Drosophila melanogaster

267 known processes

RhoGEF2 (Dmel_CG9635)

CG9635 gene product from transcript CG9635-RF

(Aliases: dRhoGEF2,shar,DRhoGEF,rhogef2,Rho-GEF2,RhoGEF,RhoGef2,CG9635,T2,dRhoGEF,l(2)04291,rhoGEF2,Gef2,DRhoGEF2,Dmel\CG9635,Su(Rho1)2B,DrhoGEF2)

RhoGEF2 biological process predictions


Filter by process size:
Biological processGO term IDProcess sizeProbabilityFunc Analog Org
cell motilityGO:00488702510.943
nuclear divisionGO:00002803320.911
regulation of cell projection organizationGO:0031344920.906
appendage morphogenesisGO:00351073970.889
catabolic processGO:00090564090.888
regulation of anatomical structure morphogenesisGO:00226032420.880
regulation of cell morphogenesisGO:00226041630.852
regulation of localizationGO:00328792750.844
positive regulation of cellular component organizationGO:00511301560.829
growthGO:00400073590.826
wing disc morphogenesisGO:00074723440.806
epithelial cell developmentGO:00020642740.800
regulation of developmental growthGO:00486381740.689
imaginal disc derived appendage morphogenesisGO:00351143950.636
tube developmentGO:00352952440.635
establishment of localization in cellGO:00516494020.628
nucleobase containing compound catabolic processGO:00346551650.623
post embryonic appendage morphogenesisGO:00351203850.623
regulation of protein polymerizationGO:0032271280.589
tube morphogenesisGO:00352391910.587
protein complex biogenesisGO:00702712010.577
regulation of growthGO:00400082330.545
cognitionGO:00508901410.532
regulation of nervous system developmentGO:00519602480.529
intracellular signal transductionGO:00355563000.527
actin filament based processGO:00300292200.512
regulation of multicellular organismal developmentGO:20000264140.503
cellular catabolic processGO:00442483720.483
immune system processGO:00023763470.457
cellular protein modification processGO:00064644380.454
heterocycle catabolic processGO:00467001660.443
positive regulation of cell projection organizationGO:0031346290.442
imaginal disc derived appendage developmentGO:00487373990.441
macromolecular complex assemblyGO:00650032560.440
regulation of phosphate metabolic processGO:00192202100.424
neuron projection guidanceGO:00974852410.404
appendage developmentGO:00487364010.401
imaginal disc derived wing morphogenesisGO:00074763370.395
cellular component assembly involved in morphogenesisGO:00109271510.392
protein catabolic processGO:00301631010.387
actin cytoskeleton organizationGO:00300362060.384
vesicle mediated transportGO:00161923810.380
regulation of axonogenesisGO:0050770320.351
defense responseGO:00069523000.340
purine ribonucleotide catabolic processGO:00091541090.334
carbohydrate derivative metabolic processGO:19011352170.328
organic cyclic compound catabolic processGO:19013611680.328
positive regulation of rac gtpase activityGO:003285580.321
apoptotic processGO:00069151590.318
cellular macromolecule localizationGO:00707272200.300
cell deathGO:00082192790.292
cellular macromolecule catabolic processGO:00442651360.290
proteolysisGO:00065081920.285
regulation of cell differentiationGO:00455953020.284
cellular protein localizationGO:00346131600.284
homeostatic processGO:00425921990.272
axonogenesisGO:00074092900.261
programmed cell deathGO:00125012570.259
developmental growthGO:00485892800.259
endocytosisGO:00068973100.256
positive regulation of rho gtpase activityGO:0032321190.251
aromatic compound catabolic processGO:00194391660.239
regulation of response to stressGO:00801342000.238
organelle fissionGO:00482853400.237
nucleotide catabolic processGO:00091661090.233
ameboidal type cell migrationGO:00016671510.228
protein complex assemblyGO:00064612000.228
ubiquitin dependent protein catabolic processGO:0006511780.228
embryonic morphogenesisGO:00485982060.225
cell proliferationGO:00082832990.224
macromolecule catabolic processGO:00090571610.223
columnar cuboidal epithelial cell developmentGO:00020662490.222
filopodium assemblyGO:0046847330.217
cell divisionGO:00513012480.210
proteolysis involved in cellular protein catabolic processGO:0051603830.208
protein modification processGO:00362114380.205
positive regulation of response to stimulusGO:00485843230.200
eye developmentGO:00016543230.199
response to extracellular stimulusGO:00099911160.197
cell migrationGO:00164772380.193
positive regulation of gtpase activityGO:0043547430.190
positive regulation of transportGO:0051050920.182
ribonucleoside triphosphate metabolic processGO:00091991190.182
localization of cellGO:00516742570.180
small molecule metabolic processGO:00442813050.175
deathGO:00162652840.171
glycosyl compound metabolic processGO:19016571270.171
digestive tract morphogenesisGO:00485461270.169
regulation of vesicle mediated transportGO:0060627590.169
regulation of catabolic processGO:00098941700.168
nucleoside catabolic processGO:00091641120.168
compound eye developmentGO:00487493070.166
cellular protein catabolic processGO:0044257830.162
epithelial cell differentiationGO:00308553220.161
spindle organizationGO:00070512530.160
guanosine containing compound metabolic processGO:1901068740.156
purine nucleotide metabolic processGO:00061631460.152
purine containing compound catabolic processGO:00725231120.150
regulation of rho protein signal transductionGO:0035023200.148
regulation of neuron differentiationGO:00456641030.146
purine nucleoside metabolic processGO:00422781270.145
meiotic nuclear divisionGO:00071261510.145
endomembrane system organizationGO:00102561190.144
purine nucleoside catabolic processGO:00061521120.142
synapse organizationGO:00508081960.139
organic substance catabolic processGO:19015753080.138
intracellular transportGO:00469072280.138
regulation of neurogenesisGO:00507671580.136
small gtpase mediated signal transductionGO:0007264880.135
spindle assemblyGO:0051225800.132
lipid metabolic processGO:00066291210.132
regulation of molecular functionGO:00650092170.131
taxisGO:00423303040.131
positive regulation of cellular catabolic processGO:0031331950.130
ribonucleoside triphosphate catabolic processGO:00092031080.129
cell type specific apoptotic processGO:0097285380.129
regulation of synapse organizationGO:00508071100.128
regulation of transportGO:00510491810.128
embryonic development via the syncytial blastodermGO:00017001480.125
mitotic nuclear divisionGO:00070672130.122
learning or memoryGO:00076111410.121
regulation of response to external stimulusGO:00321011150.121
cell junction organizationGO:0034330570.120
positive regulation of developmental processGO:00510941430.116
regulation of neuron projection developmentGO:0010975690.115
protein modification by small protein conjugation or removalGO:00706471060.114
organonitrogen compound metabolic processGO:19015643180.113
guanosine containing compound catabolic processGO:1901069740.112
neurological system processGO:00508773580.111
Worm
positive regulation of cellular component biogenesisGO:0044089800.111
cellular nitrogen compound catabolic processGO:00442701650.110
regulation of cell developmentGO:00602842150.110
cellular response to radiationGO:0071478520.109
regulation of cell shapeGO:00083601130.109
chemotaxisGO:00069352490.108
organophosphate metabolic processGO:00196371950.107
regulation of cell morphogenesis involved in differentiationGO:0010769610.105
modification dependent macromolecule catabolic processGO:0043632790.105
intracellular protein transportGO:00068861040.103
purine nucleoside triphosphate metabolic processGO:00091441190.101
ion transportGO:00068111450.100
body morphogenesisGO:001017120.099
cellular protein complex disassemblyGO:0043624350.097
negative regulation of nervous system developmentGO:0051961920.097
negative regulation of response to stimulusGO:00485852580.097
cytoplasmic transportGO:00164821300.096
single organism behaviorGO:00447083910.093
Worm
regulation of cellular component movementGO:0051270420.092
actin filament polymerizationGO:0030041270.092
developmental programmed cell deathGO:00106231380.091
dna metabolic processGO:00062592270.087
biological adhesionGO:00226101380.086
adherens junction organizationGO:0034332270.085
oocyte developmentGO:00485991240.085
organic substance transportGO:00717022570.084
sarcomere organizationGO:0045214260.084
dna repairGO:0006281540.082
regulation of actin filament polymerizationGO:0030833250.082
protein localization to plasma membraneGO:0072659130.082
apoptotic signaling pathwayGO:0097190270.081
maintenance of locationGO:0051235730.081
regulation of immune responseGO:00507761180.081
nucleoside triphosphate metabolic processGO:00091411200.081
negative regulation of cytoskeleton organizationGO:0051494300.081
positive regulation of cell developmentGO:0010720610.079
regulation of cellular protein metabolic processGO:00322682430.079
positive regulation of molecular functionGO:00440931360.079
regulation of cell proliferationGO:00421271630.079
regulation of intracellular signal transductionGO:19025312360.078
protein modification by small protein conjugationGO:0032446790.076
glycosyl compound catabolic processGO:19016581120.076
forebrain developmentGO:003090020.075
morphogenesis of embryonic epitheliumGO:0016331940.074
cellular response to ionizing radiationGO:0071479150.073
purine ribonucleotide metabolic processGO:00091501450.072
regulation of cell deathGO:00109411730.071
dendrite developmentGO:00163582040.069
rho protein signal transductionGO:0007266140.069
positive regulation of phosphate metabolic processGO:00459371390.069
reproductive structure developmentGO:0048608740.066
cell projection assemblyGO:0030031940.065
negative regulation of signal transductionGO:00099682060.065
dephosphorylationGO:0016311510.065
axon developmentGO:00615642970.065
positive regulation of catabolic processGO:00098961050.064
positive regulation of cellular protein metabolic processGO:00322701180.063
purine nucleotide catabolic processGO:00061951090.063
meiotic cell cycleGO:00513211710.062
digestive system developmentGO:00551231490.062
regulation of filopodium assemblyGO:0051489240.060
purine ribonucleoside catabolic processGO:00461301120.059
protein phosphorylationGO:00064681690.059
regulation of actin filament lengthGO:0030832270.059
regulation of cellular component sizeGO:0032535980.058
regulation of notch signaling pathwayGO:00085931000.058
gland morphogenesisGO:00226121450.057
regulation of immune system processGO:00026821760.057
cellular response to chemical stimulusGO:00708871990.057
mushroom body developmentGO:0016319700.057
cellular amino acid metabolic processGO:0006520610.056
single organism intracellular transportGO:19025822070.056
phosphorylationGO:00163102940.055
lamellipodium organizationGO:0097581210.055
morphogenesis of an epitheliumGO:00020092760.054
activation of ras gtpase activityGO:003285660.054
central nervous system developmentGO:00074172010.053
regulation of cell substrate adhesionGO:001081020.053
purine ribonucleoside triphosphate catabolic processGO:00092071080.052
regulation of cell sizeGO:0008361630.051
regulation of actin polymerization or depolymerizationGO:0008064270.051
embryo development ending in birth or egg hatchingGO:00097921520.051
tissue morphogenesisGO:00487292970.051
neuron recognitionGO:00080381010.050
response to organic substanceGO:00100332840.050
protein complex disassemblyGO:0043241360.050
nucleoside phosphate catabolic processGO:19012921100.050
cell growthGO:00160491080.049
response to woundingGO:0009611940.049
regulation of organ morphogenesisGO:2000027780.049
digestive tract developmentGO:00485651490.048
positive regulation of multicellular organismal processGO:00512401430.048
regulation of ras protein signal transductionGO:0046578930.048
protein ubiquitinationGO:0016567700.047
golgi localizationGO:005164520.047
phagocytosisGO:00069092150.047
female meiotic divisionGO:0007143700.046
olfactory behaviorGO:0042048970.046
axon guidanceGO:00074112330.045
cell cell junction organizationGO:0045216550.045
ribonucleoside metabolic processGO:00091191270.045
cell cell junction assemblyGO:0007043380.045
establishment or maintenance of cell polarityGO:00071631670.045
oxoacid metabolic processGO:00434361030.044
tissue migrationGO:00901301550.044
protein localizationGO:00081042840.044
delaminationGO:006023280.043
head developmentGO:00603221350.043
regulation of catalytic activityGO:00507901850.043
negative regulation of cell communicationGO:00106482230.042
sensory perceptionGO:00076001960.042
Worm
telencephalon developmentGO:002153720.042
negative regulation of signalingGO:00230572190.042
regulation of phosphatidylinositol 3 kinase activityGO:004355120.042
cellular component disassemblyGO:0022411460.042
positive regulation of protein metabolic processGO:00512471280.041
immune responseGO:00069552460.041
cell adhesionGO:00071551360.041
single organism membrane organizationGO:0044802930.041
compound eye photoreceptor cell differentiationGO:00017511400.040
regulation of protein metabolic processGO:00512462560.040
cortical actin cytoskeleton organizationGO:0030866240.040
regulation of rho gtpase activityGO:0032319200.039
ribonucleoside catabolic processGO:00424541120.039
nuclear transcribed mrna poly a tail shorteningGO:0000289120.039
neural precursor cell proliferationGO:0061351750.039
regulation of response to woundingGO:1903034190.039
nucleoside metabolic processGO:00091161270.038
single organism catabolic processGO:00447122280.038
regulation of actin filament based processGO:0032970420.038
Zebrafish
cell competition in a multicellular organismGO:0035212100.038
post golgi vesicle mediated transportGO:0006892110.038
germ band extensionGO:0007377110.037
stem cell divisionGO:0017145690.037
regulation of cellular catabolic processGO:00313291570.037
gastrulationGO:0007369700.036
ribonucleotide metabolic processGO:00092591450.035
inositol lipid mediated signalingGO:004801740.035
protein localization to membraneGO:0072657190.035
regulation of actin cytoskeleton organizationGO:0032956420.035
Zebrafish
rubidium ion transportGO:003582610.035
synapse assemblyGO:00074161430.035
sensory perception of mechanical stimulusGO:0050954720.034
Worm
positive regulation of apoptotic cell clearanceGO:200042720.034
regulation of gtp catabolic processGO:0033124440.034
proteasomal protein catabolic processGO:0010498590.034
germarium derived egg chamber formationGO:00072931010.033
cellular protein complex assemblyGO:0043623710.033
single organism cellular localizationGO:19025801800.033
ovarian follicle cell developmentGO:00307072480.033
regulation of nucleoside metabolic processGO:0009118500.032
regulation of phosphorus metabolic processGO:00511742100.032
anatomical structure homeostasisGO:0060249970.032
mapk cascadeGO:00001651070.032
positive regulation of gtp catabolic processGO:0033126430.031
membrane organizationGO:00610241120.031
axon extensionGO:0048675320.031
eye morphogenesisGO:00485922600.031
regulation of protein complex disassemblyGO:0043244290.031
regulation of cell matrix adhesionGO:000195210.030
purine ribonucleoside triphosphate metabolic processGO:00092051190.030
regulation of programmed cell deathGO:00430671520.030
cellularizationGO:0007349900.029
mesoderm developmentGO:0007498780.029
response to nutrient levelsGO:00316671140.029
regulation of nucleotide catabolic processGO:0030811480.029
response to light stimulusGO:00094161240.028
nucleoside triphosphate catabolic processGO:00091431080.028
cellular homeostasisGO:0019725800.028
negative regulation of neuron deathGO:1901215180.028
positive regulation of cytoskeleton organizationGO:0051495210.028
actin filament bundle assemblyGO:0051017260.028
Zebrafish
regulation of cell projection assemblyGO:0060491300.028
planar cell polarity pathway involved in axis elongationGO:000340230.028
signal transduction by phosphorylationGO:00230141070.028
immune system developmentGO:0002520570.028
lamellipodium assemblyGO:0030032210.027
positive regulation of nucleotide catabolic processGO:0030813460.027
regulation of proteolysisGO:0030162870.027
dendrite morphogenesisGO:00488131990.027
response to abiotic stimulusGO:00096283410.027
Worm
regulation of gtpase activityGO:0043087440.026
modification dependent protein catabolic processGO:0019941780.026
organelle localizationGO:00516401480.026
protein transportGO:00150311550.026
cellular lipid metabolic processGO:0044255830.026
ribose phosphate metabolic processGO:00196931450.025
positive regulation of catalytic activityGO:00430851180.025
mesoderm morphogenesisGO:0048332220.025
positive regulation of cell morphogenesis involved in differentiationGO:0010770120.025
phototransductionGO:0007602520.025
notch signaling pathwayGO:00072191200.025
regulation of purine nucleotide catabolic processGO:0033121480.025
innate immune responseGO:00450871440.025
regulation of transcription from rna polymerase ii promoterGO:00063573780.024
regulation of defense responseGO:00313471020.024
positive regulation of cell deathGO:0010942690.024
morphogenesis of a polarized epitheliumGO:0001738930.024
jnk cascadeGO:0007254500.024
exocrine system developmentGO:00352721620.024
regulation of cellular component biogenesisGO:00440872010.024
epithelial cell migrationGO:00106311480.024
compound eye morphogenesisGO:00017452490.023
organic acid metabolic processGO:00060821030.023
nucleotide metabolic processGO:00091171610.023
phosphatidylinositol mediated signalingGO:004801540.023
golgi vesicle transportGO:0048193270.023
lipid localizationGO:0010876540.023
cell junction assemblyGO:0034329420.023
ribonucleotide catabolic processGO:00092611090.022
regulation of hydrolase activityGO:0051336970.022
regulation of locomotionGO:0040012420.022
epithelial tube morphogenesisGO:0060562880.022
positive regulation of ras gtpase activityGO:0032320360.022
regulation of endocytosisGO:0030100370.022
immune effector processGO:0002252980.021
negative regulation of neuron apoptotic processGO:0043524140.021
positive regulation of phosphorus metabolic processGO:00105621390.021
regulation of stress activated protein kinase signaling cascadeGO:0070302420.021
negative regulation of phosphate metabolic processGO:0045936450.021
negative regulation of programmed cell deathGO:0043069720.021
gliogenesisGO:0042063800.021
neuron apoptotic processGO:0051402170.020
male meiosis cytokinesisGO:0007112260.020
convergent extensionGO:006002620.020
zymogen activationGO:0031638200.020
positive regulation of intracellular transportGO:0032388420.020
neuron projection extensionGO:1990138320.020
negative regulation of cell developmentGO:0010721620.020
cell cell adhesionGO:0098609260.019
macromolecular complex disassemblyGO:0032984370.019
regulation of purine nucleotide metabolic processGO:1900542620.019
positive regulation of nervous system developmentGO:0051962690.019
negative regulation of cell deathGO:0060548810.019
hematopoietic progenitor cell differentiationGO:000224410.019
response to radiationGO:00093141550.019
cellular response to abiotic stimulusGO:0071214580.019
regulation of anatomical structure sizeGO:00900661630.018
actin polymerization or depolymerizationGO:0008154310.018
regulation of jnk cascadeGO:0046328400.018
positive regulation of glial cell proliferationGO:006025250.018
cytokinesisGO:0000910900.018
hemopoiesisGO:0030097460.018
chemosensory behaviorGO:00076351060.018
regulation of cell growthGO:0001558430.018
regulation of organelle organizationGO:00330431960.018
Zebrafish
carboxylic acid metabolic processGO:0019752920.018
organophosphate catabolic processGO:00464341120.017
carbohydrate derivative catabolic processGO:19011361180.017
actin filament organizationGO:00070151260.017
positive regulation of nucleoside metabolic processGO:0045979470.017
cellular response to dna damage stimulusGO:00069742230.017
regulation of apoptotic processGO:00429811300.017
positive regulation of organelle organizationGO:0010638650.017
molting cycleGO:0042303560.016
regulation of small gtpase mediated signal transductionGO:0051056930.016
cellular response to organic substanceGO:00713101320.016
germarium derived oocyte fate determinationGO:0007294260.016
response to endogenous stimulusGO:00097191190.016
positive regulation of endocytosisGO:0045807220.016
eye photoreceptor cell developmentGO:0042462810.016
regulation of cell junction assemblyGO:190188820.016
multi organism behaviorGO:00517051750.016
Worm
pole plasm oskar mrna localizationGO:0045451460.016
regulation of cytoskeleton organizationGO:0051493890.016
Zebrafish
embryonic pattern specificationGO:00098801740.016
female germline ring canal formationGO:000730190.016
cytoskeleton dependent cytokinesisGO:0061640810.015
cell substrate adhesionGO:0031589100.015
nucleus organizationGO:0006997450.015
actomyosin structure organizationGO:0031032560.015
Zebrafish
regulation of microtubule depolymerizationGO:0031114240.015
jak stat cascadeGO:0007259490.015
positive regulation of hydrolase activityGO:0051345780.015
long term memoryGO:0007616620.015
sensory organ morphogenesisGO:00905962600.015
protein localization to nucleusGO:0034504550.015
negative regulation of intracellular signal transductionGO:1902532570.014
gland developmentGO:00487321910.014
developmental cell growthGO:0048588520.014
chemical homeostasisGO:0048878920.014
cell recognitionGO:00080371020.014
gtp catabolic processGO:0006184720.014
larval developmentGO:00021641040.014
positive regulation of growthGO:0045927750.014
cellular macromolecular complex assemblyGO:00346221530.014
protein polyubiquitinationGO:0000209110.014
rac protein signal transductionGO:001660130.014
regulation of cell cycleGO:00517262910.014
plasma membrane organizationGO:0007009260.014
synaptic transmissionGO:00072682880.014
salivary gland developmentGO:00074311620.014
ribosomal large subunit biogenesisGO:004227310.014
anterior posterior pattern specificationGO:00099521360.014
reproductive system developmentGO:0061458740.013
response to ionizing radiationGO:0010212320.013
dorsal ventral axon guidanceGO:003356320.013
germarium derived female germ line cyst formationGO:0030727420.013
leg disc morphogenesisGO:0007478800.013
developmental maturationGO:00217001720.013
organonitrogen compound catabolic processGO:19015651280.013
negative regulation of phosphatase activityGO:001092330.013
negative regulation of apoptotic processGO:0043066630.013
positive regulation of protein kinase activityGO:0045860250.013
regulation of glial cell differentiationGO:004568510.013
regulation of synapse assemblyGO:0051963940.013
rna processingGO:00063961470.013
regulation of cell motilityGO:2000145230.013
adult somatic muscle developmentGO:0007527140.013
regulation of phosphorylationGO:00423251470.012
immune response activating signal transductionGO:000275720.012
ras protein signal transductionGO:0007265880.012
respiratory system developmentGO:00605412130.012
cation transportGO:00068121100.012
mitochondrial membrane organizationGO:000700630.012
negative regulation of notch signaling pathwayGO:0045746410.012
maintenance of protein location in cellGO:0032507260.012
positive regulation of cell differentiationGO:0045597640.012
negative regulation of protein depolymerizationGO:1901880230.012
positive regulation of purine nucleotide metabolic processGO:1900544550.012
cell activationGO:000177590.012
pigmentationGO:0043473750.012
protein polymerizationGO:0051258420.012
oocyte constructionGO:00073081120.012
stress fiber assemblyGO:004314960.012
Zebrafish
lipid biosynthetic processGO:0008610460.012
organic hydroxy compound metabolic processGO:1901615830.012
positive regulation of macromolecule metabolic processGO:00106044050.011
Human
transmembrane transportGO:00550851390.011
blastoderm segmentationGO:00073501590.011
regulation of microtubule cytoskeleton organizationGO:0070507410.011
protein localization to organelleGO:0033365820.011
negative regulation of intrinsic apoptotic signaling pathwayGO:200124310.011
response to growth factorGO:0070848310.011
positive regulation of developmental growthGO:0048639620.011
stem cell developmentGO:0048864790.011
cortical cytoskeleton organizationGO:0030865290.011
regulation of cell adhesionGO:0030155270.011
regulation of hemocyte proliferationGO:0035206370.011
actin cytoskeleton reorganizationGO:0031532220.011
positive regulation of nucleobase containing compound metabolic processGO:00459353320.010
positive regulation of nucleotide metabolic processGO:0045981550.010
morphogenesis of a branching epitheliumGO:0061138450.010
positive regulation of apoptotic processGO:0043065470.010
regulation of viral genome replicationGO:004506940.010
nucleus localizationGO:0051647340.010

RhoGEF2 disease predictions

Disease predictions are made from cross-annotation of human disease genes to the identified functional analogs in fly and predicted with the fly functional network.

DiseaseDO term IDSizeProbabilityFunc Analog Org
cancerDOID:16200.015
Human
disease of cellular proliferationDOID:1456600.015
Human
organ system cancerDOID:005068600.015
Human
disease of anatomical entityDOID:700.012