Drosophila melanogaster

53 known processes

pll (Dmel_CG5974)

pelle

(Aliases: p11,PELLE/IL-1,CG5974,Dmel\CG5974)

pll biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
actin cytoskeleton organizationGO:00300362060.550
embryo development ending in birth or egg hatchingGO:00097921520.534
regulation of response to external stimulusGO:00321011150.478
axonogenesisGO:00074092900.463
peptide metabolic processGO:0006518800.433
defense response to other organismGO:00985422250.378
intracellular signal transductionGO:00355563000.303
Human
chemotaxisGO:00069352490.296
response to fungusGO:0009620500.287
antifungal humoral responseGO:0019732120.274
response to organic substanceGO:00100332840.268
Mouse
synaptic growth at neuromuscular junctionGO:00511241190.268
regulation of cellular component biogenesisGO:00440872010.267
defense responseGO:00069523000.259
embryonic development via the syncytial blastodermGO:00017001480.253
positive regulation of cellular component biogenesisGO:0044089800.251
immune system processGO:00023763470.239
tissue morphogenesisGO:00487292970.226
positive regulation of response to stimulusGO:00485843230.224
Human
neuron projection guidanceGO:00974852410.224
organelle localizationGO:00516401480.214
actin filament based processGO:00300292200.214
branching morphogenesis of an epithelial tubeGO:0048754450.213
regulation of cell deathGO:00109411730.209
regionalizationGO:00030024160.200
embryonic morphogenesisGO:00485982060.181
defense response to bacteriumGO:00427421780.174
organonitrogen compound metabolic processGO:19015643180.172
regulation of neurogenesisGO:00507671580.170
positive regulation of cell migrationGO:003033520.165
regulation of response to stressGO:00801342000.157
circulatory system developmentGO:0072359820.156
regulation of cell developmentGO:00602842150.154
regulation of intracellular signal transductionGO:19025312360.153
Human
imaginal disc derived appendage morphogenesisGO:00351143950.153
negative regulation of rna metabolic processGO:00512532510.152
synapse organizationGO:00508081960.151
cell projection assemblyGO:0030031940.146
positive regulation of response to external stimulusGO:0032103440.143
post embryonic appendage morphogenesisGO:00351203850.139
response to radiationGO:00093141550.130
morphogenesis of an epitheliumGO:00020092760.126
axon guidanceGO:00074112330.125
regulation of cell differentiationGO:00455953020.125
taxisGO:00423303040.123
developmental maturationGO:00217001720.122
regulation of cytoskeleton organizationGO:0051493890.121
single organismal cell cell adhesionGO:0016337450.121
imaginal disc derived wing morphogenesisGO:00074763370.119
catabolic processGO:00090564090.119
regulation of apoptotic processGO:00429811300.117
cellular protein modification processGO:00064644380.113
positive regulation of antimicrobial humoral responseGO:0002760280.110
secretion by cellGO:00329401010.107
histone modificationGO:00165701060.106
organic acid metabolic processGO:00060821030.102
regulation of cell projection organizationGO:0031344920.102
actin filament organizationGO:00070151260.101
regulation of immune system processGO:00026821760.100
negative regulation of nucleic acid templated transcriptionGO:19035072400.099
single organism cellular localizationGO:19025801800.095
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.092
regulation of neuron projection developmentGO:0010975690.092
response to abiotic stimulusGO:00096283410.089
regulation of localizationGO:00328792750.088
response to nitrogen compoundGO:1901698900.088
single organism cell adhesionGO:0098602470.087
nephron epithelium developmentGO:007200930.087
axon developmentGO:00615642970.087
macromolecular complex assemblyGO:00650032560.087
response to other organismGO:00517072930.086
negative regulation of response to stimulusGO:00485852580.085
cellular response to chemical stimulusGO:00708871990.085
Mouse
axis specificationGO:00097981670.084
protein modification processGO:00362114380.084
positive regulation of phosphate metabolic processGO:00459371390.081
cell motilityGO:00488702510.081
regulation of notch signaling pathwayGO:00085931000.081
phagocytosisGO:00069092150.080
regulation of synapse assemblyGO:0051963940.079
muscle structure developmentGO:00610612240.079
cellular lipid metabolic processGO:0044255830.078
immune effector processGO:0002252980.078
oxoacid metabolic processGO:00434361030.078
phosphorylationGO:00163102940.078
positive regulation of cell developmentGO:0010720610.078
response to biotic stimulusGO:00096072940.076
negative regulation of signalingGO:00230572190.075
regulation of muscle organ developmentGO:0048634130.074
lamellipodium organizationGO:0097581210.073
dendrite morphogenesisGO:00488131990.073
synapse assemblyGO:00074161430.071
immune responseGO:00069552460.071
regulation of cellular component movementGO:0051270420.070
positive regulation of phosphorus metabolic processGO:00105621390.070
response to external biotic stimulusGO:00432072930.070
positive regulation of nitrogen compound metabolic processGO:00511733540.068
regulation of cell morphogenesisGO:00226041630.068
notch signaling pathwayGO:00072191200.068
oocyte dorsal ventral axis specificationGO:0007310340.068
negative regulation of signal transductionGO:00099682060.068
regulation of protein metabolic processGO:00512462560.067
regulation of proteolysisGO:0030162870.067
organic substance catabolic processGO:19015753080.067
positive regulation of cellular component organizationGO:00511301560.067
regulation of cell morphogenesis involved in differentiationGO:0010769610.067
positive regulation of signalingGO:00230562430.065
Human
deathGO:00162652840.063
positive regulation of cell communicationGO:00106472500.061
Human
protein transportGO:00150311550.061
regulation of synapse organizationGO:00508071100.061
regulation of anatomical structure sizeGO:00900661630.060
regulation of locomotionGO:0040012420.059
regulation of defense response to fungusGO:190015060.059
transcription from rna polymerase ii promoterGO:00063663680.058
proteolysisGO:00065081920.058
nucleobase containing small molecule metabolic processGO:00550861740.056
dendrite developmentGO:00163582040.055
oocyte differentiationGO:00099941450.054
cell junction organizationGO:0034330570.054
imaginal disc derived appendage developmentGO:00487373990.053
positive regulation of cell motilityGO:200014730.053
cell deathGO:00082192790.053
kidney epithelium developmentGO:007207330.052
motor neuron axon guidanceGO:0008045580.052
cell recognitionGO:00080371020.052
small molecule metabolic processGO:00442813050.051
positive regulation of signal transductionGO:00099672230.051
Human
establishment of protein localizationGO:00451841630.051
carboxylic acid metabolic processGO:0019752920.050
negative regulation of macromolecule biosynthetic processGO:00105582700.050
dorsal ventral pattern formationGO:00099531330.050
respiratory system developmentGO:00605412130.050
regulation of anatomical structure morphogenesisGO:00226032420.049
positive regulation of cell deathGO:0010942690.049
neuromuscular junction developmentGO:00075281490.049
sensory perception of mechanical stimulusGO:0050954720.049
regulation of defense responseGO:00313471020.048
regulation of multicellular organismal developmentGO:20000264140.048
camera type eye developmentGO:004301040.048
kidney developmentGO:000182230.047
extrinsic apoptotic signaling pathwayGO:009719110.047
regulation of immune responseGO:00507761180.046
cell activationGO:000177590.045
cell adhesionGO:00071551360.044
cellular macromolecule localizationGO:00707272200.044
tube morphogenesisGO:00352391910.044
cellular amide metabolic processGO:0043603800.043
secretionGO:00469031090.043
regulation of actin filament based processGO:0032970420.043
response to organonitrogen compoundGO:0010243750.043
cellular response to organic substanceGO:00713101320.043
Mouse
establishment or maintenance of cell polarityGO:00071631670.042
organonitrogen compound biosynthetic processGO:19015661170.041
positive regulation of immune system processGO:0002684680.041
response to transforming growth factor betaGO:0071559180.041
gland morphogenesisGO:00226121450.041
cardiovascular system developmentGO:0072358820.040
single organism behaviorGO:00447083910.040
cellular response to abiotic stimulusGO:0071214580.040
positive regulation of rna biosynthetic processGO:19026802660.040
protein complex assemblyGO:00064612000.039
biological adhesionGO:00226101380.039
positive regulation of programmed cell deathGO:0043068620.038
open tracheal system developmentGO:00074242040.038
ameboidal type cell migrationGO:00016671510.038
eye developmentGO:00016543230.037
protein phosphorylationGO:00064681690.037
regulation of cellular amine metabolic processGO:003323830.037
morphogenesis of a branching epitheliumGO:0061138450.036
negative regulation of nitrogen compound metabolic processGO:00511722650.036
defense response to gram negative bacteriumGO:0050829940.036
tube developmentGO:00352952440.036
positive regulation of nucleobase containing compound metabolic processGO:00459353320.036
regulation of cellular amide metabolic processGO:0034248390.036
connective tissue developmentGO:006144830.035
regulation of cellular protein metabolic processGO:00322682430.035
cell cell junction organizationGO:0045216550.035
positive regulation of nucleic acid templated transcriptionGO:19035082660.035
regulation of nervous system developmentGO:00519602480.035
regulation of cellular response to growth factor stimulusGO:0090287130.035
humoral immune responseGO:00069591170.034
oocyte developmentGO:00485991240.034
regulation of protein complex assemblyGO:0043254420.034
single organism biosynthetic processGO:00447112060.033
maternal specification of dorsal ventral axis oocyte germ line encodedGO:000731140.033
cellular catabolic processGO:00442483720.033
cellular protein complex assemblyGO:0043623710.033
enzyme linked receptor protein signaling pathwayGO:00071671790.033
epithelial tube morphogenesisGO:0060562880.032
regulation of cellular component sizeGO:0032535980.032
regulation of actin cytoskeleton organizationGO:0032956420.032
cellular protein catabolic processGO:0044257830.032
protein catabolic processGO:00301631010.032
cell migrationGO:00164772380.032
positive regulation of phosphorylationGO:0042327870.032
negative regulation of cellular metabolic processGO:00313243820.032
vesicle mediated transportGO:00161923810.031
morphogenesis of embryonic epitheliumGO:0016331940.031
anterior posterior axis specificationGO:00099481090.031
negative regulation of programmed cell deathGO:0043069720.031
organophosphate metabolic processGO:00196371950.031
cell type specific apoptotic processGO:0097285380.031
negative regulation of rna biosynthetic processGO:19026792400.030
heart developmentGO:0007507820.030
protein localizationGO:00081042840.029
protein maturationGO:0051604710.029
regulation of cell substrate adhesionGO:001081020.029
protein complex biogenesisGO:00702712010.029
cellular response to external stimulusGO:0071496660.029
positive regulation of intracellular signal transductionGO:19025331160.029
Human
negative regulation of cell communicationGO:00106482230.028
regulation of cellular catabolic processGO:00313291570.028
lamellipodium assemblyGO:0030032210.028
innate immune responseGO:00450871440.028
cell maturationGO:00484691440.028
lipid modificationGO:0030258240.028
regulation of stress activated protein kinase signaling cascadeGO:0070302420.028
nucleoside phosphate metabolic processGO:00067531620.027
dorsal closureGO:0007391790.027
lipid biosynthetic processGO:0008610460.027
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.027
chromosome organizationGO:00512763600.026
regulation of cell sizeGO:0008361630.026
regulation of immune effector processGO:0002697520.026
urogenital system developmentGO:0001655720.026
positive regulation of biosynthetic processGO:00098913160.026
negative regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090101180.026
positive regulation of multicellular organismal processGO:00512401430.026
establishment of localization in cellGO:00516494020.026
negative regulation of transforming growth factor beta receptor signaling pathwayGO:003051240.025
dorsal ventral axis specificationGO:0009950660.025
covalent chromatin modificationGO:00165691060.025
actin cytoskeleton reorganizationGO:0031532220.025
positive regulation of apoptotic processGO:0043065470.025
rho protein signal transductionGO:0007266140.025
response to nutrient levelsGO:00316671140.025
nucleotide metabolic processGO:00091171610.025
ribonucleoside triphosphate metabolic processGO:00091991190.024
regulation of cellular amino acid metabolic processGO:000652100.024
somatic muscle developmentGO:0007525660.024
positive regulation of cytoskeleton organizationGO:0051495210.024
positive regulation of antifungal peptide productionGO:000280460.024
small gtpase mediated signal transductionGO:0007264880.024
exocrine system developmentGO:00352721620.023
regulation of response to woundingGO:1903034190.023
sex differentiationGO:0007548810.023
mapk cascadeGO:00001651070.023
synaptic transmissionGO:00072682880.023
oocyte axis specificationGO:00073091080.023
positive regulation of antifungal peptide biosynthetic processGO:000696750.023
cellular amine metabolic processGO:0044106120.022
antimicrobial peptide productionGO:0002775460.022
rna processingGO:00063961470.022
sensory organ morphogenesisGO:00905962600.022
regulation of phosphorus metabolic processGO:00511742100.022
negative regulation of notch signaling pathwayGO:0045746410.022
positive regulation of neurogenesisGO:0050769410.022
response to bacteriumGO:00096171980.022
regulation of synapse structure and activityGO:00508031280.022
negative regulation of cell deathGO:0060548810.022
appendage morphogenesisGO:00351073970.022
negative regulation of nucleobase containing compound metabolic processGO:00459342610.022
endocytosisGO:00068973100.021
macromolecule catabolic processGO:00090571610.021
organic substance transportGO:00717022570.021
cell proliferationGO:00082832990.021
positive regulation of developmental processGO:00510941430.021
positive regulation of cell differentiationGO:0045597640.021
programmed cell deathGO:00125012570.021
cell fate commitment involved in pattern specificationGO:0060581310.021
regulation of jnk cascadeGO:0046328400.021
positive regulation of organelle organizationGO:0010638650.021
regulation of retinal cell programmed cell deathGO:0046668180.021
positive regulation of cellular protein metabolic processGO:00322701180.021
renal tubule developmentGO:0061326640.021
regulation of antifungal peptide productionGO:000278860.021
mesenchymal cell differentiationGO:004876210.021
ubiquitin dependent protein catabolic processGO:0006511780.020
pseudocleavageGO:003058890.020
regulation of neuron differentiationGO:00456641030.020
positive regulation of mapk cascadeGO:0043410630.020
single organism catabolic processGO:00447122280.020
antimicrobial humoral responseGO:0019730990.020
regulation of actin polymerization or depolymerizationGO:0008064270.020
oxidation reduction processGO:00551141230.020
protein localization to nucleusGO:0034504550.020
negative regulation of biosynthetic processGO:00098902770.020
positive regulation of gene expressionGO:00106282900.020
protein polymerizationGO:0051258420.020
regulation of wnt signaling pathwayGO:0030111680.020
positive regulation of transcription dna templatedGO:00458932660.020
regulation of dna metabolic processGO:0051052340.020
positive regulation of catabolic processGO:00098961050.020
regulation of protein localizationGO:0032880760.020
fertilizationGO:0009566260.020
organelle assemblyGO:00709251980.020
appendage developmentGO:00487364010.020
organonitrogen compound catabolic processGO:19015651280.020
regulation of transcription from rna polymerase ii promoterGO:00063573780.020
regulation of protein secretionGO:0050708130.019
positive regulation of protein complex assemblyGO:0031334220.019
regulation of cell motilityGO:2000145230.019
malpighian tubule developmentGO:0072002640.019
retinal cell programmed cell deathGO:0046666250.019
regulation of response to biotic stimulusGO:0002831630.019
negative regulation of cellular biosynthetic processGO:00313272770.019
regulation of catabolic processGO:00098941700.019
apoptotic processGO:00069151590.019
mitotic cell cycle phase transitionGO:00447721380.019
axon extensionGO:0048675320.019
gland developmentGO:00487321910.019
ras protein signal transductionGO:0007265880.018
regulation of autophagyGO:0010506620.018
toll signaling pathwayGO:0008063250.018
positive regulation of molecular functionGO:00440931360.018
defense response to fungusGO:0050832480.018
regulation of catalytic activityGO:00507901850.018
positive regulation of multi organism processGO:0043902400.018
ribonucleotide metabolic processGO:00092591450.018
response to endogenous stimulusGO:00097191190.018
neuron projection extensionGO:1990138320.018
epithelial cell developmentGO:00020642740.018
regulation of phosphorylationGO:00423251470.018
muscle cell migrationGO:001481230.018
autophagyGO:00069141080.018
oocyte constructionGO:00073081120.018
regulation of cellular localizationGO:00603411360.018
protein processingGO:0016485680.017
chromosome condensationGO:0030261410.017
morphogenesis of a branching structureGO:0001763450.017
developmental programmed cell deathGO:00106231380.017
negative regulation of transcription dna templatedGO:00458922370.017
regulation of antimicrobial peptide productionGO:0002784440.017
negative regulation of gene expressionGO:00106293870.017
positive regulation of macromolecule metabolic processGO:00106044050.017
regulation of i kappab kinase nf kappab signalingGO:004312220.017
Human
reproductive system developmentGO:0061458740.017
carbohydrate derivative biosynthetic processGO:1901137850.017
transforming growth factor beta receptor signaling pathwayGO:0007179160.017
compound eye morphogenesisGO:00017452490.017
response to monosaccharideGO:003428440.017
gastrulationGO:0007369700.017
leg disc morphogenesisGO:0007478800.017
pole plasm mrna localizationGO:0019094490.017
positive regulation of response to biotic stimulusGO:0002833310.017
regulation of ras protein signal transductionGO:0046578930.017
response to hexoseGO:000974630.017
response to lipopolysaccharideGO:003249640.016
camera type eye morphogenesisGO:004859320.016
digestive system developmentGO:00551231490.016
regulation of cell migrationGO:0030334220.016
mesoderm developmentGO:0007498780.016
tripartite regional subdivisionGO:00073511030.016
positive regulation of protein metabolic processGO:00512471280.016
eye morphogenesisGO:00485922600.016
regulation of mapk cascadeGO:0043408920.016
epithelial cell differentiationGO:00308553220.016
positive regulation of cell projection organizationGO:0031346290.016
cellular amino acid metabolic processGO:0006520610.016
purine nucleotide metabolic processGO:00061631460.015
production of molecular mediator of immune responseGO:0002440460.015
amide biosynthetic processGO:0043604420.015
antifungal peptide biosynthetic processGO:000278350.015
cell divisionGO:00513012480.015
renal system developmentGO:0072001720.015
regulation of innate immune responseGO:0045088710.015
response to woundingGO:0009611940.015
epithelial cell migrationGO:00106311480.015
salivary gland morphogenesisGO:00074351450.015
negative regulation of cell differentiationGO:00455961430.015
modification dependent macromolecule catabolic processGO:0043632790.015
outflow tract morphogenesisGO:000315140.015
response to growth factorGO:0070848310.015
regulation of behaviorGO:0050795750.015
anterior posterior axis specification embryoGO:00085951030.015
positive regulation of catalytic activityGO:00430851180.015
lipid metabolic processGO:00066291210.015
nephron tubule developmentGO:007208030.015
positive regulation of immune responseGO:0050778630.014
antifungal peptide productionGO:000278170.014
glycosyl compound metabolic processGO:19016571270.014
positive regulation of i kappab kinase nf kappab signalingGO:004312310.014
Human
single organism intracellular transportGO:19025822070.014
regulation of defense response to bacteriumGO:1900424300.014
positive regulation of protein modification processGO:0031401580.014
developmental growthGO:00485892800.014
positive regulation of erk1 and erk2 cascadeGO:0070374360.014
purine nucleoside triphosphate metabolic processGO:00091441190.014
positive regulation of rna metabolic processGO:00512542710.014
regulation of embryonic developmentGO:0045995680.014
cellular macromolecule catabolic processGO:00442651360.014
columnar cuboidal epithelial cell developmentGO:00020662490.014
signal transduction by phosphorylationGO:00230141070.014
myotube differentiationGO:0014902460.014
regulation of programmed cell deathGO:00430671520.014
hindgut morphogenesisGO:0007442580.014
instar larval developmentGO:0002168550.014
establishment or maintenance of bipolar cell polarityGO:0061245340.014
gastrulation with mouth forming firstGO:0001703360.014
protein targeting to nucleusGO:0044744510.014
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.013
rna localizationGO:00064031150.013
actin filament bundle organizationGO:0061572280.013
wing disc morphogenesisGO:00074723440.013
regulation of phosphate metabolic processGO:00192202100.013
regulation of dendrite developmentGO:0050773370.013
chromatin organizationGO:00063252070.013
regulation of cell cycleGO:00517262910.013
positive regulation of immune effector processGO:0002699280.013
regulation of hydrolase activityGO:0051336970.013
establishment of protein localization to organelleGO:0072594620.013
immune response activating signal transductionGO:000275720.013
positive regulation of gtpase activityGO:0043547430.013
adherens junction organizationGO:0034332270.013
peptidyl amino acid modificationGO:00181931050.012
hemopoiesisGO:0030097460.012
negative regulation of cell proliferationGO:0008285690.012
single organism nuclear importGO:1902593510.012
cilium morphogenesisGO:0060271390.012
signal transduction in response to dna damageGO:004277030.012
regulation of transmembrane receptor protein serine threonine kinase signaling pathwayGO:0090092380.012
circulatory system processGO:0003013370.012
salivary gland developmentGO:00074311620.012
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.012
regulation of compound eye retinal cell programmed cell deathGO:0046669180.012
intracellular protein transportGO:00068861040.012
neuron recognitionGO:00080381010.012
regulation of small gtpase mediated signal transductionGO:0051056930.012
hemocyte differentiationGO:0042386380.012
embryonic axis specificationGO:00005781070.012
regulation of axonogenesisGO:0050770320.012
immune response regulating signaling pathwayGO:000276420.012
protein secretionGO:0009306450.012
establishment of organelle localizationGO:00516561220.012
localization of cellGO:00516742570.012
monocarboxylic acid metabolic processGO:0032787290.012
negative regulation of multicellular organismal processGO:00512411420.011
negative regulation of apoptotic processGO:0043066630.011
negative regulation of phosphatase activityGO:001092330.011
regulation of protein phosphorylationGO:0001932640.011
branching involved in open tracheal system developmentGO:0060446450.011
proteasomal protein catabolic processGO:0010498590.011
regulation of organ morphogenesisGO:2000027780.011
wnt signaling pathwayGO:0016055980.011
positive regulation of defense responseGO:0031349590.011
regulation of humoral immune responseGO:0002920510.011
nucleoside triphosphate metabolic processGO:00091411200.011
positive regulation of production of molecular mediator of immune responseGO:0002702280.011
response to oxygen containing compoundGO:19017002000.011
renal tubule morphogenesisGO:0061333440.010
cellular response to endogenous stimulusGO:0071495800.010
actin polymerization or depolymerizationGO:0008154310.010
regulation of establishment of protein localizationGO:0070201610.010
positive regulation of hydrolase activityGO:0051345780.010
regulation of cellular response to stressGO:0080135890.010
regulation of phosphatase activityGO:001092130.010
protein kinase b signalingGO:004349110.010

pll disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
organ system cancerDOID:005068600.065
cancerDOID:16200.065
disease of cellular proliferationDOID:1456600.065
disease of anatomical entityDOID:700.017