Drosophila melanogaster

2 known processes

hrg (Dmel_CG9854)

hiiragi

(Aliases: PAP,Pap,l(2)k07619,l(2)07619,Dmel\CG9854,CG9854)

hrg biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
negative regulation of nucleobase containing compound metabolic processGO:00459342610.923
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.780
regulation of intracellular signal transductionGO:19025312360.512
dendrite developmentGO:00163582040.449
negative regulation of rna metabolic processGO:00512532510.407
phosphorylationGO:00163102940.309
intracellular signal transductionGO:00355563000.283
negative regulation of macromolecule biosynthetic processGO:00105582700.265
transcription from rna polymerase ii promoterGO:00063663680.258
positive regulation of cell communicationGO:00106472500.251
positive regulation of macromolecule metabolic processGO:00106044050.240
protein modification processGO:00362114380.222
positive regulation of signal transductionGO:00099672230.215
regulation of cellular protein metabolic processGO:00322682430.212
locomotory behaviorGO:00076261760.208
regulation of cell deathGO:00109411730.197
mrna metabolic processGO:00160711240.196
negative regulation of transcription dna templatedGO:00458922370.189
positive regulation of rna biosynthetic processGO:19026802660.181
cellular protein modification processGO:00064644380.181
positive regulation of signalingGO:00230562430.171
positive regulation of response to stimulusGO:00485843230.155
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.155
negative regulation of gene expressionGO:00106293870.153
regulation of multicellular organismal developmentGO:20000264140.151
Worm
notch signaling pathwayGO:00072191200.151
deathGO:00162652840.149
Worm
positive regulation of protein metabolic processGO:00512471280.149
positive regulation of developmental processGO:00510941430.146
cell deathGO:00082192790.141
Worm
negative regulation of nitrogen compound metabolic processGO:00511722650.141
positive regulation of intracellular signal transductionGO:19025331160.133
regulation of notch signaling pathwayGO:00085931000.132
negative regulation of nucleic acid templated transcriptionGO:19035072400.129
negative regulation of cellular biosynthetic processGO:00313272770.122
central nervous system developmentGO:00074172010.119
regulation of multi organism processGO:00439001310.115
positive regulation of phosphorus metabolic processGO:00105621390.111
negative regulation of developmental processGO:00510932010.111
Worm
regulation of protein metabolic processGO:00512462560.109
negative regulation of response to stimulusGO:00485852580.108
positive regulation of nucleobase containing compound metabolic processGO:00459353320.108
protein phosphorylationGO:00064681690.106
head developmentGO:00603221350.105
anterior posterior axis specificationGO:00099481090.101
regulation of dendrite morphogenesisGO:0048814280.099
negative regulation of rna biosynthetic processGO:19026792400.099
positive regulation of phosphate metabolic processGO:00459371390.099
rna processingGO:00063961470.099
Human
cell migrationGO:00164772380.098
regulation of response to stressGO:00801342000.096
organelle fissionGO:00482853400.096
localization of cellGO:00516742570.094
nuclear divisionGO:00002803320.091
heterocycle catabolic processGO:00467001660.086
cell cell signaling involved in cell fate commitmentGO:00451682100.085
positive regulation of biosynthetic processGO:00098913160.084
anterior posterior pattern specificationGO:00099521360.083
regulation of phosphorus metabolic processGO:00511742100.082
developmental maturationGO:00217001720.081
protein modification by small protein removalGO:0070646280.081
positive regulation of transcription dna templatedGO:00458932660.078
dorsal ventral pattern formationGO:00099531330.078
regulation of phosphate metabolic processGO:00192202100.078
cellular response to endogenous stimulusGO:0071495800.077
cardiocyte differentiationGO:0035051290.075
positive regulation of cellular amino acid metabolic processGO:004576400.075
positive regulation of macromolecule biosynthetic processGO:00105572830.074
embryonic development via the syncytial blastodermGO:00017001480.073
programmed cell deathGO:00125012570.071
Worm
spermatid differentiationGO:00485151140.071
regulation of ras protein signal transductionGO:0046578930.070
immune system processGO:00023763470.070
segmentationGO:00352822070.069
negative regulation of cell cycleGO:00457861160.068
negative regulation of cell communicationGO:00106482230.068
guanosine containing compound catabolic processGO:1901069740.068
cellular catabolic processGO:00442483720.067
blastoderm segmentationGO:00073501590.065
cytoplasmic transportGO:00164821300.065
regulation of mitotic cell cycleGO:00073461900.065
regulation of gene expression epigeneticGO:00400291280.064
immune effector processGO:0002252980.064
gland developmentGO:00487321910.063
positive regulation of cellular biosynthetic processGO:00313283160.062
regulation of cell differentiationGO:00455953020.062
positive regulation of cellular amine metabolic processGO:003324000.060
regulation of nervous system developmentGO:00519602480.060
macromolecular complex assemblyGO:00650032560.060
positive regulation of nucleic acid templated transcriptionGO:19035082660.059
ras protein signal transductionGO:0007265880.058
positive regulation of cellular protein metabolic processGO:00322701180.057
cell motilityGO:00488702510.057
cellular macromolecule catabolic processGO:00442651360.056
larval developmentGO:00021641040.056
Worm
negative regulation of signalingGO:00230572190.056
defense response to other organismGO:00985422250.056
body morphogenesisGO:001017120.055
Worm
response to abiotic stimulusGO:00096283410.054
regulation of dendrite developmentGO:0050773370.053
cell divisionGO:00513012480.053
organic substance catabolic processGO:19015753080.052
cellular nitrogen compound catabolic processGO:00442701650.052
male gamete generationGO:00482322010.052
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.051
regulation of organ morphogenesisGO:2000027780.051
regulation of programmed cell deathGO:00430671520.051
regulation of cellular ketone metabolic processGO:001056530.051
small molecule metabolic processGO:00442813050.050
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.050
semaphorin plexin signaling pathwayGO:007152640.050
organonitrogen compound metabolic processGO:19015643180.049
catabolic processGO:00090564090.049
mapk cascadeGO:00001651070.048
salivary gland morphogenesisGO:00074351450.047
epithelial cell developmentGO:00020642740.047
negative regulation of multicellular organismal processGO:00512411420.047
Worm
cellular protein complex assemblyGO:0043623710.047
eye developmentGO:00016543230.047
positive regulation of rna metabolic processGO:00512542710.046
exocrine system developmentGO:00352721620.045
positive regulation of gene expressionGO:00106282900.044
regulation of organelle organizationGO:00330431960.044
urogenital system developmentGO:0001655720.044
gliogenesisGO:0042063800.044
regulation of embryonic developmentGO:0045995680.043
microtubule polymerization or depolymerizationGO:0031109390.043
regulation of glial cell differentiationGO:004568510.042
positive regulation of nitrogen compound metabolic processGO:00511733540.042
macromolecule catabolic processGO:00090571610.042
mitotic nuclear divisionGO:00070672130.042
enzyme linked receptor protein signaling pathwayGO:00071671790.042
nucleobase containing small molecule metabolic processGO:00550861740.041
spindle organizationGO:00070512530.040
spermatogenesisGO:00072832000.040
gtp catabolic processGO:0006184720.039
cellular response to growth factor stimulusGO:0071363300.039
imaginal disc derived leg segmentationGO:0036011260.039
regulation of cell cycleGO:00517262910.039
jak stat cascadeGO:0007259490.039
gtp metabolic processGO:0046039720.039
negative regulation of cell deathGO:0060548810.039
regulation of immune system processGO:00026821760.039
cranial nerve developmentGO:002154510.039
cellular response to organic substanceGO:00713101320.039
telencephalon developmentGO:002153720.038
regulation of gene silencingGO:0060968630.038
mrna processingGO:00063971040.038
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.037
cellular response to transforming growth factor beta stimulusGO:0071560180.037
mesenchymal cell differentiationGO:004876210.037
negative regulation of cellular metabolic processGO:00313243820.037
apoptotic processGO:00069151590.037
Worm
carbohydrate derivative catabolic processGO:19011361180.037
digestive system developmentGO:00551231490.037
cellular protein localizationGO:00346131600.036
regulation of transcription from rna polymerase ii promoterGO:00063573780.036
protein complex biogenesisGO:00702712010.036
negative regulation of cell differentiationGO:00455961430.035
rrna processingGO:000636430.035
embryo development ending in birth or egg hatchingGO:00097921520.035
Worm
positive regulation of cell projection organizationGO:0031346290.035
kidney developmentGO:000182230.034
peptidyl tyrosine phosphorylationGO:0018108240.034
somatic stem cell maintenanceGO:0035019140.034
positive regulation of phosphorylationGO:0042327870.034
nucleotide metabolic processGO:00091171610.034
organic cyclic compound catabolic processGO:19013611680.034
small gtpase mediated signal transductionGO:0007264880.034
response to growth factorGO:0070848310.033
positive regulation of cellular component organizationGO:00511301560.033
immune system developmentGO:0002520570.032
regulation of cell cycle processGO:00105641810.032
regulation of mrna processingGO:0050684710.032
regulation of gtpase activityGO:0043087440.032
tissue morphogenesisGO:00487292970.032
intracellular protein transportGO:00068861040.032
morphogenesis of embryonic epitheliumGO:0016331940.032
chromosome organizationGO:00512763600.031
protein complex assemblyGO:00064612000.031
axon developmentGO:00615642970.031
regulation of cellular amino acid metabolic processGO:000652100.031
nucleoside phosphate metabolic processGO:00067531620.031
vesicle mediated transportGO:00161923810.031
cell proliferationGO:00082832990.031
regulation of molecular functionGO:00650092170.030
embryonic pattern specificationGO:00098801740.030
posttranscriptional regulation of gene expressionGO:00106081450.030
imaginal disc derived wing morphogenesisGO:00074763370.030
cellular response to chemical stimulusGO:00708871990.029
peptidyl tyrosine modificationGO:0018212240.029
defense responseGO:00069523000.028
protein localizationGO:00081042840.028
embryonic morphogenesisGO:00485982060.028
lateral inhibitionGO:00463312060.028
compound eye morphogenesisGO:00017452490.027
regulation of synapse assemblyGO:0051963940.027
posttranscriptional gene silencingGO:0016441460.027
positive regulation of mapk cascadeGO:0043410630.027
response to external biotic stimulusGO:00432072930.027
stem cell differentiationGO:00488631170.026
erk1 and erk2 cascadeGO:0070371390.026
glycosyl compound metabolic processGO:19016571270.026
purine nucleoside metabolic processGO:00422781270.026
cellular ketone metabolic processGO:0042180240.026
regulation of cell developmentGO:00602842150.026
signal releaseGO:0023061490.026
regulation of small gtpase mediated signal transductionGO:0051056930.025
rna splicing via transesterification reactionsGO:0000375730.025
positive regulation of protein phosphorylationGO:0001934340.025
single organism cellular localizationGO:19025801800.025
imaginal disc pattern formationGO:0007447910.024
regulation of apoptotic processGO:00429811300.024
wing disc pattern formationGO:0035222660.024
regulation of protein phosphorylationGO:0001932640.024
forebrain developmentGO:003090020.023
nerve developmentGO:002167560.023
regionalizationGO:00030024160.023
kidney morphogenesisGO:006099330.023
cardiovascular system developmentGO:0072358820.023
endocytosisGO:00068973100.023
organelle localizationGO:00516401480.023
negative regulation of signal transductionGO:00099682060.023
intracellular transportGO:00469072280.022
regulation of mrna metabolic processGO:1903311720.022
centrosome organizationGO:00512971630.022
purine nucleoside catabolic processGO:00061521120.022
regulation of gliogenesisGO:0014013110.022
positive regulation of ras protein signal transductionGO:0046579430.022
regulation of microtubule polymerization or depolymerizationGO:0031110270.022
nephron developmentGO:007200630.022
regulation of epithelial cell proliferationGO:005067840.022
organophosphate metabolic processGO:00196371950.022
guanosine containing compound metabolic processGO:1901068740.021
post embryonic hemopoiesisGO:0035166170.021
dendrite morphogenesisGO:00488131990.021
protein transportGO:00150311550.021
anterior posterior axis specification embryoGO:00085951030.021
protein polymerizationGO:0051258420.021
axonogenesisGO:00074092900.021
regulation of neuron differentiationGO:00456641030.020
cell cycle phase transitionGO:00447701400.020
single organism intracellular transportGO:19025822070.020
positive regulation of protein modification processGO:0031401580.020
compound eye developmentGO:00487493070.020
negative regulation of cellular response to growth factor stimulusGO:009028860.020
signal transduction in response to dna damageGO:004277030.020
mesenchymal cell developmentGO:001403110.020
mrna splicing via spliceosomeGO:0000398730.020
biological adhesionGO:00226101380.019
single organism behaviorGO:00447083910.019
signal transduction by phosphorylationGO:00230141070.019
organonitrogen compound catabolic processGO:19015651280.019
regulation of developmental growthGO:00486381740.019
regulation of stem cell differentiationGO:2000736140.019
cellular response to peptide hormone stimulusGO:0071375280.019
gastrulationGO:0007369700.019
oxoacid metabolic processGO:00434361030.018
positive regulation of growthGO:0045927750.018
regulation of peptidyl tyrosine phosphorylationGO:0050730100.018
glycosyl compound catabolic processGO:19016581120.018
ribonucleoside triphosphate metabolic processGO:00091991190.018
cellular macromolecule localizationGO:00707272200.018
regulation of cellular amine metabolic processGO:003323830.018
rubidium ion transportGO:003582610.018
positive regulation of small gtpase mediated signal transductionGO:0051057430.018
regulation of protein catabolic processGO:0042176550.018
negative regulation of biosynthetic processGO:00098902770.018
response to biotic stimulusGO:00096072940.018
stem cell maintenanceGO:0019827670.017
sister chromatid segregationGO:0000819920.017
regulation of cell divisionGO:0051302720.017
purine containing compound metabolic processGO:00725211550.017
establishment of protein localizationGO:00451841630.017
imaginal disc derived leg morphogenesisGO:0007480800.017
nucleoside triphosphate catabolic processGO:00091431080.017
homeostatic processGO:00425921990.017
positive regulation of cell cycle processGO:0090068280.017
positive regulation of multicellular organismal processGO:00512401430.017
regulation of epithelial cell differentiationGO:003085640.017
tube morphogenesisGO:00352391910.017
chromosome condensationGO:0030261410.016
imaginal disc derived appendage morphogenesisGO:00351143950.016
aromatic compound catabolic processGO:00194391660.016
nucleoside phosphate catabolic processGO:19012921100.016
stem cell developmentGO:0048864790.016
axis specificationGO:00097981670.016
regulation of mapk cascadeGO:0043408920.016
mitotic spindle organizationGO:00070522200.016
regulation of erk1 and erk2 cascadeGO:0070372390.016
positive regulation of cell deathGO:0010942690.016
epithelial cell differentiationGO:00308553220.016
maternal determination of anterior posterior axis embryoGO:0008358740.016
post embryonic appendage morphogenesisGO:00351203850.016
cytokinesisGO:0000910900.016
defense response to gram negative bacteriumGO:0050829940.016
response to organic substanceGO:00100332840.016
imaginal disc derived wing vein morphogenesisGO:0008586440.016
regulation of localizationGO:00328792750.016
regulation of phosphorylationGO:00423251470.016
cellular amino acid metabolic processGO:0006520610.016
regulation of neurogenesisGO:00507671580.016
regulation of organ formationGO:000315630.016
epithelial cell migrationGO:00106311480.015
regulation of nuclear divisionGO:0051783580.015
gland morphogenesisGO:00226121450.015
purine containing compound catabolic processGO:00725231120.015
positive regulation of programmed cell deathGO:0043068620.015
mitotic cell cycle phase transitionGO:00447721380.015
ribonucleoprotein complex biogenesisGO:0022613310.015
nucleobase containing compound catabolic processGO:00346551650.015
salivary gland developmentGO:00074311620.015
hindbrain developmentGO:003090220.015
vesicle targeting to from or within golgiGO:004819910.015
positive regulation of apoptotic processGO:0043065470.015
muscle structure developmentGO:00610612240.015
kidney epithelium developmentGO:007207330.015
renal system developmentGO:0072001720.015
wing disc dorsal ventral pattern formationGO:0048190470.015
ubiquitin dependent protein catabolic processGO:0006511780.015
positive regulation of organelle organizationGO:0010638650.015
renal tubule developmentGO:0061326640.015
digestive tract morphogenesisGO:00485461270.015
gene silencing by mirnaGO:0035195220.014
brain developmentGO:00074201200.014
regulation of protein modification processGO:00313991120.014
positive regulation of molecular functionGO:00440931360.014
sensory organ morphogenesisGO:00905962600.014
neural precursor cell proliferationGO:0061351750.014
digestive tract developmentGO:00485651490.014
proteolysis involved in cellular protein catabolic processGO:0051603830.014
response to bacteriumGO:00096171980.014
phagocytosisGO:00069092150.014
positive regulation of catabolic processGO:00098961050.014
gene silencing by rnaGO:0031047570.014
cellular protein complex disassemblyGO:0043624350.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
positive regulation of proteolysisGO:0045862520.014
positive regulation of exocytosisGO:004592140.014
cell cycle checkpointGO:0000075950.014
cellular macromolecular complex assemblyGO:00346221530.014
single organism membrane organizationGO:0044802930.014
regulation of synapse structure and activityGO:00508031280.014
neuronal stem cell maintenanceGO:009715040.014
response to extracellular stimulusGO:00099911160.014
regulation of hydrolase activityGO:0051336970.014
amine metabolic processGO:0009308120.014
larval behaviorGO:0030537420.014
positive regulation of stem cell differentiationGO:200073830.014
regulation of immune responseGO:00507761180.014
negative regulation of apoptotic processGO:0043066630.013
histone modificationGO:00165701060.013
single organism catabolic processGO:00447122280.013
positive regulation of notch signaling pathwayGO:0045747340.013
regulation of cell maturationGO:1903429270.013
maintenance of locationGO:0051235730.013
morphogenesis of an epitheliumGO:00020092760.013
endosomal transportGO:0016197440.013
nucleoside metabolic processGO:00091161270.013
protein modification by small protein conjugation or removalGO:00706471060.013
leg disc morphogenesisGO:0007478800.013
organic acid metabolic processGO:00060821030.013
cellular response to dna damage stimulusGO:00069742230.013
neurological system processGO:00508773580.013
columnar cuboidal epithelial cell differentiationGO:00020652560.013
protein targeting to nucleusGO:0044744510.013
imaginal disc derived leg joint morphogenesisGO:0016348150.013
production of molecular mediator of immune responseGO:0002440460.013
positive regulation of jun kinase activityGO:004350740.012
positive regulation of cytoskeleton organizationGO:0051495210.012
regulation of cellular catabolic processGO:00313291570.012
establishment of localization in cellGO:00516494020.012
embryonic hemopoiesisGO:0035162260.012
stem cell proliferationGO:0072089880.012
purine ribonucleoside metabolic processGO:00461281270.012
regulation of cellular response to growth factor stimulusGO:0090287130.012
ribonucleotide metabolic processGO:00092591450.012
anatomical structure homeostasisGO:0060249970.012
negative regulation of phosphate metabolic processGO:0045936450.012
columnar cuboidal epithelial cell developmentGO:00020662490.012
cellular homeostasisGO:0019725800.012
regulation of protein polymerizationGO:0032271280.012
regulation of hemocyte proliferationGO:0035206370.012
eye morphogenesisGO:00485922600.012
endomembrane system organizationGO:00102561190.012
negative regulation of response to external stimulusGO:0032102220.012
antimicrobial humoral responseGO:0019730990.012
cell maturationGO:00484691440.012
regulation of nucleotide catabolic processGO:0030811480.011
cell adhesionGO:00071551360.011
organophosphate catabolic processGO:00464341120.011
mushroom body developmentGO:0016319700.011
establishment of organelle localizationGO:00516561220.011
peptidyl amino acid modificationGO:00181931050.011
reproductive behaviorGO:00190981220.011
dna metabolic processGO:00062592270.011
nucleotide catabolic processGO:00091661090.011
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.011
regulation of secretionGO:0051046440.011
intracellular protein transmembrane transportGO:006500240.011
carbohydrate metabolic processGO:0005975820.011
regulation of heart morphogenesisGO:200082630.011
regulation of reproductive processGO:2000241540.011
regulation of cell proliferationGO:00421271630.011
positive regulation of protein complex assemblyGO:0031334220.011
glial cell proliferationGO:0014009130.011
purine ribonucleoside triphosphate metabolic processGO:00092051190.011
phosphatidylinositol mediated signalingGO:004801540.011
transforming growth factor beta receptor signaling pathwayGO:0007179160.011
regulation of cytoskeleton organizationGO:0051493890.011
adipose tissue developmentGO:006061220.011
organic substance transportGO:00717022570.010
actin cytoskeleton reorganizationGO:0031532220.010
regulation of cellular response to stressGO:0080135890.010
regulation of bindingGO:0051098160.010
outflow tract morphogenesisGO:000315140.010
nuclear transportGO:0051169720.010
positive regulation of erk1 and erk2 cascadeGO:0070374360.010
dna integrity checkpointGO:0031570810.010
muscle cell differentiationGO:00426921030.010

hrg disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.078
disease of cellular proliferationDOID:1456600.051
cancerDOID:16200.051
organ system cancerDOID:005068600.015
nervous system diseaseDOID:86300.012