IMP: Integrative Multi-species Prediction

Drosophila melanogaster

165 known processes

rap (Dmel_CG3000)

retina aberrant in pattern

(Aliases: Cdh1/Fzr,Fzr,Dmel\CG3000,Fxr,Rap/Fzr,rap/Fzr,anon-WO03040301.193,Cdh[Fzr],fzr,Cdh1,wex,APC/C[Fzr/Cdh1],CDH1,l(1)G0326,cdh1,rap/fzr,Hec/Cdh[Fzr],l(1)G0418,CG3000,dFZR,Cdh1[Fzr],rap/fizzy-related)

Entrez: 45922
FLYBASE: FBgn0003200
UniProtKB: Q9W4H9

Process Predictions
Disease Predictions

rap biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
axon development	GO:0061564	297	0.978
cellular protein modification process	GO:0006464	438	0.964
axonogenesis	GO:0007409	290	0.960
programmed cell death	GO:0012501	257	0.922
protein modification process	GO:0036211	438	0.917
regulation of cellular catabolic process	GO:0031329	157	0.886
neuron projection guidance	GO:0097485	241	0.883
cell motility	GO:0048870	251	0.877
tube development	GO:0035295	244	0.872
regulation of intracellular signal transduction	GO:1902531	236	0.857
positive regulation of gliogenesis	GO:0014015	5	0.844
negative regulation of cellular metabolic process	GO:0031324	382	0.811
regulation of multicellular organismal development	GO:2000026	414	0.803
hematopoietic or lymphoid organ development	GO:0048534	57	0.792
phosphorylation	GO:0016310	294	0.774
tracheal outgrowth open tracheal system	GO:0007426	18	0.769
cell death	GO:0008219	279	0.765
death	GO:0016265	284	0.747
regulation of phosphorylation	GO:0042325	147	0.743
peripheral nervous system development	GO:0007422	52	0.740
positive regulation of protein metabolic process	GO:0051247	128	0.738
ras protein signal transduction	GO:0007265	88	0.730
intracellular signal transduction	GO:0035556	300	0.717
hemopoiesis	GO:0030097	46	0.710
regulation of cell cycle	GO:0051726	291	0.695
cell fate specification	GO:0001708	71	0.687
stem cell fate commitment	GO:0048865	25	0.681
stem cell proliferation	GO:0072089	88	0.677
immune system development	GO:0002520	57	0.669
sensory organ precursor cell division	GO:0045035	10	0.668
embryonic organ development	GO:0048568	50	0.667
cellular catabolic process	GO:0044248	372	0.655
muscle cell differentiation	GO:0042692	103	0.653
regulation of phosphate metabolic process	GO:0019220	210	0.636
digestive system development	GO:0055123	149	0.633
gland development	GO:0048732	191	0.621
neuron fate commitment	GO:0048663	50	0.604
regulation of cell death	GO:0010941	173	0.601
response to organic substance	GO:0010033	284	0.571
cell fate determination	GO:0001709	91	0.566
protein phosphorylation	GO:0006468	169	0.565
regulation of programmed cell death	GO:0043067	152	0.546
regulation of protein modification process	GO:0031399	112	0.539
small molecule metabolic process	GO:0044281	305	0.538
negative regulation of rna metabolic process	GO:0051253	251	0.537
exocrine system development	GO:0035272	162	0.535
somatic stem cell maintenance	GO:0035019	14	0.524
photoreceptor cell differentiation	GO:0046530	170	0.519
morphogenesis of an epithelium	GO:0002009	276	0.515
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.509
tube morphogenesis	GO:0035239	191	0.490
chemotaxis	GO:0006935	249	0.485
developmental programmed cell death	GO:0010623	138	0.484
neuroblast fate commitment	GO:0014017	19	0.484
cell migration	GO:0016477	238	0.478
protein modification by small protein conjugation or removal	GO:0070647	106	0.473
cardiocyte differentiation	GO:0035051	29	0.471
stem cell differentiation	GO:0048863	117	0.468
epithelial cell differentiation	GO:0030855	322	0.467	Mouse
regulation of cellular localization	GO:0060341	136	0.465
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.449
locomotory behavior	GO:0007626	176	0.449
negative regulation of gene expression	GO:0010629	387	0.443
negative regulation of cell differentiation	GO:0045596	143	0.441
positive regulation of macromolecule metabolic process	GO:0010604	405	0.440
cellular response to organic substance	GO:0071310	132	0.439
synaptic growth at neuromuscular junction	GO:0051124	119	0.439
regulation of phosphorus metabolic process	GO:0051174	210	0.431
negative regulation of cell death	GO:0060548	81	0.428
reproductive behavior	GO:0019098	122	0.421	Worm
positive regulation of cellular protein metabolic process	GO:0032270	118	0.415
regulation of immune system process	GO:0002682	176	0.414
regulation of organ morphogenesis	GO:2000027	78	0.410
embryonic pattern specification	GO:0009880	174	0.407
regulation of cell cycle phase transition	GO:1901987	130	0.406
establishment of localization in cell	GO:0051649	402	0.402
circulatory system development	GO:0072359	82	0.397
heart development	GO:0007507	82	0.396
wing disc morphogenesis	GO:0007472	344	0.394
negative regulation of phosphate metabolic process	GO:0045936	45	0.392
regulation of neuron differentiation	GO:0045664	103	0.391
positive regulation of cellular component organization	GO:0051130	156	0.390
digestive tract development	GO:0048565	149	0.378
regulation of apoptotic process	GO:0042981	130	0.364
response to nitrogen compound	GO:1901698	90	0.362
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.355
cellular macromolecule localization	GO:0070727	220	0.355
apoptotic process	GO:0006915	159	0.354
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.352
embryo development ending in birth or egg hatching	GO:0009792	152	0.341	Worm
taxis	GO:0042330	304	0.339
r7 cell differentiation	GO:0045466	43	0.337
positive regulation of neurogenesis	GO:0050769	41	0.326
cell proliferation	GO:0008283	299	0.326	Mouse
negative regulation of programmed cell death	GO:0043069	72	0.325
protein modification by small protein conjugation	GO:0032446	79	0.325
positive regulation of molecular function	GO:0044093	136	0.324
regulation of molecular function	GO:0065009	217	0.318
dendrite morphogenesis	GO:0048813	199	0.314
regulation of cell cycle process	GO:0010564	181	0.312
regulation of mitotic cell cycle	GO:0007346	190	0.309
regulation of catabolic process	GO:0009894	170	0.305
positive regulation of nervous system development	GO:0051962	69	0.297
catabolic process	GO:0009056	409	0.297
malpighian tubule development	GO:0072002	64	0.295
renal system development	GO:0072001	72	0.290
head development	GO:0060322	135	0.281
regulation of small gtpase mediated signal transduction	GO:0051056	93	0.268
positive regulation of catabolic process	GO:0009896	105	0.260
regulation of transport	GO:0051049	181	0.259
asymmetric cell division	GO:0008356	37	0.259
gland morphogenesis	GO:0022612	145	0.258
compound eye photoreceptor fate commitment	GO:0001752	36	0.257
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.257
regulation of actin filament polymerization	GO:0030833	25	0.253
nuclear division	GO:0000280	332	0.252
segmentation	GO:0035282	207	0.251
regulation of glial cell proliferation	GO:0060251	11	0.247
muscle organ development	GO:0007517	127	0.247
developmental growth	GO:0048589	280	0.243
cognition	GO:0050890	141	0.242
photoreceptor cell fate commitment	GO:0046552	41	0.236
immune system process	GO:0002376	347	0.236
protein complex assembly	GO:0006461	200	0.235
regulation of dna metabolic process	GO:0051052	34	0.233
localization of cell	GO:0051674	257	0.229
mitotic nuclear division	GO:0007067	213	0.228
regulation of cell proliferation	GO:0042127	163	0.226	Mouse
proteolysis	GO:0006508	192	0.222
organelle fission	GO:0048285	340	0.218
single organism behavior	GO:0044708	391	0.217
negative regulation of cellular protein metabolic process	GO:0032269	85	0.217
negative regulation of phosphorylation	GO:0042326	35	0.217
stem cell development	GO:0048864	79	0.216
positive regulation of multicellular organismal process	GO:0051240	143	0.212
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.211
response to abiotic stimulus	GO:0009628	341	0.205
positive regulation of organelle organization	GO:0010638	65	0.205
digestive tract morphogenesis	GO:0048546	127	0.204
regulation of proteasomal ubiquitin dependent protein catabolic process	GO:0032434	37	0.204
cellular response to chemical stimulus	GO:0070887	199	0.204
mitotic cell cycle embryonic	GO:0045448	38	0.203
autophagy	GO:0006914	108	0.201
positive regulation of protein modification process	GO:0031401	58	0.200
formation of organ boundary	GO:0010160	30	0.198
regulation of catalytic activity	GO:0050790	185	0.198
regulation of neurogenesis	GO:0050767	158	0.194
regulation of cell development	GO:0060284	215	0.193
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.192
dendrite development	GO:0016358	204	0.192
mesenchymal cell differentiation	GO:0048762	1	0.191
macromolecular complex assembly	GO:0065003	256	0.190
cell cycle comprising mitosis without cytokinesis	GO:0033301	25	0.189
positive regulation of rna metabolic process	GO:0051254	271	0.188
intracellular transport	GO:0046907	228	0.186
vesicle mediated transport	GO:0016192	381	0.185
regulation of cell cycle g1 s phase transition	GO:1902806	23	0.185
appendage development	GO:0048736	401	0.183
positive regulation of nucleoside metabolic process	GO:0045979	47	0.180
instar larval development	GO:0002168	55	0.179
learning or memory	GO:0007611	141	0.179
small gtpase mediated signal transduction	GO:0007264	88	0.177
chaeta development	GO:0022416	97	0.176
muscle structure development	GO:0061061	224	0.175
organic substance catabolic process	GO:1901575	308	0.171
negative regulation of cell communication	GO:0010648	223	0.171
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.169
muscle cell development	GO:0055001	50	0.169
response to external biotic stimulus	GO:0043207	293	0.168
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.167
regulation of cellular component biogenesis	GO:0044087	201	0.167
regulation of dendrite development	GO:0050773	37	0.166
salivary gland morphogenesis	GO:0007435	145	0.166
mesenchymal cell development	GO:0014031	1	0.166
organelle localization	GO:0051640	148	0.164
cell cycle g1 s phase transition	GO:0044843	31	0.164
regulation of protein metabolic process	GO:0051246	256	0.164
developmental maturation	GO:0021700	172	0.163
regulation of growth	GO:0040008	233	0.162
negative regulation of signal transduction	GO:0009968	206	0.162
striated muscle cell differentiation	GO:0051146	90	0.161
positive regulation of biosynthetic process	GO:0009891	316	0.160
regulation of stem cell proliferation	GO:0072091	40	0.160
response to oxygen containing compound	GO:1901700	200	0.158
retinal ganglion cell axon guidance	GO:0031290	12	0.157
blastoderm segmentation	GO:0007350	159	0.157
mushroom body development	GO:0016319	70	0.153
camera type eye morphogenesis	GO:0048593	2	0.153
negative regulation of apoptotic process	GO:0043066	63	0.153
positive regulation of cellular biosynthetic process	GO:0031328	316	0.152
peptidyl amino acid modification	GO:0018193	105	0.146
protein localization	GO:0008104	284	0.146
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.145
response to endogenous stimulus	GO:0009719	119	0.144
protein transport	GO:0015031	155	0.139
negative regulation of synapse assembly	GO:0051964	39	0.138
axon guidance	GO:0007411	233	0.138
regulation of kinase activity	GO:0043549	53	0.138
modification dependent protein catabolic process	GO:0019941	78	0.137
endocytosis	GO:0006897	310	0.134
response to hormone	GO:0009725	45	0.132
body morphogenesis	GO:0010171	2	0.130
meiosis i	GO:0007127	59	0.130
renal tubule development	GO:0061326	64	0.129
morphogenesis of embryonic epithelium	GO:0016331	94	0.129
lipid localization	GO:0010876	54	0.128
stem cell division	GO:0017145	69	0.127
sister chromatid segregation	GO:0000819	92	0.127
phagocytosis	GO:0006909	215	0.126
oocyte maturation	GO:0001556	3	0.125
muscle tissue morphogenesis	GO:0060415	2	0.125
malpighian tubule tip cell differentiation	GO:0061382	9	0.125
regulation of cell fate specification	GO:0042659	27	0.125
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.125
negative regulation of protein modification process	GO:0031400	29	0.125
regulation of anatomical structure morphogenesis	GO:0022603	242	0.123
positive regulation of transcription dna templated	GO:0045893	266	0.123
compound eye morphogenesis	GO:0001745	249	0.122
positive regulation of developmental process	GO:0051094	143	0.122
negative regulation of cellular biosynthetic process	GO:0031327	277	0.122
chromosome segregation	GO:0007059	157	0.122
imaginal disc derived wing morphogenesis	GO:0007476	337	0.121
negative regulation of protein metabolic process	GO:0051248	85	0.121
neuron remodeling	GO:0016322	29	0.120
urogenital system development	GO:0001655	72	0.119
negative regulation of rna biosynthetic process	GO:1902679	240	0.119
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.118
compound eye development	GO:0048749	307	0.117
axis specification	GO:0009798	167	0.116
positive regulation of gene expression	GO:0010628	290	0.116
central nervous system neuron differentiation	GO:0021953	8	0.116
mesoderm development	GO:0007498	78	0.113
telencephalon development	GO:0021537	2	0.112
positive regulation of epithelial cell differentiation	GO:0030858	1	0.111
regulation of photoreceptor cell differentiation	GO:0046532	34	0.110
negative regulation of phosphorus metabolic process	GO:0010563	45	0.110
regulation of gene expression epigenetic	GO:0040029	128	0.110
notch signaling pathway	GO:0007219	120	0.109
eye photoreceptor cell differentiation	GO:0001754	145	0.108
g1 s transition of mitotic cell cycle	GO:0000082	31	0.106
regulation of epithelial cell proliferation	GO:0050678	4	0.104
nucleocytoplasmic transport	GO:0006913	72	0.102
cell cycle checkpoint	GO:0000075	95	0.102
negative regulation of mitotic cell cycle	GO:0045930	109	0.102
positive regulation of transport	GO:0051050	92	0.101
tissue morphogenesis	GO:0048729	297	0.101
cell adhesion	GO:0007155	136	0.101
regulation of protein kinase activity	GO:0045859	51	0.101
learning	GO:0007612	75	0.100
actin filament polymerization	GO:0030041	27	0.100
regulation of actin polymerization or depolymerization	GO:0008064	27	0.100
compound eye photoreceptor cell differentiation	GO:0001751	140	0.099
immune effector process	GO:0002252	98	0.098
regulation of cellular protein metabolic process	GO:0032268	243	0.098
activation of ras gtpase activity	GO:0032856	6	0.098
immune response	GO:0006955	246	0.097
reproductive system development	GO:0061458	74	0.097
epidermal growth factor receptor signaling pathway	GO:0007173	58	0.096
single organism catabolic process	GO:0044712	228	0.095
multi organism reproductive behavior	GO:0044705	121	0.094	Worm
positive regulation of rna biosynthetic process	GO:1902680	266	0.094
chromatin silencing	GO:0006342	76	0.094
gastrulation	GO:0007369	70	0.093
protein complex biogenesis	GO:0070271	201	0.093
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.093
posttranscriptional regulation of gene expression	GO:0010608	145	0.092
hindgut morphogenesis	GO:0007442	58	0.092
epithelial cell migration	GO:0010631	148	0.092
positive regulation of cellular catabolic process	GO:0031331	95	0.091
sex differentiation	GO:0007548	81	0.090
axon midline choice point recognition	GO:0016199	26	0.090
development of primary sexual characteristics	GO:0045137	50	0.088
positive regulation of gtp catabolic process	GO:0033126	43	0.088
organelle assembly	GO:0070925	198	0.088
regulation of pathway restricted smad protein phosphorylation	GO:0060393	1	0.087
response to organonitrogen compound	GO:0010243	75	0.085
secretion by cell	GO:0032940	101	0.085
regulation of notch signaling pathway	GO:0008593	100	0.084
cellular protein localization	GO:0034613	160	0.084
growth	GO:0040007	359	0.083
histone modification	GO:0016570	106	0.083
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.082
eye antennal disc development	GO:0035214	60	0.082
signal transduction by phosphorylation	GO:0023014	107	0.082
glial cell migration	GO:0008347	31	0.082
cell fate commitment involved in formation of primary germ layer	GO:0060795	10	0.082
forebrain development	GO:0030900	2	0.080
r3 r4 cell differentiation	GO:0048056	12	0.080
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.080
ubiquitin dependent protein catabolic process	GO:0006511	78	0.079
regulation of nucleotide catabolic process	GO:0030811	48	0.079
positive regulation of phosphate metabolic process	GO:0045937	139	0.078
appendage morphogenesis	GO:0035107	397	0.078
positive regulation of cell differentiation	GO:0045597	64	0.077
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.077
secretion	GO:0046903	109	0.076
negative regulation of neurogenesis	GO:0050768	53	0.076
sensory organ morphogenesis	GO:0090596	260	0.076
proteasomal protein catabolic process	GO:0010498	59	0.075
connective tissue development	GO:0061448	3	0.075
positive regulation of stem cell proliferation	GO:2000648	8	0.075
cellular protein catabolic process	GO:0044257	83	0.074
negative regulation of signaling	GO:0023057	219	0.074
multi organism behavior	GO:0051705	175	0.073	Worm
positive regulation of axon guidance	GO:1902669	1	0.073
epithelial cell proliferation	GO:0050673	15	0.073
regulation of ras gtpase activity	GO:0032318	38	0.073
cardiovascular system development	GO:0072358	82	0.072
regulation of cell migration	GO:0030334	22	0.072
regulation of protein ubiquitination	GO:0031396	22	0.072
positive regulation of cell migration	GO:0030335	2	0.071
actin polymerization or depolymerization	GO:0008154	31	0.070
substrate dependent cell migration	GO:0006929	3	0.069
border follicle cell migration	GO:0007298	113	0.069
regulation of protein phosphorylation	GO:0001932	64	0.069
positive regulation of hydrolase activity	GO:0051345	78	0.069
spinal cord development	GO:0021510	1	0.069
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.068
carboxylic acid metabolic process	GO:0019752	92	0.068
positive regulation of phosphorylation	GO:0042327	87	0.067
epithelial cell migration open tracheal system	GO:0007427	32	0.067
actin filament bundle assembly	GO:0051017	26	0.066
response to other organism	GO:0051707	293	0.066
mapk cascade	GO:0000165	107	0.066
regulation of gliogenesis	GO:0014013	11	0.065
negative regulation of developmental process	GO:0051093	201	0.065	Mouse
covalent chromatin modification	GO:0016569	106	0.064
negative regulation of transcription dna templated	GO:0045892	237	0.064
cellular macromolecule catabolic process	GO:0044265	136	0.064
maintenance of location	GO:0051235	73	0.064
organophosphate metabolic process	GO:0019637	195	0.064
dorsal closure	GO:0007391	79	0.063
cellular ketone metabolic process	GO:0042180	24	0.063
regulation of cell morphogenesis	GO:0022604	163	0.062
glial cell proliferation	GO:0014009	13	0.062
negative regulation of g1 s transition of mitotic cell cycle	GO:2000134	13	0.062
regulation of erbb signaling pathway	GO:1901184	42	0.060
neuroblast proliferation	GO:0007405	74	0.060
neural precursor cell proliferation	GO:0061351	75	0.060
positive regulation of cell motility	GO:2000147	3	0.060
tissue death	GO:0016271	102	0.060
regulation of protein complex assembly	GO:0043254	42	0.058
positive regulation of immune system process	GO:0002684	68	0.058
positive regulation of cytoskeleton organization	GO:0051495	21	0.058
salivary gland development	GO:0007431	162	0.057
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.057
nucleoside metabolic process	GO:0009116	127	0.057
homeostatic process	GO:0042592	199	0.056
regulation of protein modification by small protein conjugation or removal	GO:1903320	25	0.056
cellular response to endogenous stimulus	GO:0071495	80	0.056
positive regulation of phosphorus metabolic process	GO:0010562	139	0.056
cell cycle phase transition	GO:0044770	140	0.056
positive regulation of cell development	GO:0010720	61	0.055
humoral immune response	GO:0006959	117	0.055
positive regulation of cell communication	GO:0010647	250	0.055
synaptic transmission	GO:0007268	288	0.054
negative regulation of cell proliferation	GO:0008285	69	0.054
regulation of neural precursor cell proliferation	GO:2000177	35	0.054
gene silencing	GO:0016458	138	0.054
endodermal cell fate commitment	GO:0001711	3	0.054
cell junction organization	GO:0034330	57	0.054
endomembrane system organization	GO:0010256	119	0.054
eye morphogenesis	GO:0048592	260	0.054
regulation of actin filament based process	GO:0032970	42	0.054
larval development	GO:0002164	104	0.053
striated muscle cell development	GO:0055002	50	0.053
establishment of protein localization	GO:0045184	163	0.052
proteasome mediated ubiquitin dependent protein catabolic process	GO:0043161	54	0.052
regulation of protein localization	GO:0032880	76	0.052
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.052
neuron maturation	GO:0042551	31	0.051
compound eye cone cell differentiation	GO:0042675	13	0.051
outflow tract morphogenesis	GO:0003151	4	0.051
formation of primary germ layer	GO:0001704	24	0.051
heart morphogenesis	GO:0003007	32	0.051
regulation of cell fate commitment	GO:0010453	29	0.051
reproductive structure development	GO:0048608	74	0.050
compound eye cone cell fate commitment	GO:0042676	5	0.050
meiotic nuclear division	GO:0007126	151	0.050	Mouse Worm
regulation of apoptotic signaling pathway	GO:2001233	10	0.050
response to peptide hormone	GO:0043434	29	0.050
stress activated protein kinase signaling cascade	GO:0031098	55	0.050
hemocyte differentiation	GO:0042386	38	0.049
positive regulation of response to stimulus	GO:0048584	323	0.049
positive regulation of gtpase activity	GO:0043547	43	0.049
positive regulation of cell cycle	GO:0045787	43	0.049
compound eye photoreceptor development	GO:0042051	78	0.048
embryonic hemopoiesis	GO:0035162	26	0.048
regulation of organelle organization	GO:0033043	196	0.048
lipid metabolic process	GO:0006629	121	0.048
cell maturation	GO:0048469	144	0.048
rac protein signal transduction	GO:0016601	3	0.048
regulation of localization	GO:0032879	275	0.048
regulation of protein serine threonine kinase activity	GO:0071900	25	0.047
purine nucleoside catabolic process	GO:0006152	112	0.047
eye antennal disc morphogenesis	GO:0007455	34	0.047
ameboidal type cell migration	GO:0001667	151	0.047
positive regulation of cell cycle process	GO:0090068	28	0.046
actin filament organization	GO:0007015	126	0.046
embryonic heart tube development	GO:0035050	22	0.046
regulation of nucleoside metabolic process	GO:0009118	50	0.046
negative regulation of protein phosphorylation	GO:0001933	17	0.046
spindle organization	GO:0007051	253	0.045
regulation of r7 cell differentiation	GO:0045676	15	0.045
neurological system process	GO:0050877	358	0.045
organonitrogen compound metabolic process	GO:1901564	318	0.045
positive regulation of protein kinase activity	GO:0045860	25	0.045
protein ubiquitination	GO:0016567	70	0.045
positive regulation of signaling	GO:0023056	243	0.045
regulation of neuroblast proliferation	GO:1902692	34	0.045
dna replication	GO:0006260	48	0.044
negative regulation of biosynthetic process	GO:0009890	277	0.044
organic acid metabolic process	GO:0006082	103	0.044
positive regulation of cell proliferation	GO:0008284	47	0.044	Mouse
negative regulation of molecular function	GO:0044092	51	0.044
proteolysis involved in cellular protein catabolic process	GO:0051603	83	0.043
neuron recognition	GO:0008038	101	0.043
hindbrain development	GO:0030902	2	0.043
regulation of cellular component size	GO:0032535	98	0.043
heart field specification	GO:0003128	0	0.043
positive regulation of protein phosphorylation	GO:0001934	34	0.042
transcription from rna polymerase ii promoter	GO:0006366	368	0.042
gtp catabolic process	GO:0006184	72	0.042
response to alcohol	GO:0097305	95	0.041
hematopoietic progenitor cell differentiation	GO:0002244	1	0.041
cardiac cell fate commitment	GO:0060911	17	0.040
histolysis	GO:0007559	102	0.040
germarium derived egg chamber formation	GO:0007293	101	0.040
organic cyclic compound catabolic process	GO:1901361	168	0.040
guanosine containing compound catabolic process	GO:1901069	74	0.040
stress activated mapk cascade	GO:0051403	52	0.040
cardioblast differentiation	GO:0010002	20	0.040
gonad development	GO:0008406	50	0.040
regulation of hydrolase activity	GO:0051336	97	0.039
positive regulation of jun kinase activity	GO:0043507	4	0.039
regulation of nervous system development	GO:0051960	248	0.039
regulation of nucleotide metabolic process	GO:0006140	62	0.039
renal filtration cell differentiation	GO:0061318	12	0.039
eye photoreceptor cell fate commitment	GO:0042706	37	0.039
response to inorganic substance	GO:0010035	44	0.039
cellular amino acid metabolic process	GO:0006520	61	0.039
tissue migration	GO:0090130	155	0.039
developmental growth involved in morphogenesis	GO:0060560	65	0.039
regulation of intracellular transport	GO:0032386	64	0.038
kidney development	GO:0001822	3	0.038
chromatin organization	GO:0006325	207	0.038
defense response to bacterium	GO:0042742	178	0.038
chromatin modification	GO:0016568	147	0.038
positive regulation of signal transduction	GO:0009967	223	0.038
response to lipid	GO:0033993	38	0.038
response to organic cyclic compound	GO:0014070	89	0.038
rho protein signal transduction	GO:0007266	14	0.037
positive regulation of mitotic cell cycle phase transition	GO:1901992	20	0.037
cell cell junction organization	GO:0045216	55	0.037
heterocycle catabolic process	GO:0046700	166	0.037
defense response	GO:0006952	300	0.037
activation of jun kinase activity	GO:0007257	3	0.037
regulation of cytoskeleton organization	GO:0051493	89	0.036
positive regulation of metaphase anaphase transition of cell cycle	GO:1902101	10	0.036
aging	GO:0007568	143	0.036	Mouse
regulation of stem cell differentiation	GO:2000736	14	0.036
planar cell polarity pathway involved in axis elongation	GO:0003402	3	0.036
nucleoside phosphate catabolic process	GO:1901292	110	0.036
regulation of compound eye cone cell fate specification	GO:0042682	4	0.036
morphogenesis of a branching structure	GO:0001763	45	0.036
intracellular protein transport	GO:0006886	104	0.035
regulation of cell differentiation	GO:0045595	302	0.035
response to insulin	GO:0032868	29	0.035
negative regulation of transcription from rna polymerase ii promoter	GO:0000122	119	0.035
organophosphate catabolic process	GO:0046434	112	0.035
oxoacid metabolic process	GO:0043436	103	0.035
regulation of cellular response to stress	GO:0080135	89	0.034
regulation of cellular amine metabolic process	GO:0033238	3	0.034
purine ribonucleotide catabolic process	GO:0009154	109	0.034
regulation of developmental growth	GO:0048638	174	0.034
actomyosin structure organization	GO:0031032	56	0.034
ribonucleotide catabolic process	GO:0009261	109	0.034
meiotic cell cycle	GO:0051321	171	0.033	Mouse Worm
purine nucleotide catabolic process	GO:0006195	109	0.033
regulation of mapk cascade	GO:0043408	92	0.033
regulation of transferase activity	GO:0051338	58	0.033
regulation of jnk cascade	GO:0046328	40	0.033
negative regulation of response to stimulus	GO:0048585	258	0.033
epithelial tube morphogenesis	GO:0060562	88	0.032
regulation of anatomical structure size	GO:0090066	163	0.032
purine ribonucleoside catabolic process	GO:0046130	112	0.032
skin development	GO:0043588	65	0.032
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.032
regionalization	GO:0003002	416	0.031
adherens junction organization	GO:0034332	27	0.031
apoptotic signaling pathway	GO:0097190	27	0.031
cellular response to oxygen containing compound	GO:1901701	79	0.031
positive regulation of cell death	GO:0010942	69	0.031
germ line cyst formation	GO:0048134	44	0.031
photoreceptor cell development	GO:0042461	96	0.031
cellular response to hormone stimulus	GO:0032870	44	0.030

rap disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
cancer	DOID:162	0.189
organ system cancer	DOID:0050686	0.189
disease of cellular proliferation	DOID:14566	0.189

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