Drosophila melanogaster

48 known processes

Adam (Dmel_CG12131)

CG12131 gene product from transcript CG12131-RA

(Aliases: 5.3,E,l(2)46Cf,l(2)46CFd,CG12131,eIF3-S1,Dmel\CG12131,l(2)k13906)

Adam biological process predictions


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Biological processGO term IDProcess sizeProbabilityFunc Analog Org
positive regulation of macromolecule metabolic processGO:00106044050.525
positive regulation of cellular biosynthetic processGO:00313283160.410
positive regulation of transcription dna templatedGO:00458932660.383
establishment of localization in cellGO:00516494020.354
positive regulation of rna biosynthetic processGO:19026802660.268
positive regulation of gene expressionGO:00106282900.255
organic substance transportGO:00717022570.255
protein modification processGO:00362114380.237
positive regulation of rna metabolic processGO:00512542710.232
positive regulation of nucleic acid templated transcriptionGO:19035082660.219
dna integrity checkpointGO:0031570810.204
positive regulation of macromolecule biosynthetic processGO:00105572830.196
positive regulation of biosynthetic processGO:00098913160.192
negative regulation of rna biosynthetic processGO:19026792400.171
positive regulation of nucleobase containing compound metabolic processGO:00459353320.166
regulation of transportGO:00510491810.156
macromolecular complex assemblyGO:00650032560.145
positive regulation of multicellular organismal processGO:00512401430.134
negative regulation of transcription dna templatedGO:00458922370.132
negative regulation of nucleic acid templated transcriptionGO:19035072400.117
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.111
positive regulation of transportGO:0051050920.110
protein transmembrane transportGO:007180640.110
negative regulation of gene expressionGO:00106293870.109
dendrite developmentGO:00163582040.109
positive regulation of cell communicationGO:00106472500.108
rna localizationGO:00064031150.107
vesicle mediated transportGO:00161923810.101
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.099
g2 dna damage checkpointGO:0031572690.099
negative regulation of nucleobase containing compound metabolic processGO:00459342610.098
regulation of transcription from rna polymerase ii promoterGO:00063573780.097
single organism cellular localizationGO:19025801800.096
phosphorylationGO:00163102940.096
intracellular protein transportGO:00068861040.090
regulation of mitotic cell cycleGO:00073461900.089
growthGO:00400073590.088
regulation of multicellular organismal developmentGO:20000264140.085
cellular macromolecule localizationGO:00707272200.081
cellular protein modification processGO:00064644380.079
intracellular protein transmembrane importGO:004474340.078
regulation of cell differentiationGO:00455953020.077
cell cycle checkpointGO:0000075950.076
establishment of protein localizationGO:00451841630.074
regulation of neuron differentiationGO:00456641030.068
cellular nitrogen compound catabolic processGO:00442701650.066
positive regulation of developmental processGO:00510941430.066
regulation of neurogenesisGO:00507671580.065
negative regulation of macromolecule biosynthetic processGO:00105582700.065
mitotic g2 dna damage checkpointGO:0007095690.065
response to organic substanceGO:00100332840.060
lipid localizationGO:0010876540.060
cellular response to dna damage stimulusGO:00069742230.059
cellular macromolecular complex assemblyGO:00346221530.058
actin cytoskeleton organizationGO:00300362060.057
cell deathGO:00082192790.056
oocyte constructionGO:00073081120.056
actin filament based processGO:00300292200.056
endocytosisGO:00068973100.054
nucleobase containing compound catabolic processGO:00346551650.052
aromatic compound catabolic processGO:00194391660.050
negative regulation of biosynthetic processGO:00098902770.048
cell cell signaling involved in cell fate commitmentGO:00451682100.047
intracellular protein transmembrane transportGO:006500240.047
spindle organizationGO:00070512530.046
cellular protein complex assemblyGO:0043623710.045
regulation of heart morphogenesisGO:200082630.044
maternal determination of anterior posterior axis embryoGO:0008358740.044
embryo development ending in birth or egg hatchingGO:00097921520.044
positive regulation of nitrogen compound metabolic processGO:00511733540.044
mitotic g2 m transition checkpointGO:0044818700.044
regulation of establishment of protein localizationGO:0070201610.043
negative regulation of cellular metabolic processGO:00313243820.043
cytoplasmic transportGO:00164821300.041
protein prenylationGO:001834230.041
negative regulation of cellular biosynthetic processGO:00313272770.040
dna damage checkpointGO:0000077780.039
regulation of developmental growthGO:00486381740.039
regulation of cell developmentGO:00602842150.038
negative regulation of mitotic cell cycleGO:00459301090.038
deathGO:00162652840.038
protein importGO:0017038550.038
negative regulation of nitrogen compound metabolic processGO:00511722650.036
cell adhesionGO:00071551360.035
nucleocytoplasmic transportGO:0006913720.035
cell divisionGO:00513012480.035
protein localizationGO:00081042840.035
oocyte axis specificationGO:00073091080.034
protein complex biogenesisGO:00702712010.034
negative regulation of cell cycle phase transitionGO:19019881030.034
maintenance of locationGO:0051235730.034
taxisGO:00423303040.033
regulation of localizationGO:00328792750.033
regulation of protein metabolic processGO:00512462560.033
secretionGO:00469031090.032
programmed cell deathGO:00125012570.031
regulation of cell cycle processGO:00105641810.031
cellular protein localizationGO:00346131600.030
regulation of growthGO:00400082330.030
regulation of cellular protein metabolic processGO:00322682430.030
membrane organizationGO:00610241120.030
protein targetingGO:0006605640.030
single organism intracellular transportGO:19025822070.028
cellular response to chemical stimulusGO:00708871990.028
secretion by cellGO:00329401010.028
regulation of cellular localizationGO:00603411360.028
cytoplasm organizationGO:0007028640.028
transmembrane transportGO:00550851390.028
striated muscle myosin thick filament assemblyGO:007168830.027
positive regulation of neurogenesisGO:0050769410.027
body morphogenesisGO:001017120.027
lateral inhibitionGO:00463312060.026
defense response to bacteriumGO:00427421780.025
developmental maturationGO:00217001720.025
regulation of phosphatase activityGO:001092130.025
protein processingGO:0016485680.025
cellular macromolecule catabolic processGO:00442651360.025
positive regulation of signal transductionGO:00099672230.025
intracellular transportGO:00469072280.025
dendrite morphogenesisGO:00488131990.025
lipid storageGO:0019915380.024
response to abiotic stimulusGO:00096283410.024
regulation of nervous system developmentGO:00519602480.024
cellular protein complex disassemblyGO:0043624350.024
developmental growthGO:00485892800.024
nuclear transportGO:0051169720.023
intracellular signal transductionGO:00355563000.023
dna metabolic processGO:00062592270.022
heterocycle catabolic processGO:00467001660.022
organic cyclic compound catabolic processGO:19013611680.022
organelle fissionGO:00482853400.021
regulation of cellular component biogenesisGO:00440872010.021
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.021
regulation of protein transportGO:0051223570.021
apoptotic processGO:00069151590.020
regulation of cell shapeGO:00083601130.020
posttranscriptional regulation of gene expressionGO:00106081450.020
multicellular organism growthGO:0035264460.020
cell cycle phase transitionGO:00447701400.020
regulation of dendrite developmentGO:0050773370.020
striated muscle cell differentiationGO:0051146900.020
cell migrationGO:00164772380.019
single organism membrane organizationGO:0044802930.019
oocyte developmentGO:00485991240.019
translational terminationGO:000641520.019
mitotic spindle organizationGO:00070522200.019
mitotic cell cycle checkpointGO:0007093880.019
regulation of cell deathGO:00109411730.019
smoothened signaling pathwayGO:0007224490.019
regulation of protein localizationGO:0032880760.018
positive regulation of nervous system developmentGO:0051962690.018
catabolic processGO:00090564090.017
organic substance catabolic processGO:19015753080.017
positive regulation of response to stimulusGO:00485843230.017
response to biotic stimulusGO:00096072940.017
regionalizationGO:00030024160.017
localization of cellGO:00516742570.017
arp2 3 complex mediated actin nucleationGO:003431430.017
negative regulation of rna metabolic processGO:00512532510.016
negative regulation of cell cycle processGO:00109481090.016
response to bacteriumGO:00096171980.016
regulation of cell cycleGO:00517262910.016
axonogenesisGO:00074092900.016
response to other organismGO:00517072930.015
carbohydrate derivative metabolic processGO:19011352170.015
dorsal ventral pattern formationGO:00099531330.015
regulation of anatomical structure morphogenesisGO:00226032420.014
negative regulation of cell cycleGO:00457861160.014
positive regulation of cell developmentGO:0010720610.014
negative regulation of protein metabolic processGO:0051248850.013
oocyte differentiationGO:00099941450.013
spindle elongationGO:0051231830.013
cellular response to endogenous stimulusGO:0071495800.013
mitotic dna damage checkpointGO:0044773740.013
phagocytosisGO:00069092150.013
negative regulation of phosphatase activityGO:001092330.013
regulation of cell proliferationGO:00421271630.013
protein complex assemblyGO:00064612000.012
macromolecule catabolic processGO:00090571610.012
developmental programmed cell deathGO:00106231380.012
multicellular organismal agingGO:00102591400.012
regulation of protein complex assemblyGO:0043254420.012
negative regulation of mitotic cell cycle phase transitionGO:19019911030.012
segmentationGO:00352822070.012
ribonucleoprotein complex subunit organizationGO:0071826280.012
mitochondrion organizationGO:0007005650.012
negative regulation of cellular protein metabolic processGO:0032269850.012
intracellular mrna localization involved in pattern specification processGO:0060810560.012
regulation of apoptotic processGO:00429811300.011
endomembrane system organizationGO:00102561190.011
regulation of phosphorylationGO:00423251470.011
regulation of dna metabolic processGO:0051052340.011
positive regulation of developmental growthGO:0048639620.011
pole plasm assemblyGO:0007315610.011
receptor mediated endocytosisGO:0006898210.011
photoreceptor cell differentiationGO:00465301700.011
cell motilityGO:00488702510.011
ras protein signal transductionGO:0007265880.011
adult behaviorGO:00305341370.011
immune system processGO:00023763470.011
small gtpase mediated signal transductionGO:0007264880.011
regulation of neuron projection developmentGO:0010975690.011
intracellular mrna localization involved in anterior posterior axis specificationGO:0060811530.011
positive regulation of growthGO:0045927750.010
regulation of hydrolase activityGO:0051336970.010
protein secretionGO:0009306450.010
response to external biotic stimulusGO:00432072930.010
tissue deathGO:00162711020.010

Adam disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
muscle tissue diseaseDOID:6600.017
musculoskeletal system diseaseDOID:1700.017
disease of anatomical entityDOID:700.017
muscular diseaseDOID:008000000.017
myopathyDOID:42300.011