Drosophila melanogaster

156 known processes

RanGap (Dmel_CG9999)

Ran GTPase activating protein

(Aliases: Scl,Dmel\CG9999,rangap,Ran,RanGap1,Sd-RanGAP,RanGAP,CT28175,CG9999,Sd-RanGap,ranGap,dRanGAP,Sd,ranGAP,SD)

RanGap biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
meiotic nuclear divisionGO:00071261510.990
meiotic cell cycleGO:00513211710.978
cell cycle checkpointGO:0000075950.978
organelle fissionGO:00482853400.965
nuclear divisionGO:00002803320.932
mitotic cell cycle checkpointGO:0007093880.811
embryo development ending in birth or egg hatchingGO:00097921520.750
establishment of localization in cellGO:00516494020.728
mitotic spindle organizationGO:00070522200.714
protein localizationGO:00081042840.695
microtubule organizing center organizationGO:00310231680.672
organic substance transportGO:00717022570.660
regulation of catabolic processGO:00098941700.646
meiotic cell cycle processGO:19030461320.597
negative regulation of mitotic cell cycleGO:00459301090.505
regulation of cell differentiationGO:00455953020.501
negative regulation of mitotic cell cycle phase transitionGO:19019911030.486
cellular catabolic processGO:00442483720.484
spindle assemblyGO:0051225800.483
mitotic g2 m transition checkpointGO:0044818700.451
negative regulation of cell cycle phase transitionGO:19019881030.430
protein importGO:0017038550.424
meiotic chromosome segregationGO:0045132590.399
catabolic processGO:00090564090.397
glycosyl compound catabolic processGO:19016581120.394
gonad developmentGO:0008406500.394
mitotic cell cycle phase transitionGO:00447721380.393
negative regulation of cell cycle processGO:00109481090.384
regulation of cell cycle phase transitionGO:19019871300.370
dna integrity checkpointGO:0031570810.364
larval developmentGO:00021641040.361
mitotic dna integrity checkpointGO:0044774750.360
regulation of mitotic cell cycle phase transitionGO:19019901300.355
regulation of cellular catabolic processGO:00313291570.354
mitotic g2 dna damage checkpointGO:0007095690.343
regulation of cell cycle processGO:00105641810.333
establishment of protein localizationGO:00451841630.312
reproductive system developmentGO:0061458740.309
sex differentiationGO:0007548810.308
regulation of cell cycleGO:00517262910.292
centrosome organizationGO:00512971630.290
cellular macromolecule localizationGO:00707272200.278
determination of adult lifespanGO:00083401370.277
negative regulation of cell cycleGO:00457861160.269
regulation of developmental growthGO:00486381740.269
reproductive structure developmentGO:0048608740.255
negative regulation of gene expressionGO:00106293870.254
protein localization to organelleGO:0033365820.247
growthGO:00400073590.247
spindle organizationGO:00070512530.245
agingGO:00075681430.241
regulation of cell divisionGO:0051302720.239
mitotic dna damage checkpointGO:0044773740.235
regulation of mitotic cell cycleGO:00073461900.224
centrosome cycleGO:00070981370.214
g2 dna damage checkpointGO:0031572690.212
dna damage checkpointGO:0000077780.209
gene silencingGO:00164581380.198
regulation of meiosisGO:004002030.192
regulation of neurogenesisGO:00507671580.189
protein modification by small protein conjugation or removalGO:00706471060.188
positive regulation of growthGO:0045927750.185
female meiotic divisionGO:0007143700.185
positive regulation of proteolysisGO:0045862520.184
multicellular organism growthGO:0035264460.184
cell cycle phase transitionGO:00447701400.184
nucleoside triphosphate catabolic processGO:00091431080.183
multicellular organismal agingGO:00102591400.181
single organism catabolic processGO:00447122280.180
genitalia developmentGO:0048806260.179
regulation of growthGO:00400082330.177
gene silencing by rnaGO:0031047570.169
regulation of multicellular organismal developmentGO:20000264140.161
nuclear importGO:0051170510.152
response to other organismGO:00517072930.151
negative regulation of nucleobase containing compound metabolic processGO:00459342610.138
protein targeting to nucleusGO:0044744510.134
nucleoside metabolic processGO:00091161270.134
protein targetingGO:0006605640.134
regulation of nucleocytoplasmic transportGO:0046822350.129
Human
single organism nuclear importGO:1902593510.129
purine ribonucleoside triphosphate metabolic processGO:00092051190.123
cell migrationGO:00164772380.119
neuron recognitionGO:00080381010.119
protein localization to nucleusGO:0034504550.118
establishment of protein localization to organelleGO:0072594620.117
regulation of organelle organizationGO:00330431960.117
nucleotide metabolic processGO:00091171610.117
regulation of cell deathGO:00109411730.115
protein modification by small protein conjugationGO:0032446790.115
spindle assembly involved in mitosisGO:0090307500.114
purine ribonucleoside metabolic processGO:00461281270.113
modification dependent macromolecule catabolic processGO:0043632790.110
chromosome segregationGO:00070591570.108
positive regulation of endopeptidase activityGO:0010950260.108
negative regulation of cellular metabolic processGO:00313243820.106
protein complex biogenesisGO:00702712010.104
macromolecular complex assemblyGO:00650032560.100
intracellular transportGO:00469072280.099
negative regulation of developmental processGO:00510932010.096
regulation of intracellular transportGO:0032386640.093
Human
protein import into nucleusGO:0006606510.092
negative regulation of cellular component organizationGO:00511291080.092
macromolecule catabolic processGO:00090571610.091
positive regulation of multicellular organism growthGO:0040018210.091
organophosphate metabolic processGO:00196371950.091
developmental growthGO:00485892800.089
organelle assemblyGO:00709251980.087
nucleocytoplasmic transportGO:0006913720.085
cell divisionGO:00513012480.084
heterocycle catabolic processGO:00467001660.081
purine nucleoside metabolic processGO:00422781270.079
regulation of meiotic cell cycleGO:005144590.079
cellular nitrogen compound catabolic processGO:00442701650.078
cytoplasmic transportGO:00164821300.077
development of primary sexual characteristicsGO:0045137500.077
metaphase anaphase transition of mitotic cell cycleGO:0007091280.074
positive regulation of nitrogen compound metabolic processGO:00511733540.073
negative regulation of cellular biosynthetic processGO:00313272770.071
single organism cellular localizationGO:19025801800.070
positive regulation of nucleocytoplasmic transportGO:0046824240.069
organic substance catabolic processGO:19015753080.069
ribonucleotide catabolic processGO:00092611090.067
cell deathGO:00082192790.067
chromosome organizationGO:00512763600.066
intracellular protein transportGO:00068861040.065
body morphogenesisGO:001017120.065
positive regulation of hydrolase activityGO:0051345780.065
oocyte maturationGO:000155630.063
dendrite developmentGO:00163582040.063
response to external biotic stimulusGO:00432072930.061
regulation of protein localizationGO:0032880760.061
Human
mitotic nuclear divisionGO:00070672130.061
deathGO:00162652840.060
regulation of cellular localizationGO:00603411360.060
Human
regulation of protein metabolic processGO:00512462560.059
regulation of multicellular organism growthGO:0040014400.058
cellular protein localizationGO:00346131600.057
dendrite morphogenesisGO:00488131990.056
response to biotic stimulusGO:00096072940.055
positive regulation of catabolic processGO:00098961050.055
positive regulation of developmental processGO:00510941430.054
axon developmentGO:00615642970.054
nucleoside phosphate metabolic processGO:00067531620.053
nucleus organizationGO:0006997450.053
protein transportGO:00150311550.052
protein complex assemblyGO:00064612000.052
cellular protein complex assemblyGO:0043623710.050
negative regulation of nitrogen compound metabolic processGO:00511722650.050
protein ubiquitinationGO:0016567700.049
glycosyl compound metabolic processGO:19016571270.049
positive regulation of macromolecule metabolic processGO:00106044050.049
negative regulation of catabolic processGO:0009895360.047
ribonucleoside catabolic processGO:00424541120.046
cellular macromolecule catabolic processGO:00442651360.046
male gamete generationGO:00482322010.046
posttranscriptional gene silencingGO:0016441460.045
purine ribonucleoside catabolic processGO:00461301120.044
regulation of cellular protein catabolic processGO:1903362440.043
regulation of transportGO:00510491810.043
Human
response to oxidative stressGO:0006979860.043
organic cyclic compound catabolic processGO:19013611680.043
rna interferenceGO:0016246270.043
chromatin remodelingGO:0006338720.042
guanosine containing compound metabolic processGO:1901068740.042
regulation of cellular protein metabolic processGO:00322682430.041
regulation of nuclear divisionGO:0051783580.041
regulation of cell proliferationGO:00421271630.040
nuclear transportGO:0051169720.040
nucleoside triphosphate metabolic processGO:00091411200.040
negative regulation of sister chromatid segregationGO:0033046130.040
ubiquitin dependent protein catabolic processGO:0006511780.039
nucleoside catabolic processGO:00091641120.039
posttranscriptional regulation of gene expressionGO:00106081450.038
endocytosisGO:00068973100.038
nucleobase containing small molecule metabolic processGO:00550861740.038
regulation of protein localization to nucleusGO:1900180290.038
regulation of hemocyte proliferationGO:0035206370.037
positive regulation of multicellular organismal processGO:00512401430.037
microtubule cytoskeleton organization involved in mitosisGO:1902850520.036
nucleoside phosphate catabolic processGO:19012921100.036
maintenance of locationGO:0051235730.035
regulation of phosphate metabolic processGO:00192202100.035
defense response to bacteriumGO:00427421780.035
purine ribonucleotide metabolic processGO:00091501450.034
purine containing compound catabolic processGO:00725231120.033
regulation of proteolysisGO:0030162870.033
cell proliferationGO:00082832990.033
homeostatic processGO:00425921990.032
regulation of proteolysis involved in cellular protein catabolic processGO:1903050440.032
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.032
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.032
metaphase anaphase transition of cell cycleGO:0044784280.031
camera type eye developmentGO:004301040.031
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.031
apoptotic processGO:00069151590.031
dna replicationGO:0006260480.031
regulation of transcription elongation from rna polymerase ii promoterGO:0034243150.030
chromatin organizationGO:00063252070.030
positive regulation of molecular functionGO:00440931360.030
response to ketoneGO:1901654340.030
pronuclear migrationGO:003504640.030
purine nucleotide catabolic processGO:00061951090.030
regulation of protein transportGO:0051223570.029
Human
positive regulation of cellular protein metabolic processGO:00322701180.029
positive regulation of protein import into nucleusGO:0042307210.028
regulation of molecular functionGO:00650092170.027
positive regulation of cellular catabolic processGO:0031331950.027
positive regulation of i kappab kinase nf kappab signalingGO:004312310.026
aromatic compound catabolic processGO:00194391660.026
response to sterolGO:0036314340.026
regulation of cytoplasmic transportGO:1903649470.026
Human
negative regulation of cell differentiationGO:00455961430.026
dna templated transcription elongationGO:0006354180.025
regulation of cdc42 protein signal transductionGO:003248930.025
carbohydrate derivative metabolic processGO:19011352170.025
carbohydrate derivative catabolic processGO:19011361180.025
ribose phosphate metabolic processGO:00196931450.025
positive regulation of transcription factor import into nucleusGO:0042993190.025
proteolysisGO:00065081920.025
positive regulation of phosphate metabolic processGO:00459371390.025
epithelial cell differentiationGO:00308553220.025
response to oxygen containing compoundGO:19017002000.023
programmed cell deathGO:00125012570.023
response to organic cyclic compoundGO:0014070890.023
muscle organ developmentGO:00075171270.023
positive regulation of intracellular protein transportGO:0090316300.022
defense responseGO:00069523000.022
mrna catabolic processGO:0006402330.022
induction of programmed cell death by hormonesGO:0035081120.022
multi multicellular organism processGO:00447061230.022
ribonucleoside triphosphate metabolic processGO:00091991190.022
defense response to other organismGO:00985422250.021
double strand break repair via homologous recombinationGO:0000724130.021
eggshell formationGO:00307031050.021
cellular macromolecular complex assemblyGO:00346221530.021
negative regulation of purine nucleotide catabolic processGO:003312210.021
small gtpase mediated signal transductionGO:0007264880.020
negative regulation of cellular catabolic processGO:0031330340.020
proteasomal protein catabolic processGO:0010498590.020
regulation of protein catabolic processGO:0042176550.020
multicellular organismal reproductive behaviorGO:00330571100.020
purine nucleoside triphosphate metabolic processGO:00091441190.020
salivary gland morphogenesisGO:00074351450.020
rna phosphodiester bond hydrolysis exonucleolyticGO:009050340.020
positive regulation of mrna processingGO:005068540.019
regulation of gene expression epigeneticGO:00400291280.019
regulation of intracellular protein transportGO:0033157460.019
Human
cytokinesisGO:0000910900.019
gland developmentGO:00487321910.019
formation of a compartment boundaryGO:006028840.019
organophosphate catabolic processGO:00464341120.019
small molecule metabolic processGO:00442813050.019
positive regulation of cellular component organizationGO:00511301560.018
positive regulation of catalytic activityGO:00430851180.018
regulation of response to stressGO:00801342000.018
single organism intracellular transportGO:19025822070.018
ribonucleoside triphosphate catabolic processGO:00092031080.018
regulation of neuron differentiationGO:00456641030.018
negative regulation of proteolysis involved in cellular protein catabolic processGO:1903051170.018
dna recombinationGO:0006310320.018
regulation of localizationGO:00328792750.018
Human
negative regulation of rna biosynthetic processGO:19026792400.017
response to organic substanceGO:00100332840.017
ribonucleotide metabolic processGO:00092591450.017
purine nucleoside triphosphate catabolic processGO:00091461080.017
cell cycle g1 s phase transitionGO:0044843310.017
nucleobase containing compound catabolic processGO:00346551650.017
establishment of organelle localizationGO:00516561220.017
spermatogenesisGO:00072832000.017
neuronal stem cell maintenanceGO:009715040.016
regulation of chromosome organizationGO:0033044640.016
regulation of defense responseGO:00313471020.016
regulation of ruffle assemblyGO:190002710.016
positive regulation of phosphorus metabolic processGO:00105621390.016
induction of programmed cell death by ecdysoneGO:0035078120.016
regulation of peptidase activityGO:0052547390.016
regulation of intracellular signal transductionGO:19025312360.015
phagocytosisGO:00069092150.015
regulation of proteasomal protein catabolic processGO:0061136390.015
regulation of apoptotic processGO:00429811300.015
regulation of striated muscle contractionGO:000694220.015
posttranscriptional gene silencing by rnaGO:0035194450.015
gliogenesisGO:0042063800.015
purine ribonucleoside triphosphate catabolic processGO:00092071080.015
positive regulation of transportGO:0051050920.015
mrna processingGO:00063971040.014
positive regulation of protein metabolic processGO:00512471280.014
negative regulation of cell proliferationGO:0008285690.014
mitotic sister chromatid segregationGO:0000070870.014
rna localizationGO:00064031150.014
oocyte axis specificationGO:00073091080.014
regulation of cellular component biogenesisGO:00440872010.014
regulation of hydrolase activityGO:0051336970.014
centrosome duplicationGO:00512981210.014
regulation of endopeptidase activityGO:0052548360.013
meiotic cytokinesisGO:0033206330.013
protein catabolic processGO:00301631010.013
response to ecdysoneGO:0035075340.013
purine nucleoside catabolic processGO:00061521120.013
establishment or maintenance of polarity of larval imaginal disc epitheliumGO:001633630.013
ribonucleoside metabolic processGO:00091191270.013
protein modification processGO:00362114380.013
regulation of multivesicular body sizeGO:001079630.013
progression of morphogenetic furrow involved in compound eye morphogenesisGO:000745880.013
cell recognitionGO:00080371020.013
regulation of phosphorus metabolic processGO:00511742100.013
regulation of sister chromatid segregationGO:0033045280.012
cellular protein catabolic processGO:0044257830.012
negative regulation of transcription factor import into nucleusGO:004299240.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
histone h3 k9 modificationGO:0061647120.012
negative regulation of biosynthetic processGO:00098902770.012
positive regulation of protein transportGO:0051222370.012
localization of cellGO:00516742570.012
regulation of response to external stimulusGO:00321011150.012
regulation of phosphatase activityGO:001092130.011
reproductive behaviorGO:00190981220.011
positive regulation of protein localization to nucleusGO:1900182210.011
fertilizationGO:0009566260.011
ecdysone mediated induction of salivary gland cell autophagic cell deathGO:0035072120.011
dna metabolic processGO:00062592270.011
establishment of mitotic spindle localizationGO:0040001170.011
nucleotide catabolic processGO:00091661090.011
intracellular signal transductionGO:00355563000.011
cellular response to organic substanceGO:00713101320.010
dorsal closure leading edge cell differentiationGO:004666320.010
positive regulation of neurogenesisGO:0050769410.010
asymmetric protein localizationGO:0008105330.010
chorion containing eggshell formationGO:00073041050.010
epithelial cell developmentGO:00020642740.010
pole cell formationGO:0007279190.010

RanGap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.016
cancerDOID:16200.015
disease of cellular proliferationDOID:1456600.015
respiratory system cancerDOID:005061500.015
organ system cancerDOID:005068600.015