Drosophila melanogaster

142 known processes

Acsl (Dmel_CG8732)

Acyl-CoA synthetase long-chain

(Aliases: l(2)05847,FCS,CG8732,7447,l(2)k05304,dAcsl,l(2)44DEa,anon-WO0172774.173,l(2)7447,Dmel\CG8732)

Acsl biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of synaptic growth at neuromuscular junctionGO:0008582890.996
axon developmentGO:00615642970.995
synaptic growth at neuromuscular junctionGO:00511241190.987
regulation of synapse organizationGO:00508071100.985
synapse assemblyGO:00074161430.978
neuromuscular junction developmentGO:00075281490.973
synapse organizationGO:00508081960.941
positive regulation of synaptic growth at neuromuscular junctionGO:0045887260.919
regulation of nervous system developmentGO:00519602480.899
regulation of multicellular organismal developmentGO:20000264140.899
axonogenesisGO:00074092900.886
cell migrationGO:00164772380.877
regulation of synapse structure and activityGO:00508031280.836
growthGO:00400073590.798
establishment of localization in cellGO:00516494020.786
regulation of transcription from rna polymerase ii promoterGO:00063573780.755
regulation of synapse assemblyGO:0051963940.748
regulation of developmental growthGO:00486381740.662
positive regulation of gene expressionGO:00106282900.640
negative regulation of synaptic growth at neuromuscular junctionGO:0045886390.634
positive regulation of developmental processGO:00510941430.632
stem cell differentiationGO:00488631170.618
axon guidanceGO:00074112330.578
regulation of cellular component biogenesisGO:00440872010.530
lipid metabolic processGO:00066291210.506
Human Mouse
syncytium formationGO:0006949430.501
positive regulation of macromolecule metabolic processGO:00106044050.493
cell deathGO:00082192790.448
taxisGO:00423303040.445
localization of cellGO:00516742570.432
agingGO:00075681430.420
Worm
positive regulation of response to stimulusGO:00485843230.406
Zebrafish
epithelial cell differentiationGO:00308553220.394
multicellular organismal agingGO:00102591400.383
Worm
neuron projection guidanceGO:00974852410.374
response to unfolded proteinGO:000698690.371
cellular response to chemical stimulusGO:00708871990.349
ion transportGO:00068111450.344
Human
positive regulation of cellular component organizationGO:00511301560.343
positive regulation of macromolecule biosynthetic processGO:00105572830.342
determination of bilateral symmetryGO:0009855130.332
gastrulationGO:0007369700.330
cellular lipid metabolic processGO:0044255830.317
Human Mouse
locomotory behaviorGO:00076261760.312
regulation of cell developmentGO:00602842150.304
central nervous system developmentGO:00074172010.301
cell motilityGO:00488702510.265
organic substance transportGO:00717022570.254
Human
developmental growthGO:00485892800.239
response to oxygen containing compoundGO:19017002000.232
positive regulation of cellular biosynthetic processGO:00313283160.217
single organism intracellular transportGO:19025822070.214
embryonic morphogenesisGO:00485982060.206
positive regulation of cellular component biogenesisGO:0044089800.204
positive regulation of biosynthetic processGO:00098913160.199
deathGO:00162652840.196
intracellular transportGO:00469072280.193
brain developmentGO:00074201200.191
reproductive behaviorGO:00190981220.191
homeostatic processGO:00425921990.190
vesicle mediated transportGO:00161923810.190
regulation of cell differentiationGO:00455953020.183
heart developmentGO:0007507820.181
positive regulation of synapse assemblyGO:0051965290.178
endocytosisGO:00068973100.175
chemotaxisGO:00069352490.170
single organism behaviorGO:00447083910.164
positive regulation of multicellular organismal processGO:00512401430.152
urogenital system developmentGO:0001655720.150
detection of stimulus involved in sensory perceptionGO:0050906920.149
neuromuscular synaptic transmissionGO:0007274670.146
regulation of cell sizeGO:0008361630.145
transmembrane transportGO:00550851390.140
regulation of growthGO:00400082330.140
transcription from rna polymerase ii promoterGO:00063663680.140
regulation of cell deathGO:00109411730.136
response to biotic stimulusGO:00096072940.134
positive regulation of nucleic acid templated transcriptionGO:19035082660.133
dendrite developmentGO:00163582040.129
striated muscle myosin thick filament assemblyGO:007168830.125
negative regulation of developmental processGO:00510932010.125
negative regulation of cellular component organizationGO:00511291080.122
small molecule metabolic processGO:00442813050.117
Human Mouse
stem cell developmentGO:0048864790.116
organelle localizationGO:00516401480.113
appendage morphogenesisGO:00351073970.112
determination of adult lifespanGO:00083401370.110
Worm
positive regulation of signal transductionGO:00099672230.110
Zebrafish
protein localizationGO:00081042840.110
positive regulation of signalingGO:00230562430.108
Zebrafish
cellular catabolic processGO:00442483720.108
regionalizationGO:00030024160.107
negative regulation of developmental growthGO:0048640640.105
cell divisionGO:00513012480.105
oocyte maturationGO:000155630.102
positive regulation of axon extensionGO:004577320.100
organic acid metabolic processGO:00060821030.099
Human Mouse
regulation of anatomical structure morphogenesisGO:00226032420.098
post embryonic appendage morphogenesisGO:00351203850.096
negative regulation of gene expressionGO:00106293870.092
endomembrane system organizationGO:00102561190.092
regulation of organelle organizationGO:00330431960.091
epithelial cell developmentGO:00020642740.091
regulation of cell projection organizationGO:0031344920.091
monocarboxylic acid metabolic processGO:0032787290.090
Human Mouse
stem cell maintenanceGO:0019827670.090
spermatogenesisGO:00072832000.090
chromosome segregationGO:00070591570.089
cellular response to topologically incorrect proteinGO:0035967100.089
catabolic processGO:00090564090.087
response to external biotic stimulusGO:00432072930.086
tissue migrationGO:00901301550.084
oxoacid metabolic processGO:00434361030.084
Human Mouse
epithelial cell migrationGO:00106311480.083
germ line stem cell maintenanceGO:0030718500.081
positive regulation of cell communicationGO:00106472500.080
Zebrafish
membrane organizationGO:00610241120.080
proteolysisGO:00065081920.079
response to osmotic stressGO:0006970140.079
regulation of localizationGO:00328792750.079
establishment of protein localizationGO:00451841630.077
meiotic nuclear divisionGO:00071261510.075
organonitrogen compound metabolic processGO:19015643180.072
multi multicellular organism processGO:00447061230.072
Mouse
cellular response to organic substanceGO:00713101320.070
synaptic vesicle fusion to presynaptic membraneGO:003162970.069
segmentationGO:00352822070.068
germ cell migrationGO:0008354430.068
intracellular signal transductionGO:00355563000.068
Zebrafish
dendrite morphogenesisGO:00488131990.068
carboxylic acid metabolic processGO:0019752920.066
Human Mouse
ovarian follicle cell developmentGO:00307072480.066
male gamete generationGO:00482322010.065
regulation of anatomical structure sizeGO:00900661630.064
negative regulation of growthGO:0045926840.063
response to radiationGO:00093141550.063
positive regulation of rna biosynthetic processGO:19026802660.062
glycosyl compound metabolic processGO:19016571270.060
regulation of ion transmembrane transportGO:0034765270.060
regulation of neurogenesisGO:00507671580.056
forebrain developmentGO:003090020.056
anatomical structure homeostasisGO:0060249970.056
axon extensionGO:0048675320.055
appendage developmentGO:00487364010.055
multi organism reproductive behaviorGO:00447051210.054
head developmentGO:00603221350.052
myofibril assemblyGO:0030239360.052
purine ribonucleoside triphosphate metabolic processGO:00092051190.051
multicellular organismal reproductive behaviorGO:00330571100.051
positive regulation of nucleobase containing compound metabolic processGO:00459353320.049
cellular protein complex disassemblyGO:0043624350.049
regulation of cytoskeleton organizationGO:0051493890.049
purine nucleotide metabolic processGO:00061631460.048
cytoskeleton dependent intracellular transportGO:0030705440.048
regulation of protein complex disassemblyGO:0043244290.048
meiotic cell cycleGO:00513211710.047
negative regulation of organelle organizationGO:0010639560.047
ribonucleoside metabolic processGO:00091191270.047
cellular amine metabolic processGO:0044106120.047
regulation of actin polymerization or depolymerizationGO:0008064270.047
actin cytoskeleton organizationGO:00300362060.047
negative regulation of biosynthetic processGO:00098902770.047
negative regulation of cytoskeleton organizationGO:0051494300.046
ribonucleotide metabolic processGO:00092591450.046
endoderm formationGO:000170630.046
body morphogenesisGO:001017120.046
metal ion transportGO:0030001740.045
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.045
secretion by cellGO:00329401010.045
phagocytosisGO:00069092150.044
regulation of cellular ketone metabolic processGO:001056530.044
developmental growth involved in morphogenesisGO:0060560650.044
mitochondrion organizationGO:0007005650.043
programmed cell deathGO:00125012570.043
eye developmentGO:00016543230.043
imaginal disc derived appendage morphogenesisGO:00351143950.042
cellular macromolecular complex assemblyGO:00346221530.042
tube developmentGO:00352952440.042
glial cell differentiationGO:0010001350.041
regulation of neuron projection developmentGO:0010975690.041
organic substance catabolic processGO:19015753080.041
positive regulation of cell migrationGO:003033520.040
tripartite regional subdivisionGO:00073511030.040
regulation of neurotransmitter levelsGO:0001505380.040
cellular ketone metabolic processGO:0042180240.040
single organism catabolic processGO:00447122280.039
cation transportGO:00068121100.039
ameboidal type cell migrationGO:00016671510.038
positive regulation of transcription dna templatedGO:00458932660.037
purine ribonucleoside metabolic processGO:00461281270.037
cellular macromolecule localizationGO:00707272200.037
multi organism behaviorGO:00517051750.037
response to organic substanceGO:00100332840.037
negative regulation of synapse assemblyGO:0051964390.037
cellular protein localizationGO:00346131600.036
cellular response to abiotic stimulusGO:0071214580.036
positive regulation of nitrogen compound metabolic processGO:00511733540.036
embryo development ending in birth or egg hatchingGO:00097921520.036
Mouse Worm
regulation of programmed cell deathGO:00430671520.036
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.035
regulation of bmp signaling pathwayGO:0030510230.035
actin filament organizationGO:00070151260.035
positive regulation of developmental growthGO:0048639620.035
nucleoside phosphate metabolic processGO:00067531620.034
positive regulation of growthGO:0045927750.034
Human
organ growthGO:0035265560.034
response to abiotic stimulusGO:00096283410.034
camera type eye developmentGO:004301040.034
anterior posterior pattern specificationGO:00099521360.034
adult locomotory behaviorGO:0008344760.033
pole plasm protein localizationGO:0007318100.033
positive regulation of nervous system developmentGO:0051962690.033
actin mediated cell contractionGO:0070252210.033
cytokinetic cell separationGO:000092010.032
regulation of cell growthGO:0001558430.032
Human
detection of light stimulusGO:0009583580.032
neuron projection extensionGO:1990138320.032
anterior posterior axis specification embryoGO:00085951030.032
sex differentiationGO:0007548810.032
retina development in camera type eyeGO:006004140.031
telencephalon developmentGO:002153720.031
cell recognitionGO:00080371020.031
metal ion homeostasisGO:0055065440.031
synaptic transmissionGO:00072682880.031
regulation of system processGO:0044057360.031
neuron recognitionGO:00080381010.030
positive regulation of immune system processGO:0002684680.030
response to light stimulusGO:00094161240.030
morphogenesis of an epitheliumGO:00020092760.029
cellular component assembly involved in morphogenesisGO:00109271510.029
macromolecular complex disassemblyGO:0032984370.029
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.029
lateral inhibitionGO:00463312060.029
spermatid differentiationGO:00485151140.029
muscle structure developmentGO:00610612240.028
cation transmembrane transportGO:0098655880.027
cellular response to oxygen containing compoundGO:1901701790.027
negative regulation of nitrogen compound metabolic processGO:00511722650.027
columnar cuboidal epithelial cell developmentGO:00020662490.027
glial cell developmentGO:0021782270.027
regulation of pathway restricted smad protein phosphorylationGO:006039310.027
ion homeostasisGO:0050801550.027
circulatory system developmentGO:0072359820.027
positive regulation of locomotionGO:004001780.026
membrane tubulationGO:009732040.026
purine ribonucleoside catabolic processGO:00461301120.026
regulation of mitotic cell cycleGO:00073461900.026
protein targetingGO:0006605640.026
response to heatGO:0009408630.025
positive regulation of cellular catabolic processGO:0031331950.025
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.025
cell proliferationGO:00082832990.025
specification of symmetryGO:0009799130.025
single organism membrane organizationGO:0044802930.024
gliogenesisGO:0042063800.024
imaginal disc derived appendage developmentGO:00487373990.024
intracellular protein transportGO:00068861040.023
embryonic heart tube developmentGO:0035050220.023
regulation of transmembrane transportGO:0034762270.023
cellular response to nitrogen compoundGO:1901699510.023
positive regulation of intracellular signal transductionGO:19025331160.023
striated muscle cell differentiationGO:0051146900.023
regulation of behaviorGO:0050795750.023
developmental cell growthGO:0048588520.023
cardiovascular system developmentGO:0072358820.023
regulation of apoptotic signaling pathwayGO:2001233100.022
cytoskeleton dependent cytokinesisGO:0061640810.022
actin filament based processGO:00300292200.022
signal releaseGO:0023061490.022
single organism cellular localizationGO:19025801800.022
wnt signaling pathwayGO:0016055980.022
regulation of muscle cell differentiationGO:005114780.021
positive regulation of rna metabolic processGO:00512542710.021
regulation of intracellular signal transductionGO:19025312360.021
Zebrafish
meiotic cytokinesisGO:0033206330.021
negative regulation of bmp signaling pathwayGO:0030514120.021
embryonic pattern specificationGO:00098801740.021
negative regulation of nucleobase containing compound metabolic processGO:00459342610.021
purine ribonucleotide biosynthetic processGO:0009152280.020
inorganic cation transmembrane transportGO:0098662610.020
ovipositionGO:0018991190.020
nucleotide catabolic processGO:00091661090.020
organophosphate metabolic processGO:00196371950.020
decapentaplegic signaling pathwayGO:0008101190.020
organelle fissionGO:00482853400.020
positive regulation of cell motilityGO:200014730.020
oxidation reduction processGO:00551141230.019
response to woundingGO:0009611940.019
eye antennal disc morphogenesisGO:0007455340.019
apoptotic processGO:00069151590.019
regulation of actin filament polymerizationGO:0030833250.019
ribose phosphate metabolic processGO:00196931450.019
regulation of multicellular organism growthGO:0040014400.019
epithelial tube morphogenesisGO:0060562880.019
cellular protein modification processGO:00064644380.018
meiotic cell cycle processGO:19030461320.018
potassium ion transportGO:0006813200.018
trunk segmentationGO:003529080.018
carbohydrate derivative biosynthetic processGO:1901137850.018
atp metabolic processGO:0046034490.018
cytokinetic processGO:0032506270.018
regulation of transporter activityGO:003240960.018
cellular protein complex assemblyGO:0043623710.018
protein transportGO:00150311550.018
negative regulation of nervous system developmentGO:0051961920.018
tube morphogenesisGO:00352391910.018
negative regulation of macromolecule biosynthetic processGO:00105582700.018
cellular response to peptideGO:1901653280.018
negative regulation of cellular response to growth factor stimulusGO:009028860.017
positive regulation of phosphate metabolic processGO:00459371390.017
carbohydrate metabolic processGO:0005975820.017
development of primary sexual characteristicsGO:0045137500.017
skeletal muscle adaptationGO:004350110.017
nucleobase containing small molecule metabolic processGO:00550861740.017
carbohydrate derivative metabolic processGO:19011352170.017
multicellular organismal homeostasisGO:0048871410.017
cellular amino acid metabolic processGO:0006520610.017
regulation of cellular component sizeGO:0032535980.017
purine nucleoside metabolic processGO:00422781270.017
positive regulation of axonogenesisGO:005077220.017
response to alcoholGO:0097305950.017
response to endogenous stimulusGO:00097191190.017
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.017
monocarboxylic acid transportGO:001571830.016
Human
embryonic axis specificationGO:00005781070.016
peripheral nervous system developmentGO:0007422520.016
regulation of tube diameterGO:0035296140.016
regulation of neuron differentiationGO:00456641030.016
protein localization to membraneGO:0072657190.016
reproductive structure developmentGO:0048608740.016
enzyme linked receptor protein signaling pathwayGO:00071671790.016
purine ribonucleotide metabolic processGO:00091501450.016
regulation of imaginal disc growthGO:0045570260.016
tissue morphogenesisGO:00487292970.016
establishment of organelle localizationGO:00516561220.016
cell junction assemblyGO:0034329420.015
organic cyclic compound catabolic processGO:19013611680.015
hindgut developmentGO:0061525580.015
cytoplasmic transportGO:00164821300.015
regulation of protein localizationGO:0032880760.015
ribose phosphate biosynthetic processGO:0046390280.015
positive regulation of protein metabolic processGO:00512471280.015
regulation of hemocyte proliferationGO:0035206370.015
actomyosin structure organizationGO:0031032560.015
hindgut morphogenesisGO:0007442580.015
immune system processGO:00023763470.015
protein polymerizationGO:0051258420.015
nucleobase containing compound catabolic processGO:00346551650.014
neurological system processGO:00508773580.014
positive regulation of protein complex assemblyGO:0031334220.014
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.014
purine nucleotide catabolic processGO:00061951090.014
regulation of cellular amine metabolic processGO:003323830.014
regulation of locomotionGO:0040012420.014
heterotypic cell cell adhesionGO:003411310.014
inorganic ion transmembrane transportGO:0098660730.014
cellular component disassemblyGO:0022411460.014
purine nucleotide biosynthetic processGO:0006164290.014
modification dependent protein catabolic processGO:0019941780.014
mitotic nuclear divisionGO:00070672130.014
muscle cell differentiationGO:00426921030.014
response to other organismGO:00517072930.014
positive regulation of organelle organizationGO:0010638650.013
regulation of phosphatase activityGO:001092130.013
macromolecular complex assemblyGO:00650032560.013
negative regulation of cell communicationGO:00106482230.013
nuclear divisionGO:00002803320.013
cell adhesionGO:00071551360.013
purine nucleoside monophosphate metabolic processGO:0009126500.013
positive regulation of catalytic activityGO:00430851180.013
ribonucleoside catabolic processGO:00424541120.013
regulation of protein kinase activityGO:0045859510.013
bmp signaling pathwayGO:0030509270.013
peptidyl amino acid modificationGO:00181931050.013
chromosome localizationGO:0050000200.013
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.013
golgi organizationGO:0007030660.013
cellular macromolecule catabolic processGO:00442651360.013
larval developmentGO:00021641040.013
regulation of microtubule cytoskeleton organizationGO:0070507410.013
establishment of vesicle localizationGO:0051650510.013
regulation of catabolic processGO:00098941700.013
cytosolic calcium ion homeostasisGO:0051480110.013
negative regulation of transcription dna templatedGO:00458922370.013
gland developmentGO:00487321910.013
microtubule depolymerizationGO:0007019250.013
synaptic vesicle transportGO:0048489500.012
chemical homeostasisGO:0048878920.012
ectodermal placode morphogenesisGO:007169740.012
regulation of cell morphogenesisGO:00226041630.012
skin developmentGO:0043588650.012
neuroblast proliferationGO:0007405740.012
regulation of ion transportGO:0043269390.012
Human
triglyceride homeostasisGO:0070328180.012
cellular amide metabolic processGO:0043603800.012
actin filament polymerizationGO:0030041270.012
spermatid developmentGO:0007286980.012
positive regulation of calcium ion transportGO:005192840.012
purine nucleoside biosynthetic processGO:004245130.012
positive regulation of apoptotic processGO:0043065470.012
determination of left right symmetryGO:000736890.012
positive regulation of axon guidanceGO:190266910.012
anterior posterior pattern specification imaginal discGO:0007448160.012
oocyte developmentGO:00485991240.011
protein acylationGO:0043543420.011
lipid localizationGO:0010876540.011
nucleoside monophosphate metabolic processGO:0009123520.011
regulation of protein polymerizationGO:0032271280.011
purine ribonucleoside monophosphate metabolic processGO:0009167500.011
tissue homeostasisGO:0001894360.011
regulation of protein transportGO:0051223570.011
negative regulation of rna biosynthetic processGO:19026792400.011
phosphorylationGO:00163102940.011
Zebrafish
muscle adaptationGO:004350010.011
response to bacteriumGO:00096171980.011
dendrite guidanceGO:0070983210.011
negative regulation of immune responseGO:0050777390.011
negative regulation of signalingGO:00230572190.011
memoryGO:0007613940.011
cellular response to biotic stimulusGO:007121640.011
neurotransmitter secretionGO:0007269350.011
establishment of protein localization to membraneGO:0090150110.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.011
regulation of actin cytoskeleton organizationGO:0032956420.011
connective tissue developmentGO:006144830.011
ribonucleotide catabolic processGO:00092611090.011
protein modification processGO:00362114380.010
developmental maturationGO:00217001720.010
purine ribonucleotide catabolic processGO:00091541090.010
response to growth factorGO:0070848310.010
acylglycerol homeostasisGO:0055090190.010
positive regulation of cell growthGO:0030307190.010
Human
wing disc pattern formationGO:0035222660.010
cellular response to endogenous stimulusGO:0071495800.010
jak stat cascadeGO:0007259490.010
regulation of purine nucleotide metabolic processGO:1900542620.010
regulation of microtubule polymerization or depolymerizationGO:0031110270.010
synaptic vesicle exocytosisGO:0016079160.010
purine containing compound metabolic processGO:00725211550.010
regulation of glutamate receptor signaling pathwayGO:190044910.010
stem cell proliferationGO:0072089880.010

Acsl disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.399
nervous system diseaseDOID:86300.032
central nervous system diseaseDOID:33100.025
neurodegenerative diseaseDOID:128900.016
disease of metabolismDOID:001466700.016
cardiovascular system diseaseDOID:128700.014
intellectual disabilityDOID:105900.014
Human
disease of mental healthDOID:15000.014
Human
non syndromic intellectual disabilityDOID:005088900.014
Human
developmental disorder of mental healthDOID:006003700.014
Human
specific developmental disorderDOID:006003800.014
Human