Drosophila melanogaster

66 known processes

up (Dmel_CG7107)

upheld

(Aliases: BcDNA:LD08591,DmTpnT,upheld2,FBgn0004169,wupB,Tn-T,int,dro TnT,TpnT,tnT,CG7107,Dmel\CG7107,TnT)

up biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
sarcomere organizationGO:0045214260.988
myofibril assemblyGO:0030239360.973
cellular component assembly involved in morphogenesisGO:00109271510.899
striated muscle cell differentiationGO:0051146900.809
skeletal muscle adaptationGO:004350110.806
Mouse
regulation of actin filament depolymerizationGO:003083430.784
muscle structure developmentGO:00610612240.781
muscle cell developmentGO:0055001500.772
muscle cell differentiationGO:00426921030.740
actomyosin structure organizationGO:0031032560.716
negative regulation of actin filament depolymerizationGO:003083520.557
protein complex biogenesisGO:00702712010.510
Worm
actin filament based processGO:00300292200.486
organelle assemblyGO:00709251980.477
adult somatic muscle developmentGO:0007527140.416
muscle thin filament assemblyGO:007168950.384
striated muscle cell developmentGO:0055002500.381
tube developmentGO:00352952440.361
Zebrafish
actin filament organizationGO:00070151260.333
brain developmentGO:00074201200.333
molting cycleGO:0042303560.244
mesoderm developmentGO:0007498780.242
skeletal muscle organ developmentGO:0060538480.223
organic substance catabolic processGO:19015753080.222
Human Worm
positive regulation of nucleobase containing compound metabolic processGO:00459353320.218
Human
striated muscle tissue developmentGO:0014706270.216
Human Zebrafish Mouse
purine ribonucleoside monophosphate metabolic processGO:0009167500.212
Human
protein complex assemblyGO:00064612000.204
Worm
metal ion homeostasisGO:0055065440.183
somatic muscle developmentGO:0007525660.172
Worm
striated muscle myosin thick filament assemblyGO:007168830.172
Worm
vesicle mediated transportGO:00161923810.172
Worm
regulation of cellular catabolic processGO:00313291570.171
Human
cellular protein complex assemblyGO:0043623710.169
Worm
localization of cellGO:00516742570.162
Zebrafish
positive regulation of nitrogen compound metabolic processGO:00511733540.157
Human
nucleoside triphosphate catabolic processGO:00091431080.151
Human
actin cytoskeleton organizationGO:00300362060.148
purine nucleoside metabolic processGO:00422781270.147
Human
adult behaviorGO:00305341370.144
muscle organ developmentGO:00075171270.142
catabolic processGO:00090564090.137
Human Worm
skeletal muscle myosin thick filament assemblyGO:003024130.120
body morphogenesisGO:001017120.114
cellular macromolecular complex assemblyGO:00346221530.112
Worm
purine nucleotide catabolic processGO:00061951090.112
Human
ion homeostasisGO:0050801550.111
nucleoside triphosphate metabolic processGO:00091411200.106
Human
skeletal muscle tissue developmentGO:0007519130.105
nucleoside phosphate metabolic processGO:00067531620.102
Human
ribose phosphate metabolic processGO:00196931450.101
Human
purine ribonucleotide metabolic processGO:00091501450.100
Human
cation homeostasisGO:0055080510.099
endocytosisGO:00068973100.097
Worm
response to oxygen containing compoundGO:19017002000.095
circulatory system developmentGO:0072359820.092
Human Zebrafish Mouse
tissue morphogenesisGO:00487292970.089
Human Zebrafish Mouse
glycosyl compound metabolic processGO:19016571270.083
Human
cellular catabolic processGO:00442483720.082
Human
carbohydrate derivative metabolic processGO:19011352170.080
Human
cellular nitrogen compound catabolic processGO:00442701650.079
Human
organonitrogen compound catabolic processGO:19015651280.078
Human
purine ribonucleoside triphosphate metabolic processGO:00092051190.078
Human
muscle tissue morphogenesisGO:006041520.077
Human Zebrafish Mouse
purine containing compound metabolic processGO:00725211550.077
Human
macromolecular complex assemblyGO:00650032560.074
Worm
actin filament cappingGO:005169320.073
actin filament based movementGO:0030048260.073
Human
muscle organ morphogenesisGO:004864470.070
actin filament depolymerizationGO:003004250.068
heart processGO:0003015370.068
Human Zebrafish Mouse
ribonucleotide catabolic processGO:00092611090.067
Human
cellular response to reactive oxygen speciesGO:0034614140.067
negative regulation of protein depolymerizationGO:1901880230.066
ribonucleoside monophosphate metabolic processGO:0009161510.065
Human
anatomical structure homeostasisGO:0060249970.064
regulation of localizationGO:00328792750.060
nucleotide metabolic processGO:00091171610.060
Human
positive regulation of catalytic activityGO:00430851180.059
Human
regulation of protein depolymerizationGO:1901879270.058
purine ribonucleoside triphosphate catabolic processGO:00092071080.058
Human
protein depolymerizationGO:0051261310.053
myotube differentiationGO:0014902460.053
regulation of hydrolase activityGO:0051336970.052
Human
cellular homeostasisGO:0019725800.052
protein modification processGO:00362114380.052
cellular metal ion homeostasisGO:0006875310.051
cardiac muscle tissue developmentGO:004873890.051
Human Zebrafish Mouse
posttranscriptional regulation of gene expressionGO:00106081450.051
regulation of molecular functionGO:00650092170.050
Human
heart contractionGO:0060047260.050
Human Zebrafish Mouse
cardiocyte differentiationGO:0035051290.050
regulation of actin filament lengthGO:0030832270.049
positive regulation of cellular component organizationGO:00511301560.049
regulation of cellular localizationGO:00603411360.049
phagocytosisGO:00069092150.049
negative regulation of protein polymerizationGO:003227270.049
phosphorylationGO:00163102940.048
regulation of cell deathGO:00109411730.047
organonitrogen compound metabolic processGO:19015643180.045
Human
nucleoside monophosphate metabolic processGO:0009123520.045
Human
muscle contractionGO:0006936130.044
Human Zebrafish Mouse Worm
purine nucleoside triphosphate metabolic processGO:00091441190.044
Human
digestive tract developmentGO:00485651490.043
small molecule metabolic processGO:00442813050.041
Human
cardiovascular system developmentGO:0072358820.041
Human Zebrafish Mouse
organophosphate metabolic processGO:00196371950.041
Human
positive regulation of phosphorus metabolic processGO:00105621390.041
Human
positive regulation of transportGO:0051050920.040
carbohydrate derivative catabolic processGO:19011361180.040
Human
chemical homeostasisGO:0048878920.040
purine ribonucleoside metabolic processGO:00461281270.040
Human
regulation of vesicle mediated transportGO:0060627590.039
actin filament bundle organizationGO:0061572280.039
ribonucleoside triphosphate catabolic processGO:00092031080.039
Human
regulation of cellular component biogenesisGO:00440872010.039
organophosphate catabolic processGO:00464341120.039
Human
response to abiotic stimulusGO:00096283410.039
reproductive behaviorGO:00190981220.039
regulation of cellular component movementGO:0051270420.037
actin polymerization or depolymerizationGO:0008154310.037
cellular divalent inorganic cation homeostasisGO:0072503230.037
regulation of apoptotic processGO:00429811300.036
homeostatic processGO:00425921990.036
imaginal disc derived appendage developmentGO:00487373990.036
regulation of cytoskeleton organizationGO:0051493890.035
striated muscle adaptationGO:001488810.034
Mouse
negative regulation of cytoskeleton organizationGO:0051494300.034
regulation of actin cytoskeleton organizationGO:0032956420.033
positive regulation of cellular catabolic processGO:0031331950.033
Human
ribonucleoside catabolic processGO:00424541120.033
Human
positive regulation of catabolic processGO:00098961050.032
Human
regulation of cell differentiationGO:00455953020.032
regulation of purine nucleotide metabolic processGO:1900542620.032
Human
positive regulation of organelle organizationGO:0010638650.032
positive regulation of protein import into nucleusGO:0042307210.032
ribonucleoside metabolic processGO:00091191270.031
Human
ribonucleotide metabolic processGO:00092591450.031
Human
purine nucleoside catabolic processGO:00061521120.030
Human
biological adhesionGO:00226101380.029
regulation of catabolic processGO:00098941700.029
Human
response to organic substanceGO:00100332840.029
calcium ion homeostasisGO:0055074230.028
nucleobase containing compound catabolic processGO:00346551650.028
Human
mapk cascadeGO:00001651070.028
regulation of cell migrationGO:0030334220.028
single organism catabolic processGO:00447122280.028
Human
skeletal muscle fiber developmentGO:004874130.028
purine nucleotide metabolic processGO:00061631460.028
Human
ribonucleoside triphosphate metabolic processGO:00091991190.028
Human
multicellular organismal reproductive behaviorGO:00330571100.027
positive regulation of biosynthetic processGO:00098913160.027
growthGO:00400073590.027
muscle tissue developmentGO:0060537300.027
Human Zebrafish Mouse
organelle fissionGO:00482853400.027
ovipositionGO:0018991190.027
primary amino compound metabolic processGO:190116020.026
adult locomotory behaviorGO:0008344760.026
larval developmentGO:00021641040.025
Worm
nucleobase containing small molecule metabolic processGO:00550861740.025
Human
cellular response to chemical stimulusGO:00708871990.025
striated muscle contractionGO:000694150.025
Zebrafish
regulation of catalytic activityGO:00507901850.025
Human
regulation of organelle organizationGO:00330431960.025
nucleoside catabolic processGO:00091641120.025
Human
ovulationGO:003072840.024
Worm
regulation of multicellular organismal developmentGO:20000264140.023
aromatic compound catabolic processGO:00194391660.023
Human
muscle adaptationGO:004350010.023
Mouse
central nervous system developmentGO:00074172010.023
morphogenesis of an epitheliumGO:00020092760.023
Zebrafish
cell adhesionGO:00071551360.023
response to endogenous stimulusGO:00097191190.023
positive regulation of atp catabolic processGO:190329130.023
Human
cellular chemical homeostasisGO:0055082400.022
alditol phosphate metabolic processGO:005264620.022
purine ribonucleoside catabolic processGO:00461301120.021
Human
regulation of locomotionGO:0040012420.021
organic cyclic compound catabolic processGO:19013611680.021
Human
catecholamine biosynthetic processGO:004242330.020
secretionGO:00469031090.020
response to reactive oxygen speciesGO:0000302240.020
positive regulation of nucleoside metabolic processGO:0045979470.020
Human
multi multicellular organism processGO:00447061230.020
heterocycle catabolic processGO:00467001660.020
Human
regulation of protein complex disassemblyGO:0043244290.020
macromolecule catabolic processGO:00090571610.019
Worm
regulation of protein polymerizationGO:0032271280.019
regulation of phosphorus metabolic processGO:00511742100.019
Human
nucleoside monophosphate catabolic processGO:0009125390.019
Human
regulation of immune system processGO:00026821760.018
single organism carbohydrate metabolic processGO:0044723720.018
stem cell differentiationGO:00488631170.018
Zebrafish
actin filament bundle assemblyGO:0051017260.018
regulation of sarcomere organizationGO:006029720.018
purine nucleoside monophosphate metabolic processGO:0009126500.018
Human
cellular protein modification processGO:00064644380.018
response to hypoxiaGO:0001666530.018
positive regulation of signal transductionGO:00099672230.018
negative regulation of actin filament polymerizationGO:003083770.017
regulation of transportGO:00510491810.017
carbohydrate metabolic processGO:0005975820.017
regulation of actin polymerization or depolymerizationGO:0008064270.017
cell divisionGO:00513012480.016
purine ribonucleotide catabolic processGO:00091541090.016
Human
positive regulation of macromolecule biosynthetic processGO:00105572830.016
skeletal myofibril assemblyGO:001486660.015
camera type eye developmentGO:004301040.015
regulation of phosphate metabolic processGO:00192202100.015
Human
response to organic cyclic compoundGO:0014070890.015
purine ribonucleoside monophosphate catabolic processGO:0009169380.015
Human
cellular response to oxygen containing compoundGO:1901701790.015
purine nucleoside monophosphate catabolic processGO:0009128380.015
Human
protein secretionGO:0009306450.015
autophagyGO:00069141080.015
nucleoside phosphate catabolic processGO:19012921100.015
Human
positive regulation of nucleotide catabolic processGO:0030813460.015
Human
cellular response to organic substanceGO:00713101320.014
gonad developmentGO:0008406500.014
mitotic nuclear divisionGO:00070672130.014
wing disc morphogenesisGO:00074723440.014
atp catabolic processGO:0006200380.014
Human
immune system processGO:00023763470.014
Zebrafish
response to oxygen levelsGO:0070482590.014
negative regulation of response to stimulusGO:00485852580.014
protein localizationGO:00081042840.014
negative regulation of organelle organizationGO:0010639560.013
heart developmentGO:0007507820.013
Human Zebrafish Mouse
myotube cell developmentGO:001490430.013
protein phosphorylationGO:00064681690.013
atp metabolic processGO:0046034490.013
Human
head developmentGO:00603221350.013
establishment of localization in cellGO:00516494020.013
stress activated mapk cascadeGO:0051403520.013
cell motilityGO:00488702510.013
Zebrafish
protein transportGO:00150311550.012
negative regulation of protein complex disassemblyGO:0043242230.012
positive regulation of purine nucleotide metabolic processGO:1900544550.012
Human
neurological system processGO:00508773580.012
positive regulation of molecular functionGO:00440931360.012
Human
cardiac muscle cell differentiationGO:005500740.012
oxoacid metabolic processGO:00434361030.012
muscle system processGO:0003012210.012
Human Zebrafish Mouse Worm
reproductive system developmentGO:0061458740.012
regulation of intracellular protein transportGO:0033157460.012
regulation of response to stressGO:00801342000.012
cellular cation homeostasisGO:0030003380.012
response to lipopolysaccharideGO:003249640.012
regulation of establishment of protein localizationGO:0070201610.012
regulation of transcription from rna polymerase ii promoterGO:00063573780.011
positive regulation of cell deathGO:0010942690.011
circulatory system processGO:0003013370.011
Human Zebrafish Mouse
pharynx developmentGO:006046510.011
positive regulation of cellular biosynthetic processGO:00313283160.011
sex differentiationGO:0007548810.011
cellular macromolecule localizationGO:00707272200.011
regulation of secretionGO:0051046440.011
digestive system developmentGO:00551231490.011
cellular response to oxidative stressGO:0034599280.011
regulation of phosphatase activityGO:001092130.011
regulation of anatomical structure sizeGO:00900661630.011
regulation of growthGO:00400082330.011
purine containing compound catabolic processGO:00725231120.011
Human
embryo development ending in birth or egg hatchingGO:00097921520.011
establishment of protein localizationGO:00451841630.011
positive regulation of actin filament bundle assemblyGO:003223330.010
myosin filament assemblyGO:003103450.010
Worm
negative regulation of gene expressionGO:00106293870.010
regulation of protein complex assemblyGO:0043254420.010
positive regulation of signalingGO:00230562430.010
ribonucleoside monophosphate catabolic processGO:0009158390.010
Human
kidney developmentGO:000182230.010
Zebrafish

up disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
myopathyDOID:42300.304
Human
muscular diseaseDOID:008000000.304
Human
heart diseaseDOID:11400.304
Human
cardiomyopathyDOID:005070000.304
Human
disease of anatomical entityDOID:700.304
Human
muscle tissue diseaseDOID:6600.304
Human
musculoskeletal system diseaseDOID:1700.304
Human
cardiovascular system diseaseDOID:128700.304
Human
dilated cardiomyopathyDOID:1293000.147
Human
intrinsic cardiomyopathyDOID:006003600.147
Human
nervous system diseaseDOID:86300.012