IMP: Integrative Multi-species Prediction

Drosophila melanogaster

47 known processes

qm (Dmel_CG8593)

quemao

(Aliases: GGPPS,GGPPS/qm,CG8593,Dmel\CG8593,bro2)

FLYBASE: FBgn0019662
Entrez: 38816
UniProtKB: M9PEL3
UniProtKB: Q9VS54

Process Predictions
Disease Predictions

qm biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
blastoderm segmentation	GO:0007350	159	0.741
molting cycle chitin based cuticle	GO:0007591	56	0.714
appendage development	GO:0048736	401	0.681
developmental maturation	GO:0021700	172	0.637
embryonic development via the syncytial blastoderm	GO:0001700	148	0.614
regulation of organ morphogenesis	GO:2000027	78	0.556
negative regulation of biosynthetic process	GO:0009890	277	0.532
regionalization	GO:0003002	416	0.480
oocyte differentiation	GO:0009994	145	0.452
tube development	GO:0035295	244	0.387
oocyte development	GO:0048599	124	0.350
tissue morphogenesis	GO:0048729	297	0.347
neuron recognition	GO:0008038	101	0.336
axon development	GO:0061564	297	0.313
pole plasm oskar mrna localization	GO:0045451	46	0.299
embryonic pattern specification	GO:0009880	174	0.279
oocyte construction	GO:0007308	112	0.279
oocyte anterior posterior axis specification	GO:0007314	72	0.274
germ cell migration	GO:0008354	43	0.272
rna localization	GO:0006403	115	0.272
oocyte axis specification	GO:0007309	108	0.266
pole plasm rna localization	GO:0007316	52	0.246
segmentation	GO:0035282	207	0.239
axonogenesis	GO:0007409	290	0.239
cytoplasm organization	GO:0007028	64	0.228
reproductive system development	GO:0061458	74	0.226
mating	GO:0007618	120	0.226
pole plasm mrna localization	GO:0019094	49	0.221
pole plasm assembly	GO:0007315	61	0.221
neuron projection guidance	GO:0097485	241	0.214
dendrite morphogenesis	GO:0048813	199	0.210
anterior posterior axis specification embryo	GO:0008595	103	0.196
positive regulation of multicellular organismal process	GO:0051240	143	0.194
growth	GO:0040007	359	0.189
central nervous system development	GO:0007417	201	0.184
mating behavior	GO:0007617	106	0.178
dendrite development	GO:0016358	204	0.175
cardiovascular system development	GO:0072358	82	0.175
organelle fission	GO:0048285	340	0.169
embryonic heart tube development	GO:0035050	22	0.165
cell maturation	GO:0048469	144	0.164
heart development	GO:0007507	82	0.159
gastrulation	GO:0007369	70	0.158
molting cycle	GO:0042303	56	0.157
reproductive structure development	GO:0048608	74	0.156
maternal determination of anterior posterior axis embryo	GO:0008358	74	0.156
epithelial cell differentiation	GO:0030855	322	0.154
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.133
sex differentiation	GO:0007548	81	0.128
muscle cell differentiation	GO:0042692	103	0.118
multi multicellular organism process	GO:0044706	123	0.115
circulatory system development	GO:0072359	82	0.112
positive regulation of gene expression	GO:0010628	290	0.111
body morphogenesis	GO:0010171	2	0.110
multi organism reproductive behavior	GO:0044705	121	0.110
imaginal disc derived appendage development	GO:0048737	399	0.108
embryo development ending in birth or egg hatching	GO:0009792	152	0.108
intracellular mrna localization involved in anterior posterior axis specification	GO:0060811	53	0.108
muscle organ development	GO:0007517	127	0.107
digestive tract development	GO:0048565	149	0.106
renal tubule development	GO:0061326	64	0.106
tripartite regional subdivision	GO:0007351	103	0.103
lateral inhibition	GO:0046331	206	0.103
neural precursor cell proliferation	GO:0061351	75	0.102
intracellular mrna localization involved in pattern specification process	GO:0060810	56	0.101
axon guidance	GO:0007411	233	0.100
reproductive behavior	GO:0019098	122	0.096
regulation of localization	GO:0032879	275	0.096
nuclear division	GO:0000280	332	0.095
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.095
regulation of cell development	GO:0060284	215	0.094
positive regulation of nervous system development	GO:0051962	69	0.093
morphogenesis of a polarized epithelium	GO:0001738	93	0.086
lipid metabolic process	GO:0006629	121	0.086
appendage morphogenesis	GO:0035107	397	0.085
embryonic axis specification	GO:0000578	107	0.084
muscle structure development	GO:0061061	224	0.084
axon midline choice point recognition	GO:0016199	26	0.083
gland morphogenesis	GO:0022612	145	0.083
locomotory behavior	GO:0007626	176	0.082
regulation of cuticle pigmentation	GO:0048079	16	0.082
embryonic morphogenesis	GO:0048598	206	0.081
mesodermal cell fate commitment	GO:0001710	7	0.080
chemosensory behavior	GO:0007635	106	0.079
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.079
regulation of dendrite morphogenesis	GO:0048814	28	0.077
gene silencing	GO:0016458	138	0.076
imaginal disc derived wing morphogenesis	GO:0007476	337	0.076
gland development	GO:0048732	191	0.076
regulation of dendrite development	GO:0050773	37	0.074
oocyte microtubule cytoskeleton organization	GO:0016325	35	0.073
male courtship behavior	GO:0008049	63	0.072
histolysis	GO:0007559	102	0.072
regulation of neuron differentiation	GO:0045664	103	0.071
negative regulation of cellular biosynthetic process	GO:0031327	277	0.070
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.070
pronuclear migration	GO:0035046	4	0.069
courtship behavior	GO:0007619	68	0.069
chemotaxis	GO:0006935	249	0.066
forebrain development	GO:0030900	2	0.064
positive regulation of phosphate metabolic process	GO:0045937	139	0.064
neurological system process	GO:0050877	358	0.064
delamination	GO:0060232	8	0.064
regulation of cell cycle	GO:0051726	291	0.063
vesicle mediated transport	GO:0016192	381	0.063
meiotic nuclear division	GO:0007126	151	0.061
telencephalon development	GO:0021537	2	0.061
regulation of mitotic cell cycle	GO:0007346	190	0.061
developmental growth	GO:0048589	280	0.060
muscle cell development	GO:0055001	50	0.059
photoreceptor cell differentiation	GO:0046530	170	0.058
cell proliferation	GO:0008283	299	0.056
single organism behavior	GO:0044708	391	0.054
male courtship behavior veined wing vibration	GO:0016545	21	0.054
chorion containing eggshell formation	GO:0007304	105	0.054
striated muscle cell differentiation	GO:0051146	90	0.053
male courtship behavior veined wing extension	GO:0048065	22	0.053
post embryonic appendage morphogenesis	GO:0035120	385	0.053
regulation of anatomical structure morphogenesis	GO:0022603	242	0.052
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.052
nuclear migration	GO:0007097	20	0.052
axis specification	GO:0009798	167	0.052
morphogenesis of an epithelium	GO:0002009	276	0.051
sensory organ morphogenesis	GO:0090596	260	0.050
eye photoreceptor cell differentiation	GO:0001754	145	0.050
cell recognition	GO:0008037	102	0.050
positive regulation of cellular biosynthetic process	GO:0031328	316	0.047
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.047
negative regulation of gene expression	GO:0010629	387	0.047
regulation of neurogenesis	GO:0050767	158	0.047
striated muscle cell development	GO:0055002	50	0.047
photoreceptor cell development	GO:0042461	96	0.046
meiotic cell cycle	GO:0051321	171	0.046
positive regulation of nucleic acid templated transcription	GO:1903508	266	0.045
cuticle development	GO:0042335	86	0.045
axon choice point recognition	GO:0016198	26	0.044
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.044
sensory perception	GO:0007600	196	0.044
developmental programmed cell death	GO:0010623	138	0.043
oocyte microtubule cytoskeleton polarization	GO:0008103	22	0.043
mitotic cell cycle phase transition	GO:0044772	138	0.043
negative regulation of signal transduction	GO:0009968	206	0.043
regulation of mapk cascade	GO:0043408	92	0.042
embryonic hindgut morphogenesis	GO:0048619	48	0.041
signal transduction by phosphorylation	GO:0023014	107	0.041
positive regulation of cell development	GO:0010720	61	0.041
positive regulation of cell cycle	GO:0045787	43	0.041
positive regulation of cell differentiation	GO:0045597	64	0.040
malpighian tubule development	GO:0072002	64	0.039
cellular component assembly involved in morphogenesis	GO:0010927	151	0.039
imaginal disc derived leg morphogenesis	GO:0007480	80	0.039
anterior posterior pattern specification	GO:0009952	136	0.039
regulation of chromosome organization	GO:0033044	64	0.039
organic hydroxy compound biosynthetic process	GO:1901617	21	0.039
compound eye morphogenesis	GO:0001745	249	0.038
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.038
cell fate determination	GO:0001709	91	0.038
intracellular mrna localization	GO:0008298	66	0.037
rna processing	GO:0006396	147	0.037
regulation of multicellular organismal development	GO:2000026	414	0.037
associative learning	GO:0008306	65	0.036
regulation of protein metabolic process	GO:0051246	256	0.036
wing disc morphogenesis	GO:0007472	344	0.035
regulation of translation	GO:0006417	56	0.035
salivary gland morphogenesis	GO:0007435	145	0.035
fertilization	GO:0009566	26	0.035
synapse organization	GO:0050808	196	0.033
multicellular organismal reproductive behavior	GO:0033057	110	0.033
transcription from rna polymerase ii promoter	GO:0006366	368	0.033
regulation of organelle organization	GO:0033043	196	0.033
epithelial tube morphogenesis	GO:0060562	88	0.033
compound eye photoreceptor cell differentiation	GO:0001751	140	0.033
eye photoreceptor cell development	GO:0042462	81	0.033
gonad development	GO:0008406	50	0.033
negative regulation of cellular metabolic process	GO:0031324	382	0.033
death	GO:0016265	284	0.032
establishment of nucleus localization	GO:0040023	26	0.032
positive regulation of signal transduction	GO:0009967	223	0.032
organelle assembly	GO:0070925	198	0.032
cellular amino acid metabolic process	GO:0006520	61	0.032
positive regulation of neuron differentiation	GO:0045666	26	0.032
regulation of cell differentiation	GO:0045595	302	0.032
positive regulation of neurogenesis	GO:0050769	41	0.032
negative regulation of rna metabolic process	GO:0051253	251	0.031
organonitrogen compound metabolic process	GO:1901564	318	0.031
renal tubule morphogenesis	GO:0061333	44	0.031
positive regulation of macromolecule metabolic process	GO:0010604	405	0.031
embryonic organ development	GO:0048568	50	0.030
negative regulation of rna biosynthetic process	GO:1902679	240	0.030
developmental growth involved in morphogenesis	GO:0060560	65	0.030
leg disc development	GO:0035218	92	0.030
mrna processing	GO:0006397	104	0.030
protein localization	GO:0008104	284	0.030
compound eye development	GO:0048749	307	0.029
mrna metabolic process	GO:0016071	124	0.029
maintenance of location	GO:0051235	73	0.029
muscle tissue morphogenesis	GO:0060415	2	0.029
leg disc morphogenesis	GO:0007478	80	0.029
nucleus localization	GO:0051647	34	0.029
positive regulation of transcription dna templated	GO:0045893	266	0.029
salivary gland development	GO:0007431	162	0.028
development of primary sexual characteristics	GO:0045137	50	0.028
molting cycle process	GO:0022404	29	0.028
translation	GO:0006412	69	0.027
cell migration	GO:0016477	238	0.027
mesoderm formation	GO:0001707	21	0.027
establishment of organelle localization	GO:0051656	122	0.027
microtubule based movement	GO:0007018	51	0.027
localization of cell	GO:0051674	257	0.027
regulation of synapse structure and activity	GO:0050803	128	0.027
compound eye photoreceptor development	GO:0042051	78	0.027
sensory perception of mechanical stimulus	GO:0050954	72	0.026
olfactory behavior	GO:0042048	97	0.026
oocyte nucleus localization involved in oocyte dorsal ventral axis specification	GO:0051663	12	0.026
limb development	GO:0060173	1	0.025
immune system process	GO:0002376	347	0.025
neuron fate commitment	GO:0048663	50	0.025
phagocytosis	GO:0006909	215	0.025
single fertilization	GO:0007338	24	0.024
positive regulation of phosphorus metabolic process	GO:0010562	139	0.024
digestive tract morphogenesis	GO:0048546	127	0.024
organic hydroxy compound metabolic process	GO:1901615	83	0.024
salivary gland histolysis	GO:0035070	88	0.024
positive regulation of response to stimulus	GO:0048584	323	0.024
positive regulation of catabolic process	GO:0009896	105	0.024
anterior posterior axis specification	GO:0009948	109	0.024
actin filament organization	GO:0007015	126	0.023
single organism cellular localization	GO:1902580	180	0.023
regulation of mrna metabolic process	GO:1903311	72	0.023
kidney epithelium development	GO:0072073	3	0.023
brain development	GO:0007420	120	0.023
axonal fasciculation	GO:0007413	12	0.022
positive regulation of rna biosynthetic process	GO:1902680	266	0.022
cellularization	GO:0007349	90	0.022
multi organism behavior	GO:0051705	175	0.022
cell death	GO:0008219	279	0.022
mitotic nuclear division	GO:0007067	213	0.022
establishment of localization in cell	GO:0051649	402	0.021
formation of primary germ layer	GO:0001704	24	0.021
muscle organ morphogenesis	GO:0048644	7	0.020
muscle fiber development	GO:0048747	12	0.020
regulation of growth	GO:0040008	233	0.020
endocytosis	GO:0006897	310	0.020
cellular macromolecule localization	GO:0070727	220	0.020
actin polymerization or depolymerization	GO:0008154	31	0.020
stem cell proliferation	GO:0072089	88	0.020
tracheal outgrowth open tracheal system	GO:0007426	18	0.020
learning	GO:0007612	75	0.020
genitalia development	GO:0048806	26	0.020
regulation of rna splicing	GO:0043484	69	0.020
malpighian tubule morphogenesis	GO:0007443	44	0.019
regulation of phosphate metabolic process	GO:0019220	210	0.019
positive regulation of rna metabolic process	GO:0051254	271	0.019
positive regulation of biosynthetic process	GO:0009891	316	0.019
negative regulation of signaling	GO:0023057	219	0.019
regulation of cell proliferation	GO:0042127	163	0.019
positive regulation of cell communication	GO:0010647	250	0.019
epithelial cell migration open tracheal system	GO:0007427	32	0.019
head development	GO:0060322	135	0.019
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.018
positive regulation of developmental process	GO:0051094	143	0.018
mesodermal cell differentiation	GO:0048333	7	0.018
peripheral nervous system development	GO:0007422	52	0.018
intracellular signal transduction	GO:0035556	300	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.018
regulation of notch signaling pathway	GO:0008593	100	0.018
regulation of neuron projection development	GO:0010975	69	0.018
cellular ketone metabolic process	GO:0042180	24	0.018
regulation of phosphatase activity	GO:0010921	3	0.018
establishment of tissue polarity	GO:0007164	87	0.018
organic substance transport	GO:0071702	257	0.017
epithelial cell development	GO:0002064	274	0.017
cellular catabolic process	GO:0044248	372	0.017
regulation of dna templated transcription elongation	GO:0032784	17	0.017
tube morphogenesis	GO:0035239	191	0.017
tissue migration	GO:0090130	155	0.017
limb morphogenesis	GO:0035108	1	0.017
axon cargo transport	GO:0008088	29	0.016
response to organic substance	GO:0010033	284	0.016
positive regulation of cell projection organization	GO:0031346	29	0.016
larval heart development	GO:0007508	6	0.016
digestive system development	GO:0055123	149	0.016
photoreceptor cell fate commitment	GO:0046552	41	0.016
instar larval development	GO:0002168	55	0.016
regulation of protein localization	GO:0032880	76	0.016
mesoderm development	GO:0007498	78	0.016
extracellular matrix disassembly	GO:0022617	4	0.016
response to hypoxia	GO:0001666	53	0.016
regulation of meiosis	GO:0040020	3	0.016
small molecule metabolic process	GO:0044281	305	0.016
single organism intracellular transport	GO:1902582	207	0.015
protein modification process	GO:0036211	438	0.015
neuroblast division	GO:0055057	35	0.015
posttranscriptional regulation of gene expression	GO:0010608	145	0.015
chromatin organization	GO:0006325	207	0.015
negative regulation of response to stimulus	GO:0048585	258	0.015
innate immune response	GO:0045087	144	0.015
cell cycle phase transition	GO:0044770	140	0.015
rhabdomere development	GO:0042052	38	0.015
male meiosis	GO:0007140	52	0.015
erk1 and erk2 cascade	GO:0070371	39	0.015
regulation of molecular function	GO:0065009	217	0.015
cranial nerve development	GO:0021545	1	0.015
cell fate commitment involved in pattern specification	GO:0060581	31	0.015
negative regulation of organelle organization	GO:0010639	56	0.015
neuroblast proliferation	GO:0007405	74	0.014
extrinsic apoptotic signaling pathway	GO:0097191	1	0.014
central nervous system neuron differentiation	GO:0021953	8	0.014
compound eye photoreceptor fate commitment	GO:0001752	36	0.014
larval development	GO:0002164	104	0.014
regulation of mrna processing	GO:0050684	71	0.014
oxidation reduction process	GO:0055114	123	0.014
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.014
microtubule based transport	GO:0010970	42	0.014
regulation of cellular catabolic process	GO:0031329	157	0.014
stem cell differentiation	GO:0048863	117	0.013
mapk cascade	GO:0000165	107	0.013
positive regulation of transcription factor import into nucleus	GO:0042993	19	0.013
organic cyclic compound catabolic process	GO:1901361	168	0.013
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.013
ras protein signal transduction	GO:0007265	88	0.013
cellular protein modification process	GO:0006464	438	0.013
rna 3 end processing	GO:0031123	45	0.013
small gtpase mediated signal transduction	GO:0007264	88	0.013
exocrine system development	GO:0035272	162	0.013
regulation of cellular response to stress	GO:0080135	89	0.013
morphogenesis of a branching epithelium	GO:0061138	45	0.013
chromosome organization	GO:0051276	360	0.013
urogenital system development	GO:0001655	72	0.013
cardioblast differentiation	GO:0010002	20	0.013
respiratory system development	GO:0060541	213	0.013
negative regulation of cell cycle	GO:0045786	116	0.013
regulation of cell division	GO:0051302	72	0.013
positive regulation of intracellular signal transduction	GO:1902533	116	0.013
renal system development	GO:0072001	72	0.012
eggshell formation	GO:0030703	105	0.012
eye morphogenesis	GO:0048592	260	0.012
cellular component disassembly	GO:0022411	46	0.012
defense response to other organism	GO:0098542	225	0.012
negative regulation of sequence specific dna binding transcription factor activity	GO:0043433	4	0.012
actin filament polymerization	GO:0030041	27	0.012
negative regulation of cytoskeleton organization	GO:0051494	30	0.012
negative regulation of cell communication	GO:0010648	223	0.012
nucleus organization	GO:0006997	45	0.012
regulation of microtubule depolymerization	GO:0031114	24	0.012
regulation of ras protein signal transduction	GO:0046578	93	0.012
response to alcohol	GO:0097305	95	0.012
hindgut morphogenesis	GO:0007442	58	0.012
carboxylic acid metabolic process	GO:0019752	92	0.012
nitrogen compound transport	GO:0071705	85	0.012
glycosyl compound catabolic process	GO:1901658	112	0.012
actin cytoskeleton organization	GO:0030036	206	0.011
meiotic spindle organization	GO:0000212	36	0.011
regulation of cellular protein metabolic process	GO:0032268	243	0.011
single organism biosynthetic process	GO:0044711	206	0.011
positive regulation of phosphorylation	GO:0042327	87	0.011
hindbrain development	GO:0030902	2	0.011
taxis	GO:0042330	304	0.011
regulation of protein modification process	GO:0031399	112	0.011
regulation of catalytic activity	GO:0050790	185	0.011
cytoskeleton dependent intracellular transport	GO:0030705	44	0.011
salivary gland cell autophagic cell death	GO:0035071	83	0.011
bicoid mrna localization	GO:0045450	8	0.011
amine metabolic process	GO:0009308	12	0.011
establishment of rna localization	GO:0051236	47	0.011
synaptic growth at neuromuscular junction	GO:0051124	119	0.011
regulation of erk1 and erk2 cascade	GO:0070372	39	0.011
notch signaling pathway	GO:0007219	120	0.011
cytoplasmic transport nurse cell to oocyte	GO:0007303	12	0.011
oocyte dorsal ventral axis specification	GO:0007310	34	0.011
ventral furrow formation	GO:0007370	17	0.011
sleep	GO:0030431	49	0.011
regulation of cell cycle phase transition	GO:1901987	130	0.010
border follicle cell migration	GO:0007298	113	0.010
eye development	GO:0001654	323	0.010
positive regulation of cellular component organization	GO:0051130	156	0.010
regulation of protein depolymerization	GO:1901879	27	0.010
positive regulation of signaling	GO:0023056	243	0.010
protein polymerization	GO:0051258	42	0.010
cytokinesis	GO:0000910	90	0.010
regulation of epithelial cell migration open tracheal system	GO:2000274	11	0.010
positive regulation of cellular catabolic process	GO:0031331	95	0.010

qm disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
cardiovascular system disease	DOID:1287	0.033
disease of anatomical entity	DOID:7	0.033
nervous system disease	DOID:863	0.020

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