| positive regulation of rna biosynthetic process | GO:1902680 | 266 | 0.834 | |
| positive regulation of nucleic acid templated transcription | GO:1903508 | 266 | 0.733 | |
| negative regulation of rna biosynthetic process | GO:1902679 | 240 | 0.672 | |
| positive regulation of macromolecule metabolic process | GO:0010604 | 405 | 0.601 | |
| positive regulation of cellular biosynthetic process | GO:0031328 | 316 | 0.500 | |
| positive regulation of rna metabolic process | GO:0051254 | 271 | 0.492 | |
| chromosome organization | GO:0051276 | 360 | 0.477 | |
| meiotic cell cycle process | GO:1903046 | 132 | 0.470 | |
| gene silencing | GO:0016458 | 138 | 0.469 | |
| positive regulation of transcription from rna polymerase ii promoter | GO:0045944 | 204 | 0.462 | |
| positive regulation of transcription dna templated | GO:0045893 | 266 | 0.461 | |
| rna polymerase ii transcriptional preinitiation complex assembly | GO:0051123 | 20 | 0.453 | |
| regulation of transcription from rna polymerase ii promoter | GO:0006357 | 378 | 0.433 | |
| dendrite morphogenesis | GO:0048813 | 199 | 0.413 | |
| positive regulation of macromolecule biosynthetic process | GO:0010557 | 283 | 0.404 | |
| nuclear division | GO:0000280 | 332 | 0.387 | |
| tissue morphogenesis | GO:0048729 | 297 | 0.326 | |
| positive regulation of gene expression | GO:0010628 | 290 | 0.306 | |
| male gamete generation | GO:0048232 | 201 | 0.304 | Rat |
| chromatin organization | GO:0006325 | 207 | 0.295 | |
| regulation of cell cycle process | GO:0010564 | 181 | 0.295 | |
| chromatin modification | GO:0016568 | 147 | 0.291 | |
| cell division | GO:0051301 | 248 | 0.271 | |
| response to external biotic stimulus | GO:0043207 | 293 | 0.257 | |
| morphogenesis of an epithelium | GO:0002009 | 276 | 0.242 | |
| transcription from rna polymerase ii promoter | GO:0006366 | 368 | 0.229 | |
| dna templated transcriptional preinitiation complex assembly | GO:0070897 | 20 | 0.228 | |
| developmental growth | GO:0048589 | 280 | 0.215 | |
| regulation of cell cycle | GO:0051726 | 291 | 0.200 | |
| dna templated transcription initiation | GO:0006352 | 25 | 0.199 | |
| positive regulation of nucleobase containing compound metabolic process | GO:0045935 | 332 | 0.196 | |
| meiosis i | GO:0007127 | 59 | 0.196 | |
| negative regulation of nucleic acid templated transcription | GO:1903507 | 240 | 0.194 | |
| negative regulation of cellular metabolic process | GO:0031324 | 382 | 0.182 | |
| tube development | GO:0035295 | 244 | 0.170 | |
| positive regulation of biosynthetic process | GO:0009891 | 316 | 0.166 | |
| meiotic nuclear division | GO:0007126 | 151 | 0.163 | |
| negative regulation of gene expression | GO:0010629 | 387 | 0.153 | |
| organic substance transport | GO:0071702 | 257 | 0.148 | |
| chromatin silencing | GO:0006342 | 76 | 0.146 | |
| negative regulation of transcription dna templated | GO:0045892 | 237 | 0.146 | |
| covalent chromatin modification | GO:0016569 | 106 | 0.141 | |
| positive regulation of nitrogen compound metabolic process | GO:0051173 | 354 | 0.130 | |
| muscle structure development | GO:0061061 | 224 | 0.128 | |
| negative regulation of biosynthetic process | GO:0009890 | 277 | 0.126 | |
| regulation of multicellular organismal development | GO:2000026 | 414 | 0.119 | |
| dendrite development | GO:0016358 | 204 | 0.117 | |
| negative regulation of rna metabolic process | GO:0051253 | 251 | 0.116 | |
| negative regulation of cellular macromolecule biosynthetic process | GO:2000113 | 267 | 0.112 | |
| protein dna complex subunit organization | GO:0071824 | 86 | 0.109 | |
| immune system process | GO:0002376 | 347 | 0.104 | |
| growth | GO:0040007 | 359 | 0.098 | |
| regulation of mitotic cell cycle | GO:0007346 | 190 | 0.097 | |
| regulation of gene expression epigenetic | GO:0040029 | 128 | 0.094 | |
| regulation of catabolic process | GO:0009894 | 170 | 0.092 | |
| meiotic cell cycle | GO:0051321 | 171 | 0.083 | |
| negative regulation of gene expression epigenetic | GO:0045814 | 77 | 0.083 | |
| neuron projection guidance | GO:0097485 | 241 | 0.080 | |
| imaginal disc derived appendage morphogenesis | GO:0035114 | 395 | 0.075 | |
| protein dna complex assembly | GO:0065004 | 63 | 0.074 | |
| negative regulation of nitrogen compound metabolic process | GO:0051172 | 265 | 0.073 | |
| developmental programmed cell death | GO:0010623 | 138 | 0.072 | |
| gland morphogenesis | GO:0022612 | 145 | 0.071 | |
| regulation of mitotic cell cycle phase transition | GO:1901990 | 130 | 0.071 | |
| positive regulation of response to stimulus | GO:0048584 | 323 | 0.067 | |
| negative regulation of cell communication | GO:0010648 | 223 | 0.066 | |
| protein localization | GO:0008104 | 284 | 0.063 | |
| histone modification | GO:0016570 | 106 | 0.063 | |
| transcription initiation from rna polymerase ii promoter | GO:0006367 | 25 | 0.063 | |
| cellular protein localization | GO:0034613 | 160 | 0.063 | |
| regulation of cellular response to stress | GO:0080135 | 89 | 0.061 | |
| regulation of gene silencing | GO:0060968 | 63 | 0.060 | |
| regulation of cell death | GO:0010941 | 173 | 0.059 | |
| cell migration | GO:0016477 | 238 | 0.059 | |
| appendage morphogenesis | GO:0035107 | 397 | 0.058 | |
| regulation of growth | GO:0040008 | 233 | 0.058 | |
| regionalization | GO:0003002 | 416 | 0.056 | |
| organonitrogen compound metabolic process | GO:1901564 | 318 | 0.055 | |
| regulation of cell cycle phase transition | GO:1901987 | 130 | 0.055 | |
| ribonucleoside metabolic process | GO:0009119 | 127 | 0.055 | |
| epithelial cell differentiation | GO:0030855 | 322 | 0.053 | |
| epithelial tube morphogenesis | GO:0060562 | 88 | 0.052 | |
| ovarian follicle cell migration | GO:0007297 | 121 | 0.051 | |
| appendage development | GO:0048736 | 401 | 0.050 | |
| negative regulation of macromolecule biosynthetic process | GO:0010558 | 270 | 0.050 | |
| response to other organism | GO:0051707 | 293 | 0.050 | |
| taxis | GO:0042330 | 304 | 0.049 | |
| response to biotic stimulus | GO:0009607 | 294 | 0.049 | |
| mitotic nuclear division | GO:0007067 | 213 | 0.049 | |
| positive regulation of cellular protein metabolic process | GO:0032270 | 118 | 0.049 | |
| establishment of protein localization | GO:0045184 | 163 | 0.047 | |
| positive regulation of developmental growth | GO:0048639 | 62 | 0.047 | |
| regulation of response to stress | GO:0080134 | 200 | 0.045 | |
| imaginal disc derived appendage development | GO:0048737 | 399 | 0.045 | |
| death | GO:0016265 | 284 | 0.045 | |
| axon development | GO:0061564 | 297 | 0.044 | |
| internal protein amino acid acetylation | GO:0006475 | 38 | 0.044 | |
| regulation of cellular catabolic process | GO:0031329 | 157 | 0.043 | |
| ncrna metabolic process | GO:0034660 | 43 | 0.043 | |
| positive regulation of developmental process | GO:0051094 | 143 | 0.043 | |
| protein acylation | GO:0043543 | 42 | 0.043 | |
| regulation of chromatin silencing | GO:0031935 | 36 | 0.042 | |
| oxoacid metabolic process | GO:0043436 | 103 | 0.042 | |
| eggshell chorion assembly | GO:0007306 | 66 | 0.042 | |
| cellular macromolecule localization | GO:0070727 | 220 | 0.042 | |
| columnar cuboidal epithelial cell differentiation | GO:0002065 | 256 | 0.041 | |
| axon guidance | GO:0007411 | 233 | 0.040 | |
| rna processing | GO:0006396 | 147 | 0.040 | |
| embryonic development via the syncytial blastoderm | GO:0001700 | 148 | 0.040 | |
| organic substance catabolic process | GO:1901575 | 308 | 0.039 | |
| cellular protein modification process | GO:0006464 | 438 | 0.039 | |
| programmed cell death | GO:0012501 | 257 | 0.039 | |
| catabolic process | GO:0009056 | 409 | 0.037 | |
| mitotic cell cycle embryonic | GO:0045448 | 38 | 0.036 | |
| cellular component assembly involved in morphogenesis | GO:0010927 | 151 | 0.035 | |
| mitotic cell cycle phase transition | GO:0044772 | 138 | 0.035 | |
| apoptotic process | GO:0006915 | 159 | 0.035 | |
| axonogenesis | GO:0007409 | 290 | 0.035 | |
| cellular response to organic substance | GO:0071310 | 132 | 0.035 | |
| protein import into nucleus | GO:0006606 | 51 | 0.034 | |
| guanosine containing compound catabolic process | GO:1901069 | 74 | 0.034 | |
| histone acetylation | GO:0016573 | 38 | 0.033 | |
| positive regulation of growth | GO:0045927 | 75 | 0.033 | |
| negative regulation of cellular biosynthetic process | GO:0031327 | 277 | 0.033 | |
| mrna metabolic process | GO:0016071 | 124 | 0.033 | |
| regulation of organelle organization | GO:0033043 | 196 | 0.033 | |
| negative regulation of response to stimulus | GO:0048585 | 258 | 0.032 | |
| chromatin assembly or disassembly | GO:0006333 | 52 | 0.032 | |
| exocrine system development | GO:0035272 | 162 | 0.032 | |
| defense response to other organism | GO:0098542 | 225 | 0.032 | |
| regulation of molecular function | GO:0065009 | 217 | 0.032 | |
| dna metabolic process | GO:0006259 | 227 | 0.032 | Yeast |
| enzyme linked receptor protein signaling pathway | GO:0007167 | 179 | 0.032 | |
| peptidyl lysine acetylation | GO:0018394 | 39 | 0.031 | |
| negative regulation of signal transduction | GO:0009968 | 206 | 0.030 | |
| negative regulation of developmental process | GO:0051093 | 201 | 0.030 | |
| compound eye development | GO:0048749 | 307 | 0.030 | |
| regulation of programmed cell death | GO:0043067 | 152 | 0.030 | |
| negative regulation of cell death | GO:0060548 | 81 | 0.030 | |
| negative regulation of transcription from rna polymerase ii promoter | GO:0000122 | 119 | 0.030 | |
| cell proliferation | GO:0008283 | 299 | 0.029 | |
| protein modification process | GO:0036211 | 438 | 0.029 | |
| columnar cuboidal epithelial cell development | GO:0002066 | 249 | 0.029 | |
| single organism biosynthetic process | GO:0044711 | 206 | 0.029 | |
| positive regulation of cell communication | GO:0010647 | 250 | 0.028 | |
| negative regulation of nucleobase containing compound metabolic process | GO:0045934 | 261 | 0.028 | |
| regulation of cell proliferation | GO:0042127 | 163 | 0.028 | |
| digestive system development | GO:0055123 | 149 | 0.028 | |
| morphogenesis of embryonic epithelium | GO:0016331 | 94 | 0.027 | |
| protein localization to organelle | GO:0033365 | 82 | 0.027 | |
| cellular response to chemical stimulus | GO:0070887 | 199 | 0.027 | |
| negative regulation of cell differentiation | GO:0045596 | 143 | 0.027 | |
| chorion containing eggshell formation | GO:0007304 | 105 | 0.027 | |
| carboxylic acid metabolic process | GO:0019752 | 92 | 0.026 | |
| positive regulation of multicellular organismal process | GO:0051240 | 143 | 0.026 | |
| neuron fate commitment | GO:0048663 | 50 | 0.026 | |
| negative regulation of signaling | GO:0023057 | 219 | 0.026 | |
| ribose phosphate metabolic process | GO:0019693 | 145 | 0.026 | |
| antimicrobial humoral response | GO:0019730 | 99 | 0.025 | |
| anterior posterior pattern specification | GO:0009952 | 136 | 0.025 | |
| wing disc morphogenesis | GO:0007472 | 344 | 0.025 | |
| male meiosis | GO:0007140 | 52 | 0.025 | |
| tissue migration | GO:0090130 | 155 | 0.025 | |
| regulation of apoptotic process | GO:0042981 | 130 | 0.025 | |
| peptidyl amino acid modification | GO:0018193 | 105 | 0.025 | |
| positive regulation of signaling | GO:0023056 | 243 | 0.024 | |
| eye development | GO:0001654 | 323 | 0.024 | |
| embryo development ending in birth or egg hatching | GO:0009792 | 152 | 0.024 | |
| regulation of protein catabolic process | GO:0042176 | 55 | 0.024 | |
| cellular macromolecule catabolic process | GO:0044265 | 136 | 0.024 | |
| positive regulation of signal transduction | GO:0009967 | 223 | 0.024 | |
| phagocytosis | GO:0006909 | 215 | 0.024 | |
| protein import | GO:0017038 | 55 | 0.024 | |
| dna damage checkpoint | GO:0000077 | 78 | 0.024 | |
| cellular macromolecular complex assembly | GO:0034622 | 153 | 0.023 | |
| negative regulation of apoptotic process | GO:0043066 | 63 | 0.023 | |
| regulation of proteolysis involved in cellular protein catabolic process | GO:1903050 | 44 | 0.023 | |
| organic acid metabolic process | GO:0006082 | 103 | 0.022 | |
| salivary gland cell autophagic cell death | GO:0035071 | 83 | 0.022 | |
| carbohydrate derivative biosynthetic process | GO:1901137 | 85 | 0.022 | |
| cellular ketone metabolic process | GO:0042180 | 24 | 0.022 | |
| negative regulation of programmed cell death | GO:0043069 | 72 | 0.021 | |
| regulation of cell differentiation | GO:0045595 | 302 | 0.021 | |
| histolysis | GO:0007559 | 102 | 0.021 | |
| regulation of embryonic development | GO:0045995 | 68 | 0.021 | |
| humoral immune response | GO:0006959 | 117 | 0.021 | |
| open tracheal system development | GO:0007424 | 204 | 0.020 | |
| stem cell division | GO:0017145 | 69 | 0.020 | |
| regulation of developmental growth | GO:0048638 | 174 | 0.020 | |
| salivary gland development | GO:0007431 | 162 | 0.020 | |
| cell death | GO:0008219 | 279 | 0.019 | |
| mitotic spindle organization | GO:0007052 | 220 | 0.019 | |
| spindle organization | GO:0007051 | 253 | 0.019 | |
| ovarian follicle cell development | GO:0030707 | 248 | 0.019 | |
| spermatogenesis | GO:0007283 | 200 | 0.019 | Rat |
| purine ribonucleoside triphosphate catabolic process | GO:0009207 | 108 | 0.019 | |
| organelle fission | GO:0048285 | 340 | 0.019 | |
| neuroblast proliferation | GO:0007405 | 74 | 0.019 | |
| nucleoside phosphate catabolic process | GO:1901292 | 110 | 0.019 | |
| salivary gland morphogenesis | GO:0007435 | 145 | 0.018 | |
| histone h3 acetylation | GO:0043966 | 11 | 0.018 | |
| small molecule metabolic process | GO:0044281 | 305 | 0.018 | |
| branching morphogenesis of an epithelial tube | GO:0048754 | 45 | 0.018 | |
| reproductive system development | GO:0061458 | 74 | 0.018 | |
| regulation of anatomical structure morphogenesis | GO:0022603 | 242 | 0.018 | |
| single organism intracellular transport | GO:1902582 | 207 | 0.018 | |
| salivary gland histolysis | GO:0035070 | 88 | 0.018 | |
| protein acetylation | GO:0006473 | 39 | 0.018 | |
| regulation of catalytic activity | GO:0050790 | 185 | 0.017 | |
| intracellular protein transport | GO:0006886 | 104 | 0.017 | |
| chromosome segregation | GO:0007059 | 157 | 0.017 | |
| regulation of transmembrane receptor protein serine threonine kinase signaling pathway | GO:0090092 | 38 | 0.017 | |
| purine ribonucleotide catabolic process | GO:0009154 | 109 | 0.017 | |
| anatomical structure homeostasis | GO:0060249 | 97 | 0.017 | |
| regulation of chromosome organization | GO:0033044 | 64 | 0.017 | |
| multicellular organism growth | GO:0035264 | 46 | 0.017 | |
| sensory organ morphogenesis | GO:0090596 | 260 | 0.017 | |
| regulation of multicellular organism growth | GO:0040014 | 40 | 0.017 | |
| eggshell formation | GO:0030703 | 105 | 0.017 | |
| reproductive structure development | GO:0048608 | 74 | 0.017 | |
| positive regulation of cell proliferation | GO:0008284 | 47 | 0.017 | |
| muscle organ development | GO:0007517 | 127 | 0.017 | |
| cellular amino acid metabolic process | GO:0006520 | 61 | 0.017 | |
| purine nucleoside metabolic process | GO:0042278 | 127 | 0.016 | |
| regulation of cellular protein metabolic process | GO:0032268 | 243 | 0.016 | |
| sister chromatid segregation | GO:0000819 | 92 | 0.016 | |
| cardiovascular system development | GO:0072358 | 82 | 0.016 | |
| epithelium migration | GO:0090132 | 148 | 0.016 | |
| regulation of wnt signaling pathway | GO:0030111 | 68 | 0.016 | |
| gland development | GO:0048732 | 191 | 0.016 | |
| regulation of tube architecture open tracheal system | GO:0035152 | 68 | 0.016 | |
| cellular amide metabolic process | GO:0043603 | 80 | 0.016 | |
| aromatic compound catabolic process | GO:0019439 | 166 | 0.016 | |
| protein localization to chromatin | GO:0071168 | 3 | 0.016 | |
| nucleobase containing compound catabolic process | GO:0034655 | 165 | 0.016 | |
| regulation of localization | GO:0032879 | 275 | 0.016 | |
| cellular response to biotic stimulus | GO:0071216 | 4 | 0.016 | |
| respiratory system development | GO:0060541 | 213 | 0.016 | |
| brain development | GO:0007420 | 120 | 0.015 | |
| vesicle mediated transport | GO:0016192 | 381 | 0.015 | |
| r7 cell differentiation | GO:0045466 | 43 | 0.015 | |
| hindgut morphogenesis | GO:0007442 | 58 | 0.015 | |
| establishment or maintenance of cell polarity | GO:0007163 | 167 | 0.015 | |
| dorsal appendage formation | GO:0046843 | 47 | 0.015 | |
| cuticle development | GO:0042335 | 86 | 0.015 | |
| regulation of cellular protein catabolic process | GO:1903362 | 44 | 0.015 | |
| chemotaxis | GO:0006935 | 249 | 0.015 | |
| cell cycle comprising mitosis without cytokinesis | GO:0033301 | 25 | 0.015 | |
| response to bacterium | GO:0009617 | 198 | 0.015 | |
| cellular catabolic process | GO:0044248 | 372 | 0.015 | |
| regulation of protein metabolic process | GO:0051246 | 256 | 0.015 | |
| regulation of cell division | GO:0051302 | 72 | 0.015 | |
| posttranscriptional regulation of gene expression | GO:0010608 | 145 | 0.015 | |
| post embryonic appendage morphogenesis | GO:0035120 | 385 | 0.015 | |
| protein transport | GO:0015031 | 155 | 0.014 | |
| single organism catabolic process | GO:0044712 | 228 | 0.014 | |
| actin cytoskeleton organization | GO:0030036 | 206 | 0.014 | |
| response to fungus | GO:0009620 | 50 | 0.014 | |
| imaginal disc pattern formation | GO:0007447 | 91 | 0.014 | |
| segmentation | GO:0035282 | 207 | 0.014 | |
| single organism behavior | GO:0044708 | 391 | 0.014 | |
| digestive tract morphogenesis | GO:0048546 | 127 | 0.014 | |
| intracellular transport | GO:0046907 | 228 | 0.014 | |
| regulation of response to external stimulus | GO:0032101 | 115 | 0.013 | |
| single organism nuclear import | GO:1902593 | 51 | 0.013 | |
| somatic stem cell division | GO:0048103 | 37 | 0.013 | |
| organic cyclic compound catabolic process | GO:1901361 | 168 | 0.013 | |
| g1 s transition of mitotic cell cycle | GO:0000082 | 31 | 0.013 | |
| epithelial cell development | GO:0002064 | 274 | 0.013 | |
| protein processing | GO:0016485 | 68 | 0.013 | |
| nucleoside metabolic process | GO:0009116 | 127 | 0.013 | |
| regulation of response to biotic stimulus | GO:0002831 | 63 | 0.013 | |
| telencephalon development | GO:0021537 | 2 | 0.013 | |
| digestive tract development | GO:0048565 | 149 | 0.013 | |
| tissue death | GO:0016271 | 102 | 0.013 | |
| photoreceptor cell fate commitment | GO:0046552 | 41 | 0.013 | |
| ameboidal type cell migration | GO:0001667 | 151 | 0.013 | |
| regulation of proteasomal protein catabolic process | GO:0061136 | 39 | 0.013 | |
| chaeta development | GO:0022416 | 97 | 0.013 | |
| epithelial cell migration | GO:0010631 | 148 | 0.013 | |
| cell cycle g1 s phase transition | GO:0044843 | 31 | 0.012 | |
| chitin based cuticle development | GO:0040003 | 49 | 0.012 | |
| protein catabolic process | GO:0030163 | 101 | 0.012 | |
| establishment of protein localization to organelle | GO:0072594 | 62 | 0.012 | |
| cell fate specification | GO:0001708 | 71 | 0.012 | |
| macromolecule catabolic process | GO:0009057 | 161 | 0.012 | |
| dna conformation change | GO:0071103 | 105 | 0.012 | |
| positive regulation of cellular catabolic process | GO:0031331 | 95 | 0.012 | |
| proteolysis | GO:0006508 | 192 | 0.012 | |
| cellular response to organic cyclic compound | GO:0071407 | 32 | 0.012 | |
| glycosyl compound metabolic process | GO:1901657 | 127 | 0.012 | |
| negative regulation of cell cycle | GO:0045786 | 116 | 0.012 | |
| positive regulation of multicellular organism growth | GO:0040018 | 21 | 0.012 | |
| tube morphogenesis | GO:0035239 | 191 | 0.012 | |
| cell motility | GO:0048870 | 251 | 0.011 | |
| positive regulation of intracellular signal transduction | GO:1902533 | 116 | 0.011 | |
| camera type eye development | GO:0043010 | 4 | 0.011 | |
| heterocycle catabolic process | GO:0046700 | 166 | 0.011 | |
| purine ribonucleoside catabolic process | GO:0046130 | 112 | 0.011 | |
| establishment of localization in cell | GO:0051649 | 402 | 0.011 | |
| apoptotic signaling pathway | GO:0097190 | 27 | 0.011 | |
| circulatory system development | GO:0072359 | 82 | 0.011 | |
| reciprocal dna recombination | GO:0035825 | 19 | 0.011 | |
| cellular response to dna damage stimulus | GO:0006974 | 223 | 0.011 | |
| chaeta morphogenesis | GO:0008407 | 42 | 0.011 | |
| establishment of planar polarity | GO:0001736 | 87 | 0.011 | |
| nitrogen compound transport | GO:0071705 | 85 | 0.011 | |
| regulation of cellular amine metabolic process | GO:0033238 | 3 | 0.011 | |
| cell cycle phase transition | GO:0044770 | 140 | 0.011 | |
| male sex differentiation | GO:0046661 | 25 | 0.010 | |
| internal peptidyl lysine acetylation | GO:0018393 | 38 | 0.010 | |
| transmembrane receptor protein serine threonine kinase signaling pathway | GO:0007178 | 65 | 0.010 | |
| meiotic dna double strand break formation | GO:0042138 | 1 | 0.010 | |
| regulation of intracellular signal transduction | GO:1902531 | 236 | 0.010 | |
| regulation of cellular ketone metabolic process | GO:0010565 | 3 | 0.010 | |
| positive regulation of cellular amine metabolic process | GO:0033240 | 0 | 0.010 | |
