Drosophila melanogaster

51 known processes

Tpi (Dmel_CG2171)

Triose phosphate isomerase

(Aliases: ND14,wstd,CG2171,Dmel\CG2171,TPI,TPIS,sgk,tpi)

Tpi biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
myoblast fusionGO:0007520430.988
agingGO:00075681430.929
syncytium formation by plasma membrane fusionGO:0000768430.877
paracrine signalingGO:003800170.851
organonitrogen compound metabolic processGO:19015643180.798
syncytium formationGO:0006949430.779
response to oxygen radicalGO:000030530.744
response to organic substanceGO:00100332840.740
response to oxidative stressGO:0006979860.731
response to abiotic stimulusGO:00096283410.715
muscle cell differentiationGO:00426921030.673
oxidation reduction processGO:00551141230.668
small molecule metabolic processGO:00442813050.629
acetaldehyde metabolic processGO:000611750.550
age dependent general metabolic declineGO:000757130.511
myotube differentiationGO:0014902460.505
response to hydrogen peroxideGO:0042542110.488
purine nucleoside metabolic processGO:00422781270.419
response to superoxideGO:000030330.415
single organism biosynthetic processGO:00447112060.397
defense responseGO:00069523000.391
response to metal ionGO:0010038230.386
age dependent response to oxidative stressGO:000130630.375
pyruvate metabolic processGO:000609070.353
determination of adult lifespanGO:00083401370.351
oxoacid metabolic processGO:00434361030.347
nucleobase containing small molecule metabolic processGO:00550861740.335
muscle structure developmentGO:00610612240.315
response to oxygen containing compoundGO:19017002000.311
response to extracellular stimulusGO:00099911160.286
striated muscle cell differentiationGO:0051146900.259
carboxylic acid metabolic processGO:0019752920.250
multicellular organismal agingGO:00102591400.250
ribonucleoside biosynthetic processGO:004245530.237
nucleoside metabolic processGO:00091161270.236
hydrogen peroxide catabolic processGO:004274460.230
immune system processGO:00023763470.220
organic hydroxy compound metabolic processGO:1901615830.217
organonitrogen compound biosynthetic processGO:19015661170.208
response to reactive oxygen speciesGO:0000302240.205
regulation of programmed cell deathGO:00430671520.203
purine containing compound metabolic processGO:00725211550.199
response to heatGO:0009408630.191
single organism behaviorGO:00447083910.188
lipid metabolic processGO:00066291210.183
response to inorganic substanceGO:0010035440.177
cellular response to chemical stimulusGO:00708871990.174
deathGO:00162652840.164
organophosphate metabolic processGO:00196371950.162
Mouse
somatic muscle developmentGO:0007525660.159
response to organophosphorusGO:004668320.157
generation of precursor metabolites and energyGO:0006091420.155
purine ribonucleoside metabolic processGO:00461281270.154
organic acid metabolic processGO:00060821030.153
ribonucleoside triphosphate metabolic processGO:00091991190.151
response to nitrogen compoundGO:1901698900.146
regulation of cellular response to oxidative stressGO:190040740.146
carbohydrate derivative metabolic processGO:19011352170.142
Mouse
negative regulation of biosynthetic processGO:00098902770.141
response to external biotic stimulusGO:00432072930.139
response to other organismGO:00517072930.134
oxidative phosphorylationGO:000611990.129
organic substance catabolic processGO:19015753080.128
immune responseGO:00069552460.124
spermatogenesisGO:00072832000.123
atp biosynthetic processGO:000675420.120
catabolic processGO:00090564090.119
organophosphate biosynthetic processGO:0090407460.118
energy derivation by oxidation of organic compoundsGO:0015980320.118
glycosyl compound metabolic processGO:19016571270.117
cellular lipid metabolic processGO:0044255830.115
nucleoside phosphate metabolic processGO:00067531620.107
ribose phosphate metabolic processGO:00196931450.104
response to organonitrogen compoundGO:0010243750.103
response to starvationGO:0042594970.100
purine ribonucleoside triphosphate metabolic processGO:00092051190.100
peptide metabolic processGO:0006518800.099
positive regulation of transcription dna templatedGO:00458932660.098
innate immune responseGO:00450871440.097
negative regulation of multicellular organismal processGO:00512411420.096
response to oxygen levelsGO:0070482590.095
cellular response to salt stressGO:007147210.095
cell deathGO:00082192790.094
cell agingGO:000756920.093
cellular response to reactive oxygen speciesGO:0034614140.093
response to endogenous stimulusGO:00097191190.092
ribonucleoside metabolic processGO:00091191270.091
cellular amino acid metabolic processGO:0006520610.090
apoptotic processGO:00069151590.089
response to nutrient levelsGO:00316671140.086
nucleotide metabolic processGO:00091171610.085
monocarboxylic acid metabolic processGO:0032787290.083
cellular component assembly involved in morphogenesisGO:00109271510.083
Worm
single organism catabolic processGO:00447122280.083
cellular response to superoxideGO:007145130.083
cellular response to starvationGO:0009267610.083
cellular response to dna damage stimulusGO:00069742230.082
response to bacteriumGO:00096171980.081
atp metabolic processGO:0046034490.079
cellular response to arsenic containing substanceGO:007124360.079
positive regulation of reactive oxygen species metabolic processGO:200037900.077
nad metabolic processGO:001967410.076
nicotinamide nucleotide metabolic processGO:004649620.074
response to woundingGO:0009611940.073
carbohydrate catabolic processGO:001605270.073
purine nucleoside triphosphate metabolic processGO:00091441190.072
intracellular signal transductionGO:00355563000.071
purine nucleoside biosynthetic processGO:004245130.067
response to organic cyclic compoundGO:0014070890.065
cellular response to oxidative stressGO:0034599280.062
response to ethanolGO:0045471590.061
response to hexoseGO:000974630.060
regulation of response to oxidative stressGO:190288240.060
programmed cell deathGO:00125012570.059
cellular catabolic processGO:00442483720.059
single organism carbohydrate metabolic processGO:0044723720.058
cellular macromolecular complex assemblyGO:00346221530.056
Worm
ribonucleoside triphosphate biosynthetic processGO:000920120.055
purine ribonucleoside triphosphate biosynthetic processGO:000920620.055
positive regulation of cell deathGO:0010942690.054
epithelial cell differentiationGO:00308553220.053
response to osmotic stressGO:0006970140.053
phosphorylationGO:00163102940.052
glycolytic processGO:000609660.052
response to temperature stimulusGO:00092661060.052
regulation of anatomical structure sizeGO:00900661630.052
dorsal appendage formationGO:0046843470.052
purine nucleotide metabolic processGO:00061631460.051
response to transition metal nanoparticleGO:199026790.051
regulation of cellular catabolic processGO:00313291570.051
ribonucleotide catabolic processGO:00092611090.050
glycosyl compound biosynthetic processGO:190165930.049
protein complex assemblyGO:00064612000.049
Worm
endocytosisGO:00068973100.049
regulation of immune system processGO:00026821760.048
behavioral response to ethanolGO:0048149490.048
response to biotic stimulusGO:00096072940.048
regulation of apoptotic processGO:00429811300.047
positive regulation of response to stimulusGO:00485843230.046
maintenance of locationGO:0051235730.046
purine ribonucleoside monophosphate metabolic processGO:0009167500.046
nucleoside biosynthetic processGO:000916330.046
carbohydrate derivative biosynthetic processGO:1901137850.045
purine ribonucleotide metabolic processGO:00091501450.045
cellular protein complex assemblyGO:0043623710.044
Worm
cellular modified amino acid metabolic processGO:0006575450.043
ribonucleotide metabolic processGO:00092591450.043
spermatid differentiationGO:00485151140.043
purine nucleoside monophosphate metabolic processGO:0009126500.041
posttranscriptional regulation of gene expressionGO:00106081450.041
positive regulation of programmed cell deathGO:0043068620.041
inorganic ion transmembrane transportGO:0098660730.040
regulation of multicellular organismal developmentGO:20000264140.040
cellular response to metal ionGO:007124860.039
macromolecular complex assemblyGO:00650032560.039
Worm
adult locomotory behaviorGO:0008344760.039
cellular respirationGO:0045333260.039
purine containing compound catabolic processGO:00725231120.039
respiratory electron transport chainGO:0022904110.038
purine nucleoside monophosphate biosynthetic processGO:000912730.038
nucleoside phosphate biosynthetic processGO:1901293340.038
regulation of cell deathGO:00109411730.038
cellular response to organic substanceGO:00713101320.037
cellular response to hormone stimulusGO:0032870440.037
negative regulation of programmed cell deathGO:0043069720.036
epithelial cell developmentGO:00020642740.036
organonitrogen compound catabolic processGO:19015651280.034
ribonucleoside monophosphate metabolic processGO:0009161510.034
nucleoside monophosphate metabolic processGO:0009123520.034
regulation of intracellular signal transductionGO:19025312360.034
regulation of catabolic processGO:00098941700.033
sulfur compound metabolic processGO:0006790590.033
inorganic cation transmembrane transportGO:0098662610.033
purine ribonucleoside monophosphate biosynthetic processGO:000916830.031
organophosphate catabolic processGO:00464341120.030
mitochondrion organizationGO:0007005650.030
cellular response to extracellular stimulusGO:0031668640.030
response to glucoseGO:000974920.029
cellular response to external stimulusGO:0071496660.029
negative regulation of cell cycleGO:00457861160.029
ion transportGO:00068111450.028
striated muscle myosin thick filament assemblyGO:007168830.028
Worm
purine ribonucleoside biosynthetic processGO:004612930.028
pyridine containing compound metabolic processGO:007252430.028
localization of cellGO:00516742570.027
carbohydrate metabolic processGO:0005975820.027
larval developmentGO:00021641040.027
cellular response to nutrient levelsGO:0031669620.027
male gamete generationGO:00482322010.026
regulation of myotube differentiationGO:001083060.026
homeostatic processGO:00425921990.025
Worm
glucose metabolic processGO:000600650.025
Mouse
regulation of cellular amine metabolic processGO:003323830.024
regulation of gtpase activityGO:0043087440.024
ribose phosphate biosynthetic processGO:0046390280.024
response to hyperoxiaGO:005509330.024
small molecule biosynthetic processGO:0044283370.024
electron transport chainGO:0022900140.024
nucleoside triphosphate metabolic processGO:00091411200.024
cellular response to oxygen containing compoundGO:1901701790.024
cellular nitrogen compound catabolic processGO:00442701650.023
protein complex biogenesisGO:00702712010.023
Worm
cation transmembrane transportGO:0098655880.023
regulation of cellular protein metabolic processGO:00322682430.022
cellular ketone metabolic processGO:0042180240.022
signal transduction by phosphorylationGO:00230141070.022
positive regulation of cellular biosynthetic processGO:00313283160.022
regulation of anatomical structure morphogenesisGO:00226032420.022
purine ribonucleotide catabolic processGO:00091541090.022
regulation of phosphate metabolic processGO:00192202100.022
appendage morphogenesisGO:00351073970.022
purine ribonucleoside catabolic processGO:00461301120.022
regulation of cell developmentGO:00602842150.021
spermatid developmentGO:0007286980.021
positive regulation of biosynthetic processGO:00098913160.021
macromolecule catabolic processGO:00090571610.020
nucleobase containing compound catabolic processGO:00346551650.020
purine ribonucleoside triphosphate catabolic processGO:00092071080.020
negative regulation of developmental processGO:00510932010.020
negative regulation of apoptotic processGO:0043066630.020
heart developmentGO:0007507820.019
vesicle mediated transportGO:00161923810.019
positive regulation of macromolecule metabolic processGO:00106044050.019
positive regulation of cell motilityGO:200014730.019
defense response to gram negative bacteriumGO:0050829940.019
regulation of nitric oxide biosynthetic processGO:004542810.019
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.019
oxidoreduction coenzyme metabolic processGO:000673320.019
cellular amide metabolic processGO:0043603800.019
metal ion homeostasisGO:0055065440.019
regulation of mapk cascadeGO:0043408920.018
cuticle developmentGO:0042335860.018
alcohol metabolic processGO:0006066250.018
transcription from rna polymerase ii promoterGO:00063663680.018
heart morphogenesisGO:0003007320.018
circulatory system processGO:0003013370.018
ribonucleoside catabolic processGO:00424541120.018
carbohydrate derivative catabolic processGO:19011361180.017
nucleoside catabolic processGO:00091641120.017
glutathione metabolic processGO:0006749370.017
forebrain developmentGO:003090020.017
negative regulation of cellular biosynthetic processGO:00313272770.017
cell adhesionGO:00071551360.017
negative regulation of signalingGO:00230572190.017
negative regulation of cell deathGO:0060548810.017
response to salt stressGO:0009651110.017
regulation of cellular component sizeGO:0032535980.017
regulation of lipid metabolic processGO:0019216150.017
regulation of purine nucleotide metabolic processGO:1900542620.017
monovalent inorganic cation transportGO:0015672400.017
response to hypoxiaGO:0001666530.017
regulation of response to stressGO:00801342000.016
phagocytosisGO:00069092150.016
lipid biosynthetic processGO:0008610460.016
enzyme linked receptor protein signaling pathwayGO:00071671790.016
actin filament based processGO:00300292200.016
Worm
heterocycle catabolic processGO:00467001660.016
positive regulation of phosphorus metabolic processGO:00105621390.016
response to decreased oxygen levelsGO:0036293580.016
regulation of dna templated transcription in response to stressGO:004362040.016
ribonucleoside triphosphate catabolic processGO:00092031080.016
purine nucleotide biosynthetic processGO:0006164290.015
cell type specific apoptotic processGO:0097285380.015
cellular response to insulin stimulusGO:0032869280.015
wing disc morphogenesisGO:00074723440.015
regulation of mitochondrion organizationGO:0010821120.015
regulation of catalytic activityGO:00507901850.015
cellular homeostasisGO:0019725800.015
Worm
purine nucleotide catabolic processGO:00061951090.015
regulation of nucleotide catabolic processGO:0030811480.015
glycerolipid metabolic processGO:0046486340.015
response to light stimulusGO:00094161240.015
positive regulation of intracellular signal transductionGO:19025331160.015
response to hormoneGO:0009725450.014
plasma membrane organizationGO:0007009260.014
nucleoside triphosphate catabolic processGO:00091431080.014
glucan biosynthetic processGO:000925020.014
heart processGO:0003015370.014
imaginal disc derived wing morphogenesisGO:00074763370.014
regulation of cell differentiationGO:00455953020.014
positive regulation of immune system processGO:0002684680.014
regulation of immune responseGO:00507761180.014
positive regulation of molecular functionGO:00440931360.014
sex differentiationGO:0007548810.014
cell migrationGO:00164772380.013
regulation of nucleoside metabolic processGO:0009118500.013
positive regulation of nitrogen compound metabolic processGO:00511733540.013
mitochondrial atp synthesis coupled electron transportGO:004277580.013
positive regulation of cell communicationGO:00106472500.013
positive regulation of nucleoside metabolic processGO:0045979470.013
positive regulation of nitric oxide biosynthetic processGO:004542910.013
developmental growthGO:00485892800.013
sterol metabolic processGO:0016125120.013
cellular aldehyde metabolic processGO:0006081100.013
Mouse
negative regulation of cell differentiationGO:00455961430.013
regulation of protein metabolic processGO:00512462560.013
aromatic compound catabolic processGO:00194391660.013
synaptic transmissionGO:00072682880.013
cellular response to peptide hormone stimulusGO:0071375280.012
alcohol biosynthetic processGO:0046165140.012
ribonucleotide biosynthetic processGO:0009260280.012
atp synthesis coupled electron transportGO:004277380.012
lipid storageGO:0019915380.012
cellular amine metabolic processGO:0044106120.012
negative regulation of protein metabolic processGO:0051248850.012
imaginal disc derived appendage developmentGO:00487373990.012
regulation of signal transduction by p53 class mediatorGO:190179610.012
cell motilityGO:00488702510.012
purine ribonucleotide biosynthetic processGO:0009152280.012
positive regulation of signal transductionGO:00099672230.012
nucleoside phosphate catabolic processGO:19012921100.012
regionalizationGO:00030024160.011
positive regulation of mapk cascadeGO:0043410630.011
carboxylic acid transportGO:0046942180.011
neuron deathGO:0070997270.011
negative regulation of macromolecule biosynthetic processGO:00105582700.011
cellular response to endogenous stimulusGO:0071495800.011
anion transportGO:0006820410.011
negative regulation of cellular component organizationGO:00511291080.011
proteolysisGO:00065081920.011
negative regulation of lipid metabolic processGO:004583330.011
wound healingGO:0042060750.011
locomotory behaviorGO:00076261760.011
response to toxic substanceGO:0009636220.011
regulation of organelle organizationGO:00330431960.011
immune response activating signal transductionGO:000275720.011
response to lipidGO:0033993380.011
alcohol catabolic processGO:004616440.011
response to monosaccharideGO:003428440.011
organic hydroxy compound catabolic processGO:190161640.011
positive regulation of catalytic activityGO:00430851180.010
regulation of phosphorus metabolic processGO:00511742100.010
positive regulation of catabolic processGO:00098961050.010
defense response to bacteriumGO:00427421780.010
regulation of hydrolase activityGO:0051336970.010
cell proliferationGO:00082832990.010
cellular biogenic amine catabolic processGO:004240210.010
negative regulation of organelle organizationGO:0010639560.010
response to lipopolysaccharideGO:003249640.010
regulation of cell morphogenesisGO:00226041630.010

Tpi disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.364
nervous system diseaseDOID:86300.020
organ system cancerDOID:005068600.014
cancerDOID:16200.014
disease of cellular proliferationDOID:1456600.014
anemiaDOID:235500.014
immune system diseaseDOID:291400.014
hematopoietic system diseaseDOID:7400.014
neurodegenerative diseaseDOID:128900.013
central nervous system diseaseDOID:33100.013