IMP: Integrative Multi-species Prediction

Drosophila melanogaster

12 known processes

Cyp9f2 (Dmel_CG11466)

CG11466 gene product from transcript CG11466-RB

(Aliases: Cyp 9f2,anon-EST:Posey150,Dmel\CG11466,9f2,CG11466)

Entrez: 41520
FLYBASE: FBgn0038037
UniProtKB: Q9VG82

Process Predictions
Disease Predictions

Cyp9f2 biological process predictions

Show only novel predictionsHighlight processes of functional analogs

Filter by process size:

Biological process	GO term ID	Process size	Probability	Func Analog Org
polyol biosynthetic process	GO:0046173	3	0.791	Human
growth	GO:0040007	359	0.683	Fly
cellular catabolic process	GO:0044248	372	0.648	Human Fly
insecticide metabolic process	GO:0017143	2	0.603	Fly
cellular lipid metabolic process	GO:0044255	83	0.549	Human Fly
secondary metabolite catabolic process	GO:0090487	1	0.507	Fly
sensory perception of chemical stimulus	GO:0007606	116	0.496	Fly
catabolic process	GO:0009056	409	0.378	Human Fly
response to xenobiotic stimulus	GO:0009410	5	0.369	Zebrafish Fly
response to mercury ion	GO:0046689	3	0.364	Fly
small molecule metabolic process	GO:0044281	305	0.357	Human Fly
steroid catabolic process	GO:0006706	1	0.343	Human
lipid catabolic process	GO:0016042	21	0.335	Human
response to organic cyclic compound	GO:0014070	89	0.318	Rat Fly
response to toxic substance	GO:0009636	22	0.309	Fly
cellular hormone metabolic process	GO:0034754	23	0.299	Fly
hormone metabolic process	GO:0042445	33	0.260	Fly
regulation of developmental growth	GO:0048638	174	0.254	Fly
lipid metabolic process	GO:0006629	121	0.247	Human Fly
gland development	GO:0048732	191	0.235
organic hydroxy compound metabolic process	GO:1901615	83	0.207	Human Fly
response to insecticide	GO:0017085	14	0.200	Fly
response to organic substance	GO:0010033	284	0.198	Rat Fly
monocarboxylic acid metabolic process	GO:0032787	29	0.192	Fly
xenobiotic catabolic process	GO:0042178	1	0.182	Fly
regulation of growth	GO:0040008	233	0.175	Fly
organic substance catabolic process	GO:1901575	308	0.173	Human
ketone biosynthetic process	GO:0042181	16	0.165	Fly
chaeta development	GO:0022416	97	0.163
developmental growth	GO:0048589	280	0.162	Fly
androgen metabolic process	GO:0008209	1	0.153
response to organonitrogen compound	GO:0010243	75	0.140	Fly
medium chain fatty acid metabolic process	GO:0051791	1	0.137	Fly
multi organism behavior	GO:0051705	175	0.133	Fly
lipid biosynthetic process	GO:0008610	46	0.133	Human Fly
response to endogenous stimulus	GO:0009719	119	0.125	Rat Fly
death	GO:0016265	284	0.115
response to nitrogen compound	GO:1901698	90	0.113	Fly
tergite morphogenesis	GO:0007490	1	0.110
cellular ketone metabolic process	GO:0042180	24	0.108	Fly
carboxylic acid metabolic process	GO:0019752	92	0.101	Fly
regulation of hormone levels	GO:0010817	40	0.097	Fly
central nervous system development	GO:0007417	201	0.096
positive regulation of multicellular organismal process	GO:0051240	143	0.096	Rat
response to oxygen containing compound	GO:1901700	200	0.092
organonitrogen compound metabolic process	GO:1901564	318	0.089	Human
sterol metabolic process	GO:0016125	12	0.088	Fly
response to temperature stimulus	GO:0009266	106	0.088	Fly
sensory perception	GO:0007600	196	0.087	Fly
organic acid metabolic process	GO:0006082	103	0.084	Fly
response to inorganic substance	GO:0010035	44	0.079	Rat Fly
response to abiotic stimulus	GO:0009628	341	0.078	Fly
epithelial cell development	GO:0002064	274	0.078
single organism catabolic process	GO:0044712	228	0.077	Human Fly
alcohol biosynthetic process	GO:0046165	14	0.074	Human Fly
vitamin metabolic process	GO:0006766	2	0.073	Human
hormone biosynthetic process	GO:0042446	20	0.071	Fly
response to drug	GO:0042493	17	0.070	Human Rat
epithelial cell differentiation	GO:0030855	322	0.068
response to nutrient levels	GO:0031667	114	0.068	Rat
insecticide catabolic process	GO:0046701	1	0.066	Fly
organic cyclic compound catabolic process	GO:1901361	168	0.066	Human
ameboidal type cell migration	GO:0001667	151	0.061
oxidation reduction process	GO:0055114	123	0.060	Human Mouse Rat Fly
cell death	GO:0008219	279	0.059
organonitrogen compound catabolic process	GO:1901565	128	0.058	Human
cellular nitrogen compound catabolic process	GO:0044270	165	0.054	Human
response to hormone	GO:0009725	45	0.054	Rat
histoblast morphogenesis	GO:0007488	9	0.051
organic hydroxy compound biosynthetic process	GO:1901617	21	0.051	Human Fly
programmed cell death	GO:0012501	257	0.047
embryonic morphogenesis	GO:0048598	206	0.046
embryo development ending in birth or egg hatching	GO:0009792	152	0.045
vesicle mediated transport	GO:0016192	381	0.044
ovarian follicle cell migration	GO:0007297	121	0.044
single organism behavior	GO:0044708	391	0.044	Fly
salivary gland morphogenesis	GO:0007435	145	0.044
response to monosaccharide	GO:0034284	4	0.043
cellular amino acid metabolic process	GO:0006520	61	0.042
protein complex assembly	GO:0006461	200	0.041
intracellular signal transduction	GO:0035556	300	0.041
steroid metabolic process	GO:0008202	20	0.040	Human Fly
cellular response to endogenous stimulus	GO:0071495	80	0.040
embryonic development via the syncytial blastoderm	GO:0001700	148	0.039
cell proliferation	GO:0008283	299	0.038
estrogen metabolic process	GO:0008210	1	0.038
positive regulation of signal transduction	GO:0009967	223	0.037
oxoacid metabolic process	GO:0043436	103	0.037	Fly
xenobiotic metabolic process	GO:0006805	5	0.037	Fly
neurological system process	GO:0050877	358	0.036	Fly
columnar cuboidal epithelial cell differentiation	GO:0002065	256	0.035
macromolecular complex assembly	GO:0065003	256	0.035
lauric acid metabolic process	GO:0048252	1	0.034	Fly
cellular response to chemical stimulus	GO:0070887	199	0.034	Fly
positive regulation of response to stimulus	GO:0048584	323	0.033
hormone catabolic process	GO:0042447	3	0.033
response to ethanol	GO:0045471	59	0.033
ecdysone metabolic process	GO:0008205	11	0.032	Fly
response to transition metal nanoparticle	GO:1990267	9	0.032	Fly
single organism biosynthetic process	GO:0044711	206	0.032	Human Fly
wing disc morphogenesis	GO:0007472	344	0.032
ion homeostasis	GO:0050801	55	0.031	Rat
heterocycle catabolic process	GO:0046700	166	0.031
brain development	GO:0007420	120	0.031
single organism carbohydrate metabolic process	GO:0044723	72	0.031
pattern recognition receptor signaling pathway	GO:0002221	2	0.031
response to caffeine	GO:0031000	12	0.030	Fly
response to extracellular stimulus	GO:0009991	116	0.030	Rat
aromatic compound catabolic process	GO:0019439	166	0.029
sensory perception of smell	GO:0007608	80	0.029	Fly
alcohol metabolic process	GO:0006066	25	0.029	Human Fly
positive regulation of signaling	GO:0023056	243	0.029
ovarian follicle cell development	GO:0030707	248	0.029
dorsal closure	GO:0007391	79	0.029
glycerolipid catabolic process	GO:0046503	3	0.029
response to acid chemical	GO:0001101	25	0.028
organophosphate catabolic process	GO:0046434	112	0.028
morphogenesis of an epithelium	GO:0002009	276	0.028
apoptotic process	GO:0006915	159	0.028
sulfur compound metabolic process	GO:0006790	59	0.027
digestive system development	GO:0055123	149	0.027
response to alkaloid	GO:0043279	26	0.026	Fly
digestive tract development	GO:0048565	149	0.026
forebrain development	GO:0030900	2	0.026
aging	GO:0007568	143	0.025	Rat
gland morphogenesis	GO:0022612	145	0.025
positive regulation of developmental process	GO:0051094	143	0.025
acylglycerol biosynthetic process	GO:0046463	2	0.025
ecdysone biosynthetic process	GO:0006697	9	0.025	Fly
positive regulation of macromolecule metabolic process	GO:0010604	405	0.024	Mouse
positive regulation of gene expression	GO:0010628	290	0.024	Mouse
endocytosis	GO:0006897	310	0.024
cellular response to abiotic stimulus	GO:0071214	58	0.024
regulation of cellular ketone metabolic process	GO:0010565	3	0.024
phagocytosis	GO:0006909	215	0.023
carbohydrate derivative metabolic process	GO:1901135	217	0.023
response to alcohol	GO:0097305	95	0.023
morphogenesis of embryonic epithelium	GO:0016331	94	0.022
response to copper ion	GO:0046688	4	0.022
chemical homeostasis	GO:0048878	92	0.022	Rat
appendage development	GO:0048736	401	0.022
protein modification process	GO:0036211	438	0.022
chemosensory behavior	GO:0007635	106	0.022
cellular modified amino acid metabolic process	GO:0006575	45	0.022
positive regulation of growth	GO:0045927	75	0.022
positive regulation of developmental growth	GO:0048639	62	0.022
salivary gland cell autophagic cell death	GO:0035071	83	0.021
telencephalon development	GO:0021537	2	0.021
ecdysteroid metabolic process	GO:0045455	19	0.021	Fly
ethanolamine containing compound metabolic process	GO:0042439	4	0.020
response to hexose	GO:0009746	3	0.020
imaginal disc derived wing morphogenesis	GO:0007476	337	0.020
lipid storage	GO:0019915	38	0.020
positive regulation of cell migration	GO:0030335	2	0.019
response to carbohydrate	GO:0009743	15	0.019
immune system development	GO:0002520	57	0.019
defense response to gram negative bacterium	GO:0050829	94	0.019	Fly
cell motility	GO:0048870	251	0.019
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.019
steroid biosynthetic process	GO:0006694	16	0.019	Human Fly
response to peptide hormone	GO:0043434	29	0.019
chitin based cuticle development	GO:0040003	49	0.018
salivary gland histolysis	GO:0035070	88	0.018
positive regulation of cell motility	GO:2000147	3	0.018
fat soluble vitamin biosynthetic process	GO:0042362	1	0.018	Human
lateral inhibition	GO:0046331	206	0.018
cellular protein modification process	GO:0006464	438	0.018
tissue migration	GO:0090130	155	0.017
neutral lipid catabolic process	GO:0046461	3	0.017
small molecule biosynthetic process	GO:0044283	37	0.017	Human Fly
glycoprotein metabolic process	GO:0009100	41	0.017
regulation of transport	GO:0051049	181	0.016
response to lipopolysaccharide	GO:0032496	4	0.016
camera type eye development	GO:0043010	4	0.016
kidney development	GO:0001822	3	0.016
protein complex biogenesis	GO:0070271	201	0.016
response to glucose	GO:0009749	2	0.016
actin filament organization	GO:0007015	126	0.016
homeostatic process	GO:0042592	199	0.016	Rat
regulation of localization	GO:0032879	275	0.016
aggressive behavior	GO:0002118	63	0.016	Fly
response to lipid	GO:0033993	38	0.015	Rat
response to other organism	GO:0051707	293	0.015	Fly
cellular lipid catabolic process	GO:0044242	16	0.015
columnar cuboidal epithelial cell development	GO:0002066	249	0.015
post embryonic appendage morphogenesis	GO:0035120	385	0.015
tissue death	GO:0016271	102	0.015
cellular response to ethanol	GO:0071361	4	0.015
cellular response to hormone stimulus	GO:0032870	44	0.015
organophosphate metabolic process	GO:0019637	195	0.015
reproductive system development	GO:0061458	74	0.015
circadian rhythm	GO:0007623	105	0.015
response to peptide	GO:1901652	29	0.015
isoprenoid metabolic process	GO:0006720	8	0.015	Human
positive regulation of phosphate metabolic process	GO:0045937	139	0.015
cuticle development	GO:0042335	86	0.014
mrna metabolic process	GO:0016071	124	0.014
regulation of mrna metabolic process	GO:1903311	72	0.014
cell migration	GO:0016477	238	0.014
positive regulation of multicellular organism growth	GO:0040018	21	0.014
response to radiation	GO:0009314	155	0.014
response to starvation	GO:0042594	97	0.014
rna processing	GO:0006396	147	0.014
response to biotic stimulus	GO:0009607	294	0.014	Fly
carbohydrate derivative biosynthetic process	GO:1901137	85	0.014
regulation of response to stress	GO:0080134	200	0.014
regulation of lipid transport	GO:0032368	3	0.014
retina development in camera type eye	GO:0060041	4	0.014
regulation of intracellular signal transduction	GO:1902531	236	0.014
cellular amine metabolic process	GO:0044106	12	0.013
response to metal ion	GO:0010038	23	0.013	Rat Fly
ecdysteroid biosynthetic process	GO:0045456	15	0.013	Fly
cation transport	GO:0006812	110	0.013
histolysis	GO:0007559	102	0.013
salivary gland development	GO:0007431	162	0.013
midgut development	GO:0007494	23	0.013
positive regulation of cell communication	GO:0010647	250	0.013
synapse assembly	GO:0007416	143	0.013
head development	GO:0060322	135	0.013
regulation of mrna processing	GO:0050684	71	0.013
developmental programmed cell death	GO:0010623	138	0.013
triglyceride biosynthetic process	GO:0019432	2	0.012
regulation of rna splicing	GO:0043484	69	0.012
carbohydrate metabolic process	GO:0005975	82	0.012
tube development	GO:0035295	244	0.012
regulation of hemocyte proliferation	GO:0035206	37	0.012
sulfur compound biosynthetic process	GO:0044272	16	0.012
fatty acid metabolic process	GO:0006631	20	0.012	Fly
sex differentiation	GO:0007548	81	0.012
hematopoietic or lymphoid organ development	GO:0048534	57	0.012
connective tissue development	GO:0061448	3	0.012
phosphatidylethanolamine metabolic process	GO:0046337	1	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.012
tissue morphogenesis	GO:0048729	297	0.012
response to organophosphorus	GO:0046683	2	0.011	Fly
regulation of sterol transport	GO:0032371	1	0.011
single organism cellular localization	GO:1902580	180	0.011
border follicle cell migration	GO:0007298	113	0.011
acylglycerol metabolic process	GO:0006639	12	0.011
positive regulation of cellular component biogenesis	GO:0044089	80	0.011
reproductive structure development	GO:0048608	74	0.011
regulation of cell death	GO:0010941	173	0.011
mrna processing	GO:0006397	104	0.011
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.011
terpenoid metabolic process	GO:0006721	7	0.011	Human
response to decreased oxygen levels	GO:0036293	58	0.011
response to bacterium	GO:0009617	198	0.011	Fly
acylglycerol catabolic process	GO:0046464	3	0.011
regulation of anatomical structure size	GO:0090066	163	0.011	Rat
regulation of cholesterol transport	GO:0032374	1	0.011
imaginal disc derived appendage development	GO:0048737	399	0.010
anion homeostasis	GO:0055081	3	0.010	Rat
cellular response to water stimulus	GO:0071462	2	0.010
head involution	GO:0008258	35	0.010
phosphorylation	GO:0016310	294	0.010
cell division	GO:0051301	248	0.010

Cyp9f2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability	Func Analog Org
disease of anatomical entity	DOID:7	0.187	Human
hypertension	DOID:10763	0.127	Human
vascular disease	DOID:178	0.127	Human
artery disease	DOID:0050828	0.127	Human
cardiovascular system disease	DOID:1287	0.127	Human
disease of metabolism	DOID:0014667	0.074
lipid metabolism disorder	DOID:3146	0.074
familial hyperlipidemia	DOID:1168	0.074
familial combined hyperlipidemia	DOID:13809	0.074
inherited metabolic disorder	DOID:655	0.074
familial lipoprotein lipase deficiency	DOID:14118	0.014

Loading network...

Network Filters

Minimum relationship confidence:

Maximum number of genes:

Highlight known relationships in gold.

Graphical Options

Adjust edge length:

Adjust node size:

Fixed layout

Black background

Low confidence color:

Med confidence color:

High confidence color:

Hide the legend in the network