Drosophila melanogaster

99 known processes

drosha (Dmel_CG8730)

CG8730 gene product from transcript CG8730-RA

(Aliases: Drosha,Dmel\CG8730,CG8730)

drosha biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
oocyte fate determinationGO:0030716270.941
production of mirnas involved in gene silencing by mirnaGO:0035196100.913
dsrna fragmentationGO:0031050150.809
production of small rna involved in gene silencing by rnaGO:0070918150.781
dendrite developmentGO:00163582040.677
germarium derived oocyte differentiationGO:0030706290.635
dendrite morphogenesisGO:00488131990.635
posttranscriptional gene silencingGO:0016441460.632
oocyte differentiationGO:00099941450.543
posttranscriptional gene silencing by rnaGO:0035194450.522
nucleosome positioningGO:001658430.521
chemosensory behaviorGO:00076351060.466
protein modification processGO:00362114380.403
regulation of protein metabolic processGO:00512462560.377
gene silencing by mirnaGO:0035195220.368
regulation of organelle organizationGO:00330431960.364
positive regulation of cellular component organizationGO:00511301560.359
regulation of cell cycleGO:00517262910.342
regulation of cellular amino acid metabolic processGO:000652100.305
positive regulation of gene expressionGO:00106282900.300
organelle fissionGO:00482853400.296
positive regulation of rna metabolic processGO:00512542710.290
rna processingGO:00063961470.286
germarium derived egg chamber formationGO:00072931010.265
positive regulation of rna biosynthetic processGO:19026802660.258
organelle assemblyGO:00709251980.252
epidermal cell differentiationGO:0009913510.245
peptidyl lysine modificationGO:0018205570.241
female germ line cyst formationGO:0048135420.234
negative regulation of biosynthetic processGO:00098902770.231
posttranscriptional regulation of gene expressionGO:00106081450.230
cellular response to dsrnaGO:0071359150.212
axon developmentGO:00615642970.207
positive regulation of transcription dna templatedGO:00458932660.199
regulation of gene expression epigeneticGO:00400291280.194
negative regulation of macromolecule biosynthetic processGO:00105582700.188
response to nitrogen compoundGO:1901698900.184
positive regulation of nucleic acid templated transcriptionGO:19035082660.183
germarium derived oocyte fate determinationGO:0007294260.183
macromolecular complex assemblyGO:00650032560.179
dna metabolic processGO:00062592270.159
response to dsrnaGO:0043331150.152
organonitrogen compound metabolic processGO:19015643180.142
dna repairGO:0006281540.141
ubiquitin dependent protein catabolic processGO:0006511780.136
stem cell proliferationGO:0072089880.135
positive regulation of cellular biosynthetic processGO:00313283160.135
regulation of neuron projection developmentGO:0010975690.133
embryo development ending in birth or egg hatchingGO:00097921520.132
Worm
chromosome segregationGO:00070591570.131
negative regulation of rna metabolic processGO:00512532510.125
gene silencing by rnaGO:0031047570.125
stem cell maintenanceGO:0019827670.124
mitochondrion organizationGO:0007005650.123
regulation of cellular ketone metabolic processGO:001056530.115
production of sirna involved in rna interferenceGO:0030422110.111
reproductive system developmentGO:0061458740.105
regulation of mitotic sister chromatid segregationGO:0033047280.104
cellular macromolecular complex assemblyGO:00346221530.101
cellular amino acid metabolic processGO:0006520610.099
cellular amine metabolic processGO:0044106120.098
regulation of neuron differentiationGO:00456641030.098
regulation of cellular protein metabolic processGO:00322682430.098
oocyte developmentGO:00485991240.097
response to organic cyclic compoundGO:0014070890.094
genitalia developmentGO:0048806260.093
amine metabolic processGO:0009308120.091
cellular response to chemical stimulusGO:00708871990.091
ribonucleoside monophosphate catabolic processGO:0009158390.091
growthGO:00400073590.090
negative regulation of cell differentiationGO:00455961430.086
larval developmentGO:00021641040.085
cellular macromolecule catabolic processGO:00442651360.083
single organism catabolic processGO:00447122280.082
negative regulation of cell cycle processGO:00109481090.081
mitotic g2 m transition checkpointGO:0044818700.080
positive regulation of organelle organizationGO:0010638650.078
germarium derived female germ line cyst formationGO:0030727420.078
mitotic cell cycle phase transitionGO:00447721380.077
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.075
germ line cyst formationGO:0048134440.075
mrna processingGO:00063971040.074
metaphase anaphase transition of cell cycleGO:0044784280.070
transcription from rna polymerase ii promoterGO:00063663680.069
cell cycle checkpointGO:0000075950.069
ribonucleoprotein complex assemblyGO:0022618230.068
regulation of multicellular organismal developmentGO:20000264140.067
regulation of cellular amine metabolic processGO:003323830.067
developmental growthGO:00485892800.064
chromosome organizationGO:00512763600.063
epithelial cell differentiationGO:00308553220.062
regulation of dendrite developmentGO:0050773370.061
stem cell developmentGO:0048864790.060
negative regulation of gene expressionGO:00106293870.059
modification dependent macromolecule catabolic processGO:0043632790.059
cellular protein modification processGO:00064644380.058
positive regulation of nucleobase containing compound metabolic processGO:00459353320.058
epithelial cell migrationGO:00106311480.058
head developmentGO:00603221350.057
ncrna metabolic processGO:0034660430.057
imaginal disc growthGO:0007446370.057
regulation of proteasomal ubiquitin dependent protein catabolic processGO:0032434370.056
negative regulation of nucleic acid templated transcriptionGO:19035072400.056
mitotic dna integrity checkpointGO:0044774750.056
proteolysisGO:00065081920.054
regulation of cell developmentGO:00602842150.054
locomotory behaviorGO:00076261760.054
positive regulation of developmental growthGO:0048639620.053
segmentationGO:00352822070.053
positive regulation of developmental processGO:00510941430.053
reproductive structure developmentGO:0048608740.053
neuron projection guidanceGO:00974852410.052
sex differentiationGO:0007548810.052
epidermis developmentGO:0008544650.052
regulation of cell cycle processGO:00105641810.051
regulation of chromosome organizationGO:0033044640.051
oocyte constructionGO:00073081120.050
negative regulation of intracellular signal transductionGO:1902532570.050
organic acid metabolic processGO:00060821030.048
regulation of response to stressGO:00801342000.048
branching morphogenesis of an epithelial tubeGO:0048754450.047
cell divisionGO:00513012480.047
Worm
multicellular organism growthGO:0035264460.047
nuclear divisionGO:00002803320.047
positive regulation of biosynthetic processGO:00098913160.046
cellular response to organic substanceGO:00713101320.046
axonogenesisGO:00074092900.046
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.046
endocytosisGO:00068973100.045
negative regulation of developmental processGO:00510932010.045
positive regulation of nitrogen compound metabolic processGO:00511733540.044
cell type specific apoptotic processGO:0097285380.044
sister chromatid segregationGO:0000819920.044
rna catabolic processGO:0006401370.042
regulation of phosphate metabolic processGO:00192202100.041
negative regulation of protein metabolic processGO:0051248850.040
programmed cell deathGO:00125012570.040
proteasome mediated ubiquitin dependent protein catabolic processGO:0043161540.040
negative regulation of nitrogen compound metabolic processGO:00511722650.040
purine ribonucleoside monophosphate catabolic processGO:0009169380.040
oxoacid metabolic processGO:00434361030.040
regulation of wnt signaling pathwayGO:0030111680.039
cell motilityGO:00488702510.038
learning or memoryGO:00076111410.038
mrna metabolic processGO:00160711240.038
blastoderm segmentationGO:00073501590.037
negative regulation of phosphorylationGO:0042326350.037
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.036
response to abiotic stimulusGO:00096283410.036
cellular component assembly involved in morphogenesisGO:00109271510.035
nucleosome organizationGO:0034728590.035
positive regulation of multicellular organism growthGO:0040018210.035
gene silencingGO:00164581380.035
regulation of phosphorus metabolic processGO:00511742100.034
skin developmentGO:0043588650.034
regulation of epidermal cell differentiationGO:004560430.034
muscle structure developmentGO:00610612240.034
dna integrity checkpointGO:0031570810.033
cellular catabolic processGO:00442483720.033
targeting of mrna for destruction involved in rna interferenceGO:003042340.033
cellular ketone metabolic processGO:0042180240.033
regulation of epithelial cell differentiationGO:003085640.033
outflow tract morphogenesisGO:000315140.033
positive regulation of response to stimulusGO:00485843230.032
locomotor rhythmGO:0045475560.032
regulation of cell cycle phase transitionGO:19019871300.032
positive regulation of macromolecule biosynthetic processGO:00105572830.032
negative regulation of cellular metabolic processGO:00313243820.031
mitotic cell cycle checkpointGO:0007093880.030
rna phosphodiester bond hydrolysisGO:0090501170.030
Human Worm
single organism behaviorGO:00447083910.030
organic substance catabolic processGO:19015753080.030
negative regulation of cellular biosynthetic processGO:00313272770.030
columnar cuboidal epithelial cell differentiationGO:00020652560.030
mitotic sister chromatid segregationGO:0000070870.029
central nervous system developmentGO:00074172010.029
negative regulation of mitotic cell cycleGO:00459301090.029
covalent chromatin modificationGO:00165691060.029
chromatin organizationGO:00063252070.029
mushroom body developmentGO:0016319700.029
regulation of mrna metabolic processGO:1903311720.029
regulation of developmental growthGO:00486381740.029
columnar cuboidal epithelial cell developmentGO:00020662490.029
small molecule metabolic processGO:00442813050.029
telencephalon developmentGO:002153720.028
karyosome formationGO:0030717220.028
positive regulation of transportGO:0051050920.027
positive regulation of macromolecule metabolic processGO:00106044050.027
rna interferenceGO:0016246270.027
body morphogenesisGO:001017120.026
regulation of phosphorylationGO:00423251470.026
dna conformation changeGO:00711031050.026
oocyte axis specificationGO:00073091080.026
response to organic substanceGO:00100332840.026
heterocycle catabolic processGO:00467001660.026
cell fate specificationGO:0001708710.025
negative regulation of phosphorus metabolic processGO:0010563450.025
positive regulation of proteolysis involved in cellular protein catabolic processGO:1903052240.025
taxisGO:00423303040.025
regulation of multi organism processGO:00439001310.024
regulation of stem cell proliferationGO:0072091400.024
histone h3 k9 acetylationGO:004397030.024
muscle organ developmentGO:00075171270.024
enzyme linked receptor protein signaling pathwayGO:00071671790.024
carboxylic acid metabolic processGO:0019752920.024
neurological system processGO:00508773580.024
dna damage checkpointGO:0000077780.023
mitotic nuclear divisionGO:00070672130.023
eye developmentGO:00016543230.023
protein complex biogenesisGO:00702712010.023
defense response to other organismGO:00985422250.023
Human
ribonucleoprotein complex subunit organizationGO:0071826280.023
cellular response to organic cyclic compoundGO:0071407320.023
regulation of multicellular organism growthGO:0040014400.022
neuroblast proliferationGO:0007405740.022
embryonic pattern specificationGO:00098801740.021
regulation of metaphase anaphase transition of cell cycleGO:1902099260.021
chromosome separationGO:0051304420.021
regulation of catabolic processGO:00098941700.020
secretion by cellGO:00329401010.020
positive regulation of cellular amino acid metabolic processGO:004576400.020
negative regulation of multicellular organismal processGO:00512411420.020
development of primary sexual characteristicsGO:0045137500.020
anaphase promoting complex dependent proteasomal ubiquitin dependent protein catabolic processGO:0031145300.020
positive regulation of cellular amine metabolic processGO:003324000.020
positive regulation of cell differentiationGO:0045597640.020
macromolecule catabolic processGO:00090571610.020
positive regulation of protein metabolic processGO:00512471280.019
regulation of neurogenesisGO:00507671580.019
maternal specification of dorsal ventral axis oocyte germ line encodedGO:000731140.019
regulation of cell deathGO:00109411730.019
olfactory behaviorGO:0042048970.019
hematopoietic progenitor cell differentiationGO:000224410.019
positive regulation of cellular protein metabolic processGO:00322701180.019
positive regulation of signalingGO:00230562430.018
ncrna processingGO:0034470300.018
positive regulation of cell developmentGO:0010720610.018
peptidyl amino acid modificationGO:00181931050.018
response to oxidative stressGO:0006979860.017
positive regulation of multicellular organismal processGO:00512401430.017
autophagyGO:00069141080.017
organ growthGO:0035265560.017
regionalizationGO:00030024160.017
spinal cord developmentGO:002151010.017
brain developmentGO:00074201200.017
mitotic dna damage checkpointGO:0044773740.017
regulation of protein complex assemblyGO:0043254420.017
protein complex assemblyGO:00064612000.017
spindle assemblyGO:0051225800.017
negative regulation of g1 s transition of mitotic cell cycleGO:2000134130.017
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.017
regulation of cell differentiationGO:00455953020.017
nuclear transcribed mrna catabolic processGO:0000956240.017
purine ribonucleoside triphosphate metabolic processGO:00092051190.016
purine nucleoside metabolic processGO:00422781270.016
cellular response to nitrogen compoundGO:1901699510.016
mitotic g2 dna damage checkpointGO:0007095690.016
localization of cellGO:00516742570.016
negative regulation of response to stimulusGO:00485852580.016
protein transportGO:00150311550.016
catabolic processGO:00090564090.016
cellular nitrogen compound catabolic processGO:00442701650.016
protein acylationGO:0043543420.016
regulation of small gtpase mediated signal transductionGO:0051056930.015
cell fate determinationGO:0001709910.015
gonad developmentGO:0008406500.015
mitotic sister chromatid separationGO:0051306300.015
sensory organ morphogenesisGO:00905962600.015
regulation of growthGO:00400082330.015
dorsal ventral pattern formationGO:00099531330.015
regulation of cell proliferationGO:00421271630.015
purine nucleoside catabolic processGO:00061521120.015
proteolysis involved in cellular protein catabolic processGO:0051603830.015
positive regulation of neurogenesisGO:0050769410.015
histone h2a ubiquitinationGO:003352220.015
regulation of gene silencing by mirnaGO:006096480.014
ribonucleotide catabolic processGO:00092611090.014
negative regulation of nucleobase containing compound metabolic processGO:00459342610.014
translationGO:0006412690.014
response to hypoxiaGO:0001666530.014
negative regulation of cell cycle phase transitionGO:19019881030.014
modification dependent protein catabolic processGO:0019941780.014
multi organism behaviorGO:00517051750.014
meiotic nuclear divisionGO:00071261510.014
nucleoside monophosphate catabolic processGO:0009125390.014
dna dependent dna replicationGO:0006261170.013
cell cycle phase transitionGO:00447701400.013
cellular response to external stimulusGO:0071496660.013
establishment of protein localizationGO:00451841630.013
organic cyclic compound catabolic processGO:19013611680.013
mrna catabolic processGO:0006402330.013
nucleotide catabolic processGO:00091661090.013
regulation of g1 s transition of mitotic cell cycleGO:2000045230.013
atp dependent chromatin remodelingGO:0043044220.013
nucleosome mobilizationGO:004276690.013
cognitionGO:00508901410.013
regulation of chromatin modificationGO:1903308280.013
negative regulation of cell cycle g1 s phase transitionGO:1902807130.013
regulation of nervous system developmentGO:00519602480.013
positive regulation of growthGO:0045927750.013
phagocytosisGO:00069092150.013
defense responseGO:00069523000.013
Human
regulation of histone modificationGO:0031056200.013
chromatin modificationGO:00165681470.013
ribosomal large subunit biogenesisGO:004227310.012
protein dna complex subunit organizationGO:0071824860.012
actin polymerization or depolymerizationGO:0008154310.012
histone modificationGO:00165701060.012
regulation of mitotic cell cycleGO:00073461900.012
regulation of proteasomal protein catabolic processGO:0061136390.012
regulation of programmed cell deathGO:00430671520.012
olfactory learningGO:0008355560.012
cell growthGO:00160491080.012
nucleobase containing compound transportGO:0015931560.012
eye morphogenesisGO:00485922600.012
dna alkylationGO:000630540.012
digestive tract developmentGO:00485651490.012
rna 3 end processingGO:0031123450.012
histone ubiquitinationGO:001657440.012
dephosphorylationGO:0016311510.011
compound eye developmentGO:00487493070.011
tube fusionGO:0035146170.011
organophosphate catabolic processGO:00464341120.011
regulation of reproductive processGO:2000241540.011
apoptotic processGO:00069151590.011
negative regulation of nervous system developmentGO:0051961920.011
regulation of apoptotic processGO:00429811300.011
organic substance transportGO:00717022570.011
response to oxygen containing compoundGO:19017002000.011
developmental maturationGO:00217001720.011
single organism biosynthetic processGO:00447112060.011
deathGO:00162652840.011
ameboidal type cell migrationGO:00016671510.011
negative regulation of cell deathGO:0060548810.011
negative regulation of organelle organizationGO:0010639560.011
ribonucleoside catabolic processGO:00424541120.011
regulation of sister chromatid segregationGO:0033045280.011
regulation of gene silencingGO:0060968630.011
positive regulation of intracellular signal transductionGO:19025331160.011
mapk cascadeGO:00001651070.011
amino acid activationGO:004303830.011
dendrite guidanceGO:0070983210.010
eye photoreceptor cell differentiationGO:00017541450.010
regulation of transcription by chromatin organizationGO:003440130.010
regulation of mrna processingGO:0050684710.010
regulation of localizationGO:00328792750.010
phosphorylationGO:00163102940.010
gliogenesisGO:0042063800.010
histone exchangeGO:0043486210.010
cellular protein localizationGO:00346131600.010
purine nucleoside monophosphate metabolic processGO:0009126500.010
digestive system developmentGO:00551231490.010

drosha disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of cellular proliferationDOID:1456600.066
cancerDOID:16200.027
disease of anatomical entityDOID:700.026
organ system cancerDOID:005068600.023