Drosophila melanogaster

97 known processes

Hph (Dmel_CG31543)

HIF prolyl hydroxylase

(Aliases: anon-EST:Posey69,CG1114,CG14665,l(3)S030304,l(3)02255,31543,Dm.egl-9,hph,dHPH,Dmel\CG31543,CG31543,0303/04,fga,dmHPH)

Hph biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
trachea developmentGO:0060438290.986
ovarian follicle cell migrationGO:00072971210.981
epithelial cell migrationGO:00106311480.962
open tracheal system developmentGO:00074242040.928
tissue migrationGO:00901301550.828
epithelium migrationGO:00901321480.802
ameboidal type cell migrationGO:00016671510.716
respiratory system developmentGO:00605412130.712
border follicle cell migrationGO:00072981130.708
columnar cuboidal epithelial cell differentiationGO:00020652560.615
localization of cellGO:00516742570.572
cell migrationGO:00164772380.570
columnar cuboidal epithelial cell developmentGO:00020662490.541
trachea morphogenesisGO:0060439220.491
terminal branching open tracheal systemGO:0007430170.489
long term memoryGO:0007616620.430
deathGO:00162652840.401
Mouse
epithelial tube morphogenesisGO:0060562880.393
morphogenesis of an epitheliumGO:00020092760.355
regulation of developmental growthGO:00486381740.347
positive regulation of macromolecule metabolic processGO:00106044050.332
cognitionGO:00508901410.300
epithelial cell developmentGO:00020642740.281
programmed cell deathGO:00125012570.281
Mouse
single organism intracellular transportGO:19025822070.278
positive regulation of gtpase activityGO:0043547430.276
branching morphogenesis of an epithelial tubeGO:0048754450.274
ovarian follicle cell developmentGO:00307072480.245
establishment or maintenance of cell polarityGO:00071631670.231
positive regulation of nitrogen compound metabolic processGO:00511733540.190
transition metal ion homeostasisGO:0055076170.185
regulation of tor signalingGO:0032006210.169
gtp metabolic processGO:0046039720.163
learning or memoryGO:00076111410.161
positive regulation of phosphorylationGO:0042327870.160
protein localizationGO:00081042840.159
regulation of programmed cell deathGO:00430671520.150
Mouse
cell motilityGO:00488702510.144
single organism biosynthetic processGO:00447112060.137
positive regulation of catalytic activityGO:00430851180.136
regulation of cellular ketone metabolic processGO:001056530.134
regulation of organelle organizationGO:00330431960.131
cellular transition metal ion homeostasisGO:004691690.130
epithelial cell differentiationGO:00308553220.130
morphogenesis of a branching structureGO:0001763450.126
carbohydrate derivative metabolic processGO:19011352170.122
regulation of nucleotide metabolic processGO:0006140620.121
steroid biosynthetic processGO:0006694160.119
apoptotic signaling pathwayGO:0097190270.117
multicellular organism growthGO:0035264460.113
small molecule metabolic processGO:00442813050.104
Worm
regulation of cellular amino acid metabolic processGO:000652100.102
branching involved in open tracheal system developmentGO:0060446450.098
positive regulation of nucleic acid templated transcriptionGO:19035082660.098
larval developmentGO:00021641040.094
organic cyclic compound catabolic processGO:19013611680.094
proteolysisGO:00065081920.093
positive regulation of cellular amine metabolic processGO:003324000.093
regulation of cell proliferationGO:00421271630.091
Mouse
cellular component disassemblyGO:0022411460.091
negative regulation of developmental processGO:00510932010.091
ribonucleotide catabolic processGO:00092611090.088
forebrain developmentGO:003090020.086
tube morphogenesisGO:00352391910.084
positive regulation of cellular biosynthetic processGO:00313283160.084
extracellular structure organizationGO:0043062460.080
regulation of cell migrationGO:0030334220.080
nucleobase containing compound catabolic processGO:00346551650.080
cellular ketone metabolic processGO:0042180240.079
gtp catabolic processGO:0006184720.077
nucleotide metabolic processGO:00091171610.074
regulation of response to stressGO:00801342000.074
enzyme linked receptor protein signaling pathwayGO:00071671790.074
aromatic compound catabolic processGO:00194391660.073
positive regulation of phosphate metabolic processGO:00459371390.072
organic acid metabolic processGO:00060821030.071
Worm
small gtpase mediated signal transductionGO:0007264880.070
nucleotide catabolic processGO:00091661090.069
morphogenesis of a branching epitheliumGO:0061138450.069
positive regulation of transcription dna templatedGO:00458932660.068
positive regulation of cellular amino acid metabolic processGO:004576400.068
positive regulation of mapk cascadeGO:0043410630.067
regulation of cellular response to hypoxiaGO:190003730.067
regulation of purine nucleotide metabolic processGO:1900542620.066
regulation of cell sizeGO:0008361630.066
positive regulation of rna metabolic processGO:00512542710.066
response to radiationGO:00093141550.064
homeostatic processGO:00425921990.064
negative regulation of programmed cell deathGO:0043069720.064
positive regulation of rab gtpase activityGO:003285170.063
regulation of apoptotic processGO:00429811300.062
Mouse
regulation of transcription from rna polymerase ii promoterGO:00063573780.062
lipid biosynthetic processGO:0008610460.061
actin polymerization or depolymerizationGO:0008154310.061
nucleoside phosphate catabolic processGO:19012921100.061
actin filament bundle organizationGO:0061572280.060
establishment or maintenance of apical basal cell polarityGO:0035088340.060
o glycan processingGO:001626630.060
purine ribonucleoside triphosphate metabolic processGO:00092051190.060
regulation of gtp catabolic processGO:0033124440.059
protein polymerizationGO:0051258420.059
regulation of anatomical structure sizeGO:00900661630.059
regulation of protein modification processGO:00313991120.058
single organism catabolic processGO:00447122280.058
single organism behaviorGO:00447083910.057
tube developmentGO:00352952440.057
organelle assemblyGO:00709251980.057
regulation of growthGO:00400082330.057
protein modification processGO:00362114380.056
positive regulation of phosphorus metabolic processGO:00105621390.055
purine nucleoside triphosphate metabolic processGO:00091441190.055
tissue morphogenesisGO:00487292970.054
heart processGO:0003015370.053
oxoacid metabolic processGO:00434361030.053
Worm
intercellular bridge organizationGO:0043063140.053
regulation of actin filament based processGO:0032970420.052
negative regulation of microtubule depolymerizationGO:0007026210.052
purine nucleoside triphosphate catabolic processGO:00091461080.051
positive regulation of rna biosynthetic processGO:19026802660.050
regulation of cellular catabolic processGO:00313291570.050
actin filament organizationGO:00070151260.050
regulation of catalytic activityGO:00507901850.050
regulation of blood circulationGO:1903522210.049
regulation of gtpase activityGO:0043087440.049
purine ribonucleoside triphosphate catabolic processGO:00092071080.049
regulation of jnk cascadeGO:0046328400.048
purine nucleotide catabolic processGO:00061951090.048
convergent extensionGO:006002620.047
hormone biosynthetic processGO:0042446200.046
regulation of rab protein signal transductionGO:003248370.046
ras protein signal transductionGO:0007265880.046
regulation of multicellular organism growthGO:0040014400.045
stem cell maintenanceGO:0019827670.045
positive regulation of signalingGO:00230562430.045
response to abiotic stimulusGO:00096283410.045
catabolic processGO:00090564090.045
actin cytoskeleton organizationGO:00300362060.045
positive regulation of protein phosphorylationGO:0001934340.044
memoryGO:0007613940.044
digestive system developmentGO:00551231490.044
multicellular organismal homeostasisGO:0048871410.043
ribose phosphate metabolic processGO:00196931450.043
response to external biotic stimulusGO:00432072930.043
carboxylic acid metabolic processGO:0019752920.042
Worm
organic substance transportGO:00717022570.042
organophosphate metabolic processGO:00196371950.042
regulation of cellular component sizeGO:0032535980.042
negative regulation of glial cell proliferationGO:006025360.042
positive regulation of response to stimulusGO:00485843230.041
positive regulation of cell migrationGO:003033520.041
spindle organizationGO:00070512530.041
hormone metabolic processGO:0042445330.040
ribonucleoside triphosphate catabolic processGO:00092031080.040
regulation of stem cell proliferationGO:0072091400.040
nucleoside phosphate metabolic processGO:00067531620.039
regulation of rab gtpase activityGO:003231370.039
organic substance catabolic processGO:19015753080.038
cellular homeostasisGO:0019725800.038
cytoplasmic transportGO:00164821300.037
rab protein signal transductionGO:003248260.037
positive regulation of developmental growthGO:0048639620.037
regulation of ras gtpase activityGO:0032318380.037
guanosine containing compound catabolic processGO:1901069740.037
chemical homeostasisGO:0048878920.037
endomembrane system organizationGO:00102561190.036
positive regulation of nucleobase containing compound metabolic processGO:00459353320.036
cell deathGO:00082192790.036
Mouse
gliogenesisGO:0042063800.035
response to bacteriumGO:00096171980.035
lipid metabolic processGO:00066291210.035
actin filament based processGO:00300292200.035
cellular response to peptideGO:1901653280.034
regulation of phosphorus metabolic processGO:00511742100.034
establishment of localization in cellGO:00516494020.034
spindle assembly involved in mitosisGO:0090307500.034
regulation of defense responseGO:00313471020.034
cellular catabolic processGO:00442483720.033
response to organic substanceGO:00100332840.033
secretionGO:00469031090.033
nucleobase containing small molecule metabolic processGO:00550861740.033
positive regulation of transportGO:0051050920.033
mitotic spindle organizationGO:00070522200.033
purine nucleotide metabolic processGO:00061631460.032
tor signalingGO:0031929320.032
organonitrogen compound metabolic processGO:19015643180.032
Worm
heterocycle catabolic processGO:00467001660.032
dorsal trunk growth open tracheal systemGO:003500170.031
regulation of cellular response to stressGO:0080135890.031
purine containing compound catabolic processGO:00725231120.031
ribonucleoside triphosphate metabolic processGO:00091991190.031
positive regulation of macromolecule biosynthetic processGO:00105572830.031
positive regulation of cellular component biogenesisGO:0044089800.031
regulation of cellular amine metabolic processGO:003323830.030
positive regulation of cell motilityGO:200014730.030
positive regulation of programmed cell deathGO:0043068620.030
regulation of cytoskeleton organizationGO:0051493890.030
organophosphate catabolic processGO:00464341120.030
small molecule biosynthetic processGO:0044283370.030
response to extracellular stimulusGO:00099911160.029
sterol homeostasisGO:005509240.029
positive regulation of cell sizeGO:0045793210.029
regulation of catabolic processGO:00098941700.029
embryonic organ developmentGO:0048568500.029
Mouse
regulation of protein complex disassemblyGO:0043244290.029
regulation of transportGO:00510491810.029
telencephalon developmentGO:002153720.028
positive regulation of cellular protein metabolic processGO:00322701180.028
photoreceptor cell differentiationGO:00465301700.028
negative regulation of cell proliferationGO:0008285690.028
female germ line cyst encapsulationGO:004813980.028
regulation of intracellular signal transductionGO:19025312360.028
regulation of response to nutrient levelsGO:0032107180.028
ribonucleoside metabolic processGO:00091191270.027
negative regulation of apoptotic processGO:0043066630.027
nucleoside catabolic processGO:00091641120.027
striated muscle cell developmentGO:0055002500.027
cytoplasmic transport nurse cell to oocyteGO:0007303120.027
regulation of malpighian tubule diameterGO:003529730.027
positive regulation of kinase activityGO:0033674250.027
positive regulation of nucleotide catabolic processGO:0030813460.026
ribonucleotide metabolic processGO:00092591450.026
r8 cell fate specificationGO:004546450.026
cellular protein modification processGO:00064644380.026
regulation of actin cytoskeleton organizationGO:0032956420.026
filtration diaphragm assemblyGO:003605840.026
regulation of glial cell proliferationGO:0060251110.025
nucleoside triphosphate metabolic processGO:00091411200.025
response to glucoseGO:000974920.025
cellular amino acid metabolic processGO:0006520610.025
Worm
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.025
regulation of cell deathGO:00109411730.025
Mouse
regulation of endopeptidase activityGO:0052548360.024
regulation of nucleotide catabolic processGO:0030811480.024
regulation of microtubule cytoskeleton organizationGO:0070507410.024
regulation of neuron deathGO:1901214260.024
Mouse
establishment or maintenance of bipolar cell polarityGO:0061245340.024
regulation of actin polymerization or depolymerizationGO:0008064270.024
chromatin modificationGO:00165681470.024
intracellular signal transductionGO:00355563000.024
cellular protein localizationGO:00346131600.024
periodic partitioningGO:0007365290.024
microtubule depolymerizationGO:0007019250.024
response to hexoseGO:000974630.023
protein localization to nucleusGO:0034504550.023
carbohydrate metabolic processGO:0005975820.023
ovarian nurse cell to oocyte transportGO:0007300270.023
developmental growthGO:00485892800.023
regulation of cell motilityGO:2000145230.023
spindle assemblyGO:0051225800.023
detection of abiotic stimulusGO:0009582660.023
phagocytosisGO:00069092150.023
positive regulation of cell deathGO:0010942690.023
positive regulation of gtp catabolic processGO:0033126430.023
apoptotic processGO:00069151590.023
Mouse
regulation of cell developmentGO:00602842150.022
cell growthGO:00160491080.022
purine ribonucleotide catabolic processGO:00091541090.022
positive regulation of signal transductionGO:00099672230.022
intracellular transportGO:00469072280.022
regulation of cell growthGO:0001558430.022
response to nutrient levelsGO:00316671140.022
intrinsic apoptotic signaling pathwayGO:0097193160.022
peptidyl tyrosine modificationGO:0018212240.021
positive regulation of intracellular signal transductionGO:19025331160.021
stem cell differentiationGO:00488631170.021
skeletal muscle fiber developmentGO:004874130.021
ribonucleoside catabolic processGO:00424541120.021
regulation of synapse organizationGO:00508071100.021
regulation of dna templated transcription elongationGO:0032784170.021
regulation of purine nucleotide catabolic processGO:0033121480.021
positive regulation of purine nucleotide metabolic processGO:1900544550.021
regulation of molecular functionGO:00650092170.021
regulation of heart rateGO:0002027110.021
post embryonic hemopoiesisGO:0035166170.020
transcription from rna polymerase ii promoterGO:00063663680.020
regulation of secretionGO:0051046440.020
mapk cascadeGO:00001651070.020
regulation of localizationGO:00328792750.020
Worm
regulation of tube architecture open tracheal systemGO:0035152680.020
negative regulation of response to stimulusGO:00485852580.020
glycosyl compound metabolic processGO:19016571270.019
autophagic vacuole assemblyGO:000004520.019
maintenance of cell polarityGO:0030011180.019
synaptic transmissionGO:00072682880.019
positive regulation of nucleotide metabolic processGO:0045981550.019
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.019
cellular metal ion homeostasisGO:0006875310.019
vesicle mediated transportGO:00161923810.019
regulation of hormone levelsGO:0010817400.019
regulation of protein metabolic processGO:00512462560.019
negative regulation of growthGO:0045926840.018
peripheral nervous system developmentGO:0007422520.018
positive regulation of cellular component organizationGO:00511301560.018
response to osmotic stressGO:0006970140.018
myotube cell developmentGO:001490430.018
membrane fusionGO:0061025420.018
negative regulation of organ growthGO:0046621150.018
connective tissue developmentGO:006144830.018
positive regulation of peptidase activityGO:0010952290.018
tracheal outgrowth open tracheal systemGO:0007426180.018
establishment of organelle localizationGO:00516561220.018
regulation of mapk cascadeGO:0043408920.018
amine metabolic processGO:0009308120.017
camera type eye developmentGO:004301040.017
spiracle morphogenesis open tracheal systemGO:0035277220.017
response to hypoxiaGO:0001666530.017
chaeta developmentGO:0022416970.017
single organism cellular localizationGO:19025801800.017
gene silencingGO:00164581380.017
protein import into nucleusGO:0006606510.017
anatomical structure homeostasisGO:0060249970.017
regulation of cell substrate adhesionGO:001081020.017
regulation of heart contractionGO:0008016210.017
regulation of system processGO:0044057360.017
morphogenesis of follicular epitheliumGO:0016333360.017
positive regulation of molecular functionGO:00440931360.017
cellular nitrogen compound catabolic processGO:00442701650.017
embryonic morphogenesisGO:00485982060.017
learningGO:0007612750.017
regulation of neurogenesisGO:00507671580.017
cellular response to decreased oxygen levelsGO:0036294300.017
signal transduction by phosphorylationGO:00230141070.016
neurological system processGO:00508773580.016
mitotic cell cycle embryonicGO:0045448380.016
response to ionizing radiationGO:0010212320.016
nucleoside metabolic processGO:00091161270.016
cation homeostasisGO:0055080510.016
golgi vesicle transportGO:0048193270.016
regulation of actin filament polymerizationGO:0030833250.016
peptidyl tyrosine phosphorylationGO:0018108240.016
nitrogen compound transportGO:0071705850.016
response to mechanical stimulusGO:0009612280.016
positive regulation of protein kinase activityGO:0045860250.016
torc1 signalingGO:0038202120.016
endosomal vesicle fusionGO:003405840.016
glial cell developmentGO:0021782270.016
heart contractionGO:0060047260.016
response to hormoneGO:0009725450.015
macroautophagyGO:0016236420.015
positive regulation of cysteine type endopeptidase activityGO:2001056240.015
gastrulation with mouth forming firstGO:0001703360.015
nuclear importGO:0051170510.015
macromolecular complex disassemblyGO:0032984370.015
stem cell developmentGO:0048864790.015
single organism membrane organizationGO:0044802930.015
growthGO:00400073590.015
negative regulation of cell deathGO:0060548810.015
eye pigmentationGO:0048069430.015
regulation of small gtpase mediated signal transductionGO:0051056930.015
cholesterol homeostasisGO:004263230.015
cellular response to carbohydrate stimulusGO:007132240.014
regulation of tube length open tracheal systemGO:0035159240.014
defense response to gram positive bacteriumGO:0050830410.014
negative regulation of protein depolymerizationGO:1901880230.014
cation transportGO:00068121100.014
actin filament polymerizationGO:0030041270.014
purine containing compound metabolic processGO:00725211550.014
branch fusion open tracheal systemGO:0035147170.014
hindgut developmentGO:0061525580.014
regulation of cell projection organizationGO:0031344920.014
cellular response to molecule of bacterial originGO:007121930.014
secretion by cellGO:00329401010.014
cell cell junction organizationGO:0045216550.014
ecdysis chitin based cuticleGO:001899080.014
cell cell signaling involved in cell fate commitmentGO:00451682100.013
response to decreased oxygen levelsGO:0036293580.013
positive regulation of lipid metabolic processGO:004583440.013
positive regulation of organelle organizationGO:0010638650.013
regulation of protein polymerizationGO:0032271280.013
outflow tract morphogenesisGO:000315140.013
purine ribonucleoside metabolic processGO:00461281270.013
apical junction assemblyGO:0043297320.013
morphogenesis of a polarized epitheliumGO:0001738930.013
positive regulation of cell communicationGO:00106472500.013
regulation of nucleoside metabolic processGO:0009118500.013
cellular response to hormone stimulusGO:0032870440.013
regulation of imaginal disc growthGO:0045570260.013
detection of external stimulusGO:0009581660.013
microtubule polymerization or depolymerizationGO:0031109390.013
axonogenesisGO:00074092900.013
nuclear transportGO:0051169720.013
regulation of cellular protein metabolic processGO:00322682430.013
germline ring canal formationGO:0030725130.013
regulation of actin filament lengthGO:0030832270.013
cellular response to endogenous stimulusGO:0071495800.013
regulation of cellular localizationGO:00603411360.013
protein targeting to nucleusGO:0044744510.013
negative regulation of nitrogen compound metabolic processGO:00511722650.013
carbohydrate homeostasisGO:0033500120.013
fusome organizationGO:0045478130.012
cellular chemical homeostasisGO:0055082400.012
response to insulinGO:0032868290.012
response to lipopolysaccharideGO:003249640.012
regulation of cell adhesionGO:0030155270.012
embryo development ending in birth or egg hatchingGO:00097921520.012
Mouse
regulation of locomotionGO:0040012420.012
negative regulation of developmental growthGO:0048640640.012
synapse assemblyGO:00074161430.012
peptidyl amino acid modificationGO:00181931050.012
regulation of cellular component movementGO:0051270420.012
single organismal cell cell adhesionGO:0016337450.012
nucleobase containing compound transportGO:0015931560.012
regulation of protein depolymerizationGO:1901879270.012
regulation of secretion by cellGO:1903530390.012
positive regulation of gene expressionGO:00106282900.012
regulation of protein acetylationGO:190198370.012
cellular amine metabolic processGO:0044106120.012
extracellular matrix constituent secretionGO:007027840.012
epithelial cell migration open tracheal systemGO:0007427320.012
response to alkaloidGO:0043279260.012
positive regulation of purine nucleotide catabolic processGO:0033123460.012
positive regulation of protein modification processGO:0031401580.012
phosphorylationGO:00163102940.012
regulation of lipid kinase activityGO:004355020.011
response to endogenous stimulusGO:00097191190.011
metal ion transportGO:0030001740.011
positive regulation of endopeptidase activityGO:0010950260.011
cell junction organizationGO:0034330570.011
regulation of nervous system developmentGO:00519602480.011
glycosyl compound catabolic processGO:19016581120.011
renal tubule developmentGO:0061326640.011
muscle cell differentiationGO:00426921030.011
regulation of phosphorylationGO:00423251470.011
lysosomal transportGO:0007041130.011
protein kinase b signalingGO:004349110.011
stress activated protein kinase signaling cascadeGO:0031098550.011
protein importGO:0017038550.011
cell type specific apoptotic processGO:0097285380.011
Mouse
retina development in camera type eyeGO:006004140.011
cellular response to oxygen levelsGO:0071453300.011
cellular response to chemical stimulusGO:00708871990.011
positive regulation of ras gtpase activityGO:0032320360.011
positive regulation of apoptotic processGO:0043065470.011
cellular response to organic substanceGO:00713101320.011
regulation of embryonic developmentGO:0045995680.011
membrane organizationGO:00610241120.011
response to peptideGO:1901652290.011
epiboly involved in wound healingGO:009050520.011
regulation of neuron apoptotic processGO:0043523160.011
Mouse
cytoskeleton dependent intracellular transportGO:0030705440.011
neuron fate specificationGO:0048665120.011
cellular protein complex assemblyGO:0043623710.010
purine ribonucleotide metabolic processGO:00091501450.010
single organism carbohydrate metabolic processGO:0044723720.010
photoreceptor cell developmentGO:0042461960.010
stem cell proliferationGO:0072089880.010
transition metal ion transportGO:0000041160.010
positive regulation of stem cell proliferationGO:200064880.010
asymmetric stem cell divisionGO:0098722490.010
genital disc developmentGO:0035215440.010
photoreceptor cell fate specificationGO:004370490.010
cell migration involved in gastrulationGO:004207490.010
olfactory learningGO:0008355560.010
regulation of phosphate metabolic processGO:00192202100.010
glycoprotein metabolic processGO:0009100410.010
regulation of peptidyl lysine acetylationGO:200075670.010
regulation of hydrolase activityGO:0051336970.010
regulation of immune responseGO:00507761180.010
lipid homeostasisGO:0055088330.010
striated muscle cell differentiationGO:0051146900.010
positive regulation of multicellular organism growthGO:0040018210.010
endocytosisGO:00068973100.010
mitochondrion organizationGO:0007005650.010

Hph disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.038
disease of metabolismDOID:001466700.011