Drosophila melanogaster

46 known processes

SPoCk (Dmel_CG32451)

Secretory Pathway Calcium atpase

(Aliases: anon-WO0118547.249,CG32451,CG14449,SPoCK,CG7651,Dmel\CG32451)

SPoCk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sensory perception of salty tasteGO:005091430.090
neurological system processGO:00508773580.073
single organism behaviorGO:00447083910.063
positive regulation of macromolecule metabolic processGO:00106044050.055
organonitrogen compound metabolic processGO:19015643180.054
Rat
actin filament based processGO:00300292200.052
sensory perceptionGO:00076001960.051
carbohydrate derivative metabolic processGO:19011352170.048
Rat
eye developmentGO:00016543230.046
store operated calcium entryGO:000211530.044
single organism catabolic processGO:00447122280.042
Rat
catabolic processGO:00090564090.041
Rat
digestive tract morphogenesisGO:00485461270.041
intracellular signal transductionGO:00355563000.039
negative regulation of gene expressionGO:00106293870.039
tube developmentGO:00352952440.038
camera type eye developmentGO:004301040.038
guanosine containing compound catabolic processGO:1901069740.036
cellular protein modification processGO:00064644380.036
regulation of cellular component biogenesisGO:00440872010.036
nucleobase containing small molecule metabolic processGO:00550861740.036
Rat
small molecule metabolic processGO:00442813050.034
Rat
organophosphate metabolic processGO:00196371950.034
Rat
single organism biosynthetic processGO:00447112060.033
gene silencingGO:00164581380.032
regulation of response to external stimulusGO:00321011150.031
embryonic hindgut morphogenesisGO:0048619480.031
nucleotide metabolic processGO:00091171610.031
Rat
negative regulation of nitrogen compound metabolic processGO:00511722650.030
response to organic substanceGO:00100332840.030
small gtpase mediated signal transductionGO:0007264880.030
positive regulation of response to stimulusGO:00485843230.030
regulation of gene silencingGO:0060968630.030
cellular response to chemical stimulusGO:00708871990.029
amine metabolic processGO:0009308120.029
negative regulation of cell communicationGO:00106482230.029
divalent inorganic cation transportGO:0072511300.029
nucleoside catabolic processGO:00091641120.028
Rat
regulation of cellular amine metabolic processGO:003323830.028
negative regulation of macromolecule biosynthetic processGO:00105582700.028
negative regulation of biosynthetic processGO:00098902770.027
hindgut morphogenesisGO:0007442580.027
cellular catabolic processGO:00442483720.026
Rat
negative regulation of rna metabolic processGO:00512532510.026
exocrine system developmentGO:00352721620.025
morphogenesis of an epitheliumGO:00020092760.025
organonitrogen compound catabolic processGO:19015651280.025
Rat
cellular amino acid metabolic processGO:0006520610.025
purine containing compound metabolic processGO:00725211550.025
Rat
g protein coupled receptor signaling pathwayGO:00071861360.025
cell motilityGO:00488702510.025
positive regulation of nucleobase containing compound metabolic processGO:00459353320.025
cation transportGO:00068121100.025
positive regulation of cell communicationGO:00106472500.025
salivary gland developmentGO:00074311620.024
embryo development ending in birth or egg hatchingGO:00097921520.024
cellular nitrogen compound catabolic processGO:00442701650.024
Rat
deathGO:00162652840.024
ribose phosphate metabolic processGO:00196931450.023
Rat
behavioral response to ethanolGO:0048149490.023
circadian behaviorGO:0048512760.023
salivary gland morphogenesisGO:00074351450.023
embryonic morphogenesisGO:00485982060.023
centrosome organizationGO:00512971630.023
posttranscriptional regulation of gene expressionGO:00106081450.023
heterocycle catabolic processGO:00467001660.023
Rat
organic cyclic compound catabolic processGO:19013611680.023
Rat
appendage morphogenesisGO:00351073970.023
developmental growthGO:00485892800.023
actin cytoskeleton organizationGO:00300362060.022
gland morphogenesisGO:00226121450.022
sensory organ morphogenesisGO:00905962600.022
malpighian tubule morphogenesisGO:0007443440.022
ribonucleoside metabolic processGO:00091191270.022
Rat
renal tubule developmentGO:0061326640.022
renal tubule morphogenesisGO:0061333440.022
body morphogenesisGO:001017120.021
growthGO:00400073590.021
organic substance catabolic processGO:19015753080.021
Rat
tube morphogenesisGO:00352391910.021
response to oxygen containing compoundGO:19017002000.021
positive regulation of signalingGO:00230562430.021
malpighian tubule developmentGO:0072002640.021
regulation of cellular protein metabolic processGO:00322682430.021
response to abiotic stimulusGO:00096283410.021
carbohydrate derivative catabolic processGO:19011361180.020
Rat
epithelial tube morphogenesisGO:0060562880.020
regulation of response to stressGO:00801342000.020
homeostatic processGO:00425921990.020
protein complex biogenesisGO:00702712010.020
protein complex assemblyGO:00064612000.020
response to biotic stimulusGO:00096072940.020
positive regulation of multicellular organismal processGO:00512401430.020
imaginal disc derived appendage morphogenesisGO:00351143950.019
regulation of phosphorus metabolic processGO:00511742100.019
regulation of mitotic cell cycleGO:00073461900.019
organic acid metabolic processGO:00060821030.019
eye morphogenesisGO:00485922600.019
ras protein signal transductionGO:0007265880.019
regulation of nucleotide metabolic processGO:0006140620.019
negative regulation of signalingGO:00230572190.019
regulation of molecular functionGO:00650092170.019
transcription from rna polymerase ii promoterGO:00063663680.019
cellular amine metabolic processGO:0044106120.019
positive regulation of protein metabolic processGO:00512471280.019
regulation of growthGO:00400082330.019
negative regulation of cellular biosynthetic processGO:00313272770.019
purine nucleotide metabolic processGO:00061631460.019
Rat
purine ribonucleotide catabolic processGO:00091541090.018
Rat
tissue deathGO:00162711020.018
digestive tract developmentGO:00485651490.018
positive regulation of nitrogen compound metabolic processGO:00511733540.018
rhythmic behaviorGO:0007622760.018
nucleobase containing compound catabolic processGO:00346551650.018
Rat
cellular ketone metabolic processGO:0042180240.018
nucleoside phosphate metabolic processGO:00067531620.018
Rat
positive regulation of biosynthetic processGO:00098913160.018
mitotic spindle organizationGO:00070522200.018
macromolecular complex assemblyGO:00650032560.018
appendage developmentGO:00487364010.017
regulation of multicellular organismal developmentGO:20000264140.017
regulation of catabolic processGO:00098941700.017
ribonucleotide metabolic processGO:00092591450.017
Rat
regulation of organelle organizationGO:00330431960.017
digestive system developmentGO:00551231490.017
cellular macromolecular complex assemblyGO:00346221530.017
localization of cellGO:00516742570.017
phosphorylationGO:00163102940.017
positive regulation of signal transductionGO:00099672230.017
positive regulation of cellular biosynthetic processGO:00313283160.016
regulation of cellular localizationGO:00603411360.016
nuclear divisionGO:00002803320.016
regulation of phosphate metabolic processGO:00192202100.016
olfactory behaviorGO:0042048970.016
cation transmembrane transportGO:0098655880.016
Rat
compound eye developmentGO:00487493070.016
regulation of intracellular transportGO:0032386640.016
regulation of cell differentiationGO:00455953020.016
regulation of immune system processGO:00026821760.016
oxoacid metabolic processGO:00434361030.016
response to radiationGO:00093141550.016
signal transduction by phosphorylationGO:00230141070.016
cellular homeostasisGO:0019725800.015
regulation of developmental growthGO:00486381740.015
negative regulation of rna biosynthetic processGO:19026792400.015
regulation of synapse organizationGO:00508071100.015
muscle structure developmentGO:00610612240.015
mapk cascadeGO:00001651070.015
regulation of cellular catabolic processGO:00313291570.015
purine ribonucleoside catabolic processGO:00461301120.015
Rat
regulation of localizationGO:00328792750.015
negative regulation of intracellular signal transductionGO:1902532570.015
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.015
regulation of gene expression epigeneticGO:00400291280.015
spindle organizationGO:00070512530.015
negative regulation of response to stimulusGO:00485852580.015
ribonucleotide catabolic processGO:00092611090.015
Rat
positive regulation of purine nucleotide metabolic processGO:1900544550.015
compound eye morphogenesisGO:00017452490.015
regulation of cellular amino acid metabolic processGO:000652100.015
negative regulation of protein metabolic processGO:0051248850.015
post embryonic appendage morphogenesisGO:00351203850.014
positive regulation of cell motilityGO:200014730.014
developmental programmed cell deathGO:00106231380.014
retina development in camera type eyeGO:006004140.014
programmed cell deathGO:00125012570.014
adult behaviorGO:00305341370.014
protein modification processGO:00362114380.014
wing disc morphogenesisGO:00074723440.014
regulation of cellular ketone metabolic processGO:001056530.014
protein phosphorylationGO:00064681690.014
sensory perception of chemical stimulusGO:00076061160.014
ribonucleoside catabolic processGO:00424541120.014
Rat
purine containing compound catabolic processGO:00725231120.014
Rat
carboxylic acid metabolic processGO:0019752920.014
gene silencing by rnaGO:0031047570.014
response to external biotic stimulusGO:00432072930.014
positive regulation of transcription dna templatedGO:00458932660.014
stem cell differentiationGO:00488631170.014
purine nucleoside metabolic processGO:00422781270.014
Rat
proteolysisGO:00065081920.014
tissue morphogenesisGO:00487292970.014
salt aversionGO:003519930.014
nucleoside triphosphate metabolic processGO:00091411200.014
Rat
renal system developmentGO:0072001720.014
negative regulation of cell deathGO:0060548810.014
central nervous system developmentGO:00074172010.014
histolysisGO:00075591020.013
negative regulation of transcription dna templatedGO:00458922370.013
cellular response to dna damage stimulusGO:00069742230.013
positive regulation of macromolecule biosynthetic processGO:00105572830.013
gtp catabolic processGO:0006184720.013
regulation of nucleoside metabolic processGO:0009118500.013
divalent metal ion transportGO:0070838260.013
autophagic cell deathGO:0048102830.013
male courtship behavior veined wing vibrationGO:0016545210.013
response to alcoholGO:0097305950.013
glycosyl compound catabolic processGO:19016581120.013
Rat
salivary gland cell autophagic cell deathGO:0035071830.013
detection of stimulus involved in sensory perceptionGO:0050906920.013
forebrain developmentGO:003090020.013
ribonucleoside triphosphate catabolic processGO:00092031080.013
Rat
negative regulation of cellular protein metabolic processGO:0032269850.013
defense response to other organismGO:00985422250.013
cellular ion homeostasisGO:0006873390.013
gland developmentGO:00487321910.012
negative regulation of mitotic cell cycleGO:00459301090.012
actin filament based movementGO:0030048260.012
positive regulation of rna biosynthetic processGO:19026802660.012
glycosyl compound metabolic processGO:19016571270.012
Rat
microtubule polymerization or depolymerizationGO:0031109390.012
epithelial cell differentiationGO:00308553220.012
response to hypoxiaGO:0001666530.012
positive regulation of catabolic processGO:00098961050.012
purine ribonucleotide metabolic processGO:00091501450.012
Rat
synaptic growth at neuromuscular junctionGO:00511241190.012
nucleoside metabolic processGO:00091161270.012
Rat
dna metabolic processGO:00062592270.012
purine nucleoside triphosphate metabolic processGO:00091441190.012
Rat
negative regulation of cellular component organizationGO:00511291080.012
endomembrane system organizationGO:00102561190.012
purine ribonucleoside metabolic processGO:00461281270.012
Rat
gtp metabolic processGO:0046039720.012
guanosine containing compound metabolic processGO:1901068740.012
chromosome organizationGO:00512763600.012
circulatory system processGO:0003013370.012
hindgut developmentGO:0061525580.012
response to extracellular stimulusGO:00099911160.012
regulation of gtpase activityGO:0043087440.011
urogenital system developmentGO:0001655720.011
regulation of phosphorylationGO:00423251470.011
organic hydroxy compound metabolic processGO:1901615830.011
positive regulation of cellular catabolic processGO:0031331950.011
protein localizationGO:00081042840.011
ion transportGO:00068111450.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
Rat
regulation of intracellular signal transductionGO:19025312360.011
ribonucleoside triphosphate metabolic processGO:00091991190.011
Rat
regulation of gtp catabolic processGO:0033124440.011
long term memoryGO:0007616620.011
defense responseGO:00069523000.011
regulation of ras protein signal transductionGO:0046578930.011
negative regulation of signal transductionGO:00099682060.011
negative regulation of nucleic acid templated transcriptionGO:19035072400.011
apoptotic processGO:00069151590.011
histone modificationGO:00165701060.011
telencephalon developmentGO:002153720.011
regulation of hydrolase activityGO:0051336970.011
vesicle organizationGO:0016050440.010
positive regulation of gene expressionGO:00106282900.010
response to oxygen levelsGO:0070482590.010
endocytosisGO:00068973100.010
membrane organizationGO:00610241120.010
mesenchymal cell developmentGO:001403110.010
eye antennal disc morphogenesisGO:0007455340.010
organic substance transportGO:00717022570.010
positive regulation of molecular functionGO:00440931360.010
covalent chromatin modificationGO:00165691060.010
negative regulation of nucleobase containing compound metabolic processGO:00459342610.010
cognitionGO:00508901410.010
organophosphate catabolic processGO:00464341120.010
Rat
response to decreased oxygen levelsGO:0036293580.010
synaptic target recognitionGO:0008039450.010
cell divisionGO:00513012480.010
hindbrain developmentGO:003090220.010
establishment of localization in cellGO:00516494020.010
imaginal disc derived appendage developmentGO:00487373990.010
macromolecule catabolic processGO:00090571610.010

SPoCk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.072
cardiovascular system diseaseDOID:128700.030
nervous system diseaseDOID:86300.024
sensory system diseaseDOID:005015500.019
eye and adnexa diseaseDOID:149200.019
eye diseaseDOID:561400.019
musculoskeletal system diseaseDOID:1700.013
central nervous system diseaseDOID:33100.010