Drosophila melanogaster

40 known processes

Gen (Dmel_CG10670)

XPG-like endonuclease

(Aliases: DmGEN,BcDNA:GM10765,Dmel\CG10670,CG10670)

Gen biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
response to abiotic stimulusGO:00096283410.067
chromosome organizationGO:00512763600.063
chromosome segregationGO:00070591570.050
nuclear divisionGO:00002803320.043
spindle organizationGO:00070512530.041
regulation of cell cycleGO:00517262910.039
Human
proteolysisGO:00065081920.039
dna metabolic processGO:00062592270.037
positive regulation of nitrogen compound metabolic processGO:00511733540.035
compound eye developmentGO:00487493070.035
regulation of mitotic cell cycleGO:00073461900.032
Human
organic substance catabolic processGO:19015753080.032
heterocycle catabolic processGO:00467001660.032
regulation of cell cycle processGO:00105641810.032
Human
positive regulation of response to stimulusGO:00485843230.031
organonitrogen compound metabolic processGO:19015643180.031
single organism behaviorGO:00447083910.031
eye developmentGO:00016543230.031
ubiquitin dependent protein catabolic processGO:0006511780.030
organic substance transportGO:00717022570.030
negative regulation of gene expressionGO:00106293870.030
Human
regulation of organelle organizationGO:00330431960.030
Human
cellular catabolic processGO:00442483720.029
open tracheal system developmentGO:00074242040.028
sister chromatid segregationGO:0000819920.028
taxisGO:00423303040.028
small molecule metabolic processGO:00442813050.028
body morphogenesisGO:001017120.027
protein complex biogenesisGO:00702712010.027
mitotic spindle organizationGO:00070522200.027
positive regulation of nucleobase containing compound metabolic processGO:00459353320.026
intracellular transportGO:00469072280.026
protein modification processGO:00362114380.026
respiratory system developmentGO:00605412130.025
regulation of mitotic cell cycle phase transitionGO:19019901300.025
Human
mitotic cell cycle phase transitionGO:00447721380.025
chromosome separationGO:0051304420.024
macromolecule catabolic processGO:00090571610.024
negative regulation of cellular metabolic processGO:00313243820.024
Human
regulation of multicellular organismal developmentGO:20000264140.023
lateral inhibitionGO:00463312060.023
positive regulation of cellular biosynthetic processGO:00313283160.023
cell fate determinationGO:0001709910.023
cytoplasmic transportGO:00164821300.023
regulation of protein metabolic processGO:00512462560.023
Human
compound eye morphogenesisGO:00017452490.023
deathGO:00162652840.023
mitotic nuclear divisionGO:00070672130.023
dna repairGO:0006281540.022
imaginal disc derived appendage developmentGO:00487373990.022
regulation of cellular amine metabolic processGO:003323830.022
regulation of catabolic processGO:00098941700.022
Human
regulation of cellular protein metabolic processGO:00322682430.022
Human
positive regulation of macromolecule metabolic processGO:00106044050.022
appendage developmentGO:00487364010.022
appendage morphogenesisGO:00351073970.022
regulation of cellular catabolic processGO:00313291570.021
Human
catabolic processGO:00090564090.021
programmed cell deathGO:00125012570.021
eye morphogenesisGO:00485922600.021
amine metabolic processGO:0009308120.021
developmental growthGO:00485892800.021
regulation of intracellular signal transductionGO:19025312360.020
rna processingGO:00063961470.020
regulation of localizationGO:00328792750.020
organic cyclic compound catabolic processGO:19013611680.020
cellular protein catabolic processGO:0044257830.020
regulation of cell cycle phase transitionGO:19019871300.020
Human
intracellular signal transductionGO:00355563000.020
tissue morphogenesisGO:00487292970.020
camera type eye developmentGO:004301040.020
apoptotic processGO:00069151590.020
growthGO:00400073590.020
single organism intracellular transportGO:19025822070.020
adult behaviorGO:00305341370.020
positive regulation of cell communicationGO:00106472500.019
cell divisionGO:00513012480.019
regulation of microtubule based processGO:0032886490.019
Human
homeostatic processGO:00425921990.019
cell cycle phase transitionGO:00447701400.019
ion transportGO:00068111450.019
phagocytosisGO:00069092150.019
positive regulation of biosynthetic processGO:00098913160.019
positive regulation of signal transductionGO:00099672230.019
carboxylic acid metabolic processGO:0019752920.019
nucleoside triphosphate catabolic processGO:00091431080.019
regulation of transportGO:00510491810.019
cellular amine metabolic processGO:0044106120.019
dna conformation changeGO:00711031050.019
cell deathGO:00082192790.019
regulation of molecular functionGO:00650092170.019
carbohydrate derivative metabolic processGO:19011352170.019
modification dependent protein catabolic processGO:0019941780.018
negative regulation of response to stimulusGO:00485852580.018
vesicle mediated transportGO:00161923810.018
cellular protein modification processGO:00064644380.018
single organism catabolic processGO:00447122280.018
positive regulation of gene expressionGO:00106282900.018
organelle fissionGO:00482853400.018
organic acid metabolic processGO:00060821030.018
negative regulation of signal transductionGO:00099682060.018
imaginal disc derived appendage morphogenesisGO:00351143950.018
cellular response to dna damage stimulusGO:00069742230.018
morphogenesis of an epitheliumGO:00020092760.017
kidney developmentGO:000182230.017
positive regulation of rna biosynthetic processGO:19026802660.017
regulation of gene expression epigeneticGO:00400291280.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
sensory organ morphogenesisGO:00905962600.017
negative regulation of cell cycle processGO:00109481090.017
Human
cellular amino acid metabolic processGO:0006520610.017
regulation of phosphorus metabolic processGO:00511742100.017
post embryonic appendage morphogenesisGO:00351203850.017
macromolecular complex assemblyGO:00650032560.017
aromatic compound catabolic processGO:00194391660.017
protein localizationGO:00081042840.017
positive regulation of rna metabolic processGO:00512542710.017
oxoacid metabolic processGO:00434361030.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
regulation of programmed cell deathGO:00430671520.016
vitamin biosynthetic processGO:000911010.016
cellularizationGO:0007349900.016
regulation of response to stressGO:00801342000.016
organonitrogen compound catabolic processGO:19015651280.016
positive regulation of signalingGO:00230562430.016
immune responseGO:00069552460.016
anatomical structure homeostasisGO:0060249970.016
mrna metabolic processGO:00160711240.016
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.016
protein complex assemblyGO:00064612000.016
response to biotic stimulusGO:00096072940.016
nucleotide catabolic processGO:00091661090.016
regulation of cellular amino acid metabolic processGO:000652100.016
regulation of catalytic activityGO:00507901850.015
imaginal disc derived wing morphogenesisGO:00074763370.015
protein transportGO:00150311550.015
endocytosisGO:00068973100.015
response to other organismGO:00517072930.015
neurological system processGO:00508773580.015
transcription from rna polymerase ii promoterGO:00063663680.015
transmembrane transportGO:00550851390.015
cellular nitrogen compound catabolic processGO:00442701650.015
negative regulation of mitotic cell cycleGO:00459301090.015
Human
regulation of cellular ketone metabolic processGO:001056530.015
establishment or maintenance of cell polarityGO:00071631670.015
modification dependent macromolecule catabolic processGO:0043632790.015
protein catabolic processGO:00301631010.015
establishment of localization in cellGO:00516494020.015
cellular ketone metabolic processGO:0042180240.015
glycerolipid catabolic processGO:004650330.014
wing disc morphogenesisGO:00074723440.014
embryonic morphogenesisGO:00485982060.014
proteasomal protein catabolic processGO:0010498590.014
negative regulation of signalingGO:00230572190.014
nucleoside phosphate metabolic processGO:00067531620.014
organophosphate metabolic processGO:00196371950.014
small gtpase mediated signal transductionGO:0007264880.014
axon developmentGO:00615642970.014
gene silencingGO:00164581380.014
negative regulation of transcription dna templatedGO:00458922370.014
immune system processGO:00023763470.014
purine ribonucleotide metabolic processGO:00091501450.014
purine ribonucleoside triphosphate catabolic processGO:00092071080.014
response to organic substanceGO:00100332840.014
cell cell signaling involved in cell fate commitmentGO:00451682100.014
regulation of transcription from rna polymerase ii promoterGO:00063573780.014
connective tissue developmentGO:006144830.014
neutral lipid catabolic processGO:004646130.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
wnt signaling pathwayGO:0016055980.014
endomembrane system organizationGO:00102561190.014
mitotic cell cycle checkpointGO:0007093880.014
Human
mitotic dna integrity checkpointGO:0044774750.014
cellular macromolecule catabolic processGO:00442651360.014
compound eye photoreceptor cell differentiationGO:00017511400.014
cation transportGO:00068121100.014
response to temperature stimulusGO:00092661060.014
negative regulation of nucleic acid templated transcriptionGO:19035072400.014
negative regulation of cellular biosynthetic processGO:00313272770.014
cellular macromolecule localizationGO:00707272200.014
negative regulation of rna metabolic processGO:00512532510.014
single organism cellular localizationGO:19025801800.014
agingGO:00075681430.013
nucleoside phosphate catabolic processGO:19012921100.013
g protein coupled receptor signaling pathwayGO:00071861360.013
purine ribonucleoside metabolic processGO:00461281270.013
ribonucleotide metabolic processGO:00092591450.013
mrna processingGO:00063971040.013
axonogenesisGO:00074092900.013
response to lipopolysaccharideGO:003249640.013
gtp metabolic processGO:0046039720.013
regulation of response to external stimulusGO:00321011150.013
epithelial cell differentiationGO:00308553220.013
purine containing compound metabolic processGO:00725211550.013
phosphorylationGO:00163102940.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
positive regulation of transcription dna templatedGO:00458932660.013
notch signaling pathwayGO:00072191200.013
epithelial cell developmentGO:00020642740.013
cellular protein localizationGO:00346131600.013
regulation of hydrolase activityGO:0051336970.013
purine nucleotide metabolic processGO:00061631460.013
response to external biotic stimulusGO:00432072930.013
ribose phosphate metabolic processGO:00196931450.013
digestive tract morphogenesisGO:00485461270.013
negative regulation of biosynthetic processGO:00098902770.013
response to woundingGO:0009611940.013
negative regulation of cellular component organizationGO:00511291080.013
Human
negative regulation of cell cycle phase transitionGO:19019881030.012
Human
mitotic sister chromatid separationGO:0051306300.012
photoreceptor cell differentiationGO:00465301700.012
cation transmembrane transportGO:0098655880.012
membrane organizationGO:00610241120.012
negative regulation of developmental processGO:00510932010.012
dna endoreduplicationGO:0042023220.012
regulation of notch signaling pathwayGO:00085931000.012
tube morphogenesisGO:00352391910.012
regulation of phosphate metabolic processGO:00192202100.012
purine ribonucleoside catabolic processGO:00461301120.012
chemosensory behaviorGO:00076351060.012
purine containing compound catabolic processGO:00725231120.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
enzyme linked receptor protein signaling pathwayGO:00071671790.012
positive regulation of catalytic activityGO:00430851180.012
rna polyadenylationGO:0043631120.012
positive regulation of molecular functionGO:00440931360.012
negative regulation of nucleobase containing compound metabolic processGO:00459342610.012
protein phosphorylationGO:00064681690.012
mrna polyadenylationGO:0006378110.012
embryonic development via the syncytial blastodermGO:00017001480.012
protein processingGO:0016485680.012
defense response to gram negative bacteriumGO:0050829940.012
negative regulation of organelle organizationGO:0010639560.012
Human
eye photoreceptor cell differentiationGO:00017541450.012
organonitrogen compound biosynthetic processGO:19015661170.012
single organism biosynthetic processGO:00447112060.012
metal ion transportGO:0030001740.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
Human
chemotaxisGO:00069352490.012
dorsal ventral pattern formationGO:00099531330.012
dendrite developmentGO:00163582040.012
double strand break repairGO:0006302260.012
regulation of anatomical structure morphogenesisGO:00226032420.012
single organism membrane organizationGO:0044802930.012
dna packagingGO:0006323910.012
dna damage checkpointGO:0000077780.011
dna integrity checkpointGO:0031570810.011
olfactory behaviorGO:0042048970.011
cellular response to chemical stimulusGO:00708871990.011
nucleobase containing small molecule metabolic processGO:00550861740.011
positive regulation of hydrolase activityGO:0051345780.011
negative regulation of cell communicationGO:00106482230.011
chromatin organizationGO:00063252070.011
forebrain developmentGO:003090020.011
ion transmembrane transportGO:00342201220.011
regulation of defense responseGO:00313471020.011
columnar cuboidal epithelial cell differentiationGO:00020652560.011
negative regulation of cellular protein metabolic processGO:0032269850.011
Human
digestive tract developmentGO:00485651490.011
nucleotide metabolic processGO:00091171610.011
negative regulation of rna biosynthetic processGO:19026792400.011
positive regulation of phosphorus metabolic processGO:00105621390.011
cellular macromolecular complex assemblyGO:00346221530.011
ribonucleoside metabolic processGO:00091191270.011
metaphase anaphase transition of cell cycleGO:0044784280.011
actin filament based processGO:00300292200.011
nucleoside catabolic processGO:00091641120.011
ribonucleotide catabolic processGO:00092611090.011
organophosphate catabolic processGO:00464341120.011
negative regulation of homeostatic processGO:003284520.011
chaeta developmentGO:0022416970.011
gland developmentGO:00487321910.011
response to monosaccharideGO:003428440.011
purine nucleotide catabolic processGO:00061951090.011
regulation of proteolysisGO:0030162870.011
Human
intracellular protein transportGO:00068861040.011
histolysisGO:00075591020.011
regionalizationGO:00030024160.011
tube developmentGO:00352952440.011
cytokinesisGO:0000910900.011
nephron developmentGO:007200630.011
acylglycerol catabolic processGO:004646430.011
defense response to bacteriumGO:00427421780.011
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.011
response to oxygen containing compoundGO:19017002000.011
camera type eye morphogenesisGO:004859320.011
establishment of protein localizationGO:00451841630.011
cellular response to biotic stimulusGO:007121640.011
wound healingGO:0042060750.011
regulation of apoptotic processGO:00429811300.010
nucleoside metabolic processGO:00091161270.010
ribonucleoside triphosphate catabolic processGO:00092031080.010
positive regulation of cell migrationGO:003033520.010
nuclear transportGO:0051169720.010
defense responseGO:00069523000.010
response to light stimulusGO:00094161240.010
cell migrationGO:00164772380.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
regulation of cell deathGO:00109411730.010
regulation of immune responseGO:00507761180.010
protein maturationGO:0051604710.010
purine ribonucleotide catabolic processGO:00091541090.010
regulation of mitotic metaphase anaphase transitionGO:0030071260.010
Human
response to bacteriumGO:00096171980.010
positive regulation of catabolic processGO:00098961050.010
protein dna complex assemblyGO:0065004630.010
peptidyl amino acid modificationGO:00181931050.010
actin filament organizationGO:00070151260.010
skeletal muscle fiber developmentGO:004874130.010
multicellular organismal reproductive behaviorGO:00330571100.010

Gen disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.059
disease of metabolismDOID:001466700.017
inherited metabolic disorderDOID:65500.016
nervous system diseaseDOID:86300.015
respiratory system diseaseDOID:157900.014
lower respiratory tract diseaseDOID:005016100.014
cardiovascular system diseaseDOID:128700.013