IMP: Integrative Multi-species Prediction

Drosophila melanogaster

0 known processes

lambdaTry (Dmel_CG12350)

CG12350 gene product from transcript CG12350-RA

(Aliases: SP76,CG12350,Dmel\CG12350)

Entrez: 36214
FLYBASE: FBgn0043470
UniProtKB: Q7JPN9

Process Predictions
Disease Predictions

lambdaTry biological process predictions

Show only novel predictionsHighlight processes of functional analogs

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Biological process	GO term ID	Process size	Probability
response to external biotic stimulus	GO:0043207	293	0.058
phagocytosis	GO:0006909	215	0.057
lateral inhibition	GO:0046331	206	0.055
response to other organism	GO:0051707	293	0.038
endocytosis	GO:0006897	310	0.036
organic substance transport	GO:0071702	257	0.033
body morphogenesis	GO:0010171	2	0.033
response to endogenous stimulus	GO:0009719	119	0.031
intracellular signal transduction	GO:0035556	300	0.031
positive regulation of cell communication	GO:0010647	250	0.030
response to biotic stimulus	GO:0009607	294	0.030
protein modification process	GO:0036211	438	0.029
cell cell signaling involved in cell fate commitment	GO:0045168	210	0.028
response to oxygen containing compound	GO:1901700	200	0.028
defense response	GO:0006952	300	0.028
cellular protein modification process	GO:0006464	438	0.027
pattern recognition receptor signaling pathway	GO:0002221	2	0.024
cell proliferation	GO:0008283	299	0.024
immune response regulating signaling pathway	GO:0002764	2	0.024
response to lipopolysaccharide	GO:0032496	4	0.023
rna localization	GO:0006403	115	0.023
response to organonitrogen compound	GO:0010243	75	0.022
response to alcohol	GO:0097305	95	0.022
wing disc morphogenesis	GO:0007472	344	0.022
phosphorylation	GO:0016310	294	0.022
response to abiotic stimulus	GO:0009628	341	0.022
defense response to other organism	GO:0098542	225	0.022
regulation of response to stress	GO:0080134	200	0.022
positive regulation of response to stimulus	GO:0048584	323	0.022
imaginal disc derived wing morphogenesis	GO:0007476	337	0.021
regulation of localization	GO:0032879	275	0.021
activation of innate immune response	GO:0002218	4	0.021
post embryonic appendage morphogenesis	GO:0035120	385	0.021
single organism behavior	GO:0044708	391	0.021
vesicle mediated transport	GO:0016192	381	0.021
negative regulation of signal transduction	GO:0009968	206	0.020
regulation of intracellular signal transduction	GO:1902531	236	0.020
catabolic process	GO:0009056	409	0.020
camera type eye development	GO:0043010	4	0.020
regulation of multicellular organismal development	GO:2000026	414	0.020
developmental growth	GO:0048589	280	0.020
dephosphorylation	GO:0016311	51	0.020
imaginal disc derived appendage development	GO:0048737	399	0.020
localization of cell	GO:0051674	257	0.020
immune response activating signal transduction	GO:0002757	2	0.020
response to organic cyclic compound	GO:0014070	89	0.019
appendage development	GO:0048736	401	0.019
intracellular transport	GO:0046907	228	0.019
immune effector process	GO:0002252	98	0.019
regulation of anatomical structure morphogenesis	GO:0022603	242	0.018
establishment of localization in cell	GO:0051649	402	0.018
appendage morphogenesis	GO:0035107	397	0.018
negative regulation of signaling	GO:0023057	219	0.018
carbohydrate derivative metabolic process	GO:1901135	217	0.018
cellular response to dna damage stimulus	GO:0006974	223	0.018
regulation of immune effector process	GO:0002697	52	0.018
regulation of cell cycle	GO:0051726	291	0.018
small molecule metabolic process	GO:0044281	305	0.018
negative regulation of cell communication	GO:0010648	223	0.018
positive regulation of signaling	GO:0023056	243	0.017
organophosphate metabolic process	GO:0019637	195	0.017
response to nitrogen compound	GO:1901698	90	0.017
response to organic substance	GO:0010033	284	0.017
death	GO:0016265	284	0.017
cellular amine metabolic process	GO:0044106	12	0.017
growth	GO:0040007	359	0.017
single organism catabolic process	GO:0044712	228	0.017
organic acid metabolic process	GO:0006082	103	0.017
organonitrogen compound metabolic process	GO:1901564	318	0.017
regulation of cellular ketone metabolic process	GO:0010565	3	0.016
regulation of transport	GO:0051049	181	0.016
positive regulation of multicellular organismal process	GO:0051240	143	0.016
cell death	GO:0008219	279	0.016
cellular amino acid metabolic process	GO:0006520	61	0.016
positive regulation of intracellular signal transduction	GO:1902533	116	0.015
negative regulation of response to stimulus	GO:0048585	258	0.015
cation transport	GO:0006812	110	0.015
regionalization	GO:0003002	416	0.015
regulation of cellular response to stress	GO:0080135	89	0.015
transcription from rna polymerase ii promoter	GO:0006366	368	0.015
single organism biosynthetic process	GO:0044711	206	0.015
organic substance catabolic process	GO:1901575	308	0.015
negative regulation of gene expression	GO:0010629	387	0.015
nuclear division	GO:0000280	332	0.015
amine metabolic process	GO:0009308	12	0.015
cholesterol transport	GO:0030301	2	0.015
regulation of response to biotic stimulus	GO:0002831	63	0.015
compound eye morphogenesis	GO:0001745	249	0.014
innate immune response activating signal transduction	GO:0002758	2	0.014
nitrogen compound transport	GO:0071705	85	0.014
regulation of cellular amino acid metabolic process	GO:0006521	0	0.014
eye morphogenesis	GO:0048592	260	0.014
segmentation	GO:0035282	207	0.014
proteolysis	GO:0006508	192	0.014
regulation of cellular amine metabolic process	GO:0033238	3	0.014
carboxylic acid metabolic process	GO:0019752	92	0.014
response to bacterium	GO:0009617	198	0.014
establishment of rna localization	GO:0051236	47	0.013
macromolecular complex assembly	GO:0065003	256	0.013
connective tissue development	GO:0061448	3	0.013
imaginal disc derived appendage morphogenesis	GO:0035114	395	0.013
positive regulation of i kappab kinase nf kappab signaling	GO:0043123	1	0.013
single organism intracellular transport	GO:1902582	207	0.013
regulation of cell differentiation	GO:0045595	302	0.013
sensory perception of sound	GO:0007605	56	0.013
negative regulation of cellular metabolic process	GO:0031324	382	0.013
response to radiation	GO:0009314	155	0.013
embryonic pattern specification	GO:0009880	174	0.013
compound eye development	GO:0048749	307	0.013
triglyceride catabolic process	GO:0019433	3	0.013
notch signaling pathway	GO:0007219	120	0.013
cell division	GO:0051301	248	0.013
developmental maturation	GO:0021700	172	0.013
immune response	GO:0006955	246	0.013
kidney development	GO:0001822	3	0.013
positive regulation of nitrogen compound metabolic process	GO:0051173	354	0.013
regulation of cell death	GO:0010941	173	0.013
negative regulation of nitrogen compound metabolic process	GO:0051172	265	0.013
forebrain development	GO:0030900	2	0.013
positive regulation of cellular amine metabolic process	GO:0033240	0	0.013
regulation of phosphorus metabolic process	GO:0051174	210	0.012
positive regulation of signal transduction	GO:0009967	223	0.012
macromolecule catabolic process	GO:0009057	161	0.012
leucine transport	GO:0015820	3	0.012
regulation of i kappab kinase nf kappab signaling	GO:0043122	2	0.012
chemical homeostasis	GO:0048878	92	0.012
positive regulation of transport	GO:0051050	92	0.012
protein complex biogenesis	GO:0070271	201	0.012
regulation of multi organism process	GO:0043900	131	0.012
positive regulation of nucleobase containing compound metabolic process	GO:0045935	332	0.012
organelle fission	GO:0048285	340	0.012
gene silencing	GO:0016458	138	0.012
regulation of transcription from rna polymerase ii promoter	GO:0006357	378	0.012
positive regulation of cellular amino acid metabolic process	GO:0045764	0	0.012
organonitrogen compound biosynthetic process	GO:1901566	117	0.012
dendrite development	GO:0016358	204	0.012
ion transport	GO:0006811	145	0.012
regulation of cellular protein metabolic process	GO:0032268	243	0.012
fluid transport	GO:0042044	19	0.012
cholesterol homeostasis	GO:0042632	3	0.012
regulation of notch signaling pathway	GO:0008593	100	0.012
camera type eye morphogenesis	GO:0048593	2	0.012
regulation of catabolic process	GO:0009894	170	0.011
signal transduction by phosphorylation	GO:0023014	107	0.011
mitotic cell cycle phase transition	GO:0044772	138	0.011
regulation of autophagy	GO:0010506	62	0.011
hindbrain development	GO:0030902	2	0.011
negative regulation of biosynthetic process	GO:0009890	277	0.011
regulation of membrane potential	GO:0042391	35	0.011
cellular catabolic process	GO:0044248	372	0.011
protein localization	GO:0008104	284	0.011
protein complex assembly	GO:0006461	200	0.011
regulation of lipid transport	GO:0032368	3	0.011
regulation of defense response to virus	GO:0050688	14	0.011
axis specification	GO:0009798	167	0.011
regulation of cellular catabolic process	GO:0031329	157	0.011
anterior posterior axis specification	GO:0009948	109	0.011
regulation of protein metabolic process	GO:0051246	256	0.011
cell cycle phase transition	GO:0044770	140	0.011
limb development	GO:0060173	1	0.011
blastoderm segmentation	GO:0007350	159	0.011
multi organism behavior	GO:0051705	175	0.011
response to hexose	GO:0009746	3	0.011
regulation of programmed cell death	GO:0043067	152	0.011
monocarboxylic acid transport	GO:0015718	3	0.011
telencephalon development	GO:0021537	2	0.011
small gtpase mediated signal transduction	GO:0007264	88	0.010
cytoplasmic transport	GO:0016482	130	0.010
cellular homeostasis	GO:0019725	80	0.010
cellular ketone metabolic process	GO:0042180	24	0.010
sterol homeostasis	GO:0055092	4	0.010
regulation of organelle organization	GO:0033043	196	0.010
positive regulation of rna biosynthetic process	GO:1902680	266	0.010
homeostatic process	GO:0042592	199	0.010
positive regulation of cellular biosynthetic process	GO:0031328	316	0.010
anterior posterior pattern specification	GO:0009952	136	0.010
fatty acid elongation	GO:0030497	3	0.010
cell motility	GO:0048870	251	0.010
regulation of molecular function	GO:0065009	217	0.010
nucleobase containing compound transport	GO:0015931	56	0.010
response to organophosphorus	GO:0046683	2	0.010
negative regulation of nucleic acid templated transcription	GO:1903507	240	0.010
long chain fatty acid metabolic process	GO:0001676	3	0.010

lambdaTry disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

Disease	DO term ID	Probability
disease of anatomical entity	DOID:7	0.036
type 2 diabetes mellitus	DOID:9352	0.028
carbohydrate metabolism disease	DOID:0050013	0.028
diabetes mellitus	DOID:9351	0.028
disease of metabolism	DOID:0014667	0.028
acquired metabolic disease	DOID:0060158	0.028
glucose metabolism disease	DOID:4194	0.028
musculoskeletal system disease	DOID:17	0.020
hair disease	DOID:421	0.018
integumentary system disease	DOID:16	0.018
nervous system disease	DOID:863	0.014
connective tissue disease	DOID:65	0.014
inherited metabolic disorder	DOID:655	0.012
bone disease	DOID:0080001	0.011
disease of cellular proliferation	DOID:14566	0.011
sensory system disease	DOID:0050155	0.011

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