Drosophila melanogaster

89 known processes

Nup214 (Dmel_CG3820)

Nucleoporin 214

(Aliases: l(2)10444,DNup214,DCAN,dCAN,CAN/Nup214,CAN,CG3820,nup214,Dmel\CG3820,Nup 214)

Nup214 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
smad protein import into nucleusGO:0007184110.782
negative regulation of gene expressionGO:00106293870.494
positive regulation of nucleic acid templated transcriptionGO:19035082660.410
Fly
positive regulation of gene expressionGO:00106282900.398
Fly
positive regulation of transcription dna templatedGO:00458932660.376
Fly
nuclear transportGO:0051169720.375
intracellular protein transportGO:00068861040.368
cell proliferationGO:00082832990.354
single organism nuclear importGO:1902593510.310
nucleus organizationGO:0006997450.304
positive regulation of rna biosynthetic processGO:19026802660.284
Fly
nucleocytoplasmic transportGO:0006913720.278
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.276
negative regulation of mitotic cell cycle phase transitionGO:19019911030.267
transcription from rna polymerase ii promoterGO:00063663680.240
Fly
protein importGO:0017038550.238
protein import into nucleusGO:0006606510.218
positive regulation of macromolecule biosynthetic processGO:00105572830.200
Fly
negative regulation of cell cycle phase transitionGO:19019881030.191
protein localization to nucleusGO:0034504550.187
negative regulation of macromolecule biosynthetic processGO:00105582700.170
cellular macromolecule localizationGO:00707272200.163
catabolic processGO:00090564090.139
cell cycle checkpointGO:0000075950.138
vesicle mediated transportGO:00161923810.132
positive regulation of macromolecule metabolic processGO:00106044050.131
Fly
macromolecular complex assemblyGO:00650032560.123
single organism cellular localizationGO:19025801800.122
protein targeting to nucleusGO:0044744510.121
rna localizationGO:00064031150.118
mitotic cell cycle checkpointGO:0007093880.118
mrna metabolic processGO:00160711240.104
chromatin organizationGO:00063252070.102
Fly
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.100
Fly
protein complex biogenesisGO:00702712010.096
positive regulation of biosynthetic processGO:00098913160.095
Fly
positive regulation of response to stimulusGO:00485843230.086
positive regulation of rna metabolic processGO:00512542710.085
Fly
gene silencingGO:00164581380.083
protein targetingGO:0006605640.080
regulation of mitotic cell cycle phase transitionGO:19019901300.080
translationGO:0006412690.076
macromolecule catabolic processGO:00090571610.076
protein transportGO:00150311550.074
negative regulation of cell cycleGO:00457861160.074
multi organism reproductive behaviorGO:00447051210.071
phagocytosisGO:00069092150.071
lateral inhibitionGO:00463312060.071
negative regulation of cell cycle processGO:00109481090.070
mitotic g2 dna damage checkpointGO:0007095690.070
protein localizationGO:00081042840.070
g2 dna damage checkpointGO:0031572690.069
reproductive structure developmentGO:0048608740.068
cytoplasmic transportGO:00164821300.067
chromatin modificationGO:00165681470.066
Fly
establishment of localization in cellGO:00516494020.065
cellular protein modification processGO:00064644380.061
organic substance transportGO:00717022570.061
response to light stimulusGO:00094161240.061
regulation of transcription from rna polymerase ii promoterGO:00063573780.060
Fly
protein localization to organelleGO:0033365820.059
cellular protein localizationGO:00346131600.058
protein complex assemblyGO:00064612000.058
establishment of protein localizationGO:00451841630.058
negative regulation of biosynthetic processGO:00098902770.057
positive regulation of nucleobase containing compound metabolic processGO:00459353320.057
Fly
developmental growthGO:00485892800.056
positive regulation of signalingGO:00230562430.055
multi multicellular organism processGO:00447061230.054
regulation of mitotic cell cycleGO:00073461900.054
rna processingGO:00063961470.053
chromatin assembly or disassemblyGO:0006333520.052
nls bearing protein import into nucleusGO:000660750.052
Fly
embryo development ending in birth or egg hatchingGO:00097921520.051
protein modification processGO:00362114380.051
ubiquitin dependent protein catabolic processGO:0006511780.051
regulation of cellular protein metabolic processGO:00322682430.051
mrna processingGO:00063971040.050
body morphogenesisGO:001017120.050
negative regulation of signal transductionGO:00099682060.049
agingGO:00075681430.048
nuclear importGO:0051170510.047
regulation of cell differentiationGO:00455953020.047
cellular macromolecule catabolic processGO:00442651360.046
endocytosisGO:00068973100.045
growthGO:00400073590.045
organic substance catabolic processGO:19015753080.043
imaginal disc derived appendage developmentGO:00487373990.043
positive regulation of cellular biosynthetic processGO:00313283160.041
Fly
gonad developmentGO:0008406500.040
reproductive behaviorGO:00190981220.040
regulation of protein metabolic processGO:00512462560.040
cellular catabolic processGO:00442483720.039
organonitrogen compound metabolic processGO:19015643180.039
response to organic substanceGO:00100332840.039
intracellular transportGO:00469072280.039
cell motilityGO:00488702510.039
head developmentGO:00603221350.038
positive regulation of signal transductionGO:00099672230.037
regulation of cell cycleGO:00517262910.036
negative regulation of cellular biosynthetic processGO:00313272770.036
connective tissue developmentGO:006144830.035
regulation of intracellular signal transductionGO:19025312360.035
reproductive system developmentGO:0061458740.034
mitotic dna damage checkpointGO:0044773740.034
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.034
regulation of chromatin modificationGO:1903308280.034
appendage morphogenesisGO:00351073970.033
apoptotic processGO:00069151590.033
determination of adult lifespanGO:00083401370.033
multicellular organismal agingGO:00102591400.032
heterocycle catabolic processGO:00467001660.032
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.032
cell migrationGO:00164772380.031
histone modificationGO:00165701060.031
cell deathGO:00082192790.031
positive regulation of intracellular signal transductionGO:19025331160.031
posttranscriptional regulation of gene expressionGO:00106081450.031
rna transportGO:0050658460.031
appendage developmentGO:00487364010.030
negative regulation of rna biosynthetic processGO:19026792400.030
sex differentiationGO:0007548810.029
multi organism behaviorGO:00517051750.029
imaginal disc derived appendage morphogenesisGO:00351143950.029
multicellular organismal reproductive behaviorGO:00330571100.029
positive regulation of nitrogen compound metabolic processGO:00511733540.028
Fly
response to other organismGO:00517072930.028
establishment of protein localization to organelleGO:0072594620.028
single organism intracellular transportGO:19025822070.028
enzyme linked receptor protein signaling pathwayGO:00071671790.027
regulation of cellular component biogenesisGO:00440872010.027
regulation of cell developmentGO:00602842150.027
regulation of cytoplasmic transportGO:1903649470.027
regulation of growthGO:00400082330.026
mitotic spindle organizationGO:00070522200.026
negative regulation of cellular metabolic processGO:00313243820.025
negative regulation of translationGO:0017148280.025
spindle organizationGO:00070512530.025
protein alkylationGO:0008213430.024
negative regulation of transcription dna templatedGO:00458922370.024
negative regulation of mitotic cell cycleGO:00459301090.024
regulation of gene expression epigeneticGO:00400291280.024
regulation of cellular amino acid metabolic processGO:000652100.024
mitotic cell cycle phase transitionGO:00447721380.024
imaginal disc derived wing morphogenesisGO:00074763370.024
dna integrity checkpointGO:0031570810.024
mitotic sister chromatid segregationGO:0000070870.023
negative regulation of protein metabolic processGO:0051248850.022
sister chromatid segregationGO:0000819920.022
macromolecular complex disassemblyGO:0032984370.021
central nervous system developmentGO:00074172010.021
mitotic nuclear divisionGO:00070672130.021
mitotic dna integrity checkpointGO:0044774750.021
single organism biosynthetic processGO:00447112060.020
regulation of proteolysisGO:0030162870.020
nuclear pore organizationGO:000699910.020
Fly
mitotic g2 m transition checkpointGO:0044818700.020
response to biotic stimulusGO:00096072940.019
mrna catabolic processGO:0006402330.019
rna splicingGO:0008380830.019
larval developmentGO:00021641040.019
negative regulation of cellular component organizationGO:00511291080.019
brain developmentGO:00074201200.019
cellular amino acid metabolic processGO:0006520610.018
aromatic compound catabolic processGO:00194391660.018
cellular ketone metabolic processGO:0042180240.018
post embryonic appendage morphogenesisGO:00351203850.018
modification dependent macromolecule catabolic processGO:0043632790.018
wing disc morphogenesisGO:00074723440.018
nitrogen compound transportGO:0071705850.017
establishment of rna localizationGO:0051236470.017
ribonucleoprotein complex subunit organizationGO:0071826280.017
negative regulation of cell proliferationGO:0008285690.017
homeostatic processGO:00425921990.017
histone acetylationGO:0016573380.017
regulation of transportGO:00510491810.017
rna polyadenylationGO:0043631120.017
cellular response to dna damage stimulusGO:00069742230.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.017
cell cycle phase transitionGO:00447701400.016
protein maturationGO:0051604710.016
regulation of chromatin organizationGO:1902275320.016
response to nitrogen compoundGO:1901698900.016
nuclear divisionGO:00002803320.016
covalent chromatin modificationGO:00165691060.016
regulation of mrna processingGO:0050684710.016
regulation of phosphate metabolic processGO:00192202100.016
regulation of chromosome organizationGO:0033044640.015
regulation of neuron differentiationGO:00456641030.015
dna replicationGO:0006260480.015
regulation of protein transportGO:0051223570.015
establishment of nucleus localizationGO:0040023260.015
positive regulation of cell communicationGO:00106472500.014
regulation of alternative mrna splicing via spliceosomeGO:0000381600.014
chromosome segregationGO:00070591570.014
dendrite developmentGO:00163582040.014
anterior posterior pattern specificationGO:00099521360.014
protein phosphorylationGO:00064681690.014
cellular response to chemical stimulusGO:00708871990.014
protein methylationGO:0006479430.014
negative regulation of signalingGO:00230572190.014
cellular response to organic substanceGO:00713101320.014
response to oxygen containing compoundGO:19017002000.014
regulation of programmed cell deathGO:00430671520.014
regulation of cellular localizationGO:00603411360.014
rna catabolic processGO:0006401370.014
regulation of cell proliferationGO:00421271630.013
ribonucleoprotein complex assemblyGO:0022618230.013
regulation of cellular ketone metabolic processGO:001056530.013
negative regulation of cellular protein metabolic processGO:0032269850.013
peptidyl lysine modificationGO:0018205570.013
regulation of nervous system developmentGO:00519602480.013
organelle localizationGO:00516401480.013
regulation of cell cycle phase transitionGO:19019871300.013
negative regulation of rna metabolic processGO:00512532510.013
proteolysisGO:00065081920.013
wound healingGO:0042060750.013
regulation of organelle organizationGO:00330431960.013
negative regulation of cell communicationGO:00106482230.013
cellular nitrogen compound catabolic processGO:00442701650.013
negative regulation of apoptotic processGO:0043066630.013
chromosome organizationGO:00512763600.012
Fly
regulation of translationGO:0006417560.012
positive regulation of programmed cell deathGO:0043068620.012
positive regulation of protein modification processGO:0031401580.012
dna metabolic processGO:00062592270.012
chromosome condensationGO:0030261410.012
regulation of neurogenesisGO:00507671580.012
regulation of protein catabolic processGO:0042176550.012
nucleobase containing compound transportGO:0015931560.012
phosphorylationGO:00163102940.012
dendrite morphogenesisGO:00488131990.012
response to endogenous stimulusGO:00097191190.011
axonogenesisGO:00074092900.011
cellular protein complex assemblyGO:0043623710.011
organic acid metabolic processGO:00060821030.011
chromatin remodelingGO:0006338720.011
Fly
imaginal disc derived leg morphogenesisGO:0007480800.011
response to lipopolysaccharideGO:003249640.011
regulation of transcription by chromatin organizationGO:003440130.011
Fly
negative regulation of cellular catabolic processGO:0031330340.011
regulation of multi organism processGO:00439001310.011
rna splicing via transesterification reactionsGO:0000375730.011
regulation of protein modification processGO:00313991120.011
intracellular signal transductionGO:00355563000.011
regulation of nucleocytoplasmic transportGO:0046822350.011
establishment of organelle localizationGO:00516561220.010
deathGO:00162652840.010
histone lysine demethylationGO:007007660.010
regulation of mrna splicing via spliceosomeGO:0048024640.010
nucleic acid transportGO:0050657460.010
blastoderm segmentationGO:00073501590.010
negative regulation of response to stimulusGO:00485852580.010
regulation of protein import into nucleusGO:0042306280.010
proteolysis involved in cellular protein catabolic processGO:0051603830.010

Nup214 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.032
disease of cellular proliferationDOID:1456600.014
nervous system diseaseDOID:86300.013
cancerDOID:16200.012
organ system cancerDOID:005068600.010
neurodegenerative diseaseDOID:128900.010
central nervous system diseaseDOID:33100.010