IMP: Integrative Multi-species Prediction

Drosophila melanogaster

66 known processes

bip2 (Dmel_CG2009)

CG2009 gene product from transcript CG2009-RA

(Aliases: BIP2,TAF3,Bip2,Dmel\CG2009,TAF155,DmTAF3,dTAFII3,i163,TFIID,TAFII155,CG2009,i31,TAF[[II]]155,dBIP2,bip-II,dTAF[[II]]155)

FLYBASE: FBgn0026262
Entrez: 43793
UniProtKB: Q9V4D4

Process Predictions
Disease Predictions

bip2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability	Func Analog Org
dendrite development	GO:0016358	204	0.551
wing disc morphogenesis	GO:0007472	344	0.498
eye development	GO:0001654	323	0.452
negative regulation of cellular macromolecule biosynthetic process	GO:2000113	267	0.443	Human Mouse
axonogenesis	GO:0007409	290	0.370
regulation of protein metabolic process	GO:0051246	256	0.362
dendrite morphogenesis	GO:0048813	199	0.340
post embryonic appendage morphogenesis	GO:0035120	385	0.325
negative regulation of cellular biosynthetic process	GO:0031327	277	0.295	Human Mouse
locomotory behavior	GO:0007626	176	0.284
negative regulation of macromolecule biosynthetic process	GO:0010558	270	0.279	Human Mouse
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.262	Human Mouse
negative regulation of transcription dna templated	GO:0045892	237	0.259	Human Mouse
death	GO:0016265	284	0.258
regulation of cell shape	GO:0008360	113	0.236
negative regulation of biosynthetic process	GO:0009890	277	0.227	Human Mouse
axon development	GO:0061564	297	0.223
compound eye morphogenesis	GO:0001745	249	0.218
blastoderm segmentation	GO:0007350	159	0.182
multicellular organismal reproductive behavior	GO:0033057	110	0.172
imaginal disc derived appendage development	GO:0048737	399	0.171
negative regulation of gene expression	GO:0010629	387	0.169	Human Mouse
embryonic pattern specification	GO:0009880	174	0.163
regionalization	GO:0003002	416	0.149
regulation of anatomical structure morphogenesis	GO:0022603	242	0.139
salivary gland morphogenesis	GO:0007435	145	0.135
positive regulation of wnt signaling pathway	GO:0030177	25	0.133
taxis	GO:0042330	304	0.131
dna packaging	GO:0006323	91	0.131
male gamete generation	GO:0048232	201	0.124
oocyte differentiation	GO:0009994	145	0.120
appendage development	GO:0048736	401	0.117
sensory organ morphogenesis	GO:0090596	260	0.111
epithelial cell differentiation	GO:0030855	322	0.111
inter male aggressive behavior	GO:0002121	60	0.109
segmentation	GO:0035282	207	0.109
cell recognition	GO:0008037	102	0.107
negative regulation of rna biosynthetic process	GO:1902679	240	0.105	Human Mouse
oocyte axis specification	GO:0007309	108	0.098
phagocytosis	GO:0006909	215	0.098
melanin metabolic process	GO:0006582	47	0.097
olfactory behavior	GO:0042048	97	0.095
imaginal disc derived wing morphogenesis	GO:0007476	337	0.094
single organism behavior	GO:0044708	391	0.093
germarium derived egg chamber formation	GO:0007293	101	0.091
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.091
vesicle mediated transport	GO:0016192	381	0.091
embryonic axis specification	GO:0000578	107	0.089
programmed cell death	GO:0012501	257	0.089
negative regulation of nucleobase containing compound metabolic process	GO:0045934	261	0.089	Human Mouse
salivary gland development	GO:0007431	162	0.088
cellular component assembly involved in morphogenesis	GO:0010927	151	0.088
compound eye cone cell fate commitment	GO:0042676	5	0.086
regulation of cellular protein metabolic process	GO:0032268	243	0.084
oocyte development	GO:0048599	124	0.084
appendage morphogenesis	GO:0035107	397	0.083
oocyte construction	GO:0007308	112	0.080
neuron recognition	GO:0008038	101	0.079
establishment or maintenance of cell polarity	GO:0007163	167	0.079
organelle assembly	GO:0070925	198	0.079
columnar cuboidal epithelial cell development	GO:0002066	249	0.076
epithelial cell development	GO:0002064	274	0.076
compound eye cone cell differentiation	GO:0042675	13	0.076
establishment of protein localization to membrane	GO:0090150	11	0.075
embryo development ending in birth or egg hatching	GO:0009792	152	0.073
positive regulation of molecular function	GO:0044093	136	0.073
negative regulation of cell cycle phase transition	GO:1901988	103	0.071
positive regulation of signaling	GO:0023056	243	0.071
mushroom body development	GO:0016319	70	0.069
body morphogenesis	GO:0010171	2	0.066
actin filament based process	GO:0030029	220	0.064
cell death	GO:0008219	279	0.064
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.064
endocytosis	GO:0006897	310	0.063
positive regulation of cell communication	GO:0010647	250	0.063
brain development	GO:0007420	120	0.063
protein transport	GO:0015031	155	0.062
eye morphogenesis	GO:0048592	260	0.061
central nervous system development	GO:0007417	201	0.061
cognition	GO:0050890	141	0.059
chemosensory behavior	GO:0007635	106	0.058
positive regulation of macromolecule metabolic process	GO:0010604	405	0.057
regulation of chromatin silencing	GO:0031935	36	0.057
anterior posterior axis specification	GO:0009948	109	0.057
tripartite regional subdivision	GO:0007351	103	0.055
regulation of translation	GO:0006417	56	0.055
r7 cell differentiation	GO:0045466	43	0.054
germarium derived female germ line cyst formation	GO:0030727	42	0.054
respiratory system development	GO:0060541	213	0.053
axis specification	GO:0009798	167	0.053
multi organism behavior	GO:0051705	175	0.052
cell migration	GO:0016477	238	0.051
cilium assembly	GO:0042384	38	0.050
reproductive behavior	GO:0019098	122	0.049
regulation of compound eye cone cell fate specification	GO:0042682	4	0.049
protein localization	GO:0008104	284	0.048	Human
cellular protein modification process	GO:0006464	438	0.045
regulation of protein complex assembly	GO:0043254	42	0.045
pigmentation	GO:0043473	75	0.045
exocrine system development	GO:0035272	162	0.044
anterior posterior pattern specification	GO:0009952	136	0.044
dorsal closure	GO:0007391	79	0.041
cilium organization	GO:0044782	41	0.041
positive regulation of gene expression	GO:0010628	290	0.041
regulation of growth	GO:0040008	233	0.040
regulation of anatomical structure size	GO:0090066	163	0.040
learning or memory	GO:0007611	141	0.040
compound eye development	GO:0048749	307	0.039
microtubule bundle formation	GO:0001578	27	0.039
meiosis i	GO:0007127	59	0.039
muscle attachment	GO:0016203	36	0.039
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.039	Human Mouse
ameboidal type cell migration	GO:0001667	151	0.039
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.038
regulation of cell differentiation	GO:0045595	302	0.038
spermatid differentiation	GO:0048515	114	0.037
cytoplasm organization	GO:0007028	64	0.037
regulation of mitotic cell cycle phase transition	GO:1901990	130	0.037
eye photoreceptor cell development	GO:0042462	81	0.037
nucleobase containing compound catabolic process	GO:0034655	165	0.036
endocytic recycling	GO:0032456	13	0.036
molting cycle chitin based cuticle	GO:0007591	56	0.035
developmental maturation	GO:0021700	172	0.035
rna localization	GO:0006403	115	0.034
chromatin silencing	GO:0006342	76	0.034
morphogenesis of an epithelium	GO:0002009	276	0.034
sister chromatid segregation	GO:0000819	92	0.033
pole plasm mrna localization	GO:0019094	49	0.033
positive regulation of signal transduction	GO:0009967	223	0.033
muscle structure development	GO:0061061	224	0.033
regulation of organ morphogenesis	GO:2000027	78	0.033
anterior posterior axis specification embryo	GO:0008595	103	0.033
multi multicellular organism process	GO:0044706	123	0.032
larval development	GO:0002164	104	0.032
chaeta development	GO:0022416	97	0.032
growth	GO:0040007	359	0.031
wnt signaling pathway	GO:0016055	98	0.031
regulation of localization	GO:0032879	275	0.031
ovarian follicle cell development	GO:0030707	248	0.031
embryonic development via the syncytial blastoderm	GO:0001700	148	0.030
negative regulation of rna metabolic process	GO:0051253	251	0.030	Human Mouse
spermatogenesis	GO:0007283	200	0.030
gland morphogenesis	GO:0022612	145	0.030
protein modification process	GO:0036211	438	0.030
tissue migration	GO:0090130	155	0.030
negative regulation of translation	GO:0017148	28	0.029
compound eye photoreceptor cell differentiation	GO:0001751	140	0.029
developmental growth	GO:0048589	280	0.029
single organism biosynthetic process	GO:0044711	206	0.029
multicellular organism growth	GO:0035264	46	0.029
membrane organization	GO:0061024	112	0.028
establishment of localization in cell	GO:0051649	402	0.028
neuron projection guidance	GO:0097485	241	0.028
negative regulation of mitotic cell cycle phase transition	GO:1901991	103	0.028
regulation of cell morphogenesis	GO:0022604	163	0.028
transcription from rna polymerase ii promoter	GO:0006366	368	0.028
regulation of circadian sleep wake cycle sleep	GO:0045187	21	0.028
gene silencing	GO:0016458	138	0.026
multi organism reproductive behavior	GO:0044705	121	0.026
peptidyl amino acid modification	GO:0018193	105	0.026
negative regulation of gene expression epigenetic	GO:0045814	77	0.026
rhythmic behavior	GO:0007622	76	0.025
cellularization	GO:0007349	90	0.025
mitotic g2 m transition checkpoint	GO:0044818	70	0.025
cellular macromolecule localization	GO:0070727	220	0.025	Human
morphogenesis of embryonic epithelium	GO:0016331	94	0.025
purine ribonucleoside triphosphate metabolic process	GO:0009205	119	0.025
regulation of protein polymerization	GO:0032271	28	0.025
protein polymerization	GO:0051258	42	0.025
photoreceptor cell differentiation	GO:0046530	170	0.024
regulation of cell development	GO:0060284	215	0.024
rhythmic process	GO:0048511	106	0.024
pigment metabolic process	GO:0042440	84	0.024
feeding behavior	GO:0007631	50	0.024
gland development	GO:0048732	191	0.023
cell maturation	GO:0048469	144	0.023
developmental programmed cell death	GO:0010623	138	0.023
maintenance of location in cell	GO:0051651	28	0.022	Human
cellular ketone metabolic process	GO:0042180	24	0.022
regulation of programmed cell death	GO:0043067	152	0.022
neurological system process	GO:0050877	358	0.022
tissue morphogenesis	GO:0048729	297	0.022
negative regulation of nervous system development	GO:0051961	92	0.021
organelle fission	GO:0048285	340	0.021
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.021
regulation of reproductive process	GO:2000241	54	0.021
cellular macromolecular complex assembly	GO:0034622	153	0.021
gliogenesis	GO:0042063	80	0.021
melanotic encapsulation of foreign target	GO:0035011	30	0.020
regulation of epithelial cell differentiation	GO:0030856	4	0.020
positive regulation of response to stimulus	GO:0048584	323	0.020
positive regulation of transcription from rna polymerase ii promoter	GO:0045944	204	0.019
actin cytoskeleton organization	GO:0030036	206	0.019
cuticle development	GO:0042335	86	0.019
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.019
hindbrain development	GO:0030902	2	0.019
brain morphogenesis	GO:0048854	16	0.019
cellular catabolic process	GO:0044248	372	0.018
cellular response to chemical stimulus	GO:0070887	199	0.018
meiotic cell cycle	GO:0051321	171	0.018
negative regulation of cell differentiation	GO:0045596	143	0.018
female germ line cyst formation	GO:0048135	42	0.018
axon guidance	GO:0007411	233	0.017
regulation of catabolic process	GO:0009894	170	0.017
epithelial cell migration	GO:0010631	148	0.017
muscle organ development	GO:0007517	127	0.017
eye photoreceptor cell differentiation	GO:0001754	145	0.017
morphogenesis of a polarized epithelium	GO:0001738	93	0.017
phosphorylation	GO:0016310	294	0.017
biological adhesion	GO:0022610	138	0.017
adult behavior	GO:0030534	137	0.017
organic substance transport	GO:0071702	257	0.016
organic substance catabolic process	GO:1901575	308	0.016
innate immune response	GO:0045087	144	0.016
negative regulation of developmental process	GO:0051093	201	0.016
meiotic chromosome segregation	GO:0045132	59	0.016
actin filament polymerization	GO:0030041	27	0.016
musculoskeletal movement	GO:0050881	3	0.016
r1 r6 cell differentiation	GO:0048052	4	0.016
tissue death	GO:0016271	102	0.016
single organism intracellular transport	GO:1902582	207	0.015
rho protein signal transduction	GO:0007266	14	0.015
regulation of molecular function	GO:0065009	217	0.015	Human Mouse
regulation of adult chitin containing cuticle pigmentation	GO:0048082	13	0.015
eggshell formation	GO:0030703	105	0.015
sperm individualization	GO:0007291	48	0.015
enzyme linked receptor protein signaling pathway	GO:0007167	179	0.015
pole plasm oskar mrna localization	GO:0045451	46	0.015
protein complex biogenesis	GO:0070271	201	0.015
germ line cyst formation	GO:0048134	44	0.015
nucleus localization	GO:0051647	34	0.015
cellular response to oxygen containing compound	GO:1901701	79	0.015
regulation of multicellular organismal development	GO:2000026	414	0.015
spinal cord development	GO:0021510	1	0.015
nucleoside metabolic process	GO:0009116	127	0.014
regulation of cytoskeleton organization	GO:0051493	89	0.014
purine containing compound catabolic process	GO:0072523	112	0.014
purine nucleotide metabolic process	GO:0006163	146	0.014
encapsulation of foreign target	GO:0035010	38	0.014
regulation of dna replication	GO:0006275	13	0.014
oocyte anterior posterior axis specification	GO:0007314	72	0.014
localization of cell	GO:0051674	257	0.013
endomembrane system organization	GO:0010256	119	0.013
protein phosphorylation	GO:0006468	169	0.013
gravitaxis	GO:0042332	26	0.013
head development	GO:0060322	135	0.013
mitotic dna integrity checkpoint	GO:0044774	75	0.013
chromosome segregation	GO:0007059	157	0.013
regulation of cellular component biogenesis	GO:0044087	201	0.013
compound eye photoreceptor development	GO:0042051	78	0.013
molting cycle	GO:0042303	56	0.013
regulation of protein modification process	GO:0031399	112	0.013
regulation of g1 s transition of mitotic cell cycle	GO:2000045	23	0.013
mitotic cell cycle phase transition	GO:0044772	138	0.012
single organism cellular localization	GO:1902580	180	0.012
camera type eye development	GO:0043010	4	0.012
heterocycle catabolic process	GO:0046700	166	0.012
negative regulation of cellular protein metabolic process	GO:0032269	85	0.012
morphogenesis of follicular epithelium	GO:0016333	36	0.012
intracellular protein transport	GO:0006886	104	0.012
regulation of cellular catabolic process	GO:0031329	157	0.012
mitotic dna damage checkpoint	GO:0044773	74	0.012
regulation of embryonic cell shape	GO:0016476	30	0.012
long term memory	GO:0007616	62	0.012
mitotic sister chromatid segregation	GO:0000070	87	0.012
organophosphate catabolic process	GO:0046434	112	0.012
positive regulation of catalytic activity	GO:0043085	118	0.012
regulation of embryonic development	GO:0045995	68	0.012
developmental growth involved in morphogenesis	GO:0060560	65	0.011
regulation of organelle organization	GO:0033043	196	0.011
syncytial blastoderm mitotic cell cycle	GO:0035186	21	0.011
establishment or maintenance of epithelial cell apical basal polarity	GO:0045197	24	0.011
cell cycle phase transition	GO:0044770	140	0.011
regulation of cellular component size	GO:0032535	98	0.011
regulation of hemocyte proliferation	GO:0035206	37	0.011
epithelium migration	GO:0090132	148	0.011
macromolecular complex assembly	GO:0065003	256	0.011
intracellular mrna localization	GO:0008298	66	0.011
establishment of nucleus localization	GO:0040023	26	0.011
response to oxygen levels	GO:0070482	59	0.011
circadian rhythm	GO:0007623	105	0.011
dna metabolic process	GO:0006259	227	0.011
positive regulation of cellular protein metabolic process	GO:0032270	118	0.011
regulation of cell death	GO:0010941	173	0.011
regulation of actin filament length	GO:0030832	27	0.010
proteolysis	GO:0006508	192	0.010
regulation of hydrolase activity	GO:0051336	97	0.010
negative regulation of mitotic cell cycle	GO:0045930	109	0.010
defense response	GO:0006952	300	0.010
maintenance of location	GO:0051235	73	0.010	Human
protein targeting	GO:0006605	64	0.010
phenol containing compound metabolic process	GO:0018958	57	0.010
cytoplasmic transport	GO:0016482	130	0.010
intracellular transport	GO:0046907	228	0.010

bip2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

	Disease	DO term ID	Size	Probability	Func Analog Org
	disease of anatomical entity	DOID:7	0	0.019
	disease of cellular proliferation	DOID:14566	0	0.015

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