IMP: Integrative Multi-species Prediction

Drosophila melanogaster

15 known processes

CG12325 (Dmel_CG12325)

CG12325 gene product from transcript CG12325-RA

(Aliases: Dmel\CG12325)

Entrez: 36144
FLYBASE: FBgn0033557
UniProtKB: Q5U0X8

Process Predictions
Disease Predictions

CG12325 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
rrna processing	GO:0006364	3	0.521	Yeast
rna processing	GO:0006396	147	0.462	Yeast
ribosomal large subunit biogenesis	GO:0042273	1	0.277
ncrna metabolic process	GO:0034660	43	0.200	Yeast
ribonucleoprotein complex biogenesis	GO:0022613	31	0.161	Yeast Zebrafish
snrna metabolic process	GO:0016073	14	0.083
larval development	GO:0002164	104	0.077	Worm
endocytosis	GO:0006897	310	0.075
regulation of mrna metabolic process	GO:1903311	72	0.065
regulation of mrna splicing via spliceosome	GO:0048024	64	0.063
vesicle mediated transport	GO:0016192	381	0.059
ncrna processing	GO:0034470	30	0.057	Yeast
regulation of rna splicing	GO:0043484	69	0.057
rna splicing via transesterification reactions with bulged adenosine as nucleophile	GO:0000377	73	0.052
regulation of mrna processing	GO:0050684	71	0.051
mrna metabolic process	GO:0016071	124	0.050
regulation of cell development	GO:0060284	215	0.049
organelle assembly	GO:0070925	198	0.048	Zebrafish
ribosome biogenesis	GO:0042254	8	0.048	Yeast Zebrafish
regulation of neuron differentiation	GO:0045664	103	0.048
multicellular organismal aging	GO:0010259	140	0.048
regulation of mitotic cell cycle	GO:0007346	190	0.046
regulation of cell cycle	GO:0051726	291	0.045
regulation of multicellular organismal development	GO:2000026	414	0.044
mrna processing	GO:0006397	104	0.043
positive regulation of multicellular organismal process	GO:0051240	143	0.039
dendrite development	GO:0016358	204	0.039
rna splicing	GO:0008380	83	0.037
macromolecular complex assembly	GO:0065003	256	0.033	Zebrafish
multi multicellular organism process	GO:0044706	123	0.033
regulation of cell cycle process	GO:0010564	181	0.033
regulation of cell differentiation	GO:0045595	302	0.032
regulation of nervous system development	GO:0051960	248	0.032
mrna splicing via spliceosome	GO:0000398	73	0.031
cellular macromolecule localization	GO:0070727	220	0.031
aging	GO:0007568	143	0.030
determination of adult lifespan	GO:0008340	137	0.030
snrna processing	GO:0016180	14	0.030
cell proliferation	GO:0008283	299	0.029
regulation of neurogenesis	GO:0050767	158	0.029
regulation of alternative mrna splicing via spliceosome	GO:0000381	60	0.028
regulation of protein metabolic process	GO:0051246	256	0.028
regulation of glial cell proliferation	GO:0060251	11	0.027
developmental growth	GO:0048589	280	0.026
positive regulation of developmental process	GO:0051094	143	0.025
rna splicing via transesterification reactions	GO:0000375	73	0.025
regulation of mrna 3 end processing	GO:0031440	7	0.024
striated muscle myosin thick filament assembly	GO:0071688	3	0.023
response to organic substance	GO:0010033	284	0.023
dendrite morphogenesis	GO:0048813	199	0.023
positive regulation of signaling	GO:0023056	243	0.023
wound healing	GO:0042060	75	0.022
positive regulation of signal transduction	GO:0009967	223	0.022
gene silencing	GO:0016458	138	0.022
regulation of cellular localization	GO:0060341	136	0.022
negative regulation of gene expression	GO:0010629	387	0.022
regulation of neuron projection development	GO:0010975	69	0.021
alternative mrna splicing via spliceosome	GO:0000380	60	0.021
immune system process	GO:0002376	347	0.021
protein localization	GO:0008104	284	0.021
growth	GO:0040007	359	0.021
multi organism behavior	GO:0051705	175	0.021
organic substance transport	GO:0071702	257	0.020
positive regulation of macromolecule metabolic process	GO:0010604	405	0.020
regulation of anatomical structure size	GO:0090066	163	0.020
phosphorylation	GO:0016310	294	0.020
positive regulation of cell communication	GO:0010647	250	0.020
organic substance catabolic process	GO:1901575	308	0.019
axon development	GO:0061564	297	0.019
posttranscriptional regulation of gene expression	GO:0010608	145	0.018
positive regulation of wnt signaling pathway	GO:0030177	25	0.018
regulation of transport	GO:0051049	181	0.018
positive regulation of mrna processing	GO:0050685	4	0.018
cellular macromolecular complex assembly	GO:0034622	153	0.018	Zebrafish
negative regulation of cell death	GO:0060548	81	0.017
cellular component assembly involved in morphogenesis	GO:0010927	151	0.017
positive regulation of response to stimulus	GO:0048584	323	0.017
positive regulation of cellular biosynthetic process	GO:0031328	316	0.016
epithelial cell differentiation	GO:0030855	322	0.016
regulation of histone deacetylation	GO:0031063	2	0.016
regulation of cell size	GO:0008361	63	0.016
ion transport	GO:0006811	145	0.016
imaginal disc derived appendage development	GO:0048737	399	0.016
regulation of localization	GO:0032879	275	0.016
negative regulation of cellular metabolic process	GO:0031324	382	0.015
axonogenesis	GO:0007409	290	0.015
stem cell proliferation	GO:0072089	88	0.015
notch signaling pathway	GO:0007219	120	0.015
rna localization	GO:0006403	115	0.015
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.015
response to wounding	GO:0009611	94	0.015
macromolecule catabolic process	GO:0009057	161	0.015
developmental cell growth	GO:0048588	52	0.014
single organism biosynthetic process	GO:0044711	206	0.014
positive regulation of transport	GO:0051050	92	0.014
multicellular organismal reproductive behavior	GO:0033057	110	0.014
nuclear import	GO:0051170	51	0.014
cell death	GO:0008219	279	0.014
positive regulation of mrna metabolic process	GO:1903313	5	0.014
ribonucleoprotein complex assembly	GO:0022618	23	0.014	Zebrafish
regulation of cellular protein metabolic process	GO:0032268	243	0.014
rna phosphodiester bond hydrolysis	GO:0090501	17	0.014	Yeast
negative regulation of cell cycle	GO:0045786	116	0.013
protein transport	GO:0015031	155	0.013
glial cell proliferation	GO:0014009	13	0.013
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.013
establishment or maintenance of cell polarity	GO:0007163	167	0.013	Yeast
regulation of cell proliferation	GO:0042127	163	0.013
cellular protein modification process	GO:0006464	438	0.013
kidney development	GO:0001822	3	0.013
regulation of molecular function	GO:0065009	217	0.013
defense response to bacterium	GO:0042742	178	0.013
negative regulation of mitotic cell cycle	GO:0045930	109	0.013
extrinsic apoptotic signaling pathway	GO:0097191	1	0.013
anatomical structure homeostasis	GO:0060249	97	0.012
negative regulation of rna metabolic process	GO:0051253	251	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
muscle structure development	GO:0061061	224	0.012
positive regulation of gene expression	GO:0010628	290	0.012
aromatic amino acid family metabolic process	GO:0009072	3	0.012
protein modification process	GO:0036211	438	0.012
spindle organization	GO:0007051	253	0.012
establishment of organelle localization	GO:0051656	122	0.012
cellular amino acid metabolic process	GO:0006520	61	0.012
cellular macromolecule catabolic process	GO:0044265	136	0.012
sex differentiation	GO:0007548	81	0.012
canonical wnt signaling pathway	GO:0060070	21	0.011
catecholamine biosynthetic process	GO:0042423	3	0.011
posttranscriptional gene silencing	GO:0016441	46	0.011
regulation of developmental growth	GO:0048638	174	0.011
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.011
cellular catabolic process	GO:0044248	372	0.011
mitotic spindle organization	GO:0007052	220	0.011
response to endogenous stimulus	GO:0009719	119	0.011
maintenance of location	GO:0051235	73	0.011
single organism intracellular transport	GO:1902582	207	0.011
single organism behavior	GO:0044708	391	0.011
regulation of intracellular transport	GO:0032386	64	0.011
compound eye morphogenesis	GO:0001745	249	0.011
negative regulation of signaling	GO:0023057	219	0.010
regulation of gene expression epigenetic	GO:0040029	128	0.010
digestive system development	GO:0055123	149	0.010	Zebrafish
secretion	GO:0046903	109	0.010
mitotic g2 m transition checkpoint	GO:0044818	70	0.010
positive regulation of rna metabolic process	GO:0051254	271	0.010
connective tissue development	GO:0061448	3	0.010
phagocytosis	GO:0006909	215	0.010
protein targeting	GO:0006605	64	0.010
positive regulation of immune response	GO:0050778	63	0.010
protein targeting to nucleus	GO:0044744	51	0.010
cellular protein localization	GO:0034613	160	0.010
regulation of epidermal growth factor receptor signaling pathway	GO:0042058	42	0.010
response to abiotic stimulus	GO:0009628	341	0.010
negative regulation of cell communication	GO:0010648	223	0.010

CG12325 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.046
eye and adnexa disease	DOID:1492	0.018
sensory system disease	DOID:0050155	0.018
nervous system disease	DOID:863	0.018
eye disease	DOID:5614	0.018

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