Drosophila melanogaster

55 known processes

opa1-like (Dmel_CG8479)

optic atrophy 1-like

(Aliases: CG8479,dOPA1,OPA1,OPA1-like,Opa1-like,Dmel\CG8479,opa1,l(2)s3475,Opa1,dOpa1)

opa1-like biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
regulation of mitochondrial fusionGO:001063550.716
mitochondrion organizationGO:0007005650.684
regulation of mitochondrion organizationGO:0010821120.604
mitochondrial fissionGO:000026680.581
sperm mitochondrion organizationGO:003038270.379
regulation of mitochondrial fissionGO:009014070.303
transmembrane transportGO:00550851390.299
positive regulation of mitochondrion organizationGO:001082280.277
mitochondrion morphogenesisGO:007058480.262
mitochondrial fusionGO:000805370.256
regulation of transcription from rna polymerase ii promoterGO:00063573780.251
transcription from rna polymerase ii promoterGO:00063663680.166
small molecule metabolic processGO:00442813050.156
mitotic g2 m transition checkpointGO:0044818700.140
negative regulation of mitotic cell cycle phase transitionGO:19019911030.135
regulation of cell deathGO:00109411730.130
mitotic dna damage checkpointGO:0044773740.129
cytoplasmic transportGO:00164821300.125
heterocycle catabolic processGO:00467001660.118
positive regulation of nitrogen compound metabolic processGO:00511733540.107
eye developmentGO:00016543230.103
g2 dna damage checkpointGO:0031572690.097
deathGO:00162652840.095
mitotic g2 dna damage checkpointGO:0007095690.092
circulatory system processGO:0003013370.091
single organism intracellular transportGO:19025822070.091
cation transportGO:00068121100.087
regulation of protein depolymerizationGO:1901879270.084
compound eye developmentGO:00487493070.081
protein localizationGO:00081042840.080
regulation of anatomical structure morphogenesisGO:00226032420.079
cell deathGO:00082192790.074
regulation of nervous system developmentGO:00519602480.074
heart processGO:0003015370.072
mitotic dna integrity checkpointGO:0044774750.067
wnt signaling pathwayGO:0016055980.067
tube morphogenesisGO:00352391910.065
organelle fissionGO:00482853400.064
establishment or maintenance of cell polarityGO:00071631670.064
regulation of protein complex disassemblyGO:0043244290.062
negative regulation of protein depolymerizationGO:1901880230.062
metal ion transportGO:0030001740.060
cellular protein complex disassemblyGO:0043624350.060
ion transportGO:00068111450.059
negative regulation of cytoskeleton organizationGO:0051494300.059
heart contractionGO:0060047260.058
camera type eye developmentGO:004301040.057
dna damage checkpointGO:0000077780.057
lipid homeostasisGO:0055088330.056
mitochondrion degradationGO:000042280.056
cellular amino acid metabolic processGO:0006520610.055
establishment of mitochondrion localizationGO:005165470.055
cation transmembrane transportGO:0098655880.053
regulation of programmed cell deathGO:00430671520.052
ethanolamine containing compound metabolic processGO:004243940.051
negative regulation of cell cycle phase transitionGO:19019881030.050
metal ion homeostasisGO:0055065440.047
negative regulation of microtubule polymerization or depolymerizationGO:0031111210.047
er nucleus signaling pathwayGO:000698490.046
organic acid metabolic processGO:00060821030.046
establishment of localization in cellGO:00516494020.044
oxoacid metabolic processGO:00434361030.044
response to abiotic stimulusGO:00096283410.044
regionalizationGO:00030024160.044
carboxylic acid metabolic processGO:0019752920.043
central nervous system developmentGO:00074172010.043
blood circulationGO:0008015260.043
organonitrogen compound metabolic processGO:19015643180.043
single organism behaviorGO:00447083910.042
chaeta developmentGO:0022416970.041
single organism cellular localizationGO:19025801800.040
negative regulation of organelle organizationGO:0010639560.040
imaginal disc derived wing morphogenesisGO:00074763370.040
regulation of heart rateGO:0002027110.039
mitotic cell cycle checkpointGO:0007093880.039
dna integrity checkpointGO:0031570810.039
imaginal disc derived appendage morphogenesisGO:00351143950.039
oxidation reduction processGO:00551141230.038
locomotory behaviorGO:00076261760.038
neural retina developmentGO:000340740.038
macromolecular complex disassemblyGO:0032984370.038
regulation of membrane potentialGO:0042391350.038
response to external biotic stimulusGO:00432072930.037
body morphogenesisGO:001017120.037
retina development in camera type eyeGO:006004140.037
positive regulation of nucleobase containing compound metabolic processGO:00459353320.037
ion transmembrane transportGO:00342201220.037
compound eye morphogenesisGO:00017452490.036
cellular response to sterol depletionGO:007150130.035
proteolysisGO:00065081920.035
response to temperature stimulusGO:00092661060.035
apoptotic processGO:00069151590.034
cell proliferationGO:00082832990.034
calcium ion transmembrane transportGO:0070588170.033
endoplasmic reticulum organizationGO:0007029130.033
positive regulation of phosphorus metabolic processGO:00105621390.033
eye morphogenesisGO:00485922600.033
generation of precursor metabolites and energyGO:0006091420.032
negative regulation of microtubule depolymerizationGO:0007026210.032
positive regulation of rna metabolic processGO:00512542710.031
regulation of multicellular organismal developmentGO:20000264140.031
negative regulation of cell cycle processGO:00109481090.031
positive regulation of organelle organizationGO:0010638650.031
negative regulation of response to stimulusGO:00485852580.031
cell migrationGO:00164772380.030
positive regulation of macromolecule metabolic processGO:00106044050.030
membrane organizationGO:00610241120.030
programmed cell deathGO:00125012570.030
negative regulation of cell deathGO:0060548810.030
cell agingGO:000756920.029
single organism membrane organizationGO:0044802930.029
macromolecular complex assemblyGO:00650032560.029
cell cycle checkpointGO:0000075950.029
wing disc morphogenesisGO:00074723440.028
positive regulation of cell motilityGO:200014730.028
regulation of intracellular signal transductionGO:19025312360.028
protein complex biogenesisGO:00702712010.028
positive regulation of hydrolase activityGO:0051345780.027
immune system processGO:00023763470.027
regulation of hydrolase activityGO:0051336970.027
positive regulation of cellular component organizationGO:00511301560.027
epidermis developmentGO:0008544650.026
epithelial cell differentiationGO:00308553220.026
response to biotic stimulusGO:00096072940.026
regulation of catalytic activityGO:00507901850.026
lipid metabolic processGO:00066291210.026
phagocytosisGO:00069092150.026
purine ribonucleoside metabolic processGO:00461281270.026
endocytosisGO:00068973100.026
camera type eye morphogenesisGO:004859320.025
organelle localizationGO:00516401480.025
regulation of heart contractionGO:0008016210.025
regulation of cellular amine metabolic processGO:003323830.025
positive regulation of biosynthetic processGO:00098913160.025
regulation of microtubule based processGO:0032886490.024
agingGO:00075681430.024
response to superoxideGO:000030330.024
potassium ion transportGO:0006813200.024
cellular protein localizationGO:00346131600.024
organelle assemblyGO:00709251980.024
synaptic vesicle transportGO:0048489500.024
regulation of cellular component movementGO:0051270420.024
chemical homeostasisGO:0048878920.023
negative regulation of programmed cell deathGO:0043069720.023
organic hydroxy compound biosynthetic processGO:1901617210.023
regulation of transportGO:00510491810.023
atp metabolic processGO:0046034490.023
positive regulation of gene expressionGO:00106282900.022
regulation of localizationGO:00328792750.022
negative regulation of nucleic acid templated transcriptionGO:19035072400.022
regulation of transmembrane transportGO:0034762270.022
regulation of cell developmentGO:00602842150.021
negative regulation of apoptotic processGO:0043066630.021
positive regulation of macromolecule biosynthetic processGO:00105572830.021
negative regulation of growthGO:0045926840.021
purine ribonucleoside monophosphate metabolic processGO:0009167500.020
negative regulation of protein complex disassemblyGO:0043242230.020
protein maturationGO:0051604710.020
nucleobase containing compound catabolic processGO:00346551650.020
organic substance transportGO:00717022570.020
alditol phosphate metabolic processGO:005264620.020
post embryonic appendage morphogenesisGO:00351203850.020
regulation of cell cycle phase transitionGO:19019871300.020
positive regulation of response to stimulusGO:00485843230.020
neuronal action potentialGO:0019228100.020
nucleoside triphosphate catabolic processGO:00091431080.020
protein depolymerizationGO:0051261310.020
cell cycle phase transitionGO:00447701400.019
purine containing compound metabolic processGO:00725211550.019
protein complex disassemblyGO:0043241360.019
cellular response to dna damage stimulusGO:00069742230.019
phosphatidylcholine metabolic processGO:004647030.019
monovalent inorganic cation transportGO:0015672400.019
establishment of planar polarityGO:0001736870.019
positive regulation of catalytic activityGO:00430851180.019
positive regulation of catabolic processGO:00098961050.019
nucleus organizationGO:0006997450.019
cell cycle arrestGO:000705040.019
cellular macromolecular complex assemblyGO:00346221530.019
retrograde axon cargo transportGO:000809090.019
cellular amine metabolic processGO:0044106120.018
negative regulation of cellular component organizationGO:00511291080.018
regulation of blood circulationGO:1903522210.018
positive regulation of programmed cell deathGO:0043068620.018
regulation of molecular functionGO:00650092170.018
transmission of nerve impulseGO:0019226120.018
organophosphate metabolic processGO:00196371950.018
homeostatic processGO:00425921990.018
endomembrane system organizationGO:00102561190.018
tube developmentGO:00352952440.018
intracellular signal transductionGO:00355563000.018
cellular macromolecule localizationGO:00707272200.018
morphogenesis of an epitheliumGO:00020092760.018
embryo development ending in birth or egg hatchingGO:00097921520.018
brain developmentGO:00074201200.018
single organism biosynthetic processGO:00447112060.017
spindle organizationGO:00070512530.017
regulation of mitotic cell cycle phase transitionGO:19019901300.017
positive regulation of nucleic acid templated transcriptionGO:19035082660.017
adult locomotory behaviorGO:0008344760.017
negative regulation of cell communicationGO:00106482230.017
protein processingGO:0016485680.017
meiotic cell cycleGO:00513211710.017
positive regulation of cellular biosynthetic processGO:00313283160.017
nucleotide catabolic processGO:00091661090.017
divalent metal ion transportGO:0070838260.017
cellular catabolic processGO:00442483720.017
wound healingGO:0042060750.017
cellularizationGO:0007349900.016
positive regulation of signalingGO:00230562430.016
regulation of phosphate metabolic processGO:00192202100.016
regulation of cell cycle processGO:00105641810.016
negative regulation of macromolecule biosynthetic processGO:00105582700.016
mitochondrion localizationGO:0051646170.016
negative regulation of mitotic cell cycleGO:00459301090.016
embryonic morphogenesisGO:00485982060.016
positive regulation of developmental processGO:00510941430.016
negative regulation of multicellular organismal processGO:00512411420.016
inorganic cation transmembrane transportGO:0098662610.016
skin developmentGO:0043588650.016
phosphorylationGO:00163102940.015
positive regulation of cellular catabolic processGO:0031331950.015
establishment of organelle localizationGO:00516561220.015
ameboidal type cell migrationGO:00016671510.015
regulation of organelle organizationGO:00330431960.015
anion homeostasisGO:005508130.015
intracellular transportGO:00469072280.015
response to woundingGO:0009611940.015
protein transportGO:00150311550.014
alcohol biosynthetic processGO:0046165140.014
positive regulation of signal transductionGO:00099672230.014
glial cell differentiationGO:0010001350.014
neuron deathGO:0070997270.014
appendage morphogenesisGO:00351073970.014
purine nucleoside monophosphate metabolic processGO:0009126500.014
protein ubiquitinationGO:0016567700.014
spermatogenesisGO:00072832000.014
aromatic compound catabolic processGO:00194391660.014
localization of cellGO:00516742570.014
nuclear transportGO:0051169720.014
cellular respirationGO:0045333260.014
regulation of developmental pigmentationGO:0048070240.014
regulation of neuron deathGO:1901214260.014
adult somatic muscle developmentGO:0007527140.014
amine metabolic processGO:0009308120.014
spindle assemblyGO:0051225800.014
cellular macromolecule catabolic processGO:00442651360.014
response to other organismGO:00517072930.014
protein catabolic processGO:00301631010.013
regulation of execution phase of apoptosisGO:190011750.013
negative regulation of gene expressionGO:00106293870.013
endodermal cell differentiationGO:003598730.013
multicellular organismal agingGO:00102591400.013
positive regulation of purine nucleotide catabolic processGO:0033123460.013
organic acid catabolic processGO:0016054160.013
positive regulation of molecular functionGO:00440931360.013
axon cargo transportGO:0008088290.013
response to copper ionGO:004668840.013
zymogen activationGO:0031638200.013
regulation of retinal cell programmed cell deathGO:0046668180.013
actin polymerization or depolymerizationGO:0008154310.013
regulation of mitotic cell cycleGO:00073461900.013
cellular response to topologically incorrect proteinGO:0035967100.013
inositol lipid mediated signalingGO:004801740.013
establishment of protein localizationGO:00451841630.013
ribonucleoside monophosphate metabolic processGO:0009161510.012
regulation of apoptotic processGO:00429811300.012
response to oxygen radicalGO:000030530.012
fatty acid homeostasisGO:005508920.012
positive regulation of nucleoside metabolic processGO:0045979470.012
regulation of wnt signaling pathwayGO:0030111680.012
imaginal disc derived wing hair organizationGO:0035317450.012
asymmetric stem cell divisionGO:0098722490.012
regulation of ion transmembrane transportGO:0034765270.012
regulation of anatomical structure sizeGO:00900661630.012
regulation of microtubule polymerization or depolymerizationGO:0031110270.012
vesicle mediated transportGO:00161923810.012
catabolic processGO:00090564090.012
male gamete generationGO:00482322010.012
pole cell formationGO:0007279190.012
regulation of gtpase activityGO:0043087440.012
positive regulation of cell deathGO:0010942690.012
negative regulation of neuron apoptotic processGO:0043524140.012
negative regulation of cellular biosynthetic processGO:00313272770.012
asymmetric protein localizationGO:0008105330.012
glycosyl compound metabolic processGO:19016571270.012
protein heterooligomerizationGO:005129140.012
endoderm formationGO:000170630.012
imaginal disc derived appendage developmentGO:00487373990.012
regulation of cell cycleGO:00517262910.012
erbb signaling pathwayGO:0038127580.011
microtubule depolymerizationGO:0007019250.011
cellular component disassemblyGO:0022411460.011
purine nucleoside triphosphate metabolic processGO:00091441190.011
positive regulation of apoptotic processGO:0043065470.011
ncrna metabolic processGO:0034660430.011
regulation of transferase activityGO:0051338580.011
neuroblast proliferationGO:0007405740.011
response to decreased oxygen levelsGO:0036293580.011
microtubule based movementGO:0007018510.011
regulation of ion transportGO:0043269390.011
nuclear divisionGO:00002803320.011
organonitrogen compound biosynthetic processGO:19015661170.011
positive regulation of rna biosynthetic processGO:19026802660.011
energy derivation by oxidation of organic compoundsGO:0015980320.011
secretionGO:00469031090.011
epithelial cell developmentGO:00020642740.011
cellular response to chemical stimulusGO:00708871990.011
glycosyl compound catabolic processGO:19016581120.011
negative regulation of epithelial cell proliferationGO:005068040.011
organophosphate catabolic processGO:00464341120.011
humoral immune responseGO:00069591170.011
regulation of microtubule cytoskeleton organizationGO:0070507410.011
mitochondrion transport along microtubuleGO:004749750.011
defense responseGO:00069523000.011
microtubule polymerization or depolymerizationGO:0031109390.011
developmental programmed cell deathGO:00106231380.011
purine nucleoside triphosphate catabolic processGO:00091461080.011
cellular amide metabolic processGO:0043603800.011
germ cell migrationGO:0008354430.011
regulation of response to oxidative stressGO:190288240.011
negative regulation of cell proliferationGO:0008285690.010
lipid biosynthetic processGO:0008610460.010
regulation of system processGO:0044057360.010
multicellular organismal signalingGO:0035637120.010
leg disc developmentGO:0035218920.010
muscle tissue morphogenesisGO:006041520.010
response to endoplasmic reticulum stressGO:0034976280.010
nuclear dna replicationGO:003326010.010
negative regulation of cell differentiationGO:00455961430.010
purine containing compound biosynthetic processGO:0072522300.010

opa1-like disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.054
disease of cellular proliferationDOID:1456600.054
organ system cancerDOID:005068600.054
disease of anatomical entityDOID:700.048
nervous system diseaseDOID:86300.032
central nervous system diseaseDOID:33100.020
neurodegenerative diseaseDOID:128900.019
musculoskeletal system diseaseDOID:1700.017
muscular diseaseDOID:008000000.017
myopathyDOID:42300.012
heart diseaseDOID:11400.012
cardiomyopathyDOID:005070000.012
intrinsic cardiomyopathyDOID:006003600.012
cardiovascular system diseaseDOID:128700.012
muscle tissue diseaseDOID:6600.012
parkinson s diseaseDOID:1433000.011
synucleinopathyDOID:005089000.011