Drosophila melanogaster

45 known processes

Ork1 (Dmel_CG1615)

Open rectifier K[+] channel 1

(Aliases: anon-WO0161006.1,d-ORK1,KCNK0,anon-WO0161006.22,K[[2P]],anon-WO0161006.23,ORK,ORK1,Dmel\CG1615,dORK,CG1615)

Ork1 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
circadian rhythmGO:00076231050.995
circadian behaviorGO:0048512760.978
rhythmic behaviorGO:0007622760.953
rhythmic processGO:00485111060.950
response to abiotic stimulusGO:00096283410.901
neurological system processGO:00508773580.834
single organism behaviorGO:00447083910.684
cation transportGO:00068121100.621
detection of stimulusGO:00516061560.575
ion transportGO:00068111450.539
multicellular organismal reproductive behaviorGO:00330571100.500
response to radiationGO:00093141550.490
male mating behaviorGO:0060179700.452
response to oxygen containing compoundGO:19017002000.435
regulation of circadian rhythmGO:0042752490.421
mating behaviorGO:00076171060.416
response to light stimulusGO:00094161240.378
multi organism behaviorGO:00517051750.374
locomotor rhythmGO:0045475560.346
sensory perceptionGO:00076001960.338
cognitionGO:00508901410.300
regulation of behaviorGO:0050795750.294
multi multicellular organism processGO:00447061230.285
sleepGO:0030431490.279
regulation of transportGO:00510491810.254
Mouse Rat
locomotory behaviorGO:00076261760.252
regulation of multicellular organismal developmentGO:20000264140.231
taxisGO:00423303040.216
epithelial cell differentiationGO:00308553220.212
developmental growthGO:00485892800.208
cation transmembrane transportGO:0098655880.193
regulation of neurogenesisGO:00507671580.188
response to temperature stimulusGO:00092661060.188
l amino acid importGO:004309220.184
peptide metabolic processGO:0006518800.183
detection of abiotic stimulusGO:0009582660.180
regulation of cell differentiationGO:00455953020.179
organic substance transportGO:00717022570.178
morphogenesis of an epitheliumGO:00020092760.176
reproductive behaviorGO:00190981220.169
regulation of anatomical structure morphogenesisGO:00226032420.168
regulation of ion transportGO:0043269390.165
Mouse Rat
signal releaseGO:0023061490.163
regulation of cellular localizationGO:00603411360.161
synapse organizationGO:00508081960.159
multi organism reproductive behaviorGO:00447051210.158
positive regulation of multicellular organismal processGO:00512401430.155
regulation of localizationGO:00328792750.154
Mouse Rat
cell motilityGO:00488702510.149
detection of stimulus involved in sensory perceptionGO:0050906920.148
positive regulation of response to stimulusGO:00485843230.146
cellular response to hormone stimulusGO:0032870440.140
transmembrane transportGO:00550851390.136
adult chitin containing cuticle pigmentationGO:0048085160.134
regulation of system processGO:0044057360.131
matingGO:00076181200.131
organonitrogen compound metabolic processGO:19015643180.131
carboxylic acid transportGO:0046942180.130
secretionGO:00469031090.130
central nervous system developmentGO:00074172010.128
negative regulation of macromolecule biosynthetic processGO:00105582700.127
organelle fissionGO:00482853400.127
response to biotic stimulusGO:00096072940.127
striated muscle cell differentiationGO:0051146900.126
cellular amide metabolic processGO:0043603800.125
apoptotic processGO:00069151590.125
ion transmembrane transportGO:00342201220.124
appendage morphogenesisGO:00351073970.121
response to other organismGO:00517072930.121
organic acid metabolic processGO:00060821030.120
small molecule metabolic processGO:00442813050.117
response to external biotic stimulusGO:00432072930.117
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.115
regulation of heart rateGO:0002027110.115
detection of external stimulusGO:0009581660.114
synaptic growth at neuromuscular junctionGO:00511241190.113
regionalizationGO:00030024160.112
establishment of localization in cellGO:00516494020.111
columnar cuboidal epithelial cell differentiationGO:00020652560.110
homeostatic processGO:00425921990.107
negative regulation of nitrogen compound metabolic processGO:00511722650.106
response to inorganic substanceGO:0010035440.105
positive regulation of axon guidanceGO:190266910.105
nitrogen compound transportGO:0071705850.103
negative regulation of nucleic acid templated transcriptionGO:19035072400.101
response to hypoxiaGO:0001666530.100
response to organic substanceGO:00100332840.100
cellular protein modification processGO:00064644380.100
cellular catabolic processGO:00442483720.098
regulation of blood circulationGO:1903522210.098
negative regulation of transcription dna templatedGO:00458922370.097
defense response to bacteriumGO:00427421780.097
positive regulation of macromolecule metabolic processGO:00106044050.096
response to nitrogen compoundGO:1901698900.096
response to organophosphorusGO:004668320.096
growthGO:00400073590.095
single organism cellular localizationGO:19025801800.095
regulation of secretion by cellGO:1903530390.094
axon guidanceGO:00074112330.092
positive regulation of cell differentiationGO:0045597640.092
regulation of protein metabolic processGO:00512462560.091
localization of cellGO:00516742570.090
positive regulation of developmental processGO:00510941430.090
muscle structure developmentGO:00610612240.090
positive regulation of rna metabolic processGO:00512542710.090
immune responseGO:00069552460.089
positive regulation of signal transductionGO:00099672230.086
regulation of secretionGO:0051046440.085
organic acid transportGO:0015849180.085
protein complex assemblyGO:00064612000.085
negative regulation of rna biosynthetic processGO:19026792400.084
positive regulation of signalingGO:00230562430.084
response to metal ionGO:0010038230.083
secretion by cellGO:00329401010.080
brain developmentGO:00074201200.080
cellular response to peptide hormone stimulusGO:0071375280.077
macromolecular complex assemblyGO:00650032560.076
cell migrationGO:00164772380.076
catabolic processGO:00090564090.076
regulation of chitin based cuticle tanningGO:0007564140.076
developmental maturationGO:00217001720.075
positive regulation of cellular component organizationGO:00511301560.075
cellular macromolecule localizationGO:00707272200.075
negative regulation of rna metabolic processGO:00512532510.075
response to endogenous stimulusGO:00097191190.075
response to glucoseGO:000974920.073
organic substance catabolic processGO:19015753080.073
sulfur compound metabolic processGO:0006790590.073
eye photoreceptor cell differentiationGO:00017541450.072
response to hexoseGO:000974630.072
chemotaxisGO:00069352490.072
response to painGO:004826530.071
agingGO:00075681430.071
learningGO:0007612750.071
protein modification processGO:00362114380.070
cellular response to abiotic stimulusGO:0071214580.070
muscle cell differentiationGO:00426921030.069
regulation of transcription from rna polymerase ii promoterGO:00063573780.069
male courtship behaviorGO:0008049630.069
appendage developmentGO:00487364010.068
cellular response to chemical stimulusGO:00708871990.067
positive regulation of cell communicationGO:00106472500.067
camera type eye developmentGO:004301040.066
synapse assemblyGO:00074161430.066
negative regulation of biosynthetic processGO:00098902770.064
endomembrane system organizationGO:00102561190.064
antimicrobial humoral responseGO:0019730990.064
regulation of cell developmentGO:00602842150.062
cuticle developmentGO:0042335860.062
neuropeptide signaling pathwayGO:0007218450.061
circadian sleep wake cycleGO:0042745280.059
positive regulation of secretionGO:0051047220.058
regulation of cuticle pigmentationGO:0048079160.057
protein complex biogenesisGO:00702712010.057
defense response to other organismGO:00985422250.057
neuromuscular junction developmentGO:00075281490.057
organelle localizationGO:00516401480.057
negative regulation of signal transductionGO:00099682060.057
intracellular transportGO:00469072280.056
regulation of cell projection organizationGO:0031344920.056
nuclear divisionGO:00002803320.056
tube developmentGO:00352952440.056
single organism biosynthetic processGO:00447112060.055
axonogenesisGO:00074092900.054
positive regulation of nitrogen compound metabolic processGO:00511733540.054
phosphorylationGO:00163102940.054
monocarboxylic acid transportGO:001571830.054
learning or memoryGO:00076111410.054
head developmentGO:00603221350.053
eye developmentGO:00016543230.053
positive regulation of lipid metabolic processGO:004583440.053
regulation of hormone levelsGO:0010817400.052
stem cell differentiationGO:00488631170.052
dendrite morphogenesisGO:00488131990.052
cuticle pigmentationGO:0048067220.051
inter male aggressive behaviorGO:0002121600.050
gastrulation with mouth forming firstGO:0001703360.050
transcription from rna polymerase ii promoterGO:00063663680.050
negative regulation of cellular biosynthetic processGO:00313272770.050
metal ion transportGO:0030001740.050
chemical homeostasisGO:0048878920.049
amine metabolic processGO:0009308120.048
cellular response to insulin stimulusGO:0032869280.048
tube morphogenesisGO:00352391910.048
regulation of cellular response to insulin stimulusGO:1900076170.048
positive regulation of gene expressionGO:00106282900.048
tissue morphogenesisGO:00487292970.047
dendrite developmentGO:00163582040.047
organic anion transportGO:0015711280.047
gliogenesisGO:0042063800.046
humoral immune responseGO:00069591170.046
response to monosaccharideGO:003428440.046
regulation of cell morphogenesisGO:00226041630.046
cellular response to organic substanceGO:00713101320.045
enzyme linked receptor protein signaling pathwayGO:00071671790.045
cellular amino acid metabolic processGO:0006520610.045
response to insulinGO:0032868290.045
cellular homeostasisGO:0019725800.045
establishment of organelle localizationGO:00516561220.044
response to organic cyclic compoundGO:0014070890.044
positive regulation of neurogenesisGO:0050769410.043
courtship behaviorGO:0007619680.043
cellular response to nitrogen compoundGO:1901699510.043
regulation of cellular protein metabolic processGO:00322682430.042
response to bacteriumGO:00096171980.042
immune system processGO:00023763470.042
protein localizationGO:00081042840.042
regulation of nervous system developmentGO:00519602480.041
spermatogenesisGO:00072832000.041
neuron recognitionGO:00080381010.041
regulation of heart contractionGO:0008016210.041
gene silencingGO:00164581380.041
oxoacid metabolic processGO:00434361030.040
glandular epithelial cell differentiationGO:000206710.040
neuron projection guidanceGO:00974852410.040
negative regulation of transcription from rna polymerase ii promoterGO:00001221190.040
heart processGO:0003015370.040
anion transportGO:0006820410.040
determination of adult lifespanGO:00083401370.039
regulation of molecular functionGO:00650092170.039
regulation of tor signalingGO:0032006210.039
inorganic ion transmembrane transportGO:0098660730.039
cellular chemical homeostasisGO:0055082400.039
digestive system developmentGO:00551231490.039
regulation of organ morphogenesisGO:2000027780.039
regulation of epithelial cell proliferationGO:005067840.039
amino acid transportGO:0006865120.039
actin filament based processGO:00300292200.039
regulation of membrane potentialGO:0042391350.039
Mouse
post embryonic appendage morphogenesisGO:00351203850.038
camera type eye morphogenesisGO:004859320.038
cellular response to oxygen containing compoundGO:1901701790.038
molting cycle processGO:0022404290.037
striated muscle cell developmentGO:0055002500.037
regulation of synapse structure and activityGO:00508031280.036
urogenital system developmentGO:0001655720.036
ethanolamine containing compound metabolic processGO:004243940.036
extracellular structure organizationGO:0043062460.036
axon developmentGO:00615642970.035
metal ion homeostasisGO:0055065440.035
carboxylic acid metabolic processGO:0019752920.035
single organism intracellular transportGO:19025822070.034
embryonic pattern specificationGO:00098801740.034
deathGO:00162652840.034
interspecies interaction between organismsGO:0044419160.034
male courtship behavior veined wing generated song productionGO:0045433200.034
negative regulation of cellular component organizationGO:00511291080.033
digestive tract morphogenesisGO:00485461270.033
catecholamine biosynthetic processGO:004242330.033
response to decreased oxygen levelsGO:0036293580.033
negative regulation of cell differentiationGO:00455961430.033
circadian sleep wake cycle sleepGO:0050802230.033
regulation of cell sizeGO:0008361630.032
photoreceptor cell developmentGO:0042461960.032
compound eye photoreceptor developmentGO:0042051780.032
negative regulation of gene expressionGO:00106293870.032
enteroendocrine cell differentiationGO:003588310.032
mitotic spindle organizationGO:00070522200.031
regulation of response to stressGO:00801342000.031
epithelial cell developmentGO:00020642740.031
imaginal disc derived appendage morphogenesisGO:00351143950.030
cellular response to endogenous stimulusGO:0071495800.030
cellular response to carbohydrate stimulusGO:007132240.030
l glutamate importGO:005193810.030
cell recognitionGO:00080371020.030
regulation of circadian sleep wake cycleGO:0042749250.030
cell growthGO:00160491080.030
molting cycle chitin based cuticleGO:0007591560.029
extracellular matrix organizationGO:0030198320.029
mitotic nuclear divisionGO:00070672130.029
cell fate determinationGO:0001709910.028
protein complex disassemblyGO:0043241360.028
response to organonitrogen compoundGO:0010243750.028
cellular response to monosaccharide stimulusGO:007132620.028
defense response to gram negative bacteriumGO:0050829940.028
mitochondrion organizationGO:0007005650.028
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.028
cellular amine metabolic processGO:0044106120.028
positive regulation of cell motilityGO:200014730.027
intraspecies interaction between organismsGO:005170340.027
macromolecule catabolic processGO:00090571610.027
negative regulation of cellular protein metabolic processGO:0032269850.027
ovarian follicle cell developmentGO:00307072480.027
chaeta developmentGO:0022416970.027
wound healing spreading of epidermal cellsGO:003531310.027
columnar cuboidal epithelial cell developmentGO:00020662490.027
imaginal disc derived appendage developmentGO:00487373990.027
sensory organ precursor cell fate determinationGO:0016360190.027
mesenchymal cell differentiationGO:004876210.027
epithelial tube morphogenesisGO:0060562880.027
defense response to fungusGO:0050832480.027
positive regulation of biosynthetic processGO:00098913160.027
regulation of immune system processGO:00026821760.026
stem cell developmentGO:0048864790.026
positive regulation of nucleic acid templated transcriptionGO:19035082660.026
renal system developmentGO:0072001720.026
regulation of synaptic transmissionGO:0050804690.025
detection of mechanical stimulus involved in sensory perception of painGO:005096620.025
gene silencing by rnaGO:0031047570.025
rna localizationGO:00064031150.025
ovipositionGO:0018991190.025
behavioral response to painGO:004826630.025
malpighian tubule morphogenesisGO:0007443440.025
positive regulation of transcription dna templatedGO:00458932660.025
regulation of organelle organizationGO:00330431960.024
response to oxygen levelsGO:0070482590.024
carbohydrate homeostasisGO:0033500120.024
negative regulation of cellular metabolic processGO:00313243820.024
synaptic transmissionGO:00072682880.024
cellular component disassemblyGO:0022411460.024
single organism catabolic processGO:00447122280.024
regulation of neuron differentiationGO:00456641030.024
muscle cell developmentGO:0055001500.024
negative regulation of nucleobase containing compound metabolic processGO:00459342610.024
mesenchymal cell developmentGO:001403110.024
circulatory system developmentGO:0072359820.023
phagocytosisGO:00069092150.023
programmed cell deathGO:00125012570.023
chitin based cuticle sclerotizationGO:0007593190.023
regulation of circadian sleep wake cycle sleepGO:0045187210.023
regulation of cellular ketone metabolic processGO:001056530.023
limb developmentGO:006017310.023
cardiovascular system developmentGO:0072358820.022
organophosphate metabolic processGO:00196371950.022
cellular protein localizationGO:00346131600.022
cellular lipid metabolic processGO:0044255830.022
innate immune responseGO:00450871440.022
regulation of adult chitin containing cuticle pigmentationGO:0048082130.022
aggressive behaviorGO:0002118630.022
adult locomotory behaviorGO:0008344760.022
regulation of neuron deathGO:1901214260.022
glycoprotein biosynthetic processGO:0009101410.022
photoreceptor cell differentiationGO:00465301700.022
multicellular organismal response to stressGO:003355550.022
phenol containing compound metabolic processGO:0018958570.022
body morphogenesisGO:001017120.022
mushroom body developmentGO:0016319700.022
mitotic cell cycle phase transitionGO:00447721380.022
embryonic morphogenesisGO:00485982060.022
response to drugGO:0042493170.022
protein depolymerizationGO:0051261310.021
organic cyclic compound catabolic processGO:19013611680.021
ion homeostasisGO:0050801550.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
wing disc morphogenesisGO:00074723440.021
positive regulation of developmental growthGO:0048639620.021
digestive tract developmentGO:00485651490.021
drinking behaviorGO:004275620.021
chorion containing eggshell formationGO:00073041050.021
positive regulation of intracellular signal transductionGO:19025331160.021
chromosome organizationGO:00512763600.021
cellular protein complex disassemblyGO:0043624350.021
calcium ion transportGO:0006816240.021
heart developmentGO:0007507820.021
phosphatidylinositol mediated signalingGO:004801540.021
immune response activating signal transductionGO:000275720.020
regulation of cellular amine metabolic processGO:003323830.020
dorsal ventral pattern formationGO:00099531330.020
negative regulation of developmental processGO:00510932010.020
defense responseGO:00069523000.020
cellular ion homeostasisGO:0006873390.020
regulation of cellular response to stressGO:0080135890.020
circadian sleep wake cycle processGO:0022410240.020
positive regulation of secretion by cellGO:1903532200.020
regulation of catabolic processGO:00098941700.020
cellularizationGO:0007349900.020
positive regulation of molecular functionGO:00440931360.020
positive regulation of peptidyl tyrosine phosphorylationGO:005073140.019
single organism carbohydrate metabolic processGO:0044723720.019
eggshell chorion assemblyGO:0007306660.019
lipid storageGO:0019915380.019
limb morphogenesisGO:003510810.019
meiotic cell cycleGO:00513211710.019
rna catabolic processGO:0006401370.019
cellular macromolecular complex assemblyGO:00346221530.019
lipid metabolic processGO:00066291210.019
hemopoiesisGO:0030097460.019
carbohydrate metabolic processGO:0005975820.019
regulation of synaptic growth at neuromuscular junctionGO:0008582890.019
negative regulation of cell communicationGO:00106482230.018
eye morphogenesisGO:00485922600.018
cation homeostasisGO:0055080510.018
glycoprotein metabolic processGO:0009100410.018
positive regulation of transportGO:0051050920.018
regulation of programmed cell deathGO:00430671520.018
proteolysis involved in cellular protein catabolic processGO:0051603830.018
intracellular signal transductionGO:00355563000.018
response to toxic substanceGO:0009636220.018
multicellular organismal agingGO:00102591400.018
myotube cell developmentGO:001490430.018
oxidation reduction processGO:00551141230.018
eggshell formationGO:00307031050.018
synaptic vesicle localizationGO:0097479530.018
proteolysisGO:00065081920.018
embryonic heart tube developmentGO:0035050220.018
negative regulation of multicellular organismal processGO:00512411420.018
cellular response to decreased oxygen levelsGO:0036294300.018
regulation of neuron projection developmentGO:0010975690.017
lipid biosynthetic processGO:0008610460.017
compound eye photoreceptor cell differentiationGO:00017511400.017
regulation of protein modification processGO:00313991120.017
secondary metabolic processGO:0019748750.017
small molecule biosynthetic processGO:0044283370.017
response to alkaloidGO:0043279260.017
adult behaviorGO:00305341370.017
regulation of innate immune responseGO:0045088710.017
protein localization to organelleGO:0033365820.017
g protein coupled receptor signaling pathwayGO:00071861360.017
Mouse
dna integrity checkpointGO:0031570810.017
ovarian follicle cell migrationGO:00072971210.017
anion homeostasisGO:005508130.017
sensory perception of painGO:001923340.017
erk1 and erk2 cascadeGO:0070371390.017
phototaxisGO:0042331210.017
positive regulation of behaviorGO:0048520190.017
regulation of phosphorylationGO:00423251470.017
cell maturationGO:00484691440.017
negative regulation of cell developmentGO:0010721620.016
cellular nitrogen compound catabolic processGO:00442701650.016
negative regulation of synapse assemblyGO:0051964390.016
purine containing compound catabolic processGO:00725231120.016
inositol lipid mediated signalingGO:004801740.016
cellular macromolecule catabolic processGO:00442651360.016
catechol containing compound biosynthetic processGO:000971330.016
positive regulation of rna biosynthetic processGO:19026802660.016
sensory perception of soundGO:0007605560.016
positive regulation of immune responseGO:0050778630.016
macromolecular complex disassemblyGO:0032984370.016
positive regulation of defense responseGO:0031349590.016
positive regulation of dendrite morphogenesisGO:005077590.016
regulation of cell deathGO:00109411730.016
regulation of phosphorus metabolic processGO:00511742100.016
positive regulation of cell developmentGO:0010720610.016
carbohydrate derivative biosynthetic processGO:1901137850.016
response to heatGO:0009408630.016
polyol biosynthetic processGO:004617330.016
regulation of reproductive processGO:2000241540.016
kidney developmentGO:000182230.016
positive regulation of canonical wnt signaling pathwayGO:009026370.016
response to lipopolysaccharideGO:003249640.016
cellular response to hexose stimulusGO:007133110.016
regulation of synapse organizationGO:00508071100.016
negative regulation of signalingGO:00230572190.016
purine containing compound metabolic processGO:00725211550.015
imaginal disc derived wing morphogenesisGO:00074763370.015
phosphatidylinositol 3 kinase signalingGO:001406540.015
striated muscle tissue developmentGO:0014706270.015
positive regulation of nucleobase containing compound metabolic processGO:00459353320.015
cranial nerve developmentGO:002154510.015
aromatic compound catabolic processGO:00194391660.015
regulation of intracellular signal transductionGO:19025312360.015
regulation of epithelial cell differentiationGO:003085640.015
regulation of anatomical structure sizeGO:00900661630.015
muscle organ developmentGO:00075171270.015
endocytosisGO:00068973100.015
regulation of immune responseGO:00507761180.015
ribose phosphate metabolic processGO:00196931450.015
positive regulation of gliogenesisGO:001401550.015
cell agingGO:000756920.015
establishment of protein localizationGO:00451841630.015
forebrain developmentGO:003090020.015
anatomical structure homeostasisGO:0060249970.015
dorsal appendage formationGO:0046843470.015
sensory perception of chemical stimulusGO:00076061160.015
regulation of neurotransmitter levelsGO:0001505380.015
muscle tissue developmentGO:0060537300.015
embryo development ending in birth or egg hatchingGO:00097921520.015
intracellular receptor signaling pathwayGO:0030522190.015
hindbrain developmentGO:003090220.015
maintenance of locationGO:0051235730.015
gastrulation involving germ band extensionGO:0010004360.015
response to hormoneGO:0009725450.015
border follicle cell migrationGO:00072981130.014
sterol homeostasisGO:005509240.014
insulin receptor signaling pathwayGO:0008286250.014
gastrulationGO:0007369700.014
nucleotide catabolic processGO:00091661090.014
posttranscriptional gene silencingGO:0016441460.014
glycerolipid catabolic processGO:004650330.014
negative regulation of protein metabolic processGO:0051248850.014
collateral sproutingGO:004866830.014
protein catabolic processGO:00301631010.014

Ork1 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
disease of anatomical entityDOID:700.168
acquired metabolic diseaseDOID:006015800.088
carbohydrate metabolism diseaseDOID:005001300.088
diabetes mellitusDOID:935100.088
disease of metabolismDOID:001466700.088
glucose metabolism diseaseDOID:419400.088
inherited metabolic disorderDOID:65500.072
nervous system diseaseDOID:86300.036
kidney diseaseDOID:55700.023
urinary system diseaseDOID:1800.023
type 2 diabetes mellitusDOID:935200.020
cardiovascular system diseaseDOID:128700.017
musculoskeletal system diseaseDOID:1700.015
artery diseaseDOID:005082800.014
hypertensionDOID:1076300.014
essential hypertensionDOID:1082500.014
vascular diseaseDOID:17800.014