IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

RpS28b (Dmel_CG2998)

Ribosomal protein S28b

(Aliases: CG2998,Dmel\CG2998,M(1)8F)

Entrez: 31897
FLYBASE: FBgn0030136
UniProtKB: X2JEM4
UniProtKB: Q9W334

Process Predictions
Disease Predictions

RpS28b biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
mitotic spindle elongation	GO:0000022	81	0.990
spindle elongation	GO:0051231	83	0.980
centrosome organization	GO:0051297	163	0.919
spindle organization	GO:0007051	253	0.893
mitotic spindle organization	GO:0007052	220	0.700
centrosome cycle	GO:0007098	137	0.625
centrosome duplication	GO:0051298	121	0.563
rrna processing	GO:0006364	3	0.367
larval development	GO:0002164	104	0.331	Worm
microtubule organizing center organization	GO:0031023	168	0.298
translation	GO:0006412	69	0.259
embryo development ending in birth or egg hatching	GO:0009792	152	0.258
death	GO:0016265	284	0.216	Worm
cell death	GO:0008219	279	0.214	Worm
rna processing	GO:0006396	147	0.152
establishment of localization in cell	GO:0051649	402	0.149	Yeast
apoptotic process	GO:0006915	159	0.131	Worm
mucosal immune response	GO:0002385	10	0.110
ribonucleoprotein complex biogenesis	GO:0022613	31	0.107	Yeast
antibacterial humoral response	GO:0019731	44	0.103
regulation of multicellular organism growth	GO:0040014	40	0.103
regulation of cell cycle	GO:0051726	291	0.100
programmed cell death	GO:0012501	257	0.100	Worm
molting cycle	GO:0042303	56	0.100	Worm
single organism intracellular transport	GO:1902582	207	0.083	Yeast
immune system process	GO:0002376	347	0.075
establishment of organelle localization	GO:0051656	122	0.074
cytoplasmic transport	GO:0016482	130	0.072	Yeast
nucleocytoplasmic transport	GO:0006913	72	0.072	Yeast
determination of adult lifespan	GO:0008340	137	0.064
innate immune response	GO:0045087	144	0.063
cytoplasmic translation	GO:0002181	0	0.063
mitotic dna integrity checkpoint	GO:0044774	75	0.062
organ or tissue specific immune response	GO:0002251	10	0.059
humoral immune response	GO:0006959	117	0.057
aging	GO:0007568	143	0.056
multicellular organismal aging	GO:0010259	140	0.053
ncrna metabolic process	GO:0034660	43	0.053
ncrna processing	GO:0034470	30	0.051
regulation of molecular function	GO:0065009	217	0.050
rna localization	GO:0006403	115	0.050	Yeast
organelle assembly	GO:0070925	198	0.048
protein modification process	GO:0036211	438	0.047
nuclear transport	GO:0051169	72	0.047	Yeast
response to other organism	GO:0051707	293	0.046
endocytosis	GO:0006897	310	0.046
response to external biotic stimulus	GO:0043207	293	0.046
regulation of phosphate metabolic process	GO:0019220	210	0.044
positive regulation of response to stimulus	GO:0048584	323	0.043
regulation of cell cycle process	GO:0010564	181	0.043
cellular protein modification process	GO:0006464	438	0.042
immune response	GO:0006955	246	0.041
nuclear export	GO:0051168	24	0.040	Yeast
response to abiotic stimulus	GO:0009628	341	0.040
response to heat	GO:0009408	63	0.037
positive regulation of biosynthetic process	GO:0009891	316	0.035
response to biotic stimulus	GO:0009607	294	0.033
nucleobase containing compound transport	GO:0015931	56	0.033	Yeast
cellular macromolecular complex assembly	GO:0034622	153	0.032
positive regulation of macromolecule metabolic process	GO:0010604	405	0.032	Yeast
negative regulation of cell cycle	GO:0045786	116	0.032
response to oxygen containing compound	GO:1901700	200	0.032
positive regulation of multicellular organism growth	GO:0040018	21	0.032
vesicle mediated transport	GO:0016192	381	0.031
response to temperature stimulus	GO:0009266	106	0.030
intracellular signal transduction	GO:0035556	300	0.030
developmental growth	GO:0048589	280	0.030
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.029
organic substance transport	GO:0071702	257	0.029	Yeast
localization of cell	GO:0051674	257	0.029
defense response	GO:0006952	300	0.029
positive regulation of signaling	GO:0023056	243	0.028
transcription from rna polymerase ii promoter	GO:0006366	368	0.028
catabolic process	GO:0009056	409	0.028	Yeast
body morphogenesis	GO:0010171	2	0.028
cellular response to dna damage stimulus	GO:0006974	223	0.028
defense response to other organism	GO:0098542	225	0.028
negative regulation of cellular metabolic process	GO:0031324	382	0.028
head development	GO:0060322	135	0.027
cell motility	GO:0048870	251	0.027
positive regulation of cell communication	GO:0010647	250	0.027
dna damage checkpoint	GO:0000077	78	0.026
regulation of catalytic activity	GO:0050790	185	0.026
phagocytosis	GO:0006909	215	0.026
mitotic cell cycle phase transition	GO:0044772	138	0.025
intracellular transport	GO:0046907	228	0.025	Yeast
positive regulation of macromolecule biosynthetic process	GO:0010557	283	0.025
defense response to bacterium	GO:0042742	178	0.024
salivary gland morphogenesis	GO:0007435	145	0.024
regulation of cellular protein metabolic process	GO:0032268	243	0.024
cell cycle checkpoint	GO:0000075	95	0.024
positive regulation of signal transduction	GO:0009967	223	0.024
regulation of protein modification process	GO:0031399	112	0.024
regulation of protein metabolic process	GO:0051246	256	0.023
macromolecular complex assembly	GO:0065003	256	0.023
positive regulation of cysteine type endopeptidase activity	GO:2001056	24	0.023
homeostatic process	GO:0042592	199	0.022
mitotic cell cycle checkpoint	GO:0007093	88	0.022
reproductive system development	GO:0061458	74	0.022
positive regulation of catalytic activity	GO:0043085	118	0.021
negative regulation of gene expression	GO:0010629	387	0.021
protein ubiquitination	GO:0016567	70	0.021
cell proliferation	GO:0008283	299	0.021
defense response to gram positive bacterium	GO:0050830	41	0.021
cell cycle phase transition	GO:0044770	140	0.021
protein phosphorylation	GO:0006468	169	0.021
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.021
positive regulation of phosphorylation	GO:0042327	87	0.020
salivary gland cell autophagic cell death	GO:0035071	83	0.020
regulation of mitotic cell cycle	GO:0007346	190	0.020
positive regulation of molecular function	GO:0044093	136	0.020
organic substance catabolic process	GO:1901575	308	0.019	Yeast
exocrine system development	GO:0035272	162	0.019
development of primary sexual characteristics	GO:0045137	50	0.018
negative regulation of biosynthetic process	GO:0009890	277	0.018
central nervous system development	GO:0007417	201	0.018
nitrogen compound transport	GO:0071705	85	0.018	Yeast
protein transport	GO:0015031	155	0.018
positive regulation of developmental growth	GO:0048639	62	0.018
posttranscriptional regulation of gene expression	GO:0010608	145	0.018
regulation of phosphorus metabolic process	GO:0051174	210	0.018
dna metabolic process	GO:0006259	227	0.018
positive regulation of gene expression	GO:0010628	290	0.017
positive regulation of intracellular signal transduction	GO:1902533	116	0.017
protein targeting	GO:0006605	64	0.017
activation of cysteine type endopeptidase activity	GO:0097202	17	0.017
regulation of cell death	GO:0010941	173	0.017
phosphorylation	GO:0016310	294	0.017
protein localization	GO:0008104	284	0.017
nucleosome organization	GO:0034728	59	0.017
activation of cysteine type endopeptidase activity involved in apoptotic process	GO:0006919	16	0.016
positive regulation of growth	GO:0045927	75	0.016
regulation of phosphorylation	GO:0042325	147	0.016
gland morphogenesis	GO:0022612	145	0.016
response to bacterium	GO:0009617	198	0.016
regulation of growth	GO:0040008	233	0.016
cell migration	GO:0016477	238	0.016
response to organic substance	GO:0010033	284	0.016
regulation of apoptotic process	GO:0042981	130	0.016
single organism catabolic process	GO:0044712	228	0.015
regulation of developmental growth	GO:0048638	174	0.015
mitotic dna damage checkpoint	GO:0044773	74	0.015
positive regulation of cellular protein metabolic process	GO:0032270	118	0.015
sex differentiation	GO:0007548	81	0.015
protein modification by small protein conjugation or removal	GO:0070647	106	0.014
dna integrity checkpoint	GO:0031570	81	0.014
establishment of planar polarity	GO:0001736	87	0.014
negative regulation of cell cycle phase transition	GO:1901988	103	0.014
regulation of protein kinase activity	GO:0045859	51	0.014
positive regulation of developmental process	GO:0051094	143	0.014
posttranscriptional gene silencing	GO:0016441	46	0.014
positive regulation of cell death	GO:0010942	69	0.013
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.013
substrate adhesion dependent cell spreading	GO:0034446	2	0.013
regulation of intracellular signal transduction	GO:1902531	236	0.013
salivary gland development	GO:0007431	162	0.013
antimicrobial humoral response	GO:0019730	99	0.013
organelle localization	GO:0051640	148	0.013
organonitrogen compound metabolic process	GO:1901564	318	0.013
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.013
meiotic cell cycle process	GO:1903046	132	0.012
growth	GO:0040007	359	0.012
spermatogenesis	GO:0007283	200	0.012
regulation of programmed cell death	GO:0043067	152	0.012
cellular response to organic substance	GO:0071310	132	0.012
ameboidal type cell migration	GO:0001667	151	0.012
autophagic cell death	GO:0048102	83	0.012
regulation of cell cycle phase transition	GO:1901987	130	0.012
dna repair	GO:0006281	54	0.012
positive regulation of peptidase activity	GO:0010952	29	0.012
positive regulation of apoptotic process	GO:0043065	47	0.012
regulation of cell proliferation	GO:0042127	163	0.012
negative regulation of mitotic cell cycle	GO:0045930	109	0.012
regulation of innate immune response	GO:0045088	71	0.012
positive regulation of cellular biosynthetic process	GO:0031328	316	0.012
response to wounding	GO:0009611	94	0.011
gene silencing	GO:0016458	138	0.011
regulation of cellular component size	GO:0032535	98	0.011
male gamete generation	GO:0048232	201	0.011
chemical homeostasis	GO:0048878	92	0.011
neuron recognition	GO:0008038	101	0.011
histolysis	GO:0007559	102	0.011
axis specification	GO:0009798	167	0.011
establishment of protein localization	GO:0045184	163	0.011
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.011
protein catabolic process	GO:0030163	101	0.011
positive regulation of programmed cell death	GO:0043068	62	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011	Yeast
developmental programmed cell death	GO:0010623	138	0.011
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.010
regulation of response to external stimulus	GO:0032101	115	0.010
positive regulation of hydrolase activity	GO:0051345	78	0.010
cation transport	GO:0006812	110	0.010
eye development	GO:0001654	323	0.010
rna transport	GO:0050658	46	0.010	Yeast
cellular response to chemical stimulus	GO:0070887	199	0.010
proteolysis	GO:0006508	192	0.010
regulation of response to stress	GO:0080134	200	0.010

RpS28b disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.071
immune system disease	DOID:2914	0.024
bone marrow disease	DOID:4961	0.024
hematopoietic system disease	DOID:74	0.024
anemia	DOID:2355	0.024
aplastic anemia	DOID:12449	0.024

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