Drosophila melanogaster

10 known processes

Hsp23 (Dmel_CG4463)

Heat shock protein 23

(Aliases: CG4463,23,hsp23,Hsp-23,HSP23/IAP,DmHsp23,HSP23,hsp23/22,hsp 23,hsp 23K,Dmel\CG4463,small hsp locus 67B,hsp 22K)

Hsp23 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
appendage developmentGO:00487364010.655
Fly
negative regulation of reactive oxygen species metabolic processGO:200037810.622
Rat
imaginal disc derived appendage developmentGO:00487373990.548
Fly
imaginal disc derived appendage morphogenesisGO:00351143950.546
Fly
wing disc morphogenesisGO:00074723440.539
Fly
response to temperature stimulusGO:00092661060.459
response to heatGO:0009408630.370
Rat Fly
post embryonic appendage morphogenesisGO:00351203850.327
Fly
response to hydrogen peroxideGO:0042542110.326
Mouse Rat
appendage morphogenesisGO:00351073970.317
Fly
apoptotic process involved in morphogenesisGO:006056130.294
Mouse
imaginal disc derived wing morphogenesisGO:00074763370.253
Fly
glutathione metabolic processGO:0006749370.209
defense response to bacteriumGO:00427421780.182
Fly
growthGO:00400073590.179
Rat
defense responseGO:00069523000.168
Fly
response to fungusGO:0009620500.161
Fly
epithelial cell differentiationGO:00308553220.153
response to endogenous stimulusGO:00097191190.146
Rat
response to bacteriumGO:00096171980.119
Fly
cellular response to ionizing radiationGO:0071479150.119
heat shock mediated polytene chromosome puffingGO:003508070.115
response to other organismGO:00517072930.112
Fly
cellular amide metabolic processGO:0043603800.108
negative regulation of cellular metabolic processGO:00313243820.107
Mouse Rat
defense response to other organismGO:00985422250.106
Fly
response to extracellular stimulusGO:00099911160.102
Fly
regulation of growthGO:00400082330.097
Rat
cellular modified amino acid metabolic processGO:0006575450.089
response to coldGO:0009409130.088
negative regulation of biosynthetic processGO:00098902770.086
response to abiotic stimulusGO:00096283410.083
regulation of protein metabolic processGO:00512462560.079
Mouse
response to reactive oxygen speciesGO:0000302240.076
Mouse Rat
macromolecular complex assemblyGO:00650032560.075
Human Mouse
behavioral response to starvationGO:004259560.075
Fly
cold acclimationGO:000963180.074
chemotaxisGO:00069352490.071
regulation of i kappab kinase nf kappab signalingGO:004312220.069
Mouse
cellular protein complex assemblyGO:0043623710.067
Mouse
intracellular signal transductionGO:00355563000.067
Mouse Rat
peptide metabolic processGO:0006518800.067
establishment of localization in cellGO:00516494020.065
Human
taxisGO:00423303040.065
actin cytoskeleton organizationGO:00300362060.063
camera type eye morphogenesisGO:004859320.063
transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071691160.062
camera type eye developmentGO:004301040.061
Mouse
sensory perceptionGO:00076001960.061
Human
cellular response to gamma radiationGO:0071480100.059
stress activated mapk cascadeGO:0051403520.058
Rat
positive regulation of macromolecule metabolic processGO:00106044050.057
Mouse
regulation of response to external stimulusGO:00321011150.056
intracellular transportGO:00469072280.056
Human
response to nutrient levelsGO:00316671140.056
Fly
negative regulation of response to stimulusGO:00485852580.055
Mouse
negative regulation of rna biosynthetic processGO:19026792400.055
transcription from rna polymerase ii promoterGO:00063663680.055
regulation of cell deathGO:00109411730.055
Human Mouse Rat
negative regulation of endopeptidase activityGO:0010951110.054
Mouse
detection of abiotic stimulusGO:0009582660.054
positive regulation of cell motilityGO:200014730.054
multicellular organismal agingGO:00102591400.054
Fly
negative regulation of nitrogen compound metabolic processGO:00511722650.054
deathGO:00162652840.054
Human Mouse Rat
regulation of cellular protein metabolic processGO:00322682430.053
Mouse
phosphorylationGO:00163102940.053
Mouse Rat
enzyme linked receptor protein signaling pathwayGO:00071671790.052
response to external biotic stimulusGO:00432072930.051
Fly
response to radiationGO:00093141550.051
regulation of cell growthGO:0001558430.051
Rat
regulation of cysteine type endopeptidase activityGO:2000116270.050
Mouse
regulation of programmed cell deathGO:00430671520.049
Human Mouse Rat
sulfur compound metabolic processGO:0006790590.048
epithelial cell developmentGO:00020642740.047
regulation of intracellular signal transductionGO:19025312360.047
Mouse
cell growthGO:00160491080.047
Rat
negative regulation of cellular response to oxidative stressGO:190040810.046
Mouse
response to biotic stimulusGO:00096072940.045
Fly
actin filament based processGO:00300292200.045
negative regulation of cell deathGO:0060548810.045
Human Mouse Rat
agingGO:00075681430.043
Rat Fly
negative regulation of macromolecule biosynthetic processGO:00105582700.043
sensory perception of light stimulusGO:0050953120.043
Human
regulation of behaviorGO:0050795750.043
translationGO:0006412690.042
apoptotic processGO:00069151590.042
Human Mouse Rat
cellular response to radiationGO:0071478520.041
programmed cell deathGO:00125012570.041
Human Mouse Rat
negative regulation of cellular biosynthetic processGO:00313272770.041
regulation of response to stressGO:00801342000.041
Mouse
positive regulation of response to external stimulusGO:0032103440.041
detection of stimulusGO:00516061560.041
regulation of cysteine type endopeptidase activity involved in apoptotic processGO:0043281250.041
Mouse
defense response to fungusGO:0050832480.040
Fly
regulation of response to oxidative stressGO:190288240.040
Mouse
regulation of apoptotic processGO:00429811300.040
Human Mouse Rat
negative regulation of cell communicationGO:00106482230.040
Mouse
regulation of multicellular organismal developmentGO:20000264140.039
eye morphogenesisGO:00485922600.039
response to ionizing radiationGO:0010212320.038
cellular protein modification processGO:00064644380.038
Mouse
negative regulation of peptidase activityGO:0010466110.037
Mouse
positive regulation of cell migrationGO:003033520.037
cellular response to heatGO:0034605240.037
rna localizationGO:00064031150.037
detection of external stimulusGO:0009581660.037
muscle system processGO:0003012210.036
Rat
protein phosphorylationGO:00064681690.036
Mouse
signal transduction by phosphorylationGO:00230141070.035
Rat
protein complex assemblyGO:00064612000.035
Human Mouse
regulation of intracellular transportGO:0032386640.034
Human
oxoacid metabolic processGO:00434361030.033
negative regulation of apoptotic processGO:0043066630.033
Human Mouse Rat
response to organic cyclic compoundGO:0014070890.033
Rat
dna damage checkpointGO:0000077780.033
tissue homeostasisGO:0001894360.032
response to organic substanceGO:00100332840.032
Rat
cellular amino acid metabolic processGO:0006520610.032
regulation of translationGO:0006417560.032
regulation of phosphorus metabolic processGO:00511742100.032
Mouse
negative regulation of growthGO:0045926840.032
Rat
response to oxygen containing compoundGO:19017002000.031
Mouse Rat
regulation of cellular response to stressGO:0080135890.031
Mouse
regulation of cell cycle phase transitionGO:19019871300.031
reactive oxygen species metabolic processGO:0072593220.031
Rat
response to hypoxiaGO:0001666530.030
protein complex biogenesisGO:00702712010.030
Human Mouse
muscle organ developmentGO:00075171270.030
Mouse
microtubule polymerization or depolymerizationGO:0031109390.030
Rat
negative regulation of gene expressionGO:00106293870.030
Mouse
negative regulation of response to oxidative stressGO:190288310.029
Mouse
regulation of system processGO:0044057360.029
Rat
muscle structure developmentGO:00610612240.029
Mouse
regulation of transportGO:00510491810.029
Human
response to oxidative stressGO:0006979860.029
Mouse Rat Fly
negative regulation of transcription dna templatedGO:00458922370.029
columnar cuboidal epithelial cell developmentGO:00020662490.028
stress activated protein kinase signaling cascadeGO:0031098550.028
Rat
regulation of cell differentiationGO:00455953020.028
biological adhesionGO:00226101380.028
response to alcoholGO:0097305950.027
Rat
autophagyGO:00069141080.027
cell cycle checkpointGO:0000075950.027
response to light stimulusGO:00094161240.027
spermatogenesisGO:00072832000.027
muscle contractionGO:0006936130.027
Rat
male courtship behaviorGO:0008049630.026
rna processingGO:00063961470.026
regulation of molecular functionGO:00650092170.026
Mouse
actin filament organizationGO:00070151260.026
negative regulation of signal transductionGO:00099682060.025
Mouse
regulation of anatomical structure morphogenesisGO:00226032420.025
visual perceptionGO:000760190.025
Human
response to nitrogen compoundGO:1901698900.025
anatomical structure homeostasisGO:0060249970.025
response to starvationGO:0042594970.024
Fly
mitotic dna integrity checkpointGO:0044774750.024
organonitrogen compound metabolic processGO:19015643180.024
homeostatic processGO:00425921990.023
multicellular organismal homeostasisGO:0048871410.023
cellular macromolecular complex assemblyGO:00346221530.023
Mouse
determination of adult lifespanGO:00083401370.023
Fly
negative regulation of programmed cell deathGO:0043069720.023
Human Mouse Rat
sensory organ morphogenesisGO:00905962600.023
organic acid metabolic processGO:00060821030.023
regulation of cell cycle processGO:00105641810.023
posttranscriptional regulation of gene expressionGO:00106081450.022
g2 dna damage checkpointGO:0031572690.022
cell cycle phase transitionGO:00447701400.022
regulation of chemotaxisGO:0050920120.022
positive regulation of biosynthetic processGO:00098913160.022
Mouse
response to woundingGO:0009611940.022
mitotic g2 dna damage checkpointGO:0007095690.022
jak stat cascadeGO:0007259490.021
mitotic g2 m transition checkpointGO:0044818700.021
cellular response to organic substanceGO:00713101320.021
negative regulation of protein metabolic processGO:0051248850.021
Mouse
neurological system processGO:00508773580.020
Human
regulation of reactive oxygen species metabolic processGO:200037780.020
Rat
regulation of epithelial cell migrationGO:0010632120.020
regulation of localizationGO:00328792750.020
Human
cellular response to oxidative stressGO:0034599280.020
Mouse
polytene chromosome puffingGO:003507970.019
negative regulation of transferase activityGO:0051348180.019
Mouse
negative regulation of cellular macromolecule biosynthetic processGO:20001132670.019
ameboidal type cell migrationGO:00016671510.019
regulation of defense responseGO:00313471020.019
amine metabolic processGO:0009308120.019
response to gamma radiationGO:0010332170.019
regionalizationGO:00030024160.019
mitotic nuclear divisionGO:00070672130.019
mitotic cell cycle checkpointGO:0007093880.018
cell maturationGO:00484691440.018
positive regulation of cellular protein metabolic processGO:00322701180.018
negative regulation of cell cycleGO:00457861160.018
positive regulation of signal transductionGO:00099672230.018
columnar cuboidal epithelial cell differentiationGO:00020652560.018
cellular response to abiotic stimulusGO:0071214580.018
single organism behaviorGO:00447083910.018
negative regulation of intracellular signal transductionGO:1902532570.018
Mouse
cell adhesionGO:00071551360.018
cellular response to chemical stimulusGO:00708871990.018
Mouse
regulation of transferase activityGO:0051338580.017
Mouse
regulation of proteolysisGO:0030162870.017
Mouse
regulation of cellular ketone metabolic processGO:001056530.017
small molecule metabolic processGO:00442813050.017
synapse organizationGO:00508081960.017
negative regulation of kinase activityGO:0033673160.017
Mouse
pole plasm rna localizationGO:0007316520.017
dna integrity checkpointGO:0031570810.017
spermatid developmentGO:0007286980.017
positive regulation of developmental processGO:00510941430.017
positive regulation of signalingGO:00230562430.017
negative regulation of nucleic acid templated transcriptionGO:19035072400.016
single organismal cell cell adhesionGO:0016337450.016
cellular amine metabolic processGO:0044106120.016
oocyte axis specificationGO:00073091080.016
negative regulation of cell cycle phase transitionGO:19019881030.016
negative regulation of signalingGO:00230572190.016
Mouse
developmental programmed cell deathGO:00106231380.016
Mouse
carboxylic acid metabolic processGO:0019752920.016
regulation of mitotic cell cycle phase transitionGO:19019901300.016
mitotic dna damage checkpointGO:0044773740.016
somatic muscle developmentGO:0007525660.016
histolysisGO:00075591020.016
positive regulation of response to stimulusGO:00485843230.016
regulation of hydrolase activityGO:0051336970.016
Mouse
negative regulation of rna metabolic processGO:00512532510.016
body morphogenesisGO:001017120.016
positive regulation of multi organism processGO:0043902400.016
regulation of phosphate metabolic processGO:00192202100.016
Mouse
embryonic morphogenesisGO:00485982060.016
mesenchymal cell differentiationGO:004876210.016
single organism cell adhesionGO:0098602470.016
regulation of catalytic activityGO:00507901850.015
Mouse
larval developmentGO:00021641040.015
open tracheal system developmentGO:00074242040.015
regulation of protein modification processGO:00313991120.015
Mouse
mitotic cell cycle phase transitionGO:00447721380.015
positive regulation of cellular biosynthetic processGO:00313283160.015
Mouse
forebrain developmentGO:003090020.015
dorsal ventral pattern formationGO:00099531330.014
negative regulation of phosphate metabolic processGO:0045936450.014
Mouse
negative regulation of cell differentiationGO:00455961430.014
negative regulation of mitotic cell cycle phase transitionGO:19019911030.014
embryonic pattern specificationGO:00098801740.014
response to lipopolysaccharideGO:003249640.014
intracellular mrna localization involved in pattern specification processGO:0060810560.014
cell deathGO:00082192790.014
Human Mouse Rat
positive regulation of multicellular organismal processGO:00512401430.014
Mouse
response to organonitrogen compoundGO:0010243750.014
proteolysisGO:00065081920.014
Mouse
response to methotrexateGO:0031427110.014
regulation of mitotic cell cycleGO:00073461900.014
axis specificationGO:00097981670.014
salivary gland cell autophagic cell deathGO:0035071830.013
regulation of transcription from rna polymerase ii promoterGO:00063573780.013
spinal cord developmentGO:002151010.013
positive regulation of apoptotic signaling pathwayGO:200123540.013
wound healingGO:0042060750.013
positive regulation of chemotaxisGO:005092120.013
oocyte differentiationGO:00099941450.013
response to virusGO:0009615280.013
regulation of cell cycleGO:00517262910.013
detection of light stimulusGO:0009583580.013
positive regulation of cellular amine metabolic processGO:003324000.013
regulation of cellular amine metabolic processGO:003323830.013
salivary gland histolysisGO:0035070880.013
positive regulation of phosphorus metabolic processGO:00105621390.013
mapk cascadeGO:00001651070.013
Rat
limb developmentGO:006017310.012
cytoplasmic transportGO:00164821300.012
regulation of multi organism processGO:00439001310.012
chromosome organizationGO:00512763600.012
regulation of autophagyGO:0010506620.012
protein processingGO:0016485680.012
Mouse
negative regulation of mitotic cell cycleGO:00459301090.012
response to uvGO:0009411240.012
leg disc morphogenesisGO:0007478800.012
cellular response to extracellular stimulusGO:0031668640.012
regulation of cellular component biogenesisGO:00440872010.012
organic substance transportGO:00717022570.012
negative regulation of defense responseGO:0031348350.012
regulation of cell developmentGO:00602842150.012
compound eye developmentGO:00487493070.012
phosphatidylethanolamine metabolic processGO:004633710.012
tissue deathGO:00162711020.012
mushroom body developmentGO:0016319700.012
regulation of phosphorylationGO:00423251470.012
Mouse
pigment biosynthetic processGO:0046148360.012
limb morphogenesisGO:003510810.012
cellular response to nitrogen compoundGO:1901699510.012
response to organophosphorusGO:004668320.012
developmental maturationGO:00217001720.011
cellular biogenic amine catabolic processGO:004240210.011
positive regulation of cell deathGO:0010942690.011
imaginal disc derived leg morphogenesisGO:0007480800.011
epithelium migrationGO:00901321480.011
macromolecule catabolic processGO:00090571610.011
negative regulation of cysteine type endopeptidase activity involved in apoptotic processGO:004315420.011
Mouse
memoryGO:0007613940.011
lipopolysaccharide mediated signaling pathwayGO:003166310.011
cell cycle arrestGO:000705040.011
embryonic organ developmentGO:0048568500.011
positive regulation of macromolecule biosynthetic processGO:00105572830.011
Mouse
positive regulation of cell communicationGO:00106472500.011
gtp metabolic processGO:0046039720.011
positive regulation of melanization defense responseGO:003500810.011
negative regulation of molecular functionGO:0044092510.011
Mouse
innate immune responseGO:00450871440.011
apoptotic signaling pathwayGO:0097190270.011
Mouse
catabolic processGO:00090564090.011
pole plasm oskar mrna localizationGO:0045451460.011
positive regulation of rna biosynthetic processGO:19026802660.011
response to growth factorGO:0070848310.011
regulation of body fluid levelsGO:0050878140.010
cellular response to oxygen containing compoundGO:1901701790.010
response to endoplasmic reticulum stressGO:0034976280.010
phagocytosisGO:00069092150.010
regulation of defense response to bacteriumGO:1900424300.010
cellular response to biotic stimulusGO:007121640.010
adult behaviorGO:00305341370.010
negative regulation of developmental processGO:00510932010.010
positive regulation of phosphate metabolic processGO:00459371390.010
positive regulation of cellular amino acid metabolic processGO:004576400.010
regulation of small gtpase mediated signal transductionGO:0051056930.010
salivary gland morphogenesisGO:00074351450.010

Hsp23 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
neuropathyDOID:87000.529
Human
charcot marie tooth diseaseDOID:1059500.529
Human
nervous system diseaseDOID:86300.529
Human
disease of anatomical entityDOID:700.529
Human
charcot marie tooth disease type 2DOID:005053900.529
Human
neuromuscular diseaseDOID:44000.529
Human
central nervous system diseaseDOID:33100.358
Human
motor neuron diseaseDOID:23100.358
Human
neurodegenerative diseaseDOID:128900.358
Human
musculoskeletal system diseaseDOID:1700.103
cardiovascular system diseaseDOID:128700.103
muscle tissue diseaseDOID:6600.098
muscular diseaseDOID:008000000.098
cardiomyopathyDOID:005070000.067
heart diseaseDOID:11400.067
intrinsic cardiomyopathyDOID:006003600.067
myopathyDOID:42300.067
eye diseaseDOID:561400.066
eye and adnexa diseaseDOID:149200.066
sensory system diseaseDOID:005015500.066
dilated cardiomyopathyDOID:1293000.025
disease of cellular proliferationDOID:1456600.012
cancerDOID:16200.012