Drosophila melanogaster

16 known processes

APP-BP1 (Dmel_CG7828)

beta-Amyloid precursor protein binding protein 1

(Aliases: Dmel\CG7828,CG7828,anon-WO0140519.225,APPBP1,dAPP-BP1)

APP-BP1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.170
regulation of cell deathGO:00109411730.139
protein complex biogenesisGO:00702712010.123
homeostatic processGO:00425921990.115
positive regulation of programmed cell deathGO:0043068620.114
epithelial cell differentiationGO:00308553220.114
compound eye morphogenesisGO:00017452490.088
transcription from rna polymerase ii promoterGO:00063663680.087
columnar cuboidal epithelial cell developmentGO:00020662490.087
protein modification by small protein conjugation or removalGO:00706471060.083
oxidation reduction processGO:00551141230.081
positive regulation of cell deathGO:0010942690.076
cellular macromolecular complex assemblyGO:00346221530.076
cell proliferationGO:00082832990.076
regionalizationGO:00030024160.072
rna splicing via transesterification reactions with bulged adenosine as nucleophileGO:0000377730.071
regulation of erbb signaling pathwayGO:1901184420.069
columnar cuboidal epithelial cell differentiationGO:00020652560.068
cell deathGO:00082192790.067
regulation of cell developmentGO:00602842150.067
ovarian follicle cell developmentGO:00307072480.066
positive regulation of macromolecule metabolic processGO:00106044050.066
regulation of apoptotic processGO:00429811300.065
negative regulation of signalingGO:00230572190.061
positive regulation of response to stimulusGO:00485843230.060
vesicle mediated transportGO:00161923810.060
appendage morphogenesisGO:00351073970.060
ribonucleoside triphosphate metabolic processGO:00091991190.057
response to oxidative stressGO:0006979860.055
single organism membrane fusionGO:0044801420.054
regulation of cell cycleGO:00517262910.054
negative regulation of response to stimulusGO:00485852580.053
intracellular transportGO:00469072280.050
programmed cell deathGO:00125012570.049
regulation of cell cycle processGO:00105641810.049
organelle assemblyGO:00709251980.049
epithelial cell developmentGO:00020642740.048
proteolysisGO:00065081920.048
atp metabolic processGO:0046034490.048
regulation of mitotic cell cycleGO:00073461900.047
negative regulation of signal transductionGO:00099682060.047
rna processingGO:00063961470.046
positive regulation of apoptotic signaling pathwayGO:200123540.045
negative regulation of nucleic acid templated transcriptionGO:19035072400.045
rna splicingGO:0008380830.045
protein modification processGO:00362114380.045
eye developmentGO:00016543230.043
membrane fusionGO:0061025420.042
eye morphogenesisGO:00485922600.042
axonogenesisGO:00074092900.042
endocytosisGO:00068973100.042
intrinsic apoptotic signaling pathwayGO:0097193160.041
negative regulation of cell communicationGO:00106482230.041
positive regulation of cell communicationGO:00106472500.040
skin developmentGO:0043588650.040
imaginal disc derived appendage developmentGO:00487373990.038
erbb signaling pathwayGO:0038127580.038
ribonucleoside metabolic processGO:00091191270.038
segmentationGO:00352822070.038
cell divisionGO:00513012480.037
endosomal transportGO:0016197440.037
positive regulation of proteolysisGO:0045862520.037
positive regulation of gene expressionGO:00106282900.036
negative regulation of transcription dna templatedGO:00458922370.036
positive regulation of nucleobase containing compound metabolic processGO:00459353320.036
positive regulation of nitrogen compound metabolic processGO:00511733540.035
regulation of catalytic activityGO:00507901850.035
membrane organizationGO:00610241120.034
purine ribonucleoside metabolic processGO:00461281270.034
positive regulation of endopeptidase activityGO:0010950260.034
appendage developmentGO:00487364010.034
enzyme linked receptor protein signaling pathwayGO:00071671790.034
glycosyl compound metabolic processGO:19016571270.033
regulation of cell differentiationGO:00455953020.033
response to radiationGO:00093141550.032
epidermal growth factor receptor signaling pathwayGO:0007173580.032
regulation of cell cycle phase transitionGO:19019871300.032
regulation of transcription from rna polymerase ii promoterGO:00063573780.031
negative regulation of cell deathGO:0060548810.030
response to external biotic stimulusGO:00432072930.030
defense response to other organismGO:00985422250.030
regulation of wnt signaling pathwayGO:0030111680.030
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.029
morphogenesis of a polarized epitheliumGO:0001738930.029
chromosome segregationGO:00070591570.029
neuron projection guidanceGO:00974852410.028
cell motilityGO:00488702510.028
nucleoside phosphate metabolic processGO:00067531620.028
positive regulation of transcription dna templatedGO:00458932660.027
negative regulation of developmental processGO:00510932010.027
purine ribonucleoside catabolic processGO:00461301120.027
regulation of response to stressGO:00801342000.027
purine ribonucleoside monophosphate metabolic processGO:0009167500.027
tissue morphogenesisGO:00487292970.026
macromolecular complex assemblyGO:00650032560.026
regulation of cellular component sizeGO:0032535980.026
developmental maturationGO:00217001720.026
positive regulation of signal transductionGO:00099672230.026
nucleoside monophosphate metabolic processGO:0009123520.026
protein ubiquitinationGO:0016567700.026
apoptotic processGO:00069151590.026
purine nucleoside monophosphate metabolic processGO:0009126500.026
dna metabolic processGO:00062592270.026
organelle fusionGO:0048284460.026
activation of cysteine type endopeptidase activityGO:0097202170.026
cellular amino acid metabolic processGO:0006520610.025
regulation of growthGO:00400082330.025
intracellular signal transductionGO:00355563000.025
oocyte axis specificationGO:00073091080.025
phagocytosisGO:00069092150.025
organonitrogen compound metabolic processGO:19015643180.025
compound eye developmentGO:00487493070.025
single organism membrane organizationGO:0044802930.024
establishment or maintenance of cell polarityGO:00071631670.024
oocyte differentiationGO:00099941450.024
purine containing compound metabolic processGO:00725211550.024
wing disc morphogenesisGO:00074723440.024
positive regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043280230.024
chemotaxisGO:00069352490.024
regulation of molecular functionGO:00650092170.023
anatomical structure homeostasisGO:0060249970.023
regulation of phosphate metabolic processGO:00192202100.023
establishment of organelle localizationGO:00516561220.023
negative regulation of macromolecule biosynthetic processGO:00105582700.023
cellular component assembly involved in morphogenesisGO:00109271510.023
rna splicing via transesterification reactionsGO:0000375730.023
regulation of nervous system developmentGO:00519602480.023
morphogenesis of an epitheliumGO:00020092760.023
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.023
nucleoside triphosphate metabolic processGO:00091411200.022
positive regulation of protein metabolic processGO:00512471280.022
purine ribonucleotide metabolic processGO:00091501450.022
regulation of cellular protein metabolic processGO:00322682430.022
cytoplasmic transportGO:00164821300.021
meiotic nuclear divisionGO:00071261510.021
mrna processingGO:00063971040.021
cell maturationGO:00484691440.021
purine nucleoside catabolic processGO:00061521120.021
cellular response to radiationGO:0071478520.021
neuron remodelingGO:0016322290.021
sensory organ morphogenesisGO:00905962600.021
positive regulation of cysteine type endopeptidase activityGO:2001056240.020
cellular protein modification processGO:00064644380.020
regulation of multicellular organismal developmentGO:20000264140.020
mrna metabolic processGO:00160711240.020
establishment of localization in cellGO:00516494020.020
regulation of programmed cell deathGO:00430671520.020
positive regulation of rna metabolic processGO:00512542710.020
purine nucleoside metabolic processGO:00422781270.020
imaginal disc derived appendage morphogenesisGO:00351143950.020
nucleobase containing small molecule metabolic processGO:00550861740.020
cell cycle phase transitionGO:00447701400.019
regulation of intracellular signal transductionGO:19025312360.019
protein modification by small protein conjugationGO:0032446790.019
epidermis developmentGO:0008544650.019
nuclear divisionGO:00002803320.019
cellular macromolecule catabolic processGO:00442651360.019
growthGO:00400073590.018
carbohydrate derivative catabolic processGO:19011361180.018
phosphorylationGO:00163102940.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
positive regulation of signalingGO:00230562430.018
purine ribonucleoside triphosphate metabolic processGO:00092051190.018
regulation of proteolysisGO:0030162870.018
regulation of cell proliferationGO:00421271630.018
cellular nitrogen compound catabolic processGO:00442701650.018
protein complex assemblyGO:00064612000.017
ribonucleotide metabolic processGO:00092591450.017
male gamete generationGO:00482322010.017
cellular protein complex assemblyGO:0043623710.017
regulation of phosphorus metabolic processGO:00511742100.017
protein localizationGO:00081042840.017
imaginal disc derived wing morphogenesisGO:00074763370.017
regulation of organelle organizationGO:00330431960.017
single organism intracellular transportGO:19025822070.016
response to oxygen containing compoundGO:19017002000.016
negative regulation of nucleobase containing compound metabolic processGO:00459342610.016
response to extracellular stimulusGO:00099911160.016
regulation of protein metabolic processGO:00512462560.016
response to abiotic stimulusGO:00096283410.016
negative regulation of nitrogen compound metabolic processGO:00511722650.016
positive regulation of rna biosynthetic processGO:19026802660.016
negative regulation of programmed cell deathGO:0043069720.016
regulation of anatomical structure sizeGO:00900661630.016
dendrite morphogenesisGO:00488131990.016
eye photoreceptor cell differentiationGO:00017541450.016
positive regulation of nucleic acid templated transcriptionGO:19035082660.016
regulation of transportGO:00510491810.016
embryonic axis specificationGO:00005781070.016
regulation of immune responseGO:00507761180.016
regulation of defense responseGO:00313471020.016
response to light stimulusGO:00094161240.016
organophosphate metabolic processGO:00196371950.015
cellular homeostasisGO:0019725800.015
axon guidanceGO:00074112330.015
germarium derived egg chamber formationGO:00072931010.015
organelle fissionGO:00482853400.015
neural precursor cell proliferationGO:0061351750.015
instar larval developmentGO:0002168550.015
sex differentiationGO:0007548810.015
response to inorganic substanceGO:0010035440.015
purine nucleoside monophosphate catabolic processGO:0009128380.015
positive regulation of apoptotic processGO:0043065470.015
reproductive structure developmentGO:0048608740.015
negative regulation of rna metabolic processGO:00512532510.014
positive regulation of peptidase activityGO:0010952290.014
photoreceptor cell differentiationGO:00465301700.014
neuron maturationGO:0042551310.014
ribose phosphate metabolic processGO:00196931450.014
negative regulation of cell proliferationGO:0008285690.014
regulation of multi organism processGO:00439001310.014
carbohydrate derivative metabolic processGO:19011352170.014
protein maturationGO:0051604710.014
response to ionizing radiationGO:0010212320.014
stem cell divisionGO:0017145690.014
wnt signaling pathwayGO:0016055980.013
ribonucleotide catabolic processGO:00092611090.013
neuromuscular junction developmentGO:00075281490.013
cell growthGO:00160491080.013
positive regulation of biosynthetic processGO:00098913160.013
mitotic dna damage checkpointGO:0044773740.013
nucleoside catabolic processGO:00091641120.013
positive regulation of wnt signaling pathwayGO:0030177250.013
organophosphate catabolic processGO:00464341120.013
cell cycle arrestGO:000705040.013
negative regulation of erbb signaling pathwayGO:1901185290.013
organelle localizationGO:00516401480.013
body morphogenesisGO:001017120.013
positive regulation of cellular biosynthetic processGO:00313283160.013
cellular catabolic processGO:00442483720.013
larval developmentGO:00021641040.013
regulation of innate immune responseGO:0045088710.013
positive regulation of molecular functionGO:00440931360.013
mitotic cell cycle phase transitionGO:00447721380.013
intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressGO:007005940.012
ribonucleoside monophosphate metabolic processGO:0009161510.012
oocyte constructionGO:00073081120.012
nucleotide catabolic processGO:00091661090.012
regulation of peptidase activityGO:0052547390.012
transmembrane transportGO:00550851390.012
synaptic vesicle localizationGO:0097479530.012
female meiotic divisionGO:0007143700.012
anterior posterior axis specificationGO:00099481090.012
development of primary sexual characteristicsGO:0045137500.012
immune system processGO:00023763470.012
developmental growthGO:00485892800.012
centrosome organizationGO:00512971630.012
gonad developmentGO:0008406500.012
extracellular matrix assemblyGO:0085029130.012
posttranscriptional regulation of gene expressionGO:00106081450.012
cellular response to oxidative stressGO:0034599280.012
regulation of endopeptidase activityGO:0052548360.012
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.012
small gtpase mediated signal transductionGO:0007264880.011
negative regulation of cell differentiationGO:00455961430.011
anterior posterior pattern specificationGO:00099521360.011
g2 dna damage checkpointGO:0031572690.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
regulation of cellular component biogenesisGO:00440872010.011
activation of cysteine type endopeptidase activity involved in apoptotic processGO:0006919160.011
mrna splicing via spliceosomeGO:0000398730.011
cellular respirationGO:0045333260.011
ion transmembrane transportGO:00342201220.011
imaginal disc derived leg segmentationGO:0036011260.011
cytoplasm organizationGO:0007028640.011
axon developmentGO:00615642970.011
centrosome duplicationGO:00512981210.011
energy derivation by oxidation of organic compoundsGO:0015980320.011
ribonucleoside monophosphate catabolic processGO:0009158390.011
response to other organismGO:00517072930.011
organic substance catabolic processGO:19015753080.011
stem cell proliferationGO:0072089880.011
purine ribonucleoside monophosphate catabolic processGO:0009169380.011
vesicle organizationGO:0016050440.011
asymmetric protein localizationGO:0008105330.010
positive regulation of macromolecule biosynthetic processGO:00105572830.010
positive regulation of catalytic activityGO:00430851180.010
negative regulation of mitotic cell cycle phase transitionGO:19019911030.010
post embryonic appendage morphogenesisGO:00351203850.010
actin filament based processGO:00300292200.010
negative regulation of epidermal growth factor receptor signaling pathwayGO:0042059290.010
protein phosphorylationGO:00064681690.010
regulation of cysteine type endopeptidase activityGO:2000116270.010

APP-BP1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.046
cancerDOID:16200.034
disease of cellular proliferationDOID:1456600.034
organ system cancerDOID:005068600.015
nervous system diseaseDOID:86300.015