucleoside monophosphate metabolic processGO:0009161510.014
Human Yeast
cellular protein complex assemblyGO:0043623710.014
carbohydrate derivative metabolic processGO:19011352170.014
Human Yeast
agingGO:00075681430.014
regulation of protein modification processGO:00313991120.014
ribonucleoside catabolic processGO:00424541120.014
Human Yeast
regulation of small gtpase mediated signal transductionGO:0051056930.014
cell cycle checkpointGO:0000075950.014
Human
golgi organizationGO:0007030660.014
response to temperature stimulusGO:00092661060.014
oocyte dorsal ventral axis specificationGO:0007310340.014
regulation of phosphate metabolic processGO:00192202100.014
regulation of phosphatase activityGO:001092130.014
multicellular organismal agingGO:00102591400.014
cell chemotaxis involved in malpighian tubule morphogenesisGO:006135230.014
endocytosisGO:00068973100.014
purine nucleoside monophosphate metabolic processGO:0009126500.014
Human Yeast
protein complex biogenesisGO:00702712010.013
response to nutrient levelsGO:00316671140.013
ribonucleoprotein complex subunit organizationGO:0071826280.013
Human
cellular response to nitrogen compoundGO:1901699510.013
eye morphogenesisGO:00485922600.013
glycosyl compound metabolic processGO:19016571270.013
Human Yeast
spermatogenesisGO:00072832000.013
response to heatGO:0009408630.013
positive regulation of intracellular signal transductionGO:19025331160.013
mitotic spindle organizationGO:00070522200.013
peptidyl lysine methylationGO:0018022160.012
nucleoside triphosphate catabolic processGO:00091431080.012
Human Yeast
protein localization to organelleGO:0033365820.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
Human Yeast
nucleoside monophosphate metabolic processGO:0009123520.012
Human Yeast
purine ribonucleotide metabolic processGO:00091501450.012
Human Yeast
dendrite developmentGO:00163582040.012
purine ribonucleoside monophosphate metabolic processGO:0009167500.012
Human Yeast
regulation of cellular response to stressGO:0080135890.012
Human
negative regulation of organelle organizationGO:0010639560.012
regulation of cell maturationGO:1903429270.012
regulation of cell cycle phase transitionGO:19019871300.012
axon guidanceGO:00074112330.012
response to oxygen containing compoundGO:19017002000.012
ribonucleotide catabolic processGO:00092611090.012
Human Yeast
regulation of cell developmentGO:00602842150.012
chemosensory behaviorGO:00076351060.012
positive regulation of ribosome biogenesisGO:009007030.011
response to extracellular stimulusGO:00099911160.011
small gtpase mediated signal transductionGO:0007264880.011
ubiquitin dependent protein catabolic processGO:0006511780.011
phagocytosisGO:00069092150.011
cellular response to dsrnaGO:0071359150.011
mapk cascadeGO:00001651070.011
formation of a compartment boundaryGO:006028840.011
homeostatic processGO:00425921990.011
regulation of transportGO:00510491810.011
histone exchangeGO:0043486210.011
nucleoside monophosphate catabolic processGO:0009125390.011
Human Yeast
negative regulation of cellular protein metabolic processGO:0032269850.011
positive regulation of cell communicationGO:00106472500.011
regulation of striated muscle contractionGO:000694220.010
regulation of nuclear divisionGO:0051783580.010
tricarboxylic acid metabolic processGO:007235010.010
regulation of ras protein signal transductionGO:0046578930.010
reactive oxygen species biosynthetic processGO:190340900.010

Hel25E disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.043
disease of cellular proliferationDOID:1456600.013
cancerDOID:16200.013