Drosophila melanogaster

23 known processes

hk (Dmel_CG10653)

hook

(Aliases: CG10653,Dmel\CG10653,dHk)

hk biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
locomotory behaviorGO:00076261760.837
membrane fusionGO:0061025420.819
response to starvationGO:0042594970.805
single organism behaviorGO:00447083910.781
establishment of localization in cellGO:00516494020.748
endosome to lysosome transportGO:000833370.681
single organism membrane fusionGO:0044801420.529
synaptic vesicle endocytosisGO:0048488280.470
single organism intracellular transportGO:19025822070.444
organelle fusionGO:0048284460.365
cellular response to extracellular stimulusGO:0031668640.361
regulation of cell differentiationGO:00455953020.314
entrainment of circadian clockGO:0009649160.313
cellular response to starvationGO:0009267610.283
determination of adult lifespanGO:00083401370.256
synaptic vesicle recyclingGO:0036465280.241
regulation of nervous system developmentGO:00519602480.223
organelle membrane fusionGO:0090174160.214
synaptic transmissionGO:00072682880.200
purine ribonucleotide metabolic processGO:00091501450.195
positive regulation of rna biosynthetic processGO:19026802660.194
purine containing compound metabolic processGO:00725211550.190
macroautophagyGO:0016236420.188
autophagic vacuole fusionGO:0000046150.186
synaptic vesicle localizationGO:0097479530.186
adult behaviorGO:00305341370.184
cell deathGO:00082192790.172
establishment of synaptic vesicle localizationGO:0097480500.168
agingGO:00075681430.164
positive regulation of nitrogen compound metabolic processGO:00511733540.151
multi organism reproductive behaviorGO:00447051210.151
ribonucleotide metabolic processGO:00092591450.141
regulation of autophagyGO:0010506620.128
adult locomotory behaviorGO:0008344760.127
endocytosisGO:00068973100.127
regulation of cell cycle processGO:00105641810.123
gliogenesisGO:0042063800.119
enzyme linked receptor protein signaling pathwayGO:00071671790.113
lysosomal transportGO:0007041130.112
cellular response to nutrient levelsGO:0031669620.102
regulation of catabolic processGO:00098941700.101
cell proliferationGO:00082832990.097
neuroblast proliferationGO:0007405740.097
organelle localizationGO:00516401480.096
multicellular organismal agingGO:00102591400.095
regulation of growthGO:00400082330.094
establishment of protein localization to organelleGO:0072594620.092
regulation of mitotic cell cycleGO:00073461900.089
positive regulation of response to stimulusGO:00485843230.084
regulation of catalytic activityGO:00507901850.081
regulation of cell deathGO:00109411730.078
regulation of protein transportGO:0051223570.078
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.077
cytoplasmic transportGO:00164821300.076
regulation of phosphorus metabolic processGO:00511742100.075
endosomal transportGO:0016197440.074
secretionGO:00469031090.073
negative regulation of developmental processGO:00510932010.072
regulation of molecular functionGO:00650092170.071
deathGO:00162652840.071
developmental programmed cell deathGO:00106231380.070
positive regulation of hydrolase activityGO:0051345780.069
regulation of cell developmentGO:00602842150.068
programmed cell deathGO:00125012570.066
cellular catabolic processGO:00442483720.065
negative regulation of developmental growthGO:0048640640.064
notch receptor processingGO:0007220130.064
organophosphate metabolic processGO:00196371950.062
organelle assemblyGO:00709251980.059
regulation of phosphate metabolic processGO:00192202100.058
positive regulation of multicellular organismal processGO:00512401430.057
regulation of cellular catabolic processGO:00313291570.057
positive regulation of rna metabolic processGO:00512542710.057
regulation of transportGO:00510491810.056
regulation of transcription from rna polymerase ii promoterGO:00063573780.055
regulation of organelle organizationGO:00330431960.054
regulation of vesicle mediated transportGO:0060627590.054
secretion by cellGO:00329401010.054
developmental growthGO:00485892800.053
negative regulation of molecular functionGO:0044092510.053
compound eye developmentGO:00487493070.052
anatomical structure homeostasisGO:0060249970.052
nucleobase containing small molecule metabolic processGO:00550861740.051
mitotic cell cycle phase transitionGO:00447721380.051
organonitrogen compound metabolic processGO:19015643180.051
regulation of hydrolase activityGO:0051336970.050
signal releaseGO:0023061490.048
protein targetingGO:0006605640.048
intracellular transportGO:00469072280.046
response to extracellular stimulusGO:00099911160.046
regulation of developmental growthGO:00486381740.045
dorsal ventral pattern formationGO:00099531330.045
homeostatic processGO:00425921990.044
mitotic dna damage checkpointGO:0044773740.044
regulation of localizationGO:00328792750.044
notch signaling pathwayGO:00072191200.043
purine nucleotide metabolic processGO:00061631460.043
regulation of response to stressGO:00801342000.043
phenol containing compound metabolic processGO:0018958570.043
vesicle mediated transportGO:00161923810.042
immune system developmentGO:0002520570.042
regulation of programmed cell deathGO:00430671520.041
positive regulation of nucleic acid templated transcriptionGO:19035082660.041
positive regulation of macromolecule biosynthetic processGO:00105572830.041
regulation of multicellular organismal developmentGO:20000264140.040
negative regulation of response to stimulusGO:00485852580.040
positive regulation of nucleobase containing compound metabolic processGO:00459353320.039
regulation of synaptic growth at neuromuscular junctionGO:0008582890.038
glycosyl compound metabolic processGO:19016571270.037
negative regulation of cell communicationGO:00106482230.034
regulation of cell cycleGO:00517262910.034
central nervous system developmentGO:00074172010.033
eye developmentGO:00016543230.033
purine containing compound biosynthetic processGO:0072522300.033
nucleotide metabolic processGO:00091171610.033
negative regulation of programmed cell deathGO:0043069720.033
positive regulation of developmental processGO:00510941430.033
regulation of cellular response to stressGO:0080135890.033
small molecule metabolic processGO:00442813050.032
regulation of anatomical structure sizeGO:00900661630.032
forebrain developmentGO:003090020.032
stem cell proliferationGO:0072089880.032
learning or memoryGO:00076111410.032
eye pigment granule organizationGO:0008057120.032
positive regulation of cell developmentGO:0010720610.031
cell cycle checkpointGO:0000075950.031
response to nutrient levelsGO:00316671140.031
dopamine biosynthetic processGO:004241630.031
negative regulation of cell differentiationGO:00455961430.031
cellular response to external stimulusGO:0071496660.029
regulation of cellular component biogenesisGO:00440872010.029
establishment of vesicle localizationGO:0051650510.029
negative regulation of nervous system developmentGO:0051961920.029
positive regulation of catabolic processGO:00098961050.029
early endosome to late endosome transportGO:004502230.028
telencephalon developmentGO:002153720.028
protein localizationGO:00081042840.028
negative regulation of multicellular organismal processGO:00512411420.028
oocyte maturationGO:000155630.028
negative regulation of mitotic cell cycle phase transitionGO:19019911030.028
response to decreased oxygen levelsGO:0036293580.027
gtp catabolic processGO:0006184720.027
single organism catabolic processGO:00447122280.027
pigment granule organizationGO:0048753120.027
response to organonitrogen compoundGO:0010243750.026
catabolic processGO:00090564090.026
cellular homeostasisGO:0019725800.025
regulation of purine nucleotide catabolic processGO:0033121480.024
mitotic dna integrity checkpointGO:0044774750.024
response to ethanolGO:0045471590.024
negative regulation of signal transductionGO:00099682060.023
brain developmentGO:00074201200.023
establishment of organelle localizationGO:00516561220.023
purine nucleoside catabolic processGO:00061521120.021
positive regulation of transcription dna templatedGO:00458932660.021
response to oxygen containing compoundGO:19017002000.021
dna double strand break processingGO:000072930.021
regulation of cell cycle phase transitionGO:19019871300.021
regulation of steroid metabolic processGO:001921820.021
dna damage checkpointGO:0000077780.021
positive regulation of molecular functionGO:00440931360.021
response to anestheticGO:007234790.021
centrosome cycleGO:00070981370.020
regulation of nurse cell apoptotic processGO:004547790.020
neurological system processGO:00508773580.020
response to reactive oxygen speciesGO:0000302240.020
carbohydrate derivative metabolic processGO:19011352170.019
positive regulation of intracellular protein transportGO:0090316300.019
cellular response to dna damage stimulusGO:00069742230.019
purine nucleotide catabolic processGO:00061951090.019
regulation of response to external stimulusGO:00321011150.019
guanosine containing compound catabolic processGO:1901069740.019
regulation of nucleotide metabolic processGO:0006140620.019
cell cycle phase transitionGO:00447701400.019
negative regulation of neuron apoptotic processGO:0043524140.019
axonogenesisGO:00074092900.019
protein targeting to nucleusGO:0044744510.019
response to temperature stimulusGO:00092661060.018
exocytosisGO:0006887280.018
regulation of mitotic cell cycle phase transitionGO:19019901300.018
tube developmentGO:00352952440.017
appendage segmentationGO:0035285260.017
taxisGO:00423303040.017
positive regulation of gene expressionGO:00106282900.017
regulation of notch signaling pathwayGO:00085931000.017
protein phosphorylationGO:00064681690.017
membrane organizationGO:00610241120.017
negative regulation of cell deathGO:0060548810.017
neuromuscular processGO:0050905210.017
phosphorylationGO:00163102940.017
purine ribonucleoside metabolic processGO:00461281270.017
regulation of cell cycle g1 s phase transitionGO:1902806230.016
regulation of wnt signaling pathwayGO:0030111680.016
regulation of neuron apoptotic processGO:0043523160.016
regulation of epithelial cell proliferationGO:005067840.016
regulation of cell proliferationGO:00421271630.015
positive regulation of apoptotic processGO:0043065470.015
catecholamine metabolic processGO:0006584100.015
positive regulation of transcription from rna polymerase ii promoterGO:00459442040.015
regulation of cellular localizationGO:00603411360.015
positive regulation of biosynthetic processGO:00098913160.015
nucleoside phosphate metabolic processGO:00067531620.015
positive regulation of signal transductionGO:00099672230.015
regulation of apoptotic processGO:00429811300.015
purine nucleoside metabolic processGO:00422781270.015
head developmentGO:00603221350.015
cellular metal ion homeostasisGO:0006875310.015
regulation of intracellular protein transportGO:0033157460.014
neural precursor cell proliferationGO:0061351750.014
negative regulation of apoptotic processGO:0043066630.014
endomembrane system organizationGO:00102561190.014
regulation of nucleoside metabolic processGO:0009118500.014
ribonucleoside triphosphate metabolic processGO:00091991190.014
organic substance transportGO:00717022570.014
regulation of purine nucleotide metabolic processGO:1900542620.014
positive regulation of macromolecule metabolic processGO:00106044050.014
purine nucleoside triphosphate catabolic processGO:00091461080.014
regulation of protein targetingGO:1903533290.014
regulation of protein metabolic processGO:00512462560.014
axon guidanceGO:00074112330.014
negative regulation of signalingGO:00230572190.013
organonitrogen compound catabolic processGO:19015651280.013
nucleoside triphosphate catabolic processGO:00091431080.013
regulation of necrotic cell deathGO:001093910.013
nucleoside catabolic processGO:00091641120.013
compound eye morphogenesisGO:00017452490.013
purine ribonucleoside catabolic processGO:00461301120.013
intracellular protein transportGO:00068861040.013
negative regulation of biosynthetic processGO:00098902770.013
regulation of intracellular signal transductionGO:19025312360.013
leg disc morphogenesisGO:0007478800.013
entrainment of circadian clock by photoperiodGO:004315390.013
positive regulation of cell deathGO:0010942690.012
positive regulation of protein transportGO:0051222370.012
regulation of synapse assemblyGO:0051963940.012
regulation of nucleotide catabolic processGO:0030811480.012
protein catabolic processGO:00301631010.012
purine containing compound catabolic processGO:00725231120.012
positive regulation of cellular catabolic processGO:0031331950.012
regulation of circadian rhythmGO:0042752490.012
positive regulation of neuron apoptotic processGO:004352510.012
positive regulation of phosphorus metabolic processGO:00105621390.012
growthGO:00400073590.012
regulation of g1 s transition of mitotic cell cycleGO:2000045230.012
larval developmentGO:00021641040.012
negative regulation of rna metabolic processGO:00512532510.012
ribonucleoside catabolic processGO:00424541120.011
lysosome organizationGO:000704040.011
organonitrogen compound biosynthetic processGO:19015661170.011
regulation of synaptic vesicle transportGO:1902803100.011
cell maturationGO:00484691440.011
organic hydroxy compound metabolic processGO:1901615830.011
regulation of cytoskeleton organizationGO:0051493890.011
cell cycle arrestGO:000705040.011
vesicle localizationGO:0051648550.011
response to calcium ionGO:005159210.011
negative regulation of mitotic cell cycleGO:00459301090.011
cellular pigmentationGO:0033059120.011
negative regulation of cell proliferationGO:0008285690.011
camera type eye morphogenesisGO:004859320.011
imaginal disc pattern formationGO:0007447910.011
neuron maturationGO:0042551310.011
cell growthGO:00160491080.010
flight behaviorGO:0007629260.010
positive regulation of cell communicationGO:00106472500.010
wnt signaling pathwayGO:0016055980.010
regulation of synaptic transmissionGO:0050804690.010
purine ribonucleoside monophosphate biosynthetic processGO:000916830.010

hk disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.028
organ system cancerDOID:005068600.028
disease of cellular proliferationDOID:1456600.028
disease of anatomical entityDOID:700.027
nervous system diseaseDOID:86300.017
central nervous system diseaseDOID:33100.017
neurodegenerative diseaseDOID:128900.017
synucleinopathyDOID:005089000.013