Drosophila melanogaster

19 known processes

Aph-4 (Dmel_CG1462)

Alkaline phosphatase 4

(Aliases: pMY51,l(3)07028,AP,Aph,Dmel\CG1462,CG1462)

Aph-4 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
ion transportGO:00068111450.062
small molecule metabolic processGO:00442813050.054
l glutamate importGO:005193810.052
organic acid metabolic processGO:00060821030.052
regionalizationGO:00030024160.049
organonitrogen compound metabolic processGO:19015643180.048
single organism behaviorGO:00447083910.046
organic substance transportGO:00717022570.045
catabolic processGO:00090564090.041
neurological system processGO:00508773580.041
response to other organismGO:00517072930.041
Rat
endocytosisGO:00068973100.040
oxoacid metabolic processGO:00434361030.039
l amino acid importGO:004309220.039
establishment of localization in cellGO:00516494020.039
response to abiotic stimulusGO:00096283410.039
lateral inhibitionGO:00463312060.038
medium chain fatty acid metabolic processGO:005179110.038
cellular catabolic processGO:00442483720.037
carboxylic acid metabolic processGO:0019752920.036
cellular amino acid metabolic processGO:0006520610.035
dorsal ventral pattern formationGO:00099531330.035
response to lipopolysaccharideGO:003249640.035
Rat
sensory perceptionGO:00076001960.034
response to biotic stimulusGO:00096072940.034
Rat
hormone catabolic processGO:004244730.034
cell cell signaling involved in cell fate commitmentGO:00451682100.034
steroid catabolic processGO:000670610.034
vesicle mediated transportGO:00161923810.033
transmembrane transportGO:00550851390.033
body morphogenesisGO:001017120.032
single organism biosynthetic processGO:00447112060.032
cation transmembrane transportGO:0098655880.031
sodium dependent phosphate transportGO:004434120.031
ion transmembrane transportGO:00342201220.031
benzene containing compound metabolic processGO:004253730.031
positive regulation of response to stimulusGO:00485843230.030
response to organic substanceGO:00100332840.030
Human Rat Fly
xenobiotic catabolic processGO:004217810.030
camera type eye developmentGO:004301040.030
organic substance catabolic processGO:19015753080.030
single organism catabolic processGO:00447122280.029
response to oxygen containing compoundGO:19017002000.029
Human Rat
kidney developmentGO:000182230.029
negative regulation of response to stimulusGO:00485852580.028
metal ion transportGO:0030001740.028
defense responseGO:00069523000.028
appendage developmentGO:00487364010.028
forebrain developmentGO:003090020.027
response to monosaccharideGO:003428440.027
response to external biotic stimulusGO:00432072930.027
Rat
response to glucoseGO:000974920.027
transcription from rna polymerase ii promoterGO:00063663680.027
cation transportGO:00068121100.026
positive regulation of cell migrationGO:003033520.026
cellular protein modification processGO:00064644380.026
regulation of multicellular organismal developmentGO:20000264140.026
regulation of cellular ketone metabolic processGO:001056530.026
imaginal disc pattern formationGO:0007447910.026
regulation of response to stressGO:00801342000.026
phagocytosisGO:00069092150.026
lipid metabolic processGO:00066291210.026
protein modification processGO:00362114380.025
defense response to other organismGO:00985422250.025
negative regulation of cellular metabolic processGO:00313243820.025
imaginal disc derived appendage morphogenesisGO:00351143950.025
cellular response to dna damage stimulusGO:00069742230.025
imaginal disc derived appendage developmentGO:00487373990.025
compound eye developmentGO:00487493070.025
response to organophosphorusGO:004668320.025
sensory perception of chemical stimulusGO:00076061160.025
intracellular transportGO:00469072280.025
polyol biosynthetic processGO:004617330.025
immune system processGO:00023763470.025
regulation of cellular amine metabolic processGO:003323830.024
multi organism behaviorGO:00517051750.024
positive regulation of cell communicationGO:00106472500.024
response to endogenous stimulusGO:00097191190.024
Rat Fly
response to bacteriumGO:00096171980.024
Rat
secretionGO:00469031090.024
appendage morphogenesisGO:00351073970.024
positive regulation of cellular biosynthetic processGO:00313283160.024
post embryonic appendage morphogenesisGO:00351203850.024
organonitrogen compound biosynthetic processGO:19015661170.024
cellular ketone metabolic processGO:0042180240.023
response to hexoseGO:000974630.023
secondary metabolite catabolic processGO:009048710.023
positive regulation of cell motilityGO:200014730.023
fat soluble vitamin metabolic processGO:000677510.023
amine metabolic processGO:0009308120.023
wing disc morphogenesisGO:00074723440.023
estrogen metabolic processGO:000821010.023
cellular response to ethanolGO:007136140.023
eye developmentGO:00016543230.023
negative regulation of gene expressionGO:00106293870.023
protein transportGO:00150311550.023
regulation of cellular amino acid metabolic processGO:000652100.022
intracellular signal transductionGO:00355563000.022
imaginal disc derived wing morphogenesisGO:00074763370.022
nuclear divisionGO:00002803320.022
positive regulation of macromolecule metabolic processGO:00106044050.022
cell deathGO:00082192790.022
taxisGO:00423303040.022
immune responseGO:00069552460.022
immune response activating signal transductionGO:000275720.022
response to nitrogen compoundGO:1901698900.022
Fly
regulation of localizationGO:00328792750.022
telencephalon developmentGO:002153720.022
positive regulation of gene expressionGO:00106282900.022
connective tissue developmentGO:006144830.022
insecticide metabolic processGO:001714320.021
proteolysisGO:00065081920.021
cellular amine metabolic processGO:0044106120.021
regulation of cell cycleGO:00517262910.021
positive regulation of nucleic acid templated transcriptionGO:19035082660.021
positive regulation of nucleobase containing compound metabolic processGO:00459353320.021
carbohydrate derivative metabolic processGO:19011352170.021
organelle fissionGO:00482853400.021
protein localizationGO:00081042840.021
anion homeostasisGO:005508130.021
compound eye morphogenesisGO:00017452490.021
response to nutrient levelsGO:00316671140.021
Human
androgen metabolic processGO:000820910.021
negative regulation of signal transductionGO:00099682060.021
aromatic compound catabolic processGO:00194391660.021
single organism intracellular transportGO:19025822070.021
positive regulation of signalingGO:00230562430.020
epithelial cell developmentGO:00020642740.020
developmental growthGO:00485892800.020
regulation of transcription from rna polymerase ii promoterGO:00063573780.020
organelle assemblyGO:00709251980.020
chromosome organizationGO:00512763600.020
vitamin biosynthetic processGO:000911010.020
response to mercury ionGO:004668930.020
regulation of epithelial cell proliferationGO:005067840.020
enzyme linked receptor protein signaling pathwayGO:00071671790.020
positive regulation of nitrogen compound metabolic processGO:00511733540.020
mating behaviorGO:00076171060.020
sensory perception of smellGO:0007608800.019
positive regulation of signal transductionGO:00099672230.019
wing disc pattern formationGO:0035222660.019
toxin catabolic processGO:000940710.019
activation of innate immune responseGO:000221840.019
immune response regulating signaling pathwayGO:000276420.019
phosphorylationGO:00163102940.019
ethanolamine containing compound metabolic processGO:004243940.019
positive regulation of biosynthetic processGO:00098913160.019
heterocycle catabolic processGO:00467001660.019
potassium ion transportGO:0006813200.019
response to radiationGO:00093141550.019
macromolecular complex assemblyGO:00650032560.019
epithelial cell differentiationGO:00308553220.019
cellular response to monosaccharide stimulusGO:007132620.019
regulation of cell differentiationGO:00455953020.018
adult behaviorGO:00305341370.018
inorganic ion transmembrane transportGO:0098660730.018
negative regulation of signalingGO:00230572190.018
spindle organizationGO:00070512530.018
establishment of protein localizationGO:00451841630.018
inorganic cation transmembrane transportGO:0098662610.018
cellular response to hexose stimulusGO:007133110.018
toxin metabolic processGO:000940420.018
programmed cell deathGO:00125012570.018
negative regulation of cell communicationGO:00106482230.018
regulation of multi organism processGO:00439001310.018
open tracheal system developmentGO:00074242040.018
cellular macromolecule catabolic processGO:00442651360.018
organic cyclic compound catabolic processGO:19013611680.018
exocrine system developmentGO:00352721620.018
chaeta developmentGO:0022416970.018
sensory organ morphogenesisGO:00905962600.017
eye morphogenesisGO:00485922600.017
monovalent inorganic cation transportGO:0015672400.017
cellular response to chemical stimulusGO:00708871990.017
nucleobase containing compound catabolic processGO:00346551650.017
positive regulation of rna biosynthetic processGO:19026802660.017
somatic muscle developmentGO:0007525660.017
macromolecule catabolic processGO:00090571610.017
cellular response to carbohydrate stimulusGO:007132240.017
locomotory behaviorGO:00076261760.017
cellular nitrogen compound catabolic processGO:00442701650.017
photoreceptor cell differentiationGO:00465301700.017
chemotaxisGO:00069352490.017
positive regulation of macromolecule biosynthetic processGO:00105572830.017
respiratory system developmentGO:00605412130.017
defense response to bacteriumGO:00427421780.017
regulation of defense responseGO:00313471020.017
negative regulation of cellular biosynthetic processGO:00313272770.017
vitamin metabolic processGO:000676620.017
regulation of intracellular signal transductionGO:19025312360.017
positive regulation of cellular amine metabolic processGO:003324000.017
organophosphate metabolic processGO:00196371950.017
growthGO:00400073590.017
regulation of molecular functionGO:00650092170.017
homeostatic processGO:00425921990.017
mitotic nuclear divisionGO:00070672130.017
fat soluble vitamin biosynthetic processGO:004236210.017
hindbrain developmentGO:003090220.017
innate immune responseGO:00450871440.017
mesenchymal cell differentiationGO:004876210.016
deathGO:00162652840.016
insecticide catabolic processGO:004670110.016
carbohydrate metabolic processGO:0005975820.016
positive regulation of transcription dna templatedGO:00458932660.016
multi multicellular organism processGO:00447061230.016
gland morphogenesisGO:00226121450.016
acylglycerol biosynthetic processGO:004646320.016
nucleoside phosphate metabolic processGO:00067531620.016
neuron projection guidanceGO:00974852410.016
kidney epithelium developmentGO:007207330.016
secondary metabolic processGO:0019748750.016
regulation of cellular component biogenesisGO:00440872010.016
acylglycerol catabolic processGO:004646430.016
molting cycle chitin based cuticleGO:0007591560.016
retina development in camera type eyeGO:006004140.016
localization of cellGO:00516742570.016
columnar cuboidal epithelial cell developmentGO:00020662490.016
sterol homeostasisGO:005509240.016
salivary gland developmentGO:00074311620.016
cognitionGO:00508901410.016
cellular component assembly involved in morphogenesisGO:00109271510.016
kidney morphogenesisGO:006099330.016
positive regulation of rna metabolic processGO:00512542710.016
nucleobase containing small molecule metabolic processGO:00550861740.016
camera type eye morphogenesisGO:004859320.016
regulation of transportGO:00510491810.016
regulation of catalytic activityGO:00507901850.016
response to organonitrogen compoundGO:0010243750.016
Fly
drinking behaviorGO:004275620.016
nephron developmentGO:007200630.016
intracellular protein transmembrane transportGO:006500240.016
regulation of cellular protein metabolic processGO:00322682430.015
monocarboxylic acid transportGO:001571830.015
cell divisionGO:00513012480.015
response to alcoholGO:0097305950.015
Human
cellular lipid metabolic processGO:0044255830.015
negative regulation of nitrogen compound metabolic processGO:00511722650.015
nitrogen compound transportGO:0071705850.015
regulation of immune responseGO:00507761180.015
salivary gland morphogenesisGO:00074351450.015
antimicrobial humoral responseGO:0019730990.015
limb developmentGO:006017310.015
response to organic cyclic compoundGO:0014070890.015
Human Rat Fly
lauric acid metabolic processGO:004825210.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
negative regulation of nucleic acid templated transcriptionGO:19035072400.015
protein complex biogenesisGO:00702712010.015
intracellular protein transmembrane importGO:004474340.015
multicellular organismal agingGO:00102591400.015
developmental maturationGO:00217001720.015
embryonic development via the syncytial blastodermGO:00017001480.015
chromosome segregationGO:00070591570.015
oligosaccharide transportGO:001577220.015
negative regulation of developmental processGO:00510932010.015
nucleotide metabolic processGO:00091171610.015
regulation of phosphorus metabolic processGO:00511742100.015
positive regulation of apoptotic signaling pathwayGO:200123540.015
cell proliferationGO:00082832990.015
negative regulation of nucleobase containing compound metabolic processGO:00459342610.015
cellular macromolecule localizationGO:00707272200.015
small gtpase mediated signal transductionGO:0007264880.015
cytoplasmic transportGO:00164821300.015
peptide metabolic processGO:0006518800.015
nephron epithelium developmentGO:007200930.015
protein hydroxylationGO:001812610.015
matingGO:00076181200.015
ameboidal type cell migrationGO:00016671510.014
courtship behaviorGO:0007619680.014
actin filament based processGO:00300292200.014
single organism cellular localizationGO:19025801800.014
gland developmentGO:00487321910.014
regulation of i kappab kinase nf kappab signalingGO:004312220.014
dorsal ventral pattern formation imaginal discGO:0007450510.014
hematopoietic progenitor cell differentiationGO:000224410.014
eye photoreceptor cell differentiationGO:00017541450.014
cellular response to organic substanceGO:00713101320.014
positive regulation of cellular amino acid metabolic processGO:004576400.014
reproductive behaviorGO:00190981220.014
phosphatidylethanolamine metabolic processGO:004633710.014
single organism carbohydrate metabolic processGO:0044723720.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.014
developmental programmed cell deathGO:00106231380.014
mitotic spindle organizationGO:00070522200.014
negative regulation of biosynthetic processGO:00098902770.014
neurotransmitter metabolic processGO:004213320.014
pyridine containing compound metabolic processGO:007252430.014
response to copper ionGO:004668840.014
histolysisGO:00075591020.014
mesenchymal cell developmentGO:001403110.014
protein transmembrane transportGO:007180640.014
columnar cuboidal epithelial cell differentiationGO:00020652560.014
cellular macromolecular complex assemblyGO:00346221530.014
ovarian follicle cell developmentGO:00307072480.014
segmentationGO:00352822070.014
spermatogenesisGO:00072832000.014
axis specificationGO:00097981670.014
regulation of nervous system developmentGO:00519602480.014
extrinsic apoptotic signaling pathwayGO:009719110.014
cellular amide metabolic processGO:0043603800.014
nephron tubule developmentGO:007208030.014
detection of stimulus involved in sensory perceptionGO:0050906920.014
mitochondrion organizationGO:0007005650.014
pattern recognition receptor signaling pathwayGO:000222120.014
wing disc dorsal ventral pattern formationGO:0048190470.014
purine containing compound metabolic processGO:00725211550.014
regulation of phosphate metabolic processGO:00192202100.014
phosphate ion transportGO:000681740.014
protein complex assemblyGO:00064612000.014
limb morphogenesisGO:003510810.014
dendrite morphogenesisGO:00488131990.014
agingGO:00075681430.014
jak stat cascadeGO:0007259490.014
innate immune response activating signal transductionGO:000275820.014
morphogenesis of an epitheliumGO:00020092760.014
regulation of mitotic cell cycleGO:00073461900.014
ribonucleoside metabolic processGO:00091191270.014
cell cycle phase transitionGO:00447701400.014
regulation of cell developmentGO:00602842150.014
catecholamine biosynthetic processGO:004242330.014
nephron tubule morphogenesisGO:007207830.014
central nervous system developmentGO:00074172010.014
regulation of hormone levelsGO:0010817400.013
rna processingGO:00063961470.013
nucleoside triphosphate metabolic processGO:00091411200.013
male gamete generationGO:00482322010.013
actin cytoskeleton organizationGO:00300362060.013
cranial nerve developmentGO:002154510.013
actin filament organizationGO:00070151260.013
ras protein signal transductionGO:0007265880.013
nephron epithelium morphogenesisGO:007208830.013
memoryGO:0007613940.013
rna localizationGO:00064031150.013
cellular response to molecule of bacterial originGO:007121930.013
regulation of cell cycle processGO:00105641810.013
nucleoside metabolic processGO:00091161270.013
dendrite developmentGO:00163582040.013
multi organism reproductive behaviorGO:00447051210.013
cellular homeostasisGO:0019725800.013
determination of adult lifespanGO:00083401370.013
humoral immune responseGO:00069591170.013
chromatin remodelingGO:0006338720.013
regulation of cellular response to stressGO:0080135890.013
regulation of cell deathGO:00109411730.013
response to light stimulusGO:00094161240.013
purine nucleoside triphosphate metabolic processGO:00091441190.013
regulation of cellular localizationGO:00603411360.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
peptidyl proline hydroxylationGO:001951110.013
positive regulation of lipid metabolic processGO:004583440.013
axon guidanceGO:00074112330.013
purine nucleotide metabolic processGO:00061631460.013
tissue deathGO:00162711020.013
nephron morphogenesisGO:007202830.013
cell motilityGO:00488702510.013
positive regulation of transportGO:0051050920.013
negative regulation of macromolecule biosynthetic processGO:00105582700.013
ribonucleoside triphosphate metabolic processGO:00091991190.013
organonitrogen compound catabolic processGO:19015651280.013
cholesterol transportGO:003030120.013
wnt signaling pathwayGO:0016055980.013
proteolysis involved in cellular protein catabolic processGO:0051603830.013
multicellular organismal reproductive behaviorGO:00330571100.013
cellular response to lipopolysaccharideGO:007122230.013
peripheral nervous system developmentGO:0007422520.013
posttranscriptional regulation of gene expressionGO:00106081450.013
response to temperature stimulusGO:00092661060.013
protein secretionGO:0009306450.013
detection of chemical stimulusGO:0009593930.013
embryonic pattern specificationGO:00098801740.013
regulation of protein metabolic processGO:00512462560.013
compound eye photoreceptor cell differentiationGO:00017511400.013
carbohydrate derivative catabolic processGO:19011361180.013
pigment metabolic processGO:0042440840.013
anion transportGO:0006820410.013
dephosphorylationGO:0016311510.013
Human Rat
detection of stimulusGO:00516061560.013
triglyceride biosynthetic processGO:001943220.013
mrna metabolic processGO:00160711240.013
negative regulation of rna metabolic processGO:00512532510.013
embryonic morphogenesisGO:00485982060.013
negative regulation of rna biosynthetic processGO:19026792400.013
lipopolysaccharide mediated signaling pathwayGO:003166310.013
nucleoside triphosphate catabolic processGO:00091431080.013
biological adhesionGO:00226101380.013
photoreceptor cell developmentGO:0042461960.013
ribose phosphate metabolic processGO:00196931450.012
purine ribonucleoside metabolic processGO:00461281270.012
ribonucleotide metabolic processGO:00092591450.012
tissue morphogenesisGO:00487292970.012
purine ribonucleotide metabolic processGO:00091501450.012
meiotic dna double strand break formation involved in reciprocal meiotic recombinationGO:001078010.012
purine nucleoside triphosphate catabolic processGO:00091461080.012
apoptotic process involved in morphogenesisGO:006056130.012
mitotic cell cycle phase transitionGO:00447721380.012
membrane organizationGO:00610241120.012
glutathione metabolic processGO:0006749370.012
neuromuscular junction developmentGO:00075281490.012
pronuclear migrationGO:003504640.012
regulation of organelle organizationGO:00330431960.012
axonogenesisGO:00074092900.012
sensory perception of painGO:001923340.012
autophagic cell deathGO:0048102830.012
peptidyl threonine phosphorylationGO:001810720.012
cuticle developmentGO:0042335860.012
anatomical structure homeostasisGO:0060249970.012
purine nucleotide catabolic processGO:00061951090.012
ribonucleoside catabolic processGO:00424541120.012
spinal cord developmentGO:002151010.012
positive regulation of lipid storageGO:001088440.012
pigmentationGO:0043473750.012
nicotinamide nucleotide metabolic processGO:004649620.012
response to oxygen levelsGO:0070482590.012
regulation of steroid metabolic processGO:001921820.012
purine nucleoside metabolic processGO:00422781270.012
regulation of sequestering of triglycerideGO:001088930.012
salivary gland histolysisGO:0035070880.012
imaginal disc derived wing vein specificationGO:0007474480.012
nucleoside catabolic processGO:00091641120.012
mitotic g2 dna damage checkpointGO:0007095690.012
regulation of innate immune responseGO:0045088710.012
ribonucleotide catabolic processGO:00092611090.012
phospholipid homeostasisGO:005509110.012
response to paraquatGO:190156240.012
notch signaling pathwayGO:00072191200.012
regulation of catabolic processGO:00098941700.012
negative regulation of epithelial cell proliferationGO:005068040.012
mitotic g2 m transition checkpointGO:0044818700.012
regulation of immune system processGO:00026821760.012
cellularizationGO:0007349900.012
glutamine metabolic processGO:000654140.012
positive regulation of molecular functionGO:00440931360.012
transmembrane receptor protein serine threonine kinase signaling pathwayGO:0007178650.012
microtubule organizing center organizationGO:00310231680.012
ribonucleoside triphosphate catabolic processGO:00092031080.012
regulation of epithelial cell differentiationGO:003085640.012
nucleoside phosphate catabolic processGO:19012921100.012
positive regulation of catalytic activityGO:00430851180.012
blastoderm segmentationGO:00073501590.012
cell agingGO:000756920.012
nucleotide catabolic processGO:00091661090.012
regulation of programmed cell deathGO:00430671520.012
behavioral response to ethanolGO:0048149490.012
regulation of embryonic pattern specificationGO:1902875270.012
carbohydrate derivative biosynthetic processGO:1901137850.012
regulation of hydrolase activityGO:0051336970.012
purine ribonucleoside triphosphate catabolic processGO:00092071080.012
response to ethanolGO:0045471590.012
peptidyl proline modificationGO:001820830.012
axon developmentGO:00615642970.012
salivary gland cell autophagic cell deathGO:0035071830.012
regulation of pathway restricted smad protein phosphorylationGO:006039310.012
acetate ester metabolic processGO:190061920.012
cell projection assemblyGO:0030031940.012
wound healingGO:0042060750.012
regulation of cellular catabolic processGO:00313291570.012
regulation of anatomical structure morphogenesisGO:00226032420.012
cell migrationGO:00164772380.012
organophosphate catabolic processGO:00464341120.012
snrna 3 end processingGO:0034472140.012
endomembrane system organizationGO:00102561190.012
endoderm formationGO:000170630.012
neuropeptide signaling pathwayGO:0007218450.012
purine ribonucleotide catabolic processGO:00091541090.012
detection of chemical stimulus involved in sensory perceptionGO:0050907750.012
mitotic sister chromatid segregationGO:0000070870.012
cholesterol homeostasisGO:004263230.012
regulation of notch signaling pathwayGO:00085931000.012
positive regulation of intracellular signal transductionGO:19025331160.011
dorsal ventral axis specificationGO:0009950660.011
peptidyl amino acid modificationGO:00181931050.011

Aph-4 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.052
cardiovascular system diseaseDOID:128700.026
disease of metabolismDOID:001466700.026
hypophosphatasiaDOID:1421300.025
Human
inherited metabolic disorderDOID:65500.023
nervous system diseaseDOID:86300.021
vascular diseaseDOID:17800.019
essential hypertensionDOID:1082500.018
hypertensionDOID:1076300.018
artery diseaseDOID:005082800.018
disease of cellular proliferationDOID:1456600.018
cancerDOID:16200.017
diabetes mellitusDOID:935100.015
carbohydrate metabolism diseaseDOID:005001300.015
acquired metabolic diseaseDOID:006015800.015
glucose metabolism diseaseDOID:419400.015
type 2 diabetes mellitusDOID:935200.014
musculoskeletal system diseaseDOID:1700.014
organ system cancerDOID:005068600.014
urinary system diseaseDOID:1800.013
sensory system diseaseDOID:005015500.013
kidney diseaseDOID:55700.012
eye and adnexa diseaseDOID:149200.012
renal tubular transport diseaseDOID:44700.012
central nervous system diseaseDOID:33100.011