IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

Tps1 (Dmel_CG4104)

Trehalose-6-phosphate synthase 1

(Aliases: CG4104,CG4104 PA,l(2)jf4,l(2)jf5,l(2)k08903,l(2)24Ea,tps1,TPS,jf5,BcDNA:GH08860,TreS,Dmel\CG4104,dtps1)

FLYBASE: FBgn0027560
Entrez: 33642
UniProtKB: Q9Y119

Process Predictions
Disease Predictions

Tps1 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
single organism biosynthetic process	GO:0044711	206	0.773	Yeast
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.316
oxoacid metabolic process	GO:0043436	103	0.190
organic acid metabolic process	GO:0006082	103	0.183
small molecule biosynthetic process	GO:0044283	37	0.171
positive regulation of macromolecule metabolic process	GO:0010604	405	0.154
toxin metabolic process	GO:0009404	2	0.129
organic substance transport	GO:0071702	257	0.121
pigment metabolic process	GO:0042440	84	0.119
carboxylic acid metabolic process	GO:0019752	92	0.109
small molecule metabolic process	GO:0044281	305	0.107
cell division	GO:0051301	248	0.103
thioester metabolic process	GO:0035383	3	0.103
neurological system process	GO:0050877	358	0.099
cellular ketone metabolic process	GO:0042180	24	0.094
purine containing compound metabolic process	GO:0072521	155	0.092
anion homeostasis	GO:0055081	3	0.084
lateral inhibition	GO:0046331	206	0.083
response to glucose	GO:0009749	2	0.082
reproductive behavior	GO:0019098	122	0.082
chemical homeostasis	GO:0048878	92	0.079
homeostatic process	GO:0042592	199	0.078
response to abiotic stimulus	GO:0009628	341	0.073
purine ribonucleoside metabolic process	GO:0046128	127	0.072
single organism catabolic process	GO:0044712	228	0.071
sensory organ morphogenesis	GO:0090596	260	0.071
ribonucleoside metabolic process	GO:0009119	127	0.070
regulation of hormone levels	GO:0010817	40	0.069
response to oxygen containing compound	GO:1901700	200	0.067
purine nucleoside metabolic process	GO:0042278	127	0.066
protein acetylation	GO:0006473	39	0.066
eye development	GO:0001654	323	0.065
monocarboxylic acid metabolic process	GO:0032787	29	0.064
nucleoside metabolic process	GO:0009116	127	0.064
cell proliferation	GO:0008283	299	0.064
single organism behavior	GO:0044708	391	0.061
nitrogen compound transport	GO:0071705	85	0.060
cellular hormone metabolic process	GO:0034754	23	0.056
imaginal disc derived appendage development	GO:0048737	399	0.054
eye morphogenesis	GO:0048592	260	0.054
transmembrane receptor protein tyrosine kinase signaling pathway	GO:0007169	116	0.054
response to lipid	GO:0033993	38	0.053
secondary metabolic process	GO:0019748	75	0.053
positive regulation of signaling	GO:0023056	243	0.053
fat soluble vitamin metabolic process	GO:0006775	1	0.052
cellular response to chemical stimulus	GO:0070887	199	0.050
cellular macromolecule localization	GO:0070727	220	0.049
steroid metabolic process	GO:0008202	20	0.048
signal release	GO:0023061	49	0.048
response to temperature stimulus	GO:0009266	106	0.048
response to nitrogen compound	GO:1901698	90	0.047
catabolic process	GO:0009056	409	0.046
cellular amino acid metabolic process	GO:0006520	61	0.045
protein modification process	GO:0036211	438	0.045
organic substance catabolic process	GO:1901575	308	0.044
cellular catabolic process	GO:0044248	372	0.044
regulation of growth	GO:0040008	233	0.044
response to organic substance	GO:0010033	284	0.044
determination of adult lifespan	GO:0008340	137	0.043
positive regulation of gene expression	GO:0010628	290	0.042
regulation of cellular localization	GO:0060341	136	0.042
organelle fission	GO:0048285	340	0.041
carbohydrate derivative metabolic process	GO:1901135	217	0.041
cellular ion homeostasis	GO:0006873	39	0.040
organonitrogen compound metabolic process	GO:1901564	318	0.039
wing disc morphogenesis	GO:0007472	344	0.039
exocrine system development	GO:0035272	162	0.038
cellular protein modification process	GO:0006464	438	0.038
germ line cyst formation	GO:0048134	44	0.037
appendage morphogenesis	GO:0035107	397	0.037
regionalization	GO:0003002	416	0.037
positive regulation of response to stimulus	GO:0048584	323	0.037
regulation of localization	GO:0032879	275	0.037
glycosyl compound metabolic process	GO:1901657	127	0.036
positive regulation of cell communication	GO:0010647	250	0.036
developmental growth	GO:0048589	280	0.036
cellular nitrogen compound catabolic process	GO:0044270	165	0.034
multi organism behavior	GO:0051705	175	0.034
defense response	GO:0006952	300	0.033
response to endogenous stimulus	GO:0009719	119	0.033
post embryonic appendage morphogenesis	GO:0035120	385	0.033
establishment of localization in cell	GO:0051649	402	0.033
multi organism reproductive behavior	GO:0044705	121	0.033
ommochrome biosynthetic process	GO:0006727	19	0.031
response to organonitrogen compound	GO:0010243	75	0.031
medium chain fatty acid metabolic process	GO:0051791	1	0.031
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.031
secretion by cell	GO:0032940	101	0.029
macromolecular complex assembly	GO:0065003	256	0.029
intracellular transport	GO:0046907	228	0.029
nuclear division	GO:0000280	332	0.029
regulation of developmental growth	GO:0048638	174	0.028
cell death	GO:0008219	279	0.028
lipid homeostasis	GO:0055088	33	0.028
imaginal disc derived wing morphogenesis	GO:0007476	337	0.028
appendage development	GO:0048736	401	0.028
carbohydrate metabolic process	GO:0005975	82	0.026	Yeast
sulfur compound metabolic process	GO:0006790	59	0.026
death	GO:0016265	284	0.026
transmembrane transport	GO:0055085	139	0.025
cellular homeostasis	GO:0019725	80	0.025
cell recognition	GO:0008037	102	0.025
water homeostasis	GO:0030104	3	0.025
positive regulation of multicellular organismal process	GO:0051240	143	0.025
sensory perception	GO:0007600	196	0.025
ketone biosynthetic process	GO:0042181	16	0.025
response to alkaloid	GO:0043279	26	0.024
meiosis i	GO:0007127	59	0.024
developmental programmed cell death	GO:0010623	138	0.024
endocytosis	GO:0006897	310	0.024
multi multicellular organism process	GO:0044706	123	0.024
female germ line cyst formation	GO:0048135	42	0.024
innate immune response	GO:0045087	144	0.023
response to nutrient levels	GO:0031667	114	0.023
cell cycle phase transition	GO:0044770	140	0.023
secondary metabolite biosynthetic process	GO:0044550	24	0.022
neuron recognition	GO:0008038	101	0.022
immune response	GO:0006955	246	0.022
ocellus pigment biosynthetic process	GO:0008055	19	0.021
nucleotide metabolic process	GO:0009117	161	0.021
mitotic nuclear division	GO:0007067	213	0.021
eye pigment biosynthetic process	GO:0006726	32	0.021
positive regulation of biosynthetic process	GO:0009891	316	0.021
regulation of anatomical structure size	GO:0090066	163	0.021
regulation of behavior	GO:0050795	75	0.020
positive regulation of cell migration	GO:0030335	2	0.020
cell migration	GO:0016477	238	0.020
negative regulation of biosynthetic process	GO:0009890	277	0.020
germarium derived female germ line cyst formation	GO:0030727	42	0.020
cellular response to hexose stimulus	GO:0071331	1	0.020
regulation of cell death	GO:0010941	173	0.019
organonitrogen compound catabolic process	GO:1901565	128	0.019
establishment of protein localization	GO:0045184	163	0.019
positive regulation of transport	GO:0051050	92	0.018
camera type eye development	GO:0043010	4	0.018
steroid catabolic process	GO:0006706	1	0.018
sterol homeostasis	GO:0055092	4	0.018
ocellus pigmentation	GO:0033060	19	0.018
histolysis	GO:0007559	102	0.018
cognition	GO:0050890	141	0.018
intracellular signal transduction	GO:0035556	300	0.018
fatty acid metabolic process	GO:0006631	20	0.018
defense response to other organism	GO:0098542	225	0.018
single organism intracellular transport	GO:1902582	207	0.018
programmed cell death	GO:0012501	257	0.018
transcription from rna polymerase ii promoter	GO:0006366	368	0.017
multicellular organismal aging	GO:0010259	140	0.017
regulation of secretion	GO:0051046	44	0.017
insecticide catabolic process	GO:0046701	1	0.017
regulation of secretion by cell	GO:1903530	39	0.017
aging	GO:0007568	143	0.017
alpha amino acid metabolic process	GO:1901605	20	0.017
epithelial cell differentiation	GO:0030855	322	0.017
positive regulation of lipid metabolic process	GO:0045834	4	0.017
ocellus pigment metabolic process	GO:0046158	19	0.017
polyol biosynthetic process	GO:0046173	3	0.016
eye pigmentation	GO:0048069	43	0.016
compound eye morphogenesis	GO:0001745	249	0.016
response to hexose	GO:0009746	3	0.016
response to extracellular stimulus	GO:0009991	116	0.016
ion transport	GO:0006811	145	0.016
regulation of transport	GO:0051049	181	0.016
growth	GO:0040007	359	0.016
regulation of cellular component biogenesis	GO:0044087	201	0.016
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.016
protein localization	GO:0008104	284	0.016
ameboidal type cell migration	GO:0001667	151	0.016
cellular protein localization	GO:0034613	160	0.016
phagocytosis	GO:0006909	215	0.015
organic hydroxy compound metabolic process	GO:1901615	83	0.015
organic cyclic compound catabolic process	GO:1901361	168	0.015
stress activated protein kinase signaling cascade	GO:0031098	55	0.015
aromatic amino acid family metabolic process	GO:0009072	3	0.015
nucleobase containing small molecule metabolic process	GO:0055086	174	0.015
regulation of anatomical structure morphogenesis	GO:0022603	242	0.015
positive regulation of cellular amine metabolic process	GO:0033240	0	0.014
cellular macromolecule catabolic process	GO:0044265	136	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.014
dna metabolic process	GO:0006259	227	0.014
sensory perception of chemical stimulus	GO:0007606	116	0.014
compound eye development	GO:0048749	307	0.014
immune response activating signal transduction	GO:0002757	2	0.014
nucleoside catabolic process	GO:0009164	112	0.014
actin filament based process	GO:0030029	220	0.014
meiotic cell cycle	GO:0051321	171	0.014
chromatin modification	GO:0016568	147	0.014
ecdysteroid biosynthetic process	GO:0045456	15	0.014
gliogenesis	GO:0042063	80	0.014
covalent chromatin modification	GO:0016569	106	0.014
cell motility	GO:0048870	251	0.014
negative regulation of cellular metabolic process	GO:0031324	382	0.014
nucleoside phosphate metabolic process	GO:0006753	162	0.013
macromolecule catabolic process	GO:0009057	161	0.013
mitotic cytokinesis	GO:0000281	50	0.013
renal system process	GO:0003014	12	0.013
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.013
immune response regulating signaling pathway	GO:0002764	2	0.013
steroid biosynthetic process	GO:0006694	16	0.013
germarium derived egg chamber formation	GO:0007293	101	0.013
taxis	GO:0042330	304	0.013
response to biotic stimulus	GO:0009607	294	0.013
negative regulation of cellular component organization	GO:0051129	108	0.013
embryo development ending in birth or egg hatching	GO:0009792	152	0.013
cellular response to extracellular stimulus	GO:0031668	64	0.013
internal protein amino acid acetylation	GO:0006475	38	0.013
positive regulation of cellular catabolic process	GO:0031331	95	0.012
pigment metabolic process involved in pigmentation	GO:0043474	33	0.012
localization of cell	GO:0051674	257	0.012
chromosome organization	GO:0051276	360	0.012
regulation of phosphatase activity	GO:0010921	3	0.012
negative regulation of signal transduction	GO:0009968	206	0.012
purine nucleotide metabolic process	GO:0006163	146	0.012
cardiovascular system development	GO:0072358	82	0.012
locomotory behavior	GO:0007626	176	0.012
blastoderm segmentation	GO:0007350	159	0.012
lipid metabolic process	GO:0006629	121	0.012
hormone biosynthetic process	GO:0042446	20	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
positive regulation of catalytic activity	GO:0043085	118	0.012
multicellular organismal reproductive behavior	GO:0033057	110	0.012
purine ribonucleoside catabolic process	GO:0046130	112	0.012
protein acylation	GO:0043543	42	0.012
vesicle mediated transport	GO:0016192	381	0.012
response to organic cyclic compound	GO:0014070	89	0.012
chemotaxis	GO:0006935	249	0.012
developmental maturation	GO:0021700	172	0.011
cellular response to external stimulus	GO:0071496	66	0.011
tyrosine metabolic process	GO:0006570	1	0.011
rrna processing	GO:0006364	3	0.011
negative regulation of cell cycle	GO:0045786	116	0.011
vitamin metabolic process	GO:0006766	2	0.011
regulation of intracellular signal transduction	GO:1902531	236	0.011
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
meiotic nuclear division	GO:0007126	151	0.011
actin cytoskeleton organization	GO:0030036	206	0.011
tissue death	GO:0016271	102	0.011
cell growth	GO:0016049	108	0.011
regulation of cell cycle	GO:0051726	291	0.011
regulation of organelle organization	GO:0033043	196	0.011
organic hydroxy compound biosynthetic process	GO:1901617	21	0.011
salivary gland development	GO:0007431	162	0.011
immune effector process	GO:0002252	98	0.011
gland morphogenesis	GO:0022612	145	0.011
nucleobase containing compound catabolic process	GO:0034655	165	0.011
stress activated mapk cascade	GO:0051403	52	0.011
carbohydrate derivative catabolic process	GO:1901136	118	0.011
cellular response to biotic stimulus	GO:0071216	4	0.011
cellular modified amino acid metabolic process	GO:0006575	45	0.011
cellular response to monosaccharide stimulus	GO:0071326	2	0.011
cellular response to carbohydrate stimulus	GO:0071322	4	0.011
secretion	GO:0046903	109	0.011
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.011
regulation of catabolic process	GO:0009894	170	0.011
sensory perception of smell	GO:0007608	80	0.011
gene silencing by rna	GO:0031047	57	0.010
regulation of cellular catabolic process	GO:0031329	157	0.010
phosphorylation	GO:0016310	294	0.010
developmental pigmentation	GO:0048066	68	0.010
regulation of vesicle mediated transport	GO:0060627	59	0.010
autophagic cell death	GO:0048102	83	0.010
protein transport	GO:0015031	155	0.010
glycerolipid catabolic process	GO:0046503	3	0.010
fat soluble vitamin biosynthetic process	GO:0042362	1	0.010
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.010
ecdysteroid metabolic process	GO:0045455	19	0.010
synaptic transmission	GO:0007268	288	0.010

Tps1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
vascular disease	DOID:178	0.171
disease of anatomical entity	DOID:7	0.171
cardiovascular system disease	DOID:1287	0.171
artery disease	DOID:0050828	0.024
disease of metabolism	DOID:0014667	0.013
acquired metabolic disease	DOID:0060158	0.013
glucose metabolism disease	DOID:4194	0.012
diabetes mellitus	DOID:9351	0.012
carbohydrate metabolism disease	DOID:0050013	0.012

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